Evaluating the Human Immune Response to the JYNNEOS Vaccine
Conditions: Vaccinia; Virus Diseases Interventions: Biological: JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection; Procedure: Phlebotomy; Procedure: Research bronchoscopy; Procedure: Skin punch biopsy; Procedure: Bone marrow aspiration Sponsors: Washington University School of Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

Study on Immunogenicity, Reactogenicity and Safety of the VAC Δ6 Vaccine in Volunteers Aged 18-60 Years
Conditions:   Smallpox;   Monkeypox;   Cowpox;   Vaccinia Virus Infection Interventions:   Biological: VAC∆6 vaccine (10⁷ PFU);   Biological: VAC∆6 vaccine (10⁶ PFU);   Biological: Live Smallpox Vaccine;   Other: Placebo (Sodium chloride bufus, 0.9%) Sponsor:   Federal Budgetary Research Institution State Research Center of Virology and Biotechnology " Vector " Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 6, 2023 Category: Research Source Type: clinical trials

Safety and Tolerability Study of the VAC ∆6 Vaccine in Volunteers Aged 18-40 Years
Conditions:   Smallpox;   Monkeypox;   Cowpox;   Vaccinia Virus Infection Interventions:   Biological: VAC∆6 vaccine - оnce at a dose of 10⁶ PFU;   Biological: VAC∆6 vaccine - once at a dose of 10⁷ PFU;   Biological: VAC∆6 vaccine - twice at a dose of 10⁶ PFU;   Biological: Live smallpox vaccine (Smallpox vaccine) + The OspaVir® inactivated smallpox vaccine Sponsor:   Federal Budgetary Research Institution State Research Center of Virology and Biotechnology " Vector " Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 9, 2023 Category: Research Source Type: clinical trials