Aminoadamantanes: from treatment of Parkinson's and Alzheimer's disease to symptom amelioration of long COVID-19 syndrome?
Expert Rev Clin Pharmacol. 2023 Feb 8:1-7. doi: 10.1080/17512433.2023.2176301. Online ahead of print.ABSTRACTINTRODUCTION: The aminoadamantanes amantadine and memantine are well known. They mainly act as N-methyl-D-aspartate antagonists.AREAS COVERED: The antiviral drug amantadine moderately ameliorates impaired motor behavior in patients with Parkinson's disease. Memantine provides beneficial effects on memory function in patients with advanced Alzheimer's disease already treated with acetylcholine esterase inhibitors. Both compounds counteract impaired monoamine neurotransmission with associated symptoms, such as depress...
Source: Expert Review of Clinical Pharmacology - February 2, 2023 Category: Drugs & Pharmacology Authors: Thomas M üller Peter Riederer Wilfried Kuhn Source Type: research
Aminoadamantanes: from treatment of Parkinson's and Alzheimer's disease to symptom amelioration of long COVID-19 syndrome?
Expert Rev Clin Pharmacol. 2023 Feb;16(2):101-107. doi: 10.1080/17512433.2023.2176301. Epub 2023 Feb 8.ABSTRACTINTRODUCTION: The aminoadamantanes amantadine and memantine are well known. They mainly act as N-methyl-D-aspartate antagonists.AREAS COVERED: The antiviral drug amantadine moderately ameliorates impaired motor behavior in patients with Parkinson's disease. Memantine provides beneficial effects on memory function in patients with advanced Alzheimer's disease already treated with acetylcholine esterase inhibitors. Both compounds counteract impaired monoamine neurotransmission with associated symptoms, such as depre...
Source: Expert Review of Clinical Pharmacology - February 2, 2023 Category: Drugs & Pharmacology Authors: Thomas M üller Peter Riederer Wilfried Kuhn Source Type: research
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial
CONCLUSIONS: Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.PMID:36722418 | DOI:10.1177/09645284221150824 (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - February 1, 2023 Category: Complementary Medicine Authors: Faezeh Khodaie Abdorreza Naser Moghadasi Amir Hooman Kazemi Baixiao Zhao Source Type: research
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial
CONCLUSIONS: Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.PMID:36722418 | DOI:10.1177/09645284221150824 (Source: Acupuncture in Medicine)
Source: Acupuncture in Medicine - February 1, 2023 Category: Complementary Medicine Authors: Faezeh Khodaie Abdorreza Naser Moghadasi Amir Hooman Kazemi Baixiao Zhao Source Type: research
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial
CONCLUSIONS: Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.PMID:36722418 | DOI:10.1177/09645284221150824 (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - February 1, 2023 Category: Complementary Medicine Authors: Faezeh Khodaie Abdorreza Naser Moghadasi Amir Hooman Kazemi Baixiao Zhao Source Type: research
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial
CONCLUSIONS: Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.PMID:36722418 | DOI:10.1177/09645284221150824 (Source: Acupuncture in Medicine)
Source: Acupuncture in Medicine - February 1, 2023 Category: Complementary Medicine Authors: Faezeh Khodaie Abdorreza Naser Moghadasi Amir Hooman Kazemi Baixiao Zhao Source Type: research
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial
CONCLUSIONS: Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.PMID:36722418 | DOI:10.1177/09645284221150824 (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - February 1, 2023 Category: Complementary Medicine Authors: Faezeh Khodaie Abdorreza Naser Moghadasi Amir Hooman Kazemi Baixiao Zhao Source Type: research
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial
CONCLUSIONS: Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.PMID:36722418 | DOI:10.1177/09645284221150824 (Source: Acupuncture in Medicine)
Source: Acupuncture in Medicine - February 1, 2023 Category: Complementary Medicine Authors: Faezeh Khodaie Abdorreza Naser Moghadasi Amir Hooman Kazemi Baixiao Zhao Source Type: research
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial
CONCLUSIONS: Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.PMID:36722418 | DOI:10.1177/09645284221150824 (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - February 1, 2023 Category: Complementary Medicine Authors: Faezeh Khodaie Abdorreza Naser Moghadasi Amir Hooman Kazemi Baixiao Zhao Source Type: research
