Podcast: From Homeless to Prisoner to Olympic Coach
 In his teens, Tony Hoffman was a BMX Amateur being featured on magazine covers. But soon after, he was a drug addict living in the streets and ultimately ending in prison. After his parole, a now clean Tony returned to the BMX world in a big way: by taking the silver medal in the 2016 UCI BMX World Championships. Since then, Tony has dedicated his life to helping others with addiction issues with his motivational speaking and special projects. Subscribe to Our Show! And Remember to Review Us! About Our Guest After paroling prison on December 13, 2008, Tony Hoffman started living out his dream, with h...
Source: World of Psychology - April 4, 2019 Category: Psychiatry & Psychology Authors: The Psych Central Show Tags: General Recovery Sports The Psych Central Show Addiction BMX Gabe Howard Olympics prison Tony Hoffman Vincent M. Wales Source Type: blogs

Patients Warming Up To Their Doctors ’ EHRs
Though many doctors may still loathe EHRs, patients have gotten more interested in and happy that their doctor has one. This, at least, is what recent data from the Kaiser Family Foundation suggests. In a recent data note, the Kaiser Family Foundation shared a batch of statistics drawn from the January 2019 KFF Health Tracking […] (Source: EMR and HIPAA)
Source: EMR and HIPAA - April 4, 2019 Category: Information Technology Authors: Anne Zieger Tags: Ambulatory EMR-EHR Health IT Company Healthcare IT Consumer EHR Perceptions EHR Privacy Concerns EHR Security Concerns Kaiser Family Foundation KFF Patient Medical Record Errors Source Type: blogs

How IBM Watson Overpromised and Underdelivered on AI Health Care
My friend Phil Shaffer, a fellow retired Nuclear Radiologist, is an avid poster on Aunt Minnie. His AM post today about AI in general and Watson in particular is worthy of a wider audience, and here you are. It is based on an Engineering article in the IEEE Spectrum:How IBM Watson Overpromised and Underdelivered on AI Health Care. This is a cautionary tale for all who have anything to do with AI...If IBM stumbled in this venue, if IBM could fall victim to hype and hubris...  Well, we all knew that. Big hype, zero output.I wouldn't bother to post this non-news, if it were not for the other questions it brings up.I...
Source: Dalai's PACS Blog - April 3, 2019 Category: Radiology Source Type: blogs

New Claims-Based Model Does Good Job Of Predicting Opioid Overdose Risk
A group of researchers has developed a model predicting the risk of opioid overdoses among Medicare beneficiaries that seems to do a better job than efforts using traditional statistical models, perhaps because it leveraged machine learning technology. Their study, which appears in JAMA Network Open, draws on Medicare claims data. Between 2017 and 2018, researchers […] (Source: EMR and HIPAA)
Source: EMR and HIPAA - April 3, 2019 Category: Information Technology Authors: Anne Zieger Tags: AI/Machine Learning EMR-EHR Health IT Company Healthcare IT Medicare Claims Data Opioid Abuse Opioid Abuse RIsk Opioid Epidemic Opioid Overdose Risk SDOH Social Determinants of Health Source Type: blogs

Chromosomally speaking, what do you know about sex? Take a quiz to find out.
Women have two X chromosomes (XX) and men have one X and one Y (XY), right? Not always, as you’ll learn from the quiz below. Men can be XX and women can be XY. And many other combinations of X and Y are possible. NIGMS Director’sEarly-Career Investigator LectureSex-Biased Genome Evolution Melissa A. Wilson, Ph.D.Arizona State University Wednesday, April 10, 201910:00-11:30 a.m. ET Lecture followed by Q&A sessionInfo on the ECI Lecture webpage You can learn more by listening to the live stream of a talk, titled “Sex-Biased Genome Evolution,” at 10 a.m. ET on April 10. The speaker,...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 3, 2019 Category: Research Authors: Matt Mills Tags: Being a Scientist Genes Chromosomes Genetics Genome Genomics Source Type: blogs

