Adding Patiromer Allows More Spironolactone in Resistant HTN, CKD Adding Patiromer Allows More Spironolactone in Resistant HTN, CKD
With or without heart failure, add-on treatment with the potassium sequestrant ' enabled ' more intensive use of the aldosterone blocker otherwise limited by hyperkalemia, according to the AMBER trial.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - September 20, 2019 Category: Neurology Tags: Cardiology News Source Type: news
New study aims to improve acne in women
A new study is looking for women with acne in Bristol to take part in a new clinical trial. Led by researchers at the Universities of Bristol and Southampton the study will investigate whether a drug called spironolactone can help improve acne in women. (Source: University of Bristol news)
Source: University of Bristol news - July 4, 2019 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School; Press Release Source Type: news
Transcriptional activation of elephant shark mineralocorticoid receptor by corticosteroids, progesterone, and spironolactone
The mineralocorticoid receptor (MR) is a nuclear receptor and part of a large and diverse family of transcription factors that also includes receptors for glucocorticoids, progesterone, androgens, and estrogens. The corticosteroid aldosterone is the physiological activator of the MR in humans and other terrestrial vertebrates; however, its activator is not known in cartilaginous fish, the oldest group of extant jawed vertebrates. Here, we analyzed the ability of corticosteroids and progesterone to activate the full-length MR from the elephant shark (Callorhinchus milii). On the basis of their measured activities, aldostero...
Source: Signal Transduction Knowledge Environment - June 3, 2019 Category: Science Authors: Katsu, Y., Kohno, S., Oka, K., Lin, X., Otake, S., Pillai, N. E., Takagi, W., Hyodo, S., Venkatesh, B., Baker, M. E. Tags: STKE Research Articles Source Type: news
Accord Healthcare Inc. Issues Voluntary Nationwide Recall of Hydrochlorothiazide Tablets USP 12.5 Mg Due to Labeling Mix-up
A 100 count bottle of Hydrochlorothiazide Tablets USP 12.5 mg has been found to contain 100 Spironolactone Tablets USP 25 mg. Since the individual lot, PW05264, of the product is involved in a potential mix-up of labeling, Accord is recalling this individual lot from the market. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 24, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Aldactone (spironolactone) vs. Lasix (furosemide)
Title: Aldactone (spironolactone) vs. Lasix (furosemide)Category: MedicationsCreated: 5/20/2019 12:00:00 AMLast Editorial Review: 5/20/2019 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - May 20, 2019 Category: Cardiology Source Type: news
Spironolactone Tablets, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 19, 2019 Category: Drugs & Pharmacology Source Type: news
Spironolactone prevents hyperkaleamia in transgender teens
According to data, published in the Journal of the Endocrine Society, only 2.2% of transgender adolescents treated with spironolactone developed hyperkalemia after starting initiation therapy.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 9, 2019 Category: Endocrinology Source Type: news
RECALL: Blood Pressure Meds Contain Wrong Drug
Accord Healthcare has recalled one lot of 12.5-milligram hydrochlorothiazide tablets because the 100-count bottle was discovered to contain 100 spironolactone tablets. (Source: WebMD Health)
Source: WebMD Health - August 29, 2018 Category: Consumer Health News Source Type: news
Blood Pressure Drug Recalled For Possible Life-Threatening Label Error
(CBS Local) – A potentially life-threatening label mix-up has led to a nationwide recall of a high blood pressure medication, according to the U.S. Food and Drug Administration.
Accord Healthcare Inc. is voluntarily recalling one lot of 12.5 mg hydrochlorothiazide tablets after a 100-count bottle of the drug was found to contain 100 tablets of another drug, spironolactone.
Accord Healthcare is recalling some bottles of Hydrochlorothiazide tablets USP, 12.5 mg, which is prescribed for high blood pressure, because they may contain the wrong pills. Photo Credit- ACCORD HEALTHCARE
Both medications are used to treat ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 29, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News blood pressure FDA Local TV Recall talkers Source Type: news
A High Blood Pressure Medication Is Being Recalled After a Potentially ‘Life-Threatening’ Labeling Mistake
A potentially “life-threatening” labeling mix-up spurred a nationwide recall of a high blood pressure medication, the Food and Drug Administration (FDA) announced.
Accord Healthcare is voluntarily recalling a single lot of 12.5-milligram hydrochlorothiazide tablets, after a pharmacy reported finding a 100-count bottle that actually contained spironolactone tablets, according to the FDA. The rest of the lot (PW05264) has been recalled due to the “potential mix-up of labeling,” but Accord says the remainder of its drugs are unaffected.
Both hydrochlorothiazide and spironolactone can be used to treat ...
Source: TIME: Health - August 29, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime Recalls Source Type: news
Accord Healthcare Inc. Issues Voluntary Nationwide Recall of Hydrochlorothiazide Tablets USP 12.5 Mg Due to Labeling Mix-up
A 100 count bottle of Hydrochlorothiazide Tablets USP 12.5 mg has been found to contain 100 Spironolactone Tablets USP 25 mg. Since the individual lot, PW05264, of the product is involved in a potential mix-up of labeling, Accord is recalling this individual lot from the market. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 28, 2018 Category: Food Science Source Type: news
Spironolactone Over Clonidine in Resistant HTN: Do You Agree? Spironolactone Over Clonidine in Resistant HTN: Do You Agree?
Dr Desai asks, would you consider spironolactone for treating patients with resistant hypertension?Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 2, 2018 Category: Consumer Health News Tags: Nephrology Viewpoint Source Type: news
Evolution of human, chicken, alligator, frog, and zebrafish mineralocorticoid receptors: Allosteric influence on steroid specificity
Although multiple steroid ligands of the glucocorticoid, mineralocorticoid, and progestin families bind to and regulate the activity of mineralocorticoid receptors (MRs), the responses to these ligands differ across species. To understand how the different domains of MRs contribute to the ligand-induced activation or inhibition of MR activity, we studied the response to eight steroids (aldosterone, 11-deoxycorticosterone, 11-deoxycortisol, cortisol, corticosterone, progesterone, 19-norprogesterone, and spironolactone) of human, chicken, alligator, frog, and zebrafish full-length MRs and truncated MRs, which lacked the N-te...
Source: Signal Transduction Knowledge Environment - July 3, 2018 Category: Science Authors: Katsu, Y., Oka, K., Baker, M. E. Tags: STKE Research Articles Source Type: news
Study: Diuretic as effective as antibiotics to treat women's acne
Spironolactone, a diuretic drug, might be an effective alternative to antibiotics for the treatment of women's acne, according to a new study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 4, 2018 Category: Consumer Health News Source Type: news
Spironolactone may be an alternative to antibiotics in women's acne treatment
(University of Pennsylvania School of Medicine) In a finding that suggests the potential for practice change that would reduce the use of antibiotics in dermatology, researchers in the Perelman School of Medicine at the University of Pennsylvania have found the diuretic drug spironolactone may be just as effective as antibiotics for the treatment of women's acne. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 4, 2018 Category: International Medicine & Public Health Source Type: news
