Synthetic Lethality Nanoparticles Kill Difficult to Treat Cancers
Researchers at the University of Iowa have developed dual-action nanoparticles that have been shown, in a laboratory study, to selectively kill endometrial cancer (uterine serous carcinoma) cells. The therapeutic approach combines paclitaxel, a common chemo agent, and nintedanib, aka BIBF 1120, a new cancer drug that is typically used to hinder angiogenesis, but in the current case was used to target cancer cells with a specific mutation. The mutation that nintedanib looks for is called Loss of Function p53 that prevents normal function of tumor cells and makes them less susceptible to chemotherapy. This is because chemo r...
Source: Medgadget - December 19, 2017 Category: Medical Devices Authors: Editors Tags: Nanomedicine Oncology Source Type: blogs

To be an oncologist today is to be a part of a revolution in medicine
This article was originally published in the Oncologist. Image credit: Shutterstock.com Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 8, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/don-s-dizon" rel="tag" > Don S. Dizon, MD < /a > Tags: Physician Cancer Source Type: blogs

Minimal Reporting Guidelines for the Treatment of Cancer Patients
Minimal Reporting Guidelines for the Treatment of Cancer Patients As laboratory physicians, our contribution to patient care is knowledge:  this is the starting point from which all informed therapeutic intervention proceeds.  How that knowledge is obtained and communicated is the art and science of our profession.  These minimal diagnostic guidelines are designed to be used as an aid, not a constraint, in that process.  The guidelines are presented in a specific format out of necessity, but any format that effectively communicates the necessary information in a given patho...
Source: Oncopathology - September 5, 2011 Category: Cancer & Oncology Source Type: blogs