What's new in midwifery - 3rd April 2019
Some recent things you might like to know about...NICE Quality Standard QS179 - Child Abuse and Neglect (Feb 2019)Department of HealthOpen consultation: Coronial investigation of stillbirthsNHS DigitalMaternity Services Monthly Statistics December 2018, Experimental statisticsNHS England - Case studiesSurrey Heartlands Pregnancy Advice LineNHS ImprovementImplementing handovers and huddles: a framework for practice in maternity unitsResearchThe Support for New Mums Project: A protocol for a pilot randomized controlled trial designed to test a postnatal psychoeducation smartphone applicationResearch undertaken in Austra...
Source: Browsing - April 3, 2019 Category: Databases & Libraries Tags: midwifery Source Type: blogs

Mapping the Vikings using R
The commute to my workplace is 90 minutes each way. Podcasts are my friend. I’m a long-time listener of In Our Time and enjoyed the recent episode about The Danelaw. Melvyn and I hail from the same part of the world, and I learned as a child that many of the local place names there were derived from Old Norse or Danish. Notably: places ending in -by denote a farmstead, settlement or village; those ending in -thwaite mean a clearing or meadow. So how local are those names? Time for some quick and dirty maps using R. First, we’ll need a dataset of British place names. There are quite a few of these online, but t...
Source: What You're Doing Is Rather Desperate - April 3, 2019 Category: Bioinformatics Authors: nsaunders Tags: R statistics ggplot2 history maps podcast rstats viking Source Type: blogs

When DACA Recipients Seek to Match: Some Tips from the Trenches
As the Loyola University Chicago Stritch School of Medicine has been something of a flagship institution for the movement to enable qualified recipients of the Deferred Action for Childhood Arrivals (DACA) program to matriculate into medical school, we are increasingly being asked for tips for DACA recipients applying to residency. We sent our first five graduates who were current DACA recipients to residency positions on July 1, 2018, and recently matched nine more on Match Day 2019. Two of us have navigated this system as DACA recipients. So, we have some success under our belts. We’ve learned that there are ma...
Source: Academic Medicine Blog - April 2, 2019 Category: Universities & Medical Training Authors: Guest Author Tags: Featured Guest Perspective Trainee Perspective DACA Deferred Action for Childhood Arrivals medical student residency residency application Source Type: blogs

6 Clear Signs You ’ re in the Right Relationship
This is the person you are going to spend the rest of your life with. Is he the one? What if he’s not? Are you constantly wondering, “Does he like me enough to want to be with me for the rest of our lives?” Finding a long-term partner is the most important decisions you will ever make in your life. It’s actually a good thing to question it. Learning how to know if he’s the one allows you to look at your relationship in a new light. After all, you’re planning to spend the rest of your life with this person. So, you want to get this right, even with the best of efforts, it can go wrong. T...
Source: World of Psychology - March 31, 2019 Category: Psychiatry & Psychology Authors: Psych Central Guest Author Tags: Publishers Relationships YourTango attraction Conflict Management Love Partner Personality Significant Other Source Type: blogs

Sanctuary Jurisdictions in Florida Do Not Have Higher Crime Rates
Florida state Senator Joe Gruters (R-Sarasota) introduced a bill (SB 168) earlier this year to ban so-called sanctuary jurisdictions in Florida and require local governments to cooperate fully with Immigration and Customs Enforcement (ICE).   A sanctuary jurisdiction is any state or local government that has a policy to comply with fewer than 100 percent of ICE detainers, which are ICE requests for the local government to release an arrested or imprisoned person into ICE custody for deportation.  Local and state governments still pro secute illegal immigrants for crimes in sanctuary jurisdictions, but they only t...
Source: Cato-at-liberty - March 29, 2019 Category: American Health Authors: Alex Nowrasteh, Andrew Forrester Source Type: blogs

The iovera ° Cryoanalgesia Device: Interview with Tim Still, CEO of Myoscience
Myoscience, a medtech company based in California, has developed the iovera° cryoanalgesia device. The device was FDA cleared in 2013, with an additional clearance in 2017 for knee pain, and uses cryotherapy to freeze peripheral nerves to reduce pain without affecting nearby tissues. The company claims that the device is a useful alternative to opioid therapy for chronic pain. The iovera° is handheld, and can deliver precise, controlled doses of cryotherapy to specific sensory nerves through a series of needles. The needles create a cold zone around the nerve which is −20°C (-4° F). This causes the my...
Source: Medgadget - March 28, 2019 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Orthopedic Surgery Pain Management Source Type: blogs

