Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages
DiscussionThese data highlight the potential to utilize Mip inhibitors in reducing potentially harmful pro-inflammatory responses resulting from B. pseudomallei infection in macrophages. This could be of significance since overstimulation of pro-inflammatory responses can result in immunopathology, tissue damage and septic shock. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 25, 2024 Category: Microbiology Source Type: research
Hungatella hathewayi bacteremia due to acute appendicitis: A case report and a narrative review
This article presents the case of an 87-year-old Asian male admitted for a hyperosmolar hyperglycemic state with septic shock secondary to Hungatella hathewayi bacteremia originating from acute appendicitis. Remarkably, the bacterium was detected in the blood 48 hours before the emergence of clinical and radiographic evidence of acute appendicitis. Additionally, we conducted a literature review to identify all documented human infections caused by Hungatella species. Timely microbial identification in such cases is essential for implementing targeted antibiotic therapy and optimizing clinical outcomes.PMID:38521228 | DOI:1...
Source: Anaerobe - March 23, 2024 Category: Microbiology Authors: Elie Bou Sanayeh Mark Tawfik Marina Makram Georges Khattar Faris Qaqish Sudeep Acharya Janet Farag Michel Chalhoub Allison Glaser Source Type: research
Hungatella hathewayi bacteremia due to acute appendicitis: A case report and a narrative review
This article presents the case of an 87-year-old Asian male admitted for a hyperosmolar hyperglycemic state with septic shock secondary to Hungatella hathewayi bacteremia originating from acute appendicitis. Remarkably, the bacterium was detected in the blood 48 hours before the emergence of clinical and radiographic evidence of acute appendicitis. Additionally, we conducted a literature review to identify all documented human infections caused by Hungatella species. Timely microbial identification in such cases is essential for implementing targeted antibiotic therapy and optimizing clinical outcomes.PMID:38521228 | DOI:1...
Source: Anaerobe - March 23, 2024 Category: Microbiology Authors: Elie Bou Sanayeh Mark Tawfik Marina Makram Georges Khattar Faris Qaqish Sudeep Acharya Janet Farag Michel Chalhoub Allison Glaser Source Type: research
Hungatella hathewayi bacteremia due to acute appendicitis: A case report and a narrative review
This article presents the case of an 87-year-old Asian male admitted for a hyperosmolar hyperglycemic state with septic shock secondary to Hungatella hathewayi bacteremia originating from acute appendicitis. Remarkably, the bacterium was detected in the blood 48 hours before the emergence of clinical and radiographic evidence of acute appendicitis. Additionally, we conducted a literature review to identify all documented human infections caused by Hungatella species. Timely microbial identification in such cases is essential for implementing targeted antibiotic therapy and optimizing clinical outcomes.PMID:38521228 | DOI:1...
Source: Anaerobe - March 23, 2024 Category: Microbiology Authors: Elie Bou Sanayeh Mark Tawfik Marina Makram Georges Khattar Faris Qaqish Sudeep Acharya Janet Farag Michel Chalhoub Allison Glaser Source Type: research
