Characteristics of infections with ancestral, Beta and Delta variants of SARS-CoV-2 in the PHIRST-C community cohort study, South Africa, 2020-2021
Data on the characteristics of individuals with mild and asymptomatic infections with different SARS-CoV-2 variants are limited. We therefore compared the characteristics of individuals infected with ancestral... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - March 21, 2024 Category: Infectious Diseases Authors: Cheryl Cohen, Jackie Kleynhans, Anne von Gottberg, Meredith L. McMorrow, Nicole Wolter, Jinal N. Bhiman, Jocelyn Moyes, Mignon du Plessis, Maimuna Carrim, Amelia Buys, Neil A. Martinson, Kathleen Kahn, Stephen Tollman, Limakatso Lebina, Floidy Wafawanaka, Tags: Research Source Type: research

Indigofera cryptantha-induced pigmenturia in cattle in South Africa
Toxicon. 2024 Mar 18:107690. doi: 10.1016/j.toxicon.2024.107690. Online ahead of print.ABSTRACTTwo field cases of reddish-black pigmenturia occurred where cattle grazed on an established Cenchrus ciliaris (blue buffalo grass) pasture in South Africa. The pasture was noticeably invaded by Indigofera cryptantha, which was heavily grazed. Apart from the discolored urine, no other clinical abnormalities were detected. Urinalysis revealed hemoglobinuria, proteinuria and an alkaline pH. When the animals were immediately removed from the infested pasture, they made an uneventful recovery. However, a bull died when one of the herd...
Source: Toxicon - March 20, 2024 Category: Toxicology Authors: Christo J Botha Magdaleen Vosser Mohammed I A Ibrahim Elizabeth du Plessis Antoinette V Lensink Wiehan J Rudolph Luke Invernizzi Source Type: research

Indigofera cryptantha-induced pigmenturia in cattle in South Africa
Toxicon. 2024 Mar 18:107690. doi: 10.1016/j.toxicon.2024.107690. Online ahead of print.ABSTRACTTwo field cases of reddish-black pigmenturia occurred where cattle grazed on an established Cenchrus ciliaris (blue buffalo grass) pasture in South Africa. The pasture was noticeably invaded by Indigofera cryptantha, which was heavily grazed. Apart from the discolored urine, no other clinical abnormalities were detected. Urinalysis revealed hemoglobinuria, proteinuria and an alkaline pH. When the animals were immediately removed from the infested pasture, they made an uneventful recovery. However, a bull died when one of the herd...
Source: Toxicon - March 20, 2024 Category: Toxicology Authors: Christo J Botha Magdaleen Vosser Mohammed I A Ibrahim Elizabeth du Plessis Antoinette V Lensink Wiehan J Rudolph Luke Invernizzi Source Type: research

IJERPH, Vol. 21, Pages 372: The Wellbeing of Healthcare Workers during COVID-19 Era in Primary Public Health Facilities in Johannesburg, South Africa
In conclusion, the wellbeing of HCWs was aggravated during the COVID-19 era and led to low morale and compromised healthcare quality. This study advocates for promotion of greater resilience, and psychological and physical safety of HCWs through evidence-based, multilevel-multicomponent interventions at the workplace, home, and community environments in addition to strengthening public health policies and response to future pandemics. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - March 20, 2024 Category: Environmental Health Authors: Glory Makhado Busisiwe Ntuli Lindiwe Zungu Ntevhe Thovhogi Peter Modupi Mphekgwana Sogolo Lucky Lebelo Sphiwe Madiba Perpetua Modjadji Tags: Article Source Type: research

Cross-cultural variation in experiences of acceptance, camouflaging and mental health difficulties in autism: A registered report
by Connor Tom Keating, Lydia Hickman, Philippine Geelhand, Toru Takahashi, Joan Leung, Ruth Monk, Bianca Schuster, Alicia Rybicki, Teresa Marie Girolamo, Elise Clin, Fanny Papastamou, Marie Belenger, Inge-Marie Eigsti, Jennifer Louise Cook, Hirotaka Kosaka, Rieko Osu, Yuko Okamoto, Sophie Sowden-Carvalho Recent findings suggest that stigma and camouflaging contribute to mental health difficulties for autistic individuals, however, this evidence is largely based on UK samples. While studies have shown cross-cultural differences in levels of autism-related stigma, it is unclear whether camouflaging and mental health difficu...
Source: PLoS One - March 20, 2024 Category: Biomedical Science Authors: Connor Tom Keating Source Type: research