Insignificant significance
Here's a new commentary on the concept of statistical significance which I like because it's written in plain language and its accessible to people who haven't taken statistics courses. I have discussed this before but maybe not lately. It's bothered me ever since I studied environmental toxicology back in the 1980s.In a pistachio shell, the basic idea of a P value is that you are looking at a difference between two groups of people or other entities, which differ in some other way. For example, one group has been exposed to some environmental agent and the other has not, and you want to know if they differ in their r...
Source: Stayin' Alive - March 28, 2019 Category: American Health Source Type: blogs

Snatching Defeat from the Jaws of Victory
Sadly,All the elements for swiftly legalizing marijuana in New Jersey seemed to be in place: A proposed bill was enthusiastically backed by Gov. Philip D. Murphy and had been endorsed by leaders of the Democratic-controlled State Legislature. Also, statewide polls showed support for the issue.Then the plans unraveled.Why?Some lawmakers were unsure about how to tax marijuana sales. Others feared legalization would flood the state ’s congested streets and highways with impaired drivers. Some would not be deterred from believing that marijuana was a dangerous menace to public health.A disagreement existed among lawmaker...
Source: Cato-at-liberty - March 28, 2019 Category: American Health Authors: Jeffrey Miron Source Type: blogs

Postdoc Positions in Cognitive Neuroscience of Communication at the University of Connecticut
The Cognitive Neuroscience of Communication-CT program is funded by a T32 Institutional Research Service Award from the NIH (Inge-Marie Eigsti& Emily Myers, Program Directors). The goal of this program is to provide targeted training in the cognitive neuroscience of communication disorders to predoctoral and postdoctoral scholars.  We invite applications for two-year postdoctoral fellowships, to begin in the Fall of 2019.Postdoctoral trainees will work under the supervision of one or more mentors on the CNC-CT team. These mentors are: Richard Aslin (Haskins Labs and University of Connecticut), Inge-Marie Eigsti, D...
Source: Talking Brains - March 27, 2019 Category: Neuroscience Authors: Greg Hickok Source Type: blogs

African American men respond better to treatments for advanced prostate cancer in clinical trials
Racial differences have long been evident in prostate cancer statistics. In particular, African American men are diagnosed with prostate cancer more often than white men, and they’re also nearly twice as likely to die of the disease. But new research also shows that African American men who receive the most advanced treatments for late-stage prostate cancer can live at least as long — or even longer — than their Caucasian counterparts. Why is this the case? Scientists are searching for an explanation. “The fact that African American men have better survival is of huge research interest,” said ...
Source: Harvard Health Blog - March 26, 2019 Category: Consumer Health News Authors: Charlie Schmidt Tags: Living With Prostate Cancer Men's Health Prostate Health Prostate Knowledge Treatments HPK Source Type: blogs

Last Couple of Months in Oncology with Dr. Bishal Gyawali: March 2019
By BISHAL GYAWALI MD, PhD Hey, I’m back! Well, you might not have noticed that my blogs were missing for the last three months but anyways, its good to be back. I was having a little time off blogs and social media as I was transitioning in my career but now I am back. Sometimes, it is very difficult to manage time for things that you must do versus things you enjoy doing, especially when these two don’t intersect. For me, these last few months the things I had to do were all bureaucratic while I couldn’t find the time for things I enjoy doing like writing these blogs. But now that we are back,...
Source: The Health Care Blog - March 26, 2019 Category: Consumer Health News Authors: Matthew Holt Tags: Medical Practice Physicians Bishal Gyawali Cancer drugs Clinical Trials Oncology Prostate Cancer RCTs Source Type: blogs

