Temporary Spinal Cord Stimulation for Herpes Zoster With Myelitis: A Case Series
Conclusions: Temporary SCS alleviated pain in cases of shingles with myelitis refractory to interventional therapy. Even in cases with myelitis, tSCS for ZAP remains an effective way to prevent PHN.PMID:38606211 | PMC:PMC11006553 | DOI:10.7759/cureus.55979 (Source: Herpes)
Source: Herpes - April 12, 2024 Category: Infectious Diseases Authors: Reon Kobayashi Asae Taketomi Eiko Hara Hitoshi Mera Katsunori Oe Source Type: research
Reliance on sources of immunization information and vaccine uptake among older adults in a rural state: The mediating role of trust
Vaccine. 2024 Apr 10:S0264-410X(24)00444-4. doi: 10.1016/j.vaccine.2024.04.030. Online ahead of print.ABSTRACTOlder adults are more vulnerable to the negative impacts of infectious diseases than younger individuals. However, regardless of the importance and effectiveness of vaccines to reduce morbidity and mortality, issues remain with vaccine hesitancy among this population. Older adults' sources of immunization information and their level of trust in those sources may play a role in their vaccination behaviors. This research aimed to better understand the role of information sources and related issues of trust as related...
Source: Vaccine - April 11, 2024 Category: Allergy & Immunology Authors: Andrea L Huseth-Zosel Heather Fuller Alexandria Hicks Paul J Carson Source Type: research
Reliance on sources of immunization information and vaccine uptake among older adults in a rural state: The mediating role of trust
Vaccine. 2024 Apr 10:S0264-410X(24)00444-4. doi: 10.1016/j.vaccine.2024.04.030. Online ahead of print.ABSTRACTOlder adults are more vulnerable to the negative impacts of infectious diseases than younger individuals. However, regardless of the importance and effectiveness of vaccines to reduce morbidity and mortality, issues remain with vaccine hesitancy among this population. Older adults' sources of immunization information and their level of trust in those sources may play a role in their vaccination behaviors. This research aimed to better understand the role of information sources and related issues of trust as related...
Source: Vaccine - April 11, 2024 Category: Allergy & Immunology Authors: Andrea L Huseth-Zosel Heather Fuller Alexandria Hicks Paul J Carson Source Type: research
Management of Herpes Zoster Infection Using a Combination of Allopathic and Herbal Medication: A Case Report
Cureus. 2024 Mar 7;16(3):e55705. doi: 10.7759/cureus.55705. eCollection 2024 Mar.ABSTRACTHerpes zoster (HZ) also known as shingles is the reactivation of varicella-zoster virus (VZV) that causes chickenpox. It usually occurs in adults after remaining dormant in the dorsal root ganglia or ganglia of the cranial nerves for several years. It typically manifests as vesicle crops in a dermatomal or "zosteriform" pattern, which shows vesicle, ulcer, and scab distribution that is unilateral, clustered, and linear in a dermatome that is supplied by a single nerve. Patients usually experience prodromal symptoms of deep, severe achi...
Source: Herpes - April 8, 2024 Category: Infectious Diseases Authors: Rosalyn Lalremtluangi Suwarna Dangore-Khasbage Rahul R Bhowate Source Type: research
Management of Herpes Zoster Infection Using a Combination of Allopathic and Herbal Medication: A Case Report
Cureus. 2024 Mar 7;16(3):e55705. doi: 10.7759/cureus.55705. eCollection 2024 Mar.ABSTRACTHerpes zoster (HZ) also known as shingles is the reactivation of varicella-zoster virus (VZV) that causes chickenpox. It usually occurs in adults after remaining dormant in the dorsal root ganglia or ganglia of the cranial nerves for several years. It typically manifests as vesicle crops in a dermatomal or "zosteriform" pattern, which shows vesicle, ulcer, and scab distribution that is unilateral, clustered, and linear in a dermatome that is supplied by a single nerve. Patients usually experience prodromal symptoms of deep, severe achi...
Source: Herpes - April 8, 2024 Category: Infectious Diseases Authors: Rosalyn Lalremtluangi Suwarna Dangore-Khasbage Rahul R Bhowate Source Type: research
Potent and long-lasting humoral and cellular immunity against varicella zoster virus induced by mRNA-LNP vaccine
In this study, we aimed to evaluate immunogenicity and memory response induced by three mRNA-LNP-based vaccine candidates targeting VZV's surface glycoprotein E (gE). C57BL/6 mice were immunized with each candidate vaccine, and humoral and cellular immune responses were assessed. Our results demonstrate that the mRNA-LNP-based vaccine candidates elicited robust and durable humoral responses specific to the gE antigen. Notably, mice vaccinated with the mRNA-LNP vaccines exhibited significantly higher antigen-specific T-cell cytokine production compared to the group receiving Shingrix®, the current standard of care vaccine....