IJERPH, Vol. 21, Pages 372: The Wellbeing of Healthcare Workers during COVID-19 Era in Public Primary Health Facilities in Johannesburg, South Africa
In conclusion, the wellbeing of HCWs was aggravated during the COVID-19 era and led to low morale and compromised healthcare quality. This study advocates for promotion of greater resilience, and psychological and physical safety of HCWs through evidence-based, multilevel-multicomponent interventions at the workplace, home, and community environments in addition to strengthening public health policies and response to future pandemics. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - March 20, 2024 Category: Environmental Health Authors: Glory Makhado Busisiwe Ntuli Lindiwe Zungu Ntevhe Thovhogi Peter Modupi Mphekgwana Sogolo Lucky Lebelo Sphiwe Madiba Perpetua Modjadji Tags: Article Source Type: research

Multiplex PCR method for MinION sequencing of Bagaza virus isolated from wild caught mosquitoes in South Africa
J Virol Methods. 2024 Mar 17:114917. doi: 10.1016/j.jviromet.2024.114917. Online ahead of print.ABSTRACTBagaza virus (BAGV) is a mosquito-borne orthoflavivirus known to occur in regions of southern Europe, Africa, India and the Middle East. The virus has been associated with neurological disease and fatalities in various wild bird species. Association with human disease is not confirmed although limited serological evidence has suggested human infection. Surveillance programs for screening mosquitoes for evidence of arbovirus infection play an important role in providing information regarding the circulation and spread of ...
Source: Journal of Virological Methods - March 19, 2024 Category: Virology Authors: T R Sekee R Bubuluma D van Jaarsveldt P A Bester F J Burt Source Type: research

Association of freeze-dried plasma with 24-h mortality among trauma patients at risk for hemorrhage
CONCLUSION: We found insufficient evidence to conclude there is a difference in relative 24-h mortality among trauma patients at risk for hemorrhage who received FDP alone, blood products alone, or blood products with FDP. There may be an adjunctive role for FDP in hemorrhagic shock resuscitation in settings with significantly restricted access to blood products.PMID:38501905 | DOI:10.1111/trf.17792 (Source: Transfusion)
Source: Transfusion - March 19, 2024 Category: Hematology Authors: Nee-Kofi Mould-Millman Adane F Wogu Bailey K Fosdick Julia M Dixon Brenda L Beaty Smitha Bhaumik Hendrick J Lategan Willem Stassen Steven G Schauer Elmin Steyn Janette Verster Craig Wylie Shaheem de Vries Maria Jamison Maria Kohlbrenner Mohammed Mayet Les Source Type: research

Multiplex PCR method for MinION sequencing of Bagaza virus isolated from wild caught mosquitoes in South Africa
J Virol Methods. 2024 Mar 17:114917. doi: 10.1016/j.jviromet.2024.114917. Online ahead of print.ABSTRACTBagaza virus (BAGV) is a mosquito-borne orthoflavivirus known to occur in regions of southern Europe, Africa, India and the Middle East. The virus has been associated with neurological disease and fatalities in various wild bird species. Association with human disease is not confirmed although limited serological evidence has suggested human infection. Surveillance programs for screening mosquitoes for evidence of arbovirus infection play an important role in providing information regarding the circulation and spread of ...
Source: Journal of Virological Methods - March 19, 2024 Category: Virology Authors: T R Sekee R Bubuluma D van Jaarsveldt P A Bester F J Burt Source Type: research

Multiplex PCR method for MinION sequencing of Bagaza virus isolated from wild caught mosquitoes in South Africa
J Virol Methods. 2024 Mar 17:114917. doi: 10.1016/j.jviromet.2024.114917. Online ahead of print.ABSTRACTBagaza virus (BAGV) is a mosquito-borne orthoflavivirus known to occur in regions of southern Europe, Africa, India and the Middle East. The virus has been associated with neurological disease and fatalities in various wild bird species. Association with human disease is not confirmed although limited serological evidence has suggested human infection. Surveillance programs for screening mosquitoes for evidence of arbovirus infection play an important role in providing information regarding the circulation and spread of ...
Source: Journal of Virological Methods - March 19, 2024 Category: Virology Authors: T R Sekee R Bubuluma D van Jaarsveldt P A Bester F J Burt Source Type: research