Simple Ways To Boost Health Care Access for People With Communication Disorders
The objectives—and perhaps even more interesting, the disparities within the objectives according to sex, educational attainment and disability status—are tracked by the Centers for Disease Control and Prevention’s (CDC) National Center for Health Statistics. We can search the CDC’s database by topic area for additional data on health care disparities. While the government works toward the Healthy People initiative, we can help improve health care access for those with communication disorders in our communities. I started by considering people’s social determinants of health in my community an...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - March 25, 2019 Category: Speech-Language Pathology Authors: Shelley D. Hutchins Tags: Audiology Health Care Private Practice Slider Speech-Language Pathology hearing loss Language Disorders Speech Disorders Source Type: blogs

Immigration ’s Popularity Is Rising Thanks to Trump
I recently reviewed Reihan Salam ’sMelting Pot or Civil War? A Son of Immigrants Makes the Case Against Open Borders.   My review is critical, but there is one major point on immigration that Salam gets right elsewhere:President Donald Trump willunderminethe cause of immigration restriction. Trump ’s uglyrhetoric from the beginning, his administration ’s casual and unnecessary cruelty in the case ofchild separations, his pandering withthe Muslim travel ban, and his consistent call for awall that will not slow down the flow of illegal immigrants and asylum seekers who turn themselves in to Border...
Source: Cato-at-liberty - March 25, 2019 Category: American Health Authors: Alex Nowrasteh Source Type: blogs

Fight Aging! Newsletter, March 25th 2019
This study defines a new clinically relevant concept of T-cell senescence-mediated inflammatory responses in the pathophysiology of abnormal glucose homeostasis. We also found that T-cell senescence is associated with systemic inflammation and alters hepatic glucose homeostasis. The rational modulation of T-cell senescence would be a promising avenue for the treatment or prevention of diabetes. Intron Retention via Alternative Splicing as a Signature of Aging https://www.fightaging.org/archives/2019/03/intron-retention-via-alternative-splicing-as-a-signature-of-aging/ In recent years researchers have inv...
Source: Fight Aging! - March 24, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Knowing how artificial intelligence works empowers clinicians to be at the forefront of using it
Physicians and other health care professionals are uniquely suited to understand artificial intelligence. They’ve studied or routinely use mathematics, data analysis, and algorithms. They comprehend pattern recognition, decision trees, rules-based systems, and statistics. These are the very components of AI.   Perhaps the only thing our premed and medical training didn’t teach us was how to […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 23, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/kathryn-peper" rel="tag" > Kathryn Peper, MD < /a > < /span > Tags: Tech Health IT Source Type: blogs

Can Access to Green Space Affect Child Development?
It’s no secret that spending time surrounded by nature is not only good for our physical health, but our mental health as well. Being in nature can benefit those with depression and has been shown to reduce anxiety and improve mood. Creativity and problem-solving are enhanced in nature and a walk in the park can improve cardiovascular function. There are so many varied benefits to embracing our natural environment. In fact, forest bathing, which involves slowing down and mindfully immersing ourselves in nature, is becoming popular around the country. Clearly many of us are aware of the benefits of being close to the...
Source: World of Psychology - March 22, 2019 Category: Psychiatry & Psychology Authors: Janet Singer Tags: Children and Teens Green and Environment Child Development Nature Source Type: blogs

Telomere Length and Mitochondrial DNA Copy Number Over the Mouse Lifespan
The science of intervention in aging has reached the point at which the research community should be undertaking a great deal more of the sort of work exhibited here. The authors of this open access paper have done the public service of producing reference data on telomere length and mitochondrial DNA copy number in multiple tissues over the mouse life span. Telomere length is a terrible metric for aging when measured in the immune cells taken from a blood sample; it varies widely between individuals, is dynamic for a given individual, dependent on day to day environmental and health factors, and trends with age only show ...
Source: Fight Aging! - March 22, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How long since your team scored 100+ points? This blog ’ s first foray into the fitzRoy R package
When this blog moved from bioinformatics to data science I ran a Twitter poll to ask whether I should start afresh at a new site or continue here. “Continue here”, you said. So let’s test the tolerance of the long-time audience and celebrate the start of the 2019 season as we venture into the world of – Australian football (AFL) statistics! I’ve been hooked on the wonderful sport of AFL since attending my first game, the ANZAC Day match between the Sydney Swans and Melbourne in 2003, and have hardly missed a Swans home game since. However, I don’t think you need to be a sports fanatic &...
Source: What You're Doing Is Rather Desperate - March 22, 2019 Category: Bioinformatics Authors: nsaunders Tags: australia sport statistics afl fitzroy Source Type: blogs