Source: Herpes - April 4, 2024 Category: Infectious Diseases Authors: Anannya Bhattacharya Lonzaric Jan Olga Burlak Jilong Li Ghanshyam Upadhyay Katherine Williams Jinhui Dong Harrison Rohrer Michelle Pynn Andrew Simon Nathan Kuhlmann Sergei Pustylnikov Mariane B Melo Antu K Dey Source Type: research
Septic arthritis of the costovertebral joint mimicking shingles
To the Editor (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: Yoshinori Tateishi, Rentaro Oda Tags: Clinical Communication to the Editor Source Type: research
Community-Based Cross-Sectional Assessment Survey On Herpes Zoster Vaccination Practices
CONCLUSION: more efforts need to be conducted to enhance vaccine uptake in at risk populations in Saudi Arabia.PMID:38566876 | PMC:PMC10983100 | DOI:10.5455/medarh.2024.78.95-99 (Source: Herpes)
Source: Herpes - April 3, 2024 Category: Infectious Diseases Authors: Nouf F Bin Rubaian Nada Alghamdi Nada Alquorain Serene R Almuhaidib Nouf A AlShamlan Assim M AlAbdulKader Moataza M Abdel Wahab Malak A Al-Shammari Source Type: research
Community-Based Cross-Sectional Assessment Survey On Herpes Zoster Vaccination Practices
CONCLUSION: more efforts need to be conducted to enhance vaccine uptake in at risk populations in Saudi Arabia.PMID:38566876 | PMC:PMC10983100 | DOI:10.5455/medarh.2024.78.95-99 (Source: Herpes)
Source: Herpes - April 3, 2024 Category: Infectious Diseases Authors: Nouf F Bin Rubaian Nada Alghamdi Nada Alquorain Serene R Almuhaidib Nouf A AlShamlan Assim M AlAbdulKader Moataza M Abdel Wahab Malak A Al-Shammari Source Type: research
Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD
This study also found significant associations of various infections with the risk of AD, but not with the risks of other dementias. This indicates that vulnerability to infections may play a more significant role in AD than in other types of dementia, which warrants further investigation.PMID:38548241 | DOI:10.1016/j.exger.2024.112411 (Source: Experimental Gerontology)
Source: Experimental Gerontology - March 28, 2024 Category: Geriatrics Authors: Svetlana Ukraintseva Arseniy P Yashkin Igor Akushevich Konstantin Arbeev Hongzhe Duan Galina Gorbunova Eric Stallard Anatoliy Yashin Source Type: research
Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD
This study also found significant associations of various infections with the risk of AD, but not with the risks of other dementias. This indicates that vulnerability to infections may play a more significant role in AD than in other types of dementia, which warrants further investigation.PMID:38548241 | DOI:10.1016/j.exger.2024.112411 (Source: Herpes)
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Svetlana Ukraintseva Arseniy P Yashkin Igor Akushevich Konstantin Arbeev Hongzhe Duan Galina Gorbunova Eric Stallard Anatoliy Yashin Source Type: research
Baculovirus Vector-Based Varicella-Zoster Virus Vaccine as a Promising Alternative with Enhanced Safety and Therapeutic Functions
Vaccines (Basel). 2024 Mar 20;12(3):333. doi: 10.3390/vaccines12030333.ABSTRACTVaricella-zoster virus (VZV) poses lifelong risks, causing varicella and herpes zoster (HZ, shingles). Currently, varicella and HZ vaccines are predominantly live attenuated vaccines or adjuvanted subunit vaccines utilizing VZV glycoprotein E (gE). Here, we propose our vaccine candidates involving a comparative analysis between recombinant baculoviral vector vaccines (AcHERV) and a live attenuated vaccine strain, vOka. AcHERV vaccine candidates were categorized into groups encoding gE only, VZV glycoprotein B (gB) only, or both gE and gB (gE-gB)...
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Chanyeong Lee Minjee Kim Jungmin Chun Sehyun Kim Doyoung Yoon Hyeondong Lee Heewon Bang Hee-Jung Lee Hosun Park Young Bong Kim Source Type: research
Two Waves of Specific B Cell Memory Immunoreconstruction Observed in Anti-HHV1-3 IgG Kinetics after Hematopoietic Stem Cell Transplantation
CONCLUSIONS: As is typical for infancy, the kinetics of the IgG level is unique after HSCT (the decline phase is first). Host microbiome factors (e.g., HHV1-3-serostatus) should be taken into account to predict risk of non-relapse mortality and survival after HSCT. The levels of specific antibodies help in predicting prognoses and improve disease management. A lack of differentiation and the confusing bias of the assessor (i.e., observer selection bias) are the main obstacles in statistical HHV1-3 research. Such time-lapse case studies may be the first to build evidence of a pathway and an association between immune parame...
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Przemyslaw Zdziarski Andrzej Gamian Source Type: research
Herpes zoster in neuro-ophthalmology: a practical approach
Eye (Lond). 2024 Mar 27. doi: 10.1038/s41433-024-03030-3. Online ahead of print.ABSTRACTHerpes Zoster (HZ) or shingles is the reactivation of the Varicella Zoster Virus (VZV), usually along a single sensory nerve, but can affect both sensory and motor cranial nerves. Major risk factors for HZ include immunosuppressed status and age older than 60 years. In the United States, the lifetime risk of HZ is approximately 30%. Worldwide, the median incidence of HZ is 4-4.5 per 1000 person-years across the Americas, Eurasia, and Australia. HZ ophthalmicus, occurring in 10-20% of patients, is an ophthalmic emergency characterized by...
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Brendan Ka-Lok Tao Deep Soor Jonathan A Micieli Source Type: research
Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD
This study also found significant associations of various infections with the risk of AD, but not with the risks of other dementias. This indicates that vulnerability to infections may play a more significant role in AD than in other types of dementia, which warrants further investigation.PMID:38548241 | DOI:10.1016/j.exger.2024.112411 (Source: Experimental Gerontology)
Source: Experimental Gerontology - March 28, 2024 Category: Geriatrics Authors: Svetlana Ukraintseva Arseniy P Yashkin Igor Akushevich Konstantin Arbeev Hongzhe Duan Galina Gorbunova Eric Stallard Anatoliy Yashin Source Type: research