Multiplex PCR method for MinION sequencing of Bagaza virus isolated from wild caught mosquitoes in South Africa
J Virol Methods. 2024 Mar 17:114917. doi: 10.1016/j.jviromet.2024.114917. Online ahead of print.ABSTRACTBagaza virus (BAGV) is a mosquito-borne orthoflavivirus known to occur in regions of southern Europe, Africa, India and the Middle East. The virus has been associated with neurological disease and fatalities in various wild bird species. Association with human disease is not confirmed although limited serological evidence has suggested human infection. Surveillance programs for screening mosquitoes for evidence of arbovirus infection play an important role in providing information regarding the circulation and spread of ...
Source: Journal of Virological Methods - March 19, 2024 Category: Virology Authors: T R Sekee R Bubuluma D van Jaarsveldt P A Bester F J Burt Source Type: research

Multiplex PCR method for MinION sequencing of Bagaza virus isolated from wild caught mosquitoes in South Africa
J Virol Methods. 2024 Mar 17:114917. doi: 10.1016/j.jviromet.2024.114917. Online ahead of print.ABSTRACTBagaza virus (BAGV) is a mosquito-borne orthoflavivirus known to occur in regions of southern Europe, Africa, India and the Middle East. The virus has been associated with neurological disease and fatalities in various wild bird species. Association with human disease is not confirmed although limited serological evidence has suggested human infection. Surveillance programs for screening mosquitoes for evidence of arbovirus infection play an important role in providing information regarding the circulation and spread of ...
Source: Journal of Virological Methods - March 19, 2024 Category: Virology Authors: T R Sekee R Bubuluma D van Jaarsveldt P A Bester F J Burt Source Type: research

Multiplex PCR method for MinION sequencing of Bagaza virus isolated from wild caught mosquitoes in South Africa
J Virol Methods. 2024 Mar 17:114917. doi: 10.1016/j.jviromet.2024.114917. Online ahead of print.ABSTRACTBagaza virus (BAGV) is a mosquito-borne orthoflavivirus known to occur in regions of southern Europe, Africa, India and the Middle East. The virus has been associated with neurological disease and fatalities in various wild bird species. Association with human disease is not confirmed although limited serological evidence has suggested human infection. Surveillance programs for screening mosquitoes for evidence of arbovirus infection play an important role in providing information regarding the circulation and spread of ...
Source: Journal of Virological Methods - March 19, 2024 Category: Virology Authors: T R Sekee R Bubuluma D van Jaarsveldt P A Bester F J Burt Source Type: research

Safety and immunogenicity of a subtype C ALVAC-HIV (vCP2438) vaccine prime plus bivalent subtype C gp120 vaccine boost adjuvanted with MF59 or alum in healthy adults without HIV (HVTN 107): A phase 1/2a randomized trial
ConclusionsAlthough MF59 was expected to enhance immune responses, alum induced similar responses to MF59, suggesting that the choice between these adjuvants may not be critical for the ALVAC+gp120 regimen. Trial registrationHVTN 107 was registered with the South African National Clinical Trials Registry (DOH-27-0715-4894) and ClinicalTrials.gov (NCT03284710). (Source: PLoS Medicine)
Source: PLoS Medicine - March 19, 2024 Category: Internal Medicine Authors: Zoe Moodie Source Type: research

Scientists in Antarctica track ‘baffling’ virus that could decimate penguins and other polar animals
A 23-meter-long sailboat set off last week from Argentina for Antarctica’s Weddell Sea with eight scientists, lots of cloacal swabs, and a genetic fingerprinting machine aboard. The Australis is headed for the southern continent’s teeming colonies of Adélie penguins, other seabirds, and marine mammals. The goal : to search for signs of a deadly virus that has nearly circled the world over the past 4 years, leaving behind a trail of devastated wildlife. Last month, Spanish researchers confirmed that H5N1, the highly pathogenic form of avian influenza, had finally turned up—as long ...
Source: Science of Aging Knowledge Environment - March 18, 2024 Category: Geriatrics Source Type: research