A case of monkeypox and cytomegalovirus coinfection manifesting with crusted lesions mimicking rupiod syphilis
We present a 41-year-old man patient with untreated HIV with generalized rupioid crusted ulcerated plaques with perineal ulceration that were found to represent monkeypox and cytomegalovirus infections.PMID:38478642 | DOI:10.5070/D329562406 (Source: Dermatol Online J)
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Jean Zevallos Jhoann Aurich Jose Quiroz Source Type: research

Erythematous scaly plaques and nodules on scalp
We describe a 45-year-old man who presented with erythematous scaly plaques and nodules on his scalp. In previously reported cases, there were only descriptions of nodules as well as tumors. However, in our case, the patient presented with plaques and nodules on his scalp that quickly resolved with treatment for syphilis. It is important to recognize and treat syphilis at an early stage.PMID:38478648 | DOI:10.5070/D329562412 (Source: Dermatol Online J)
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Peiying Audrey Ho Yee Yen Gwee Choon Chiat Oh Source Type: research

Validating the implementation of an indicator reporting policies and laws on free public maternal health-related services in the era of universal health coverage: A multi-country cross-sectional study
ConclusionsFree care laws were largely accurately reported in the global MNCAH policy database. Notably, we found that women absorbed both direct and indirect costs and made both formal and informal payments for services designated as free. Therefore, the policy indicator does not provide a valid reflection of UHC in the three settings. (Source: PLoS One)
Source: PLoS One - March 13, 2024 Category: Biomedical Science Authors: Magdalene A. Odikro Source Type: research

Cerebrospinal Fluid Biomarkers of Symptomatic Neurosyphilis in People With HIV Compared with Uninfected Individuals
AbstractWe evaluated the diagnostic clinical performance characteristics (DCPC) of cerebrospinal fluid (CSF) total protein (TP), white blood cell count (WBC), and lactate (LA) with different cutoff points as adjunct biomarkers of confirmed or presumptive symptomatic neurosyphilis (NS) and the impact of HIV infection. From 5,640 participants who underwent lumbar punctures, 236 participants were included, and classified as either people with HIV (PWH) or people without HIV (PWoH) according to the CDC criteria for confirmed NS (n  = 42), presumptive NS (n = 74), systemic syphilis (SS) (n = 38), serological diagnos...
Source: Journal of NeuroVirology - March 12, 2024 Category: Neurology Source Type: research

Epidemiology of Reportable Bacterial Infectious Diseases in Saudi Arabia
ConclusionsThe future perspective of this research is to enhance disease surveillance reporting by including different variables, such as the source of infection, travel history, hospitalization, and mortality rates. The aim is to improve the sensitivity and specificity of surveillance data and focus on the mortality associated with bacterial pathogens to identify the most significant threats and set a public health priority. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - March 10, 2024 Category: Infectious Diseases Source Type: research

Secondary syphilis presenting as fever of unknown origin
Image of patient's maculopapular syphilitic rash on palmar surface of his hand, which developed about 8  weeks into his fever. Key Clinical MessageA thirty-eight year-old male presented with a seven-week history of persistent fever accompanied by recurrent night sweats, chills, arthralgias, headache, and chest tightness.Initial laboratory testing showed non-specific elevation of inflammatory markers, but was otherwise unremarkable.A palmar rash developed one week later, prompting testing for syphilis. Fluorescent treponemal antibody absorption (FTA-ABS) and rapid plasma reagin (RPR) tests were both positive.Penicillin G ...
Source: Clinical Case Reports - March 9, 2024 Category: General Medicine Authors: Hannah Eloise Wilding, Amy Hays Tags: CASE REPORT Source Type: research

Historical Trauma, Health Care Distrust, and the Legacy of Tuskegee: Implications for Nurse Practitioner Practice and Research
Nurse practitioners (NPs) represent a strong cadre of healers and researchers active in a global quest to eliminate health disparities and create health equity. Barriers to health care result in a disproportionate burden of disease/disability on marginalized groups. Historical trauma results in or contributes to health care distrust manifested as a unique type of barrier with implications for nurse practitioners in research and practice. The legacy of Tuskegee is a reminder and a sentinel exemplar of how Black American male participants in “The Tuskegee Study of Untreated Syphilis in the Negro Male” (the United States ...
Source: The Journal for Nurse Practitioners - March 8, 2024 Category: Nursing Authors: Carolyn M. Dolan, Sha'Meyah Bell Tags: Featured Article Source Type: research

Gastric syphilis displaying multiple annular lesions
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - March 7, 2024 Category: Gastroenterology Authors: Masaya Iwamuro, Takehiro Tanaka, Motoyuki Otsuka Source Type: research

