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Viruses, Vol. 16, Pages 648: Sosuga Virus Detected in Egyptian Rousette Bats (Rousettus aegyptiacus) in Sierra Leone
ustus Osborne Emmanuel Saidu Jonathan A. Musa Doris F. Bangura Sammuel M. T. Williams George M. Fefegula Christian Sumaila Juliet Jabaty Fatmata H. James Amara Jambai Kate Garnett Thomas F. Kamara Jonathan S. Towner Aiah Lebbie Sosuga virus (SOSV), a rare human pathogenic paramyxovirus, was first discovered in 2012 when a person became ill after working in South Sudan and Uganda. During an ecological investigation, several species of bats were sampled and tested for SOSV RNA and only one species, the Egyptian rousette bat (ERBs; Rousettus aegyptiacus), tested positive. Since that time, multipl...
Source: Viruses - April 22, 2024 Category: Virology Authors: Brian R. Amman Alusine H. Koroma Amy J. Schuh Immah Conteh Tara K. Sealy Ibrahim Foday Jonathan Johnny Ibrahim A. Bakarr Shannon L. M. Whitmer Emily A. Wright Aiah A. Gbakima James Graziano Camilla Bangura Emmanuel Kamanda Augustus Osborne Emmanuel Saidu Tags: Article Source Type: research

Engaging the public in decisions about emergency vaccine deployment strategies: Lessons from scenario-based discussions in Sierra Leone
Volume 19, Issue 1, January 2024 . (Source: Global Public Health)
Source: Global Public Health - April 16, 2024 Category: International Medicine & Public Health Authors: Anthony MansarayMahmood BanguraDeborah Watson-JonesBrian GreenwoodRose BurnsShelley Susan LeesFarba FayeBailah LeighLuisa Enriaa London School of Hygiene and Tropical Medicine, London, UKb College of Medicine and Allied Health Sciences, University of Sier Source Type: research

Using call detail records to determine mobility patterns of different socio-demographic groups in the western area of Sierra Leone during early COVID-19 crisis
Environ Plan B Urban Anal City Sci. 2023 Jun;50(5):1298-1312. doi: 10.1177/23998083231158377. Epub 2023 Jun 6.ABSTRACTHuman mobility patterns created from mobile phone call detail records (CDRs) can provide an essential resource in data-poor environments to monitor the effects of health outbreaks. Analysis of this data can be instrumental for understanding the movement pattern of populations allowing governments to set and refine policies to respond to community health risks. Building on CDR mobility analysis techniques, this research set out to test whether combining CDR mobility indicators with socio-economic information...
Source: Anal Sci - April 11, 2024 Category: Chemistry Authors: Yanchao Li Ziyu Ran Lily Tsai Sarah Williams Source Type: research

Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen
In this study, we aimed to assess the association between helminth exposure to the most prevalent parasitic infections, schistosomiasis, soil transmitted helminths infection and filariasis, and the Ebola virus glycoprotein (EBOV GP) antibody concentration in response to vaccination with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen in African and European participants using samples obtained from three international clinical trials. Methods/Principal findingsWe conducted a study in a subset of participants in the EBL2001, EBL2002 and EBL3001 clinical trials that evaluated the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen against EV...
Source: PLoS Neglected Tropical Diseases - April 11, 2024 Category: Tropical Medicine Authors: Houreratou Barry Source Type: research

Viruses, Vol. 16, Pages 558: Hepatitis E Seroprevalence and Detection of Genotype 3 Strains in Domestic Pigs from Sierra Leone Collected in 2016 and 2017
artin Eiden Hepatitis E virus (HEV) is the main cause of acute hepatitis in humans worldwide and is responsible for a large number of outbreaks especially in Africa. Human infections are mainly caused by genotypes 1 and 2 of the genus Paslahepevirus, which are exclusively associated with humans. In contrast, viruses of genotypes 3 and 4 are zoonotic and have their main reservoir in domestic and wild pigs, from which they can be transmitted to humans primarily through the consumption of meat products. Both genotypes 3 and 4 are widespread in Europe, Asia, and North America and lead to sporadic cases of hepatitis E. Howe...
Source: Viruses - April 3, 2024 Category: Virology Authors: Roland Suluku Juliet Jabaty Kerstin Fischer Sandra Diederich Martin H. Groschup Martin Eiden Tags: Brief Report Source Type: research

