Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Newborn Skin: Part I. Common Rashes and Skin Changes
Am Fam Physician. 2024 Mar;109(3):212-216.ABSTRACTRashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and c...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Katherine A M Snyder Adam D Voelckers Source Type: research

Emerging and re-emerging infectious diseases in pregnant women in an amazonian region: a large retrospective study from French Guiana
ConclusionThese results highlight the diversity, abundance, and dynamism of emerging and re-emerging infectious agents faced by pregnant women in the Amazon basin. Considering the maternal and neonatal adverse outcomes associated with these infections, increased efforts are required to enhance diagnosis, reporting, and treatment of these conditions. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 4, 2024 Category: Microbiology Source Type: research

A diagnosis of syphilis following a radical circumcision for suspected penile cancer
We present a case of a 70-year-old gentleman who was referred to our tertiary 2-week-wait penile cancer clinic with a penile mass that was ulcerated, painful and discharging. This was suspicious for penile cancer and a radical circumcision was performed to remove the diseased foreskin en bloc with the lesion that was arising from the inner foreskin. Histopathology did not reveal cancer; however, we identified spirochaetes in keeping with syphilis. This was confirmed on serology. The patient was referred to the genitourinary medicine team and treated with antibiotics. This case demonstrates a rare presentation of genital sy...
Source: Annals of the Royal College of Surgeons of England - April 2, 2024 Category: Surgery Authors: K H Pang A Haider A Freeman P Hadway C Bunker A Muneer H M Alnajjar Source Type: research

Secondary syphilis presenting with alopecia and leukoderma in a stable HIV-positive patient in a resource-limited setting: a case report
CONCLUSION: This case demonstrates the importance of a high index of clinical suspicion and testing for syphilis in patients presenting with atypical clinical features of secondary syphilis, such as hair loss and hypopigmentation. It also highlights the challenges in diagnosing and clinically managing syphilis in a resource-limited setting.PMID:38561779 | DOI:10.1186/s12981-024-00603-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 2, 2024 Category: Infectious Diseases Authors: Sukoluhle Khumalo Yves Mafulu Victor Williams Normusa Musarapasi Samson Haumba Nkululeko Dube Source Type: research

Secondary syphilis presenting with alopecia and leukoderma in a stable HIV-positive patient in a resource-limited setting: a case report
CONCLUSION: This case demonstrates the importance of a high index of clinical suspicion and testing for syphilis in patients presenting with atypical clinical features of secondary syphilis, such as hair loss and hypopigmentation. It also highlights the challenges in diagnosing and clinically managing syphilis in a resource-limited setting.PMID:38561779 | PMC:PMC10986119 | DOI:10.1186/s12981-024-00603-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 2, 2024 Category: Infectious Diseases Authors: Sukoluhle Khumalo Yves Mafulu Victor Williams Normusa Musarapasi Samson Haumba Nkululeko Dube Source Type: research

A diagnosis of syphilis following a radical circumcision for suspected penile cancer
We present a case of a 70-year-old gentleman who was referred to our tertiary 2-week-wait penile cancer clinic with a penile mass that was ulcerated, painful and discharging. This was suspicious for penile cancer and a radical circumcision was performed to remove the diseased foreskin en bloc with the lesion that was arising from the inner foreskin. Histopathology did not reveal cancer; however, we identified spirochaetes in keeping with syphilis. This was confirmed on serology. The patient was referred to the genitourinary medicine team and treated with antibiotics. This case demonstrates a rare presentation of genital sy...
Source: Annals of the Royal College of Surgeons of England - April 2, 2024 Category: Surgery Authors: K H Pang A Haider A Freeman P Hadway C Bunker A Muneer H M Alnajjar Source Type: research

Secondary syphilis presenting with alopecia and leukoderma in a stable HIV-positive patient in a resource-limited setting: a case report
CONCLUSION: This case demonstrates the importance of a high index of clinical suspicion and testing for syphilis in patients presenting with atypical clinical features of secondary syphilis, such as hair loss and hypopigmentation. It also highlights the challenges in diagnosing and clinically managing syphilis in a resource-limited setting.PMID:38561779 | PMC:PMC10986119 | DOI:10.1186/s12981-024-00603-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 2, 2024 Category: Infectious Diseases Authors: Sukoluhle Khumalo Yves Mafulu Victor Williams Normusa Musarapasi Samson Haumba Nkululeko Dube Source Type: research