Increased PrEP uptake and PrEP-RN coincide with decreased HIV diagnoses in men who have sex with men in Ottawa, Canada
CONCLUSION: Increasing PrEP uptake in Ottawa in 2017 to 2021 coincided with a significant decrease in new HIV diagnoses among men who have sex with men. PrEP uptake in Ottawa, particularly by those most at risk, is likely supported by an integrated approach via PrEP-RN, a nurse-led public health program where individuals diagnosed with syphilis or rectal gonorrhea or chlamydia receive an automatic offer of PrEP. While these findings cannot causally link PrEP-RN or PrEP with this reduction in new HIV diagnoses, these changes in HIV epidemiology in Ottawa occurred exclusively among the group targeted for PrEP. These data hig...
Source: Can Commun Dis Rep - March 5, 2024 Category: Infectious Diseases Authors: Abigail Kroch Patrick O'Byrne Lauren Orser Paul MacPherson Kristen O'Brien Lucia Light Ryu Kang Agatha Nyambi Source Type: research

The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges
Acta Derm Venereol. 2024 Mar 4;104:adv34879. doi: 10.2340/actadv.v104.34879.ABSTRACTSyphilis is currently a treatable disease, with a low incidence in most developed countries, although the prevalence has increased recently, especially among men-who-have-sex-with-men. In many of the least developed countries, however, syphilis is still a major health problem, although the problem is not comparable to the desperate situation worldwide less than 80 years ago. At that time, and for many centuries previously, syphilis dramatically affected the lives and health of individuals and threatened the well-being of many societies. Thi...
Source: Acta Derm Venereol A... - March 4, 2024 Category: Dermatology Authors: Lisa Ekselius Bengt Gerdin Anders Vahlquist Source Type: research

The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges
Acta Derm Venereol. 2024 Mar 4;104:adv34879. doi: 10.2340/actadv.v104.34879.ABSTRACTSyphilis is currently a treatable disease, with a low incidence in most developed countries, although the prevalence has increased recently, especially among men-who-have-sex-with-men. In many of the least developed countries, however, syphilis is still a major health problem, although the problem is not comparable to the desperate situation worldwide less than 80 years ago. At that time, and for many centuries previously, syphilis dramatically affected the lives and health of individuals and threatened the well-being of many societies. Thi...
Source: Acta Dermato-Venereologica - March 4, 2024 Category: Dermatology Authors: Lisa Ekselius Bengt Gerdin Anders Vahlquist Source Type: research

The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges
Acta Derm Venereol. 2024 Mar 4;104:adv34879. doi: 10.2340/actadv.v104.34879.ABSTRACTSyphilis is currently a treatable disease, with a low incidence in most developed countries, although the prevalence has increased recently, especially among men-who-have-sex-with-men. In many of the least developed countries, however, syphilis is still a major health problem, although the problem is not comparable to the desperate situation worldwide less than 80 years ago. At that time, and for many centuries previously, syphilis dramatically affected the lives and health of individuals and threatened the well-being of many societies. Thi...
Source: Acta Dermato-Venereologica - March 4, 2024 Category: Dermatology Authors: Lisa Ekselius Bengt Gerdin Anders Vahlquist Source Type: research

The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges
Acta Derm Venereol. 2024 Mar 4;104:adv34879. doi: 10.2340/actadv.v104.34879.ABSTRACTSyphilis is currently a treatable disease, with a low incidence in most developed countries, although the prevalence has increased recently, especially among men-who-have-sex-with-men. In many of the least developed countries, however, syphilis is still a major health problem, although the problem is not comparable to the desperate situation worldwide less than 80 years ago. At that time, and for many centuries previously, syphilis dramatically affected the lives and health of individuals and threatened the well-being of many societies. Thi...
Source: Acta Derm Venereol A... - March 4, 2024 Category: Dermatology Authors: Lisa Ekselius Bengt Gerdin Anders Vahlquist Source Type: research

The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges
Acta Derm Venereol. 2024 Mar 4;104:adv34879. doi: 10.2340/actadv.v104.34879.ABSTRACTSyphilis is currently a treatable disease, with a low incidence in most developed countries, although the prevalence has increased recently, especially among men-who-have-sex-with-men. In many of the least developed countries, however, syphilis is still a major health problem, although the problem is not comparable to the desperate situation worldwide less than 80 years ago. At that time, and for many centuries previously, syphilis dramatically affected the lives and health of individuals and threatened the well-being of many societies. Thi...
Source: Acta Dermato-Venereologica - March 4, 2024 Category: Dermatology Authors: Lisa Ekselius Bengt Gerdin Anders Vahlquist Source Type: research