USMLE Step 1: Leveling the Playing Field – or Perpetuating Disadvantage?
By BRYAN CARMODY Let me show you some data. I’m going to show you the Match rate and mean Step 1 score for three groups of residency applicants. These are real data, compiled from the National Resident Matching Program’s (NRMP) Charting Outcomes in the Match reports. Ready? U.S. Allopathic Seniors: 92% match rate; Step 1 232.3U.S. Osteopathic Seniors: 83% match rate; Step 1 225.8International Medical Graduates, or IMGs (both U.S. and non-U.S. citizen: 53% match rate; Step 1 223.6 Now. What do you conclude when you look at these numbers? __ In the...
Source: The Health Care Blog - March 20, 2019 Category: Consumer Health News Authors: Matthew Holt Tags: Medical Practice Physicians Bryan Carmody international medical graduates Match Medical Education Medical residency Step 1 USMLE Source Type: blogs

BD Venovo Stent Approved in U.S. to Treat Iliofemoral Venous Occlusive Disease
BD (Becton Dickinson) won FDA approval for its Venovo venous stent, which is the first stent available for treating iliofemoral venous occlusive disease. Typically, arteries are the vessels that become narrow or even blocked from calcified plaque, but veins can also suffer from similar issues. The iliac and femoral veins near the groin are particularly prone to being occluded and that’s where the Venovo stent should help. The Venovo is made of nitinol and it’s made to be very flexible, so as to be able to reach the target treatment zone. It sports high radial strength, resists compression, and a variety of...
Source: Medgadget - March 18, 2019 Category: Medical Devices Authors: Editors Tags: Radiology Vascular Surgery Source Type: blogs

Fight Aging! Newsletter, March 18th 2019
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases. There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Source: Fight Aging! - March 17, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Crystal Meth Addiction
What is a Crystal Meth Addiction? Crystal meth is the name for the street drug crystal methamphetamine. Crystal meth can also be known as ice or glass, and it can be either snorted, smoked or dissolved and injected. It is a very strong and highly addictive drug. It affects the central nervous system, and crystal meth addiction has dangerous life-threatening effects. Understanding Crystal Meth Crystal meth is a man-made stimulant drug that has no legal use. It is made with methamphetamine, pseudoephedrine and a combination of other chemicals. Methamphetamine has been around for a long time, originally created to keep soldie...
Source: Cliffside Malibu - March 14, 2019 Category: Addiction Authors: Jaclyn Uloth Tags: Addiction Drug Treatment Methamphetamines Substance Abuse crystal methamphetamine meth addiction Source Type: blogs

In Later Life, We Become Less Aware Of Other People ’s Anger And Fear, But Remain Sensitive To Their Happiness
By Emma Young Most people find it easy to infer the emotional state underlying a scowl or beaming smile. But not all facial emotional signals are so obvious. Sensitivity to these less obvious emotional signals varies from one person to another and is a useful skill, improving relations with other people and benefiting psychological wellbeing. As well as varying between individuals, are there also shifts in this ability during a typical person’s life? And, if so, might these age-related changes be relevant to known high-risk periods for psychological problems and the onset of mental illness? A new study, published in ...
Source: BPS RESEARCH DIGEST - March 14, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Developmental Emotion Source Type: blogs

When Faith Alone Can ’ t Heal Depression
There is no question that religion and spirituality can help pull us out of darkness and provide the hope and inspiration that is needed to persevere through despair. Several studies over the last decade have confirmed the positive role of faith in recovery from depression. How Faith Helps Depression A 2016 study from the University of Utah School of Medicine demonstrated how religious and spiritual experiences activate the brain reward circuits. In the study 19 young-adult Mormon church members performed four tasks in response to content meant to evoke spiritual feelings. Based on the brain imaging scans (fMRI), rese...
Source: World of Psychology - March 13, 2019 Category: Psychiatry & Psychology Authors: Therese J. Borchard Tags: Brain and Behavior Depression General Inspiration & Hope Mental Health and Wellness Motivation and Inspiration Research Spirituality Stigma Emotional Resilience Faith Source Type: blogs

