ATP and P2X3 Receptor in Chronic Cough
Condition: Cough Interventions: Device: Adenosine triphosphate (ATP) solution inhalation from nebuliser; Diagnostic Test: Inhalational challenge with increasing concentrations of capsaicin solutions; Device: Recording of Cough Count and frequency using the Hyfe Cough Monitor; Procedure: Collection of exhaled breath co ndensate; Diagnostic Test: Continuous laryngoscopic examination; Diagnostic Test: Sputum induction; Diagnostic Test: Spirometric measurements; Diagnostic Test: Blood sample collection Sponsors: Imperial College London; Merck Sharp & Dohme LLC Not yet recruiting...
Source: ClinicalTrials.gov - February 6, 2023 Category: Research Source Type: clinical trials
A Longitudinal, Observational Study of Primary Ciliary Dyskinesia in Adults
Condition: Primary Ciliary Dyskinesia Interventions: Diagnostic Test: Spirometry; Diagnostic Test: Multiple Breath Washout (MBW); Diagnostic Test: Mucociliary Clearance (MCC); Diagnostic Test: CT of the chest; Diagnostic Test: MRI of the chest Sponsors: ReCode Therapeutics; University of North Carolina, Chapel Hill Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 13, 2023 Category: Research Source Type: clinical trials