Quiz post: do either or both of these patients have high lateral OMI / South African flag sign?
 Written by Pendell Meyers, edits by SmithTwo patients presented with acute chest pain/pressure. Here are their ECGs:Patient 1:Patient 2:See below for " answers " , and below that for both cases." Answers " : Patient 1 shows very subtle high lateral OMI, South African flag sign. She had an acute LAD OMI in the process of reperfusion, see case below.Patient 2 has a normal variant ECG which mimics high lateral OMI, and ruled out for MI, see case below.Here is theSouth African Flag sign (Figure by Ken Grauer — with the original 12-lead from Patient 1 attached below — See his Comment from theApril 8, 2022 post in...
Source: Dr. Smith's ECG Blog - January 12, 2023 Category: Cardiology Authors: Pendell Source Type: blogs

What Biden Has Gotten Right on Immigration
David J. BierPresident Biden ’s handling of immigration is the subject of intense scrutiny and criticism from all sides. Much of this criticism is right, but the president has also implemented many positive policies. While it often acted too slowly and has much more to do, the new administration has already reversed the most important restrictionist policies imposed by the Trump administration.Major Big Picture ActionsEnding the “security” travel bansOn January 20, 2021, President Bidenfully rescinded President Trump ’s ban on immigration and certain travel for nationals of Iran, North Korea, Somalia, Libya, Syria,...
Source: Cato-at-liberty - November 29, 2022 Category: American Health Authors: David J. Bier Source Type: blogs

TWiV 949: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity a...
Source: virology blog - October 29, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs

Chest pain one day after a negative stress test
Discussion Points:The patient ’s ECG transmitted to ED providers by EMS showed T waves that are easily confused with the peaked T waves of hyperkalemia. Sometimes hyperacute T waves have this slimmer, taller appearance, and it can be difficult to distinguish them in these cases. The new STE in anterior leads helps to understan d these as hyperacute. Also, other signs of hyperkalemia were absent, as there was no P wave flattening or QRS broadening, bradycardia, new AV blocks or NSIVCD, bizarre QRS morphology, or Brugada patterning. Additionally the clinical context was clearly ACS in this case, and if there were remaining...
Source: Dr. Smith's ECG Blog - October 3, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

Weekly Overseas Health IT Links –24th September, 2022.
This article makes the case and explains what will be required to make it happen.We hear a lot about “digital health” these days. As data about our health piles up — thanks to sources like electronic health records, personal fitness apps and gadgets, and home genome test kits — weshould understand a lot more than we used to about what ’s wrong with our health and what to do about it. But having a lot of data is not enough. We have to be aware of what we have, understand what it means, and act on that understanding. While the challenges are in some ways more acute in the United States because of its fragmented sys...
Source: Australian Health Information Technology - September 24, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
September 22, 2022 Edition-----We will see the closure on the Mourning Period for QE!! In Australia tomorrow, We can then move on to the next big issue, which will surely be the progress in the Russo-Ukrainian war and the associated issues with China and Russia.The US seems – with the rest of the world – to be moving into recession.King Charles has now been to all his UK Realms and will now quietly let PM Trass get back to running the UK. God help her …In Australia we have to now get on with life and the economic disaster we seem to be facing.-----Major Issues.-----https://www.afr.com/politics/federal/oddly-enough-th...
Source: Australian Health Information Technology - September 22, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

