Pivmecillinam with Amoxicillin/Clavulanic acid as step down oral therapy in febrile Urinary Tract Infections caused by ESBL-producing Enterobacterales (PACUTI)
DiscussionIf the combination of pivmecillinam and amoxicillin/clavulanic acid is found to be non-inferior to the control drugs there are potential benefits in terms of tolerability, frequency of interactions, outpatient treatment, side effects, nosocomial infections and drive for further antimicrobial resistance compared to existing drugs.Trial registrationNCT05224401. Registered on February 4, 2022 (Source: Trials)
Source: Trials - September 2, 2023 Category: Research Source Type: clinical trials
Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy
Conditions: Biliary Atresia; Cholangitis; Anti-Bacterial Agents Interventions: Drug: Basic treatment: sulperazone + ursodeoxycholic acid + compound glycyrrhizin + methylprednisolone + vitamin AD , D , E , K + imipenem or meropenem; Drug: Prophylactic oral antibiotics: compound sulfamethoxazole tablet (SMZ/TMP) + cefaclor Sponsor: Children's Hospital of Fudan University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 29, 2023 Category: Research Source Type: clinical trials
Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension
Conditions: Haematological Malignancy; Hypogammaglobulinemia Interventions: Drug: trimethoprim-sulfamethoxazole (co-trimoxazole); Drug: amoxycillin/clavulanic acid and ciprofloxacin; Drug: Immunoglobulins Sponsor: Monash University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2023 Category: Research Source Type: clinical trials
