Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure
Conditions: Heart Failure; Pulmonary Hypertension; Pulmonary Vascular Resistance Abnormality Interventions: Diagnostic Test: non-contrast chest CT; Diagnostic Test: spirometry with diffusing lung capacity for carbon monoxide (DLCO) analysis; Diagnostic Test: Omics analysis of blood plasma obtained from pulmonary artery or peripheral blood; Diagnostic Test: supine bike exercise during right heart catheterisation; Diagnostic Test: Lung ventilation/perfusion SPECT Sponsors: Institute for Clinical and Experimental Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials

SPECT Fibroblast Activation Protein Imaging in Patients With Cardiac Disease
Conditions: Myocardial Fibrosis Interventions: Diagnostic Test: 99mTc-FAPI SPECT imaging Sponsors: Henan Institute of Cardiovascular Epidemiology Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials

Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial
Conditions: Castration-Resistant Prostate Carcinoma; Stage IVB Prostate Cancer AJCC v8 Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Other: Gallium Ga 68 Gozetotide; Drug: Lutetium Lu 177 Vipivotide Tetraxetan; Procedure: Positron Emission Tomography; Other: Questionnaire Administration; Procedure: Single Photon Emission Computed Tomography Sponsors: Jonsson Comprehensive Cancer Center; Novartis Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Conditions: Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome Interventions: Biological: Actinium Ac 225-DOTA-Daratumumab; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Computed Tomography; Biological: Daratumumab; Procedure: Echocardiography; Drug: Fludarabine; Procedure: Hematopoietic Cell Transplantation; Biological: Indium In 111-DOTA-Daratumumab; Drug: Melphalan; Procedure: Multigated Acquisition Scan; Procedure: Radionuclide Imaging; Procedure: Single Photon Emission Computed Tomography; Drug: Sirolimus; Drug: Tacrolimus; R...
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials

Artificial Intelligence and Bone Tomoscintigraphies Achieved With CZT Camera
Conditions: Bone Lesion Interventions: Diagnostic Test: Whole-body bone single photon emission tomography (SPECT) for detection or follow-up of bone metastasis Sponsors: Central Hospital, Nancy, France Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Bronx Transthyretin Amyloid Cardiomyopathy Database
Conditions: Transthyretin Cardiac Amyloidosis; Transthyretin Amyloid Cardiomyopathy Interventions: Diagnostic Test: 99mTc-pyrophosphate Single Photon Emission Computed Tomography Sponsors: Montefiore Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials

Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard
Conditions: Chest Pain; Stenosis; Myocardial Ischemia Interventions: Device: Magnetocardiography; Device: Single photon emission computed tomography (SPECT) Sponsors: Qilu Hospital of Shandong University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 13, 2024 Category: Research Source Type: clinical trials

68Ga PET/CT Versus 99mTc SPECT/CT for Lung Perfusion and Ventilation Scintigraphy; a Technical and Practical Feasibility Study
Conditions: Pulmonary Embolism; Ventilation Perfusion Mismatch Interventions: Diagnostic Test: Ga-68 V/Q PET/CT Sponsors: UMC Utrecht Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

99mTc-MIP-1404 SPECT/CT in Primary Staging of Prostate Cancer
Conditions: Prostate Cancer Interventions: Diagnostic Test: PSMA-imaging Sponsors: Turku University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials

Evaluation of a Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Conditions: Prostate Carcinoma; Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8 Interventions: Procedure: Computed Tomography; Other: Gallium Ga 68 Gozetotide; Drug: Lutetium Lu 177 Vipivotide Tetraxetan; Procedure: Positron Emission Tomography; Procedure: PSMA PET Scan; Other: Questionnaire Administration; Procedure: Single Photon Emission Computed Tomography Sponsors: Jonsson Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials

Value of Whole-body SPECT-CT CzT-based Camera (VERITON-CT) in the Assessment of Chronic Inflammatory Rheumatism With Axial Involvement and Especially of the Sacroiliac Joints
Conditions: Whole-body SPECT-CT CzT-based Sponsors: Central Hospital, Nancy, France Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
Conditions: Castration-Resistant Prostate Carcinoma; Stage IVB Prostate Cancer AJCC v8 Interventions: Procedure: Biospecimen Collection; Procedure: Bone Scan; Other: Clinical Observation; Procedure: Computed Tomography; Other: Gallium Ga 68 Gozetotide; Drug: Lutetium Lu 177 Vipivotide Tetraxetan; Procedure: Positron Emission Tomography; Other: Questionnaire Administration; Procedure: Single Photon Emission Computed Tomography Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials

99mTc-ABH2 SPECT/CT in Breast Cancer
Conditions: Breast Cancer Interventions: Drug: 99mTc-ABH2 Sponsors: Peking Union Medical College Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials

A Safety Study of 212Pb-VMT-alpha-NET in Patients With Neuroendocrine Tumors
Conditions: Neuroendocrine Tumors; Neuroendocrine Tumor of the Lung; Neuroendocrine Tumor Grade 1; Neuroendocrine Tumor Grade 2; Neuroendocrine Tumor of Pancreas Interventions: Drug: [212Pb] VMT- α-NET; Diagnostic Test: [203Pb] VMT-α-NET SPECT/CT Sponsors: David Bushnell; Holden Comprehensive Cancer Center; National Cancer Institute (NCI); Perspective Therapeutics Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer
Conditions: Castration-Resistant Prostate Carcinoma; Metastatic Prostate Adenocarcinoma; Stage IVB Prostate Cancer AJCC v8 Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Scan; Procedure: Computed Tomography; Other: Fludeoxyglucose F-18; Other: Gallium Ga 68 Gozetotide; Drug: Lutetium Lu 177 Vipivotide Tetraxetan; Procedure: Positron Emission Tomography; Procedure: Single Photon Emission Computed Tomography; Drug: Vorinostat Sponsors: University of Washington; Novartis; Institute for Prostate Cancer Research (IPCR) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 24, 2023 Category: Research Source Type: clinical trials