South Africa Health Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Protocol for an evaluation of adherence monitoring and support interventions among people initiating antiretroviral therapy in Cape Town, South Africa —a multiphase optimization strategy (MOST) approach using a fractional factorial design
DiscussionTo our knowledge, ours will be the first study to use the MOST framework to determine the most effective combination of HIV adherence monitoring and support intervention components for implementation in clinics in a RLS. Our findings will provide direction for pragmatic, ongoing adherence support that will be key to ending the HIV epidemic.Trial registrationClinicalTrials.gov NCT05040841. Registered on 10 September 2021. (Source: Trials)
Source: Trials - May 5, 2023 Category: Research Source Type: clinical trials

South Africa Smoking Cessation and Engagement in HIV/TB Care Care
Conditions: HIV Infections; Tuberculosis; Smoking Cessation Interventions: Behavioral: QUIT-AD; Other: Enhanced Treatment as Usual Sponsors: Massachusetts General Hospital; Boston University; University of Cape Town Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 3, 2023 Category: Research Source Type: clinical trials

Evaluating the equity impact and cost-effectiveness of digital adherence technologies with differentiated care to support tuberculosis treatment adherence in Ethiopia: protocol and analysis plan for the health economics component of a cluster randomised trial
This study is part of the ASCENT consortium, assessing DATs in South Africa, the Philippines, Ukraine, Tanzania and Ethiopia. The aim of this study is to determine the costs, cost-effectiveness and equity impact of implementing DATs in Ethiopia.Methods and designA total of 78 health facilities have been randomised (1:1:1) into one of two intervention arms or a standard-of-care arm. Approximately 50 participants from each health facility will be enrolled on the trial. Participants in facilities randomised to the intervention arms are offered a DAT linked to the ASCENT adherence platform for daily adherence monitoring and di...
Source: Trials - April 24, 2023 Category: Research Source Type: clinical trials

Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa
Condition: Meningococcal Infection (Healthy Volunteers) Interventions: Biological: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine; Biological: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine; Biological: Oral bivalent types 1 and 3; Poliomyelitis Vaccine (OPV); Biologica l: Pneumoccocal Vaccine; Biological: Measles, Mumps, and Rubella Vaccine live (MMR); Biological: DTwP-HepB-Hib-IPV vaccine; Biological: DTaP-IPV-Hib-HepB vaccine; Biological: Hepatitis A vaccine; Biological: Rotavirus vaccine; ...
Source: ClinicalTrials.gov - April 3, 2023 Category: Research Source Type: clinical trials