A New Study Supports Evolutionary Psychology ’s Explanation For Why Men And Women Want Different Attributes In Partners
By Jesse Singal When it comes to the heated subject of differences between how men and women behave, debate in psychology has centered on mate preferences and general interests. The available research shows that when it comes to (heterosexual) mating preferences, men are relatively more interested in physical beauty, while women are relatively more interested in earning capacity. As for general interests, men are more interested in physical things, while women are more interested in people. Even the staunchest evolutionary psychologists would acknowledge these are partially overlapping bell curves: There are plenty o...
Source: BPS RESEARCH DIGEST - March 13, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Dating evolutionary psych Sex Source Type: blogs

What's new in midwifery - 13th March 2019
Some things you may need to know about …NICE GuidanceNG121 – Intrapartum care for women with existing medical conditions or obstetric complications and their babies, published March 2019Health Education EnglandMaternity Workforce Strategy – Transforming the maternity workforceCase studiesAtlas of Shared Learning Implementing the Mum and BabyApp across North-West LondonReducing perineal tears duringchildbirth at Bedford Hospital NHS TrustOther case studiesHumber, Coast and Vale Health and Care Partnership - Work to improve access tospecialist community perinatal mental health services Film revie...
Source: Browsing - March 13, 2019 Category: Databases & Libraries Tags: midwifery Source Type: blogs

Keeping the art of medical satire alive
Sequels generally disappoint. Jason couldn ’t match the fear he generated in the original Friday the 13th. The sequel to the “Parachute,” a satirical piece canvassing PubMed for randomized controlled trials (RCTs) comparing parachutes to placebo, matched its brilliance — and even exceeded it, though the margin can’t be confirmed wi th statistical significance. The “Parachute,” published […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 12, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/dr-saurabh-jha" rel="tag" > Dr. Saurabh Jha < /a > < /span > Tags: Physician Cardiology Source Type: blogs

The Imperfect Count of Hate Crimes
Laws on hate crimes raise  longstanding questions of fairness both in theory and application, including (when enacted at the federal level) dangers of overextension of federal criminal law and inroads on the prohibition against double jeopardy. The role of hate crimes as culture war rallying points can make things worse. In the Jussie Smollett episode, journalists came under fire for raising questions about unlikely elements of the actor’s sto ry — Smollett had been “doubly victimized as the subject of speculation by the media industry and broader culture,” said the hea...
Source: Cato-at-liberty - March 12, 2019 Category: American Health Authors: Walter Olson Source Type: blogs

Psychologists Love To Report “Marginally Significant” Results, According To A New Analysis 
  Figure 3 from Olsson-Collentine et al, 2019: “Percentage of p values (.05
Source: BPS RESEARCH DIGEST - March 12, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Methods Source Type: blogs

Have Specific Genetic Examples of Antagonistic Pleiotropy Been Identified in Humans?
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases. There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Source: Fight Aging! - March 11, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Podcast: Talking Suicide with a Bipolar and a Schizophrenic
 Suicide is something that most people think they understand, but there are many misconceptions about it. We say it’s a serious problem, yet will mention it casually and insensitively in certain settings. In this episode, our hosts openly discuss suicide and their personal stories with trying to end their own lives.   SUBSCRIBE & REVIEW “I thought about suicide every day for as far back as I can remember.” – Gabe Howard   Highlights From ‘Suicide’ Episode [1:00] Frankly discussing suicide. [3:00] Don’t belittle a person’s suicide attempt. [7:00] Why...
Source: World of Psychology - March 11, 2019 Category: Psychiatry & Psychology Authors: A Bipolar, a Schizophrenic, and a Podcast Tags: A Bipolar, A Schizophrenic, and a Podcast Depression Schizophrenia Suicide Source Type: blogs