Alcohol use among in-school adolescents in Sierra Leone
Conclusion Our study has shown that alcohol use is prevalent among in-school adolescents in Sierra Leone. Grade level, experiences of being bullied, history of sexual intercourse, truancy at school, and previous use of marijuana were the factors influencing alcohol use among in-school adolescents. The findings emphasise the necessity of creating school-based health interventions in Sierra Leone that can effectively identify in-school adolescents potentially vulnerable to alcohol-related issues. Also, existing policies and programmes aimed at reducing alcohol use among in-school adolescents need to be strengthened. (Source: BMJ Open)
Source: BMJ Open - April 2, 2024 Category: General Medicine Authors: Osborne, A., Aboagye, R. G., Olorunsaiye, C. Z., James, P. B., Bangura, C., Seidu, A.-A., Kangbai, J. B., Ahinkorah, B. O. Tags: Open access, Public health Source Type: research

The feasibility, repeatability, validity and responsiveness of the EQ-5D-3L in Krio for patients with stroke in Sierra Leone
To assess the feasibility, repeatability, validity and responsiveness of the EQ-5D-3L in Krio for patients with stroke in Sierra Leone, the first psychometric assessment of the EQ-5D-3L to be conducted in pati... (Source: Health and Quality of Life Outcomes)
Source: Health and Quality of Life Outcomes - March 28, 2024 Category: International Medicine & Public Health Authors: Daniel Youkee, Sahr Pessima, Catherine Sackley, Marina Soley-Bori, Gibrilla F. Deen and Iain J. Marshall Tags: Research Source Type: research

Geographic Disparities in Domestic Pig Population Exposure to Ebola Viruses, Guinea, 2017-2019
Emerg Infect Dis. 2024 Apr;30(4):681-690. doi: 10.3201/eid3004.231034.ABSTRACTAlthough pigs are naturally susceptible to Reston virus and experimentally to Ebola virus (EBOV), their role in Orthoebolavirus ecology remains unknown. We tested 888 serum samples collected from pigs in Guinea during 2017-2019 (between the 2013-16 epidemic and its resurgence in 2021) by indirect ELISA against the EBOV nucleoprotein. We identified 2 hotspots of possible pig exposure by IgG titer levels: the northern coast had 48.7% of positive serum samples (37/76), and Forest Guinea, bordering Sierra Leone and Liberia, where the virus emerged an...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Sol ène Grayo Alimou Camara Bakary Doukour é Isabelle Ellis C écile Troupin Kerstin Fischer Jessica Vanhomwegen Michael White Martin H Groschup Sandra Diederich No ël Tordo Source Type: research

Impact of COVID-19 on the Utilization of HIV Testing and Linkage Services in Sierra Leone: Experience from Three Public Health Facilities in Freetown
In this study, we aimed to assess the impact of the pandemic on HIV testing and linkage services at three public health facilities in Freetown, Sierra Leone. We conducted a retrospective study to assess the impact of COVID-19 on HIV testing and linkage to treatment services (HTS) at Con naught Hospital (CH-tertiary), Lumley Government Hospital (LGH-secondary) and George Brooke Community Health Center (GBC-primary) in Freetown. Statistical analyses were conducted in Stata (16.1, StataCorp LLC, College Station, TX). Intra-pandemic HTS (2020) and HTS during recovery (2021) were compa red with pre-pandemic HTS (2019). Of the...
Source: AIDS and Behavior - March 16, 2024 Category: Infectious Diseases Source Type: research