More Insulin Biosimilars Are Forthcoming; The Market Outlook for Them
During the past few weeks, in both SEC-mandated (for publicly-held companies) earnings reports and investor presentations, plus in the business news and pharmaceutical industry trade press, we received several important, relevant updates on not one, but on FOUR insulin biosimilars currently in development from two different companies. We also know that in addition to them, insulin biosimilars are in development from at least three additional companies, plus as the " innovators " , the traditional " Big Three " insulin-makers of Lilly, Novo Nordisk and Sanofi continue making their bestsellers (for the time being, anyway).&n...
Source: Scott's Web Log - September 12, 2022 Category: Endocrinology Tags: 2022 Biosimilar Biosomilars generic insulin Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
 September 08, 2022 Edition-----In the US we are seeing the outcomes of Climate Change really of and running with droughts and fires etc. Biden amped up the partisan divide with a fiery anti-Republican speech!In Russia the last leader of Soviet Russia died.In the UK we have a new PM while in Europe the energy crisis is just getting worse.In OZ we have survived the Jobs and Skills Summit with 36 prearranged outcomes. Stage management +++ in action. The GP crisis is not being addressed fully and worries regarding the Global Economy - esp. China - worsen.-----Major Issues.-----https://www.afr.com/work-and-careers/educati...
Source: Australian Health Information Technology - September 8, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The Implications of Food-Parcel Corruption for the Right to Food during the COVID-19 Pandemic in South Africa
This article sets out to ascertain the nature of the structural implications of food-parcel... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 23, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Weekly Overseas Health IT Links – 13th August 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment-----https://ehrintelligence.com/news/va-appoints-functional-champion-for-ehr-modernization-programVA Appoints Functional Champion for EHR Modernization ProgramThe new functional champion appointment will assist the VA EHR Modernization program as it struggles with implementation delays and cost overruns, the VA stated.BySarai RodriguezAugust 05, 2022 - The Depart...
Source: Australian Health Information Technology - August 13, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Procreative Non-Maleficence: A South African Human Rights Perspective on Heritable Human Genome Editing
Donrich Thaldar (University of KwaZulu-Natal), Bonginkosi Shozi (University of KwaZulu-Natal), Procreative Non-Maleficence: A South African Human Rights Perspective on Heritable Human Genome Editing, CRISPR J. (2022): If the safety and efficacy issues relating to heritable genome editing can be resolved,... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 3, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Weekly Australian Health IT Links – 25 July, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----Quite a lot going on this week and we have had a pretty busy comment flow on the blog. Interesting how comment streams evolve!The telehealth debate continues and the Government is yet to notice what a ‘steaming pile of poo’the #myHR is!-----https://www.healthcareitnews.com/news/anz/australia-launches-digital-cancer-hub-childre...
Source: Australian Health Information Technology - July 25, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The COVID-19 TRIPS Waiver and the WTO Ministerial Decision
Peter K. Yu (Texas A&M University), The COVID-19 TRIPS Waiver and the WTO Ministerial Decision in IPR in Times of Crisis: Lessons Learned From the COVID-19 Pandemic (Jens Schovsbo, ed., Forthcoming): In October 2020, India and South Africa submitted an... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - July 22, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Chest pain, RBBB but “STEMI Negative”: Is this a false cath lab activation, or a false cancellation?
A 90 year old with a history of atrial fibrillation presented with two weeks of intermittent retrosternal chest pain lasting minutes. An hour prior to presentation it became constant and more severe, accompanied by nausea and general weakness, and the paramedics brought them to the ED as a code STEMI. Heart rate was in the 50s and other vitals normal. What do you think?     There ’s atrial fibrillation, a right bundle branch block, normal axis and normal voltages. RBBB should produce secondary ST depression and T wave inversion in the anterior leads with the RsR’ (as it does in V1). But here in...
Source: Dr. Smith's ECG Blog - July 18, 2022 Category: Cardiology Authors: Jesse McLaren Source Type: blogs

mRNA Vaccines: From Tackling A Pandemic To Treating Cancer
The story of the multi-decade uphill battle Katalin Karikó and her fellow researchers fought to prove messenger RNA can viably be used in medicine is widely known today. In just as little as two years, the world has learned about mRNA technology and how fast it can react when the need arises holding almost unlimited promises in future applications. As always is the case with “instant hits” in science, the ride was actually very long and bumpy, but more on that later.  What is mRNA? In very simple terms: messenger ribonucleic acids (or mRNAs in short) are the body’s natural way to transport messages from o...
Source: The Medical Futurist - July 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Biotechnology Future of Medicine Nanotechnology cancer cancer research covid19 vaccine research HIV mRNA messenger RNA cancer vaccine malaria malaria vaccine HIV vaccine pancreatic cancer pancreatic cancer va Source Type: blogs