This is not normal(ised)
“Sydney stations where commuters fall through gaps, get stuck in lifts” blares the headline. The story tells us that: Central Station, the city’s busiest, topped the list last year with about 54 people falling through gaps Wow! Wait a minute… Central Station, the city’s busiest Some poking around in the NSW Transport Open Data portal reveals how many people enter every Sydney train station on a “typical” day in 2016, 2017 and 2018. We could manipulate those numbers in various ways to estimate total, unique passengers for FY 2017-18 but I’m going to argue that the value as-is...
Source: What You're Doing Is Rather Desperate - March 11, 2019 Category: Bioinformatics Authors: nsaunders Tags: australian news statistics smh trains transport Source Type: blogs

Better the Balance, Better the World, Better the Science
The theme for this year’s International Women’s Day is #BalanceforBetter, which encourages a more gender-balanced world to drive change and progress. This extends to science and research, statistics from WISE stated that since 2011, there has been a year on year increase in the number of women in core STEM occupations. We need to continue this good work, and head for a future where women feel more empowered and supported to enter a career in science.  To mark the day,  we spoke to Rupshi Mitra, Assistant Professor at Nanyang Technological University (NTU) and author of a paper published on F...
Source: Naturally Selected - March 8, 2019 Category: Biomedical Science Authors: Rupshi Mitra Tags: F1000 Source Type: blogs

These Violent Delights Don ’t Have Violent Ends: Study Finds No link Between Violent Video Games And Teen Aggression
By Matthew Warren Claims that violent video games lead to aggression have been around since the days of Space Invaders. When young people are exposed to violent media, the theory goes, their aggressive thoughts become more prominent, leading them to commit acts of violence. But while several studies have found results that seem to back up this idea, the evidence is far from unequivocal. Now a study published in Royal Society Open Science has failed to find any association between the time spent playing violent video games and aggressive behaviour, adding to a growing body of literature that suggests that such a link has be...
Source: BPS RESEARCH DIGEST - March 6, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Developmental Forensic Media Technology Source Type: blogs

Fear, Measles, and Protecting our Kids
This study followed 657,461 children born in Denmark from 1999 through 31 December 2010, with follow-up from 1 year of age and through 31 August 2013. Another team of researchers completed an exhaustive review of all scientific studies of the MMR and its potential problems in 2001. The results are published in the September 2001 issue of the Archives of Disease in Childhood. Those authors concluded, “While the final decision rests with the parents, the evidence of the safety and efficacy of MMR  vaccine is so overwhelmingly conclusive that health professionals should have no hesitation recommending its use....
Source: Conversations with Dr Greene - March 5, 2019 Category: Child Development Authors: Dr. Alan Greene Tags: Dr. Greene's Blog Immunizations Source Type: blogs

Using parameters in Rmarkdown
Nothing new or original here, just something that I learned about quite recently that may be useful for others. One of my more “popular” code repositories, judging by Twitter, is – well, Twitter. It mostly contains Rmarkdown reports which summarise meetings and conferences by analysing usage of their associated Twitter hashtags. The reports follow a common template where the major difference is simply the hashtag. So one way to create these reports is to use the previous one, edit to find/replace the old hashtag with the new one, and save a new file. That works…but what if we could define the hasht...
Source: What You're Doing Is Rather Desperate - March 4, 2019 Category: Bioinformatics Authors: nsaunders Tags: programming statistics automation reports rmarkdown Source Type: blogs

Your Romantic Partner Is Probably Less Intelligent Than You Think, Suggests New Study
By guest blogger David Robson It’s now well known that many of us over-estimate our own brainpower. In one study, more than 90 per cent of US college professors famously claimed to be better than average at teaching, for instance – which would be highly unlikely. Our egos blind us to our own flaws. But do we have an even more inflated view of our nearest and dearest? It seems we do – that’s the conclusion of a new paper published in Intelligence journal, which has shown that we consistently view our romantic partners as being much smarter than they really are.  The researchers, Gille...
Source: BPS RESEARCH DIGEST - March 4, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Dating Intelligence Source Type: blogs

