Four chemometric models enhanced by Latin hypercube sampling design for quantification of anti-COVID drugs: sustainability profiling through multiple greenness, carbon footprint, blueness, and whiteness metrics
Montelukast sodium (MLK) and Levocetirizine dihydrochloride (LCZ) are widely prescribed medications with promising therapeutic potential against COVID-19. However, existing analytical methods for their quantif... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - March 18, 2024 Category: Chemistry Authors: Noha S. Katamesh, Ahmed Emad F. Abbas and Shimaa A. Mahmoud Tags: Research Source Type: research
Development of a green synchronous spectrofluorimetric technique for simultaneous determination of Montelukast sodium and Bilastine in pharmaceutical formulations
For the treatment of rhinitis and asthma, a combination of Montelukast sodium and Bilastine has just been approved. Based on the first derivative of synchronous fluorescence, the current work developed a green... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 25, 2024 Category: Chemistry Authors: Sayed M. Derayea, Khalid M. Badr El-Din, Ahmed S. Ahmed, Ahmed A. Khorshed and Mohamed Oraby Tags: Research Source Type: research
Effects of montelukast sodium combined with budesonide on pulmonary function, serum IgE levels, and EOS percentage in children with comorbid allergic rhinitis and asthma
CONCLUSION: Montelukast sodium combined with budesonide can substantially improve the pulmonary function in children with comorbid AR and asthma, alleviate their symptoms of asthma and rhinitis, and lower the IgE level and EOS percentage. In addition, therapeutic regimen, IgE and EOS are independent risk factors affecting the efficacy in patients.PMID:38186993 | PMC:PMC10767537 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - January 8, 2024 Category: Research Authors: Shasha Guo Changxing Cao Source Type: research
Association of LOX gene G473A polymorphism with the occurrence of allergic rhinitis and efficacy of montelukast sodium in children
. (Source: Cell Cycle)
Source: Cell Cycle - November 27, 2023 Category: Cytology Authors: Xikun YaoYan LiuHong JiaoWenjie MaMinliang Chena Department of Otolaryngology, Sunshine Union Hospital, Weifang, Shandong, Chinab Department of Pediatrics, Sunshine Union Hospital, Weifang, Shandong, China Source Type: research
Effects of oral cysteine leukotriene receptor antagonist-montelukast on adenoid lymphoid tissue: a histopathological study under light microscope
Conclusion: Montelukast can reduce the number of reactive cells, the number of lymphocytes in blood cells and blood vessels in adenoid lymphoid tissue, which can provide a new idea for preoperative intervention and non-surgical treatment of adenoid hypertrophy in children. However, this is only a pilot study and a longer treatment period is needed to assess the long-term effects of montelukast sodium on adenoid lymphoid tissue.Clinical Trial Registration: www.Chictr.org.cn, identifier ChiCTR2300075040. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - November 2, 2023 Category: Drugs & Pharmacology Source Type: research
Montelukast Sodium Protects against Focal Cerebral Ischemic Injury by Regulating Inflammatory Reaction via Promoting Microglia Polarization
CONCLUSION: Montelukast sodium can protect against focal cerebral ischemic injury by regulating inflammatory reaction via promoting microglia polarization.PMID:37499731 | DOI:10.1016/j.brainres.2023.148498 (Source: Brain Research)
Source: Brain Research - July 27, 2023 Category: Neurology Authors: Yanling Wang Ho Jun Yun Yuchuan Ding Huishan Du Xiaokun Geng Source Type: research
Montelukast Sodium Protects against Focal Cerebral Ischemic Injury by Regulating Inflammatory Reaction via Promoting Microglia Polarization
CONCLUSION: Montelukast sodium can protect against focal cerebral ischemic injury by regulating inflammatory reaction via promoting microglia polarization.PMID:37499731 | DOI:10.1016/j.brainres.2023.148498 (Source: Brain Research)
Source: Brain Research - July 27, 2023 Category: Neurology Authors: Yanling Wang Ho Jun Yun Yuchuan Ding Huishan Du Xiaokun Geng Source Type: research
Separation and quantitative estimation of stereo-selective enantiomers of montelukast in pharmaceutical drug substance and tablets dosage forms by using stability-indicating normal phase-HPLC method
Chirality. 2023 Jul 17. doi: 10.1002/chir.23610. Online ahead of print.ABSTRACTMontelukast sodium (MLS) is a leukotriene receptor antagonist that relieves asthma, bronchospasm, allergic rhinitis, and urticaria. A simple, robust, and stability-indicating normal phase high-performance liquid chromatography method was developed to separate and quantitatively estimate the S-enantiomer of MLS. The chiral separation was achieved using USP L51 packing material along with a mobile phase consisting of a solvent mixture (n-hexane, ethanol, and propionic acid), a flow rate of 1.0 mL/min, a detection wavelength of 284 nm, a column tem...
Source: Chirality - July 18, 2023 Category: Molecular Biology Authors: Niroja Vadagam Sharath Babu Haridasyam Muvvala Venkatanarayana Narasimha S Lakka Sanjeeva R Chinnakadoori Source Type: research
Separation and quantitative estimation of stereo-selective enantiomers of montelukast in pharmaceutical drug substance and tablets dosage forms by using stability-indicating normal phase-HPLC method
Chirality. 2023 Jul 17. doi: 10.1002/chir.23610. Online ahead of print.ABSTRACTMontelukast sodium (MLS) is a leukotriene receptor antagonist that relieves asthma, bronchospasm, allergic rhinitis, and urticaria. A simple, robust, and stability-indicating normal phase high-performance liquid chromatography method was developed to separate and quantitatively estimate the S-enantiomer of MLS. The chiral separation was achieved using USP L51 packing material along with a mobile phase consisting of a solvent mixture (n-hexane, ethanol, and propionic acid), a flow rate of 1.0 mL/min, a detection wavelength of 284 nm, a column tem...
Source: Chirality - July 18, 2023 Category: Molecular Biology Authors: Niroja Vadagam Sharath Babu Haridasyam Muvvala Venkatanarayana Narasimha S Lakka Sanjeeva R Chinnakadoori Source Type: research
Effect of budesonide combined with montelukast sodium on pulmonary function parameters and immunoglobulin levels in children with bronchial asthma
CONCLUSION: Budesonide combined with montelukast sodium in the treatment of bronchial asthma has the value of clinical application and promotion.PMID:37422792 | DOI:10.15586/aei.v51i4.897 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fangfang Chu Lei Liang Fuzhe Chen Source Type: research
Effect of budesonide combined with montelukast sodium on pulmonary function parameters and immunoglobulin levels in children with bronchial asthma
CONCLUSION: Budesonide combined with montelukast sodium in the treatment of bronchial asthma has the value of clinical application and promotion.PMID:37422792 | DOI:10.15586/aei.v51i4.897 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fangfang Chu Lei Liang Fuzhe Chen Source Type: research
Effect of budesonide combined with montelukast sodium on pulmonary function parameters and immunoglobulin levels in children with bronchial asthma
CONCLUSION: Budesonide combined with montelukast sodium in the treatment of bronchial asthma has the value of clinical application and promotion.PMID:37422792 | DOI:10.15586/aei.v51i4.897 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - July 9, 2023 Category: Allergy & Immunology Authors: Fangfang Chu Lei Liang Fuzhe Chen Source Type: research