School Choice Reduces Crime and Paternity Suits
One of the original arguments for a government-run education system is thatpublic schools are necessary for stable democratic society. After all, self-interested families might send their children to private schools that specialize in maximizing earnings rather than citizenship skills. But new evidence suggests that private schools are actually more conducive to maintaining social order than public schools. Here ’s why.Thenew study - coauthored by Dr. Patrick J. Wolf and me - used student-level data from the longitudinal evaluation of the longest-running private school voucher program in the United States. We found t...
Source: Cato-at-liberty - March 1, 2019 Category: American Health Authors: Corey A. DeAngelis Source Type: blogs

This Diary Study Just Happened To Be Taking Place When Disaster Struck, Providing A Rare Insight Into Vicarious Experience Of Traumatic Events
By Matthew Warren Major disasters clearly take a toll on the survivors who had the misfortune to go through them. But there is another group of people who can suffer mental and physical distress from disasters: those who experience them second-hand, through media coverage and conversation. After 9/11, for example, researchers found an increase in symptoms of depression and stress among Americans who hadn’t directly experienced the terrorist attacks.  But there have always been doubts about studies purporting to show evidence of vicarious distress. Because disasters occur randomly researchers are usually unable t...
Source: BPS RESEARCH DIGEST - March 1, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Mental health Source Type: blogs

A More Serious Trial Failure for Gensight's Allotopic Expression Implementation
Gensight Biologics uses allotopic expression of a mitochondrial gene, ND4, to attempt to treat the inherited blindness condition Leber hereditary optic neuropathy, in which this gene is mutated and dysfunctional. An altered copy of ND4 is introduced into the cell nucleus, and the protein produced is delivered back to the mitochondria where it is needed for correct function. A fairly standard gene therapy is used to deliver this payload into the retina. Unfortunately, after promising results from earlier trials and technology demonstrations, their late stage trials are failing. It remains to be seen as to why this is...
Source: Fight Aging! - February 28, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

BIOTRONIK ’s Orsiro Ultrathin Coronary Stent Approved in U.S.
BIOTRONIK won FDA approval for its Orsiro drug-eluting coronary stent, an ultrathin device that’s already been approved in Europe for eight years and has been implanted in more than a million patients worldwide. The Orsiro is a cobalt chromium metal stent that releases sirolimus, which helps to prevent restenosis. This is performed by BIOTRONIK’s proprietary BIOlute bioabsorbable polymer coating, which is infused with the drug and releases it as it breaks down. The stent is available as narrow as 2.25 mm up to 4.0 mm in diameter and lengths up to 40 mm, which is the longest available in the U.S. for this kind o...
Source: Medgadget - February 25, 2019 Category: Medical Devices Authors: Editors Tags: Cardiology Source Type: blogs

Fight Aging! Newsletter, February 25th 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - February 24, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Yet Again An Insightful Comment Lays The Disingenuous ADHA Exposed To Ridicule. They Really Need To Start Behaving Like Mature, Truthful Adults!
Again an anon. reader has called out the fraudulent ADHA. Quote from the comment in italics “The measure of ADHA success is clear in the national strategy (or the let’s rationale our overblown budgets).Extract from online versionAlmost five million Australians now have a record (20% of the population)[7] and, with opt-out participation arrangements due to be implemented from 2018, an e stimated 98% of the population will then have a My Health Record. In 2018, Australia will have the highest participation rate in a national health record system in the world. For the first time, members of healthcare teams will h...
Source: Australian Health Information Technology - February 24, 2019 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

When The Best You Can Get Is Zero – The BACtrack Mobile Breathalyzer Review
All drivers get into situations when they have to say no to alcohol, or have to count how much time they’ll need until sobering up completely when they have that last drink. But breathalyzers could also be parents’ good friend when dealing with teenage drinking, people who try to regulate their alcohol consumption, and nurses or doctors, who could also easily assess whether an incoming patient is under the influence of booze. A digitalized, smartphone-connected, truly 21st-century breathalyzer, the BACtrack Mobile promises to monitor blood alcohol concentration straight from your pocket – and we decided t...
Source: The Medical Futurist - February 23, 2019 Category: Information Technology Authors: nora Tags: Health Sensors & Trackers Medical Professionals Patients alcohol alcohol consumption breathalyzer device digital gadget gadgets review smartphone smartphone apps technology zero Source Type: blogs