Rurality, healthcare and crises: Investigating experiences, differences, and changes to medical care for people living in rural areas
Health Place. 2024 Mar 16;87:103217. doi: 10.1016/j.healthplace.2024.103217. Online ahead of print.ABSTRACTHealthcare provision in rural areas is a global challenge, characterised by a dispersed patient population, difficulties in the recruitment and retention of healthcare professionals and a physical distance from hospital care. This research brings together both public and doctor perspectives to explore the experience of healthcare across rural Scotland, against the backdrop of contemporary crises, including a global pandemic and extreme weather events. We draw on two studies on rural healthcare provision to understand ...
Source: Health and Place - March 17, 2024 Category: Environmental Health Authors: Andrew S Maclaren Louise Locock Zo ë Skea Diane Sk åtun Philip Wilson Source Type: research

Rurality, healthcare and crises: Investigating experiences, differences, and changes to medical care for people living in rural areas
Health Place. 2024 Mar 16;87:103217. doi: 10.1016/j.healthplace.2024.103217. Online ahead of print.ABSTRACTHealthcare provision in rural areas is a global challenge, characterised by a dispersed patient population, difficulties in the recruitment and retention of healthcare professionals and a physical distance from hospital care. This research brings together both public and doctor perspectives to explore the experience of healthcare across rural Scotland, against the backdrop of contemporary crises, including a global pandemic and extreme weather events. We draw on two studies on rural healthcare provision to understand ...
Source: Health and Place - March 17, 2024 Category: Environmental Health Authors: Andrew S Maclaren Louise Locock Zo ë Skea Diane Sk åtun Philip Wilson Source Type: research

Integrating Shared Socioeconomic Pathway-informed adaptation into temperature-related mortality projections under climate change
Environ Res. 2024 Mar 14:118731. doi: 10.1016/j.envres.2024.118731. Online ahead of print.ABSTRACTThe extent to which populations will successfully adapt to continued warming temperatures will be a crucial factor in determining future health burdens. Previous health impact assessments of future temperature-related mortality burdens mostly disregard adaptation or make simplistic assumptions. We apply a novel evidence-based approach to model adaptation that takes into account the fact that adaptation potential is likely to vary at different temperatures. Temporal changes in age-specific mortality risk associated with low and...
Source: Environmental Research - March 16, 2024 Category: Environmental Health Authors: Kai Wan Shakoor Hajat Ruth M Doherty Zhiqiang Feng Source Type: research

Integrating Shared Socioeconomic Pathway-informed adaptation into temperature-related mortality projections under climate change
Environ Res. 2024 Mar 14:118731. doi: 10.1016/j.envres.2024.118731. Online ahead of print.ABSTRACTThe extent to which populations will successfully adapt to continued warming temperatures will be a crucial factor in determining future health burdens. Previous health impact assessments of future temperature-related mortality burdens mostly disregard adaptation or make simplistic assumptions. We apply a novel evidence-based approach to model adaptation that takes into account the fact that adaptation potential is likely to vary at different temperatures. Temporal changes in age-specific mortality risk associated with low and...
Source: Environmental Research - March 16, 2024 Category: Environmental Health Authors: Kai Wan Shakoor Hajat Ruth M Doherty Zhiqiang Feng Source Type: research

Police custody in rural Scotland: negotiating boundaries, risk and  organisational change
Police custody in rural Scotland: negotiating boundaries, risk and organisational change Andrew Wooff Policing: An International Journal, Vol. ahead-of-print, No. ahead-of-print, pp.- This paper explores the challenging nexus of police custody, risk and intra-organisational boundaries in the context of a recently reformed national police service. Police custody is an often-hidden aspect of policing, away from the public gaze and scrutiny. Although there is increasing recognition of the importance of rural policing (e.g. Harkness (2020); Mawby and Yarwood (2011); Ruddell and Jones (2020); Yarwood and Wooff (2016)), there h...
Source: Policing: An International Journal of Police Strategies and Management - March 15, 2024 Category: Criminology Authors: Andrew Wooff Source Type: research

Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies
CONCLUSION: IS is prognostic in stage III CRC treated with FOLFOX or CAPOX, including within clinically relevant tumor subgroups. Possible variation in IS prognostic value by age and MMR status, and prediction of benefit from extended adjuvant therapy merit validation.PMID:38484206 | DOI:10.1200/JCO.23.01648 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Enric Domingo Caroline Kelly Jennifer Hay Owen Sansom Noori Maka Karin Oien Tim Iveson Mark Saunders Rachel Kerr Ian Tomlinson Joanne Edwards Andrea Harkin Marta Nowak Viktor Koelzer Alistair Easton Ioannis Boukovinas Eleni Moustou Ippokratis Messaritakis Source Type: research

Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies
CONCLUSION: IS is prognostic in stage III CRC treated with FOLFOX or CAPOX, including within clinically relevant tumor subgroups. Possible variation in IS prognostic value by age and MMR status, and prediction of benefit from extended adjuvant therapy merit validation.PMID:38484206 | DOI:10.1200/JCO.23.01648 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Enric Domingo Caroline Kelly Jennifer Hay Owen Sansom Noori Maka Karin Oien Tim Iveson Mark Saunders Rachel Kerr Ian Tomlinson Joanne Edwards Andrea Harkin Marta Nowak Viktor Koelzer Alistair Easton Ioannis Boukovinas Eleni Moustou Ippokratis Messaritakis Source Type: research

Association between benzodiazepine coprescription and mortality in people on opioid replacement therapy: a population-based cohort study
Conclusion Coprescription of BZDs in ORT was associated with an increased risk of all-cause mortality, although with a small effect size than the international literature. Coprescribing was also associated with longer retention in treatment. Risk from BZD coprescription needs to be balanced against the risk from illicit BZDs and unplanned treatment discontinuation. A randomised controlled trial is urgently needed to provide a clear clinical direction. Trial registration number NCT04622995. (Source: BMJ Open)
Source: BMJ Open - March 14, 2024 Category: General Medicine Authors: Best, C. S., Matheson, C., Robertson, J., Ritchie, T., Cowden, F., Dumbrell, J., Duncan, C., Kessavalou, K., Woolston, C., Schofield, J. Tags: Open access, Addiction Source Type: research

Validation of the emergency surgery score (ESS) in a UK patient population and comparison with NELA scoring: a retrospective multicentre cohort study
CONCLUSIONS: In the UK population, ESS and NELA both predict 30-day mortality and ICU admission with no statistically significant difference but with higher c-statistics for NELA score. Both scores have certain advantages, with ESS being validated for a wider range of outcomes.PMID:38478020 | DOI:10.1308/rcsann.2023.0105 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 13, 2024 Category: Surgery Authors: D Clinch A Dorken-Gallastegi D Argandykov A Gebran J A Proano Zamudio C S Wong N Clinch L Haddow K Simpson E Imbert Rje Skipworth S J Moug Hma Kaafarani D Damaskos Source Type: research

Validation of the emergency surgery score (ESS) in a UK patient population and comparison with NELA scoring: a retrospective multicentre cohort study
CONCLUSIONS: In the UK population, ESS and NELA both predict 30-day mortality and ICU admission with no statistically significant difference but with higher c-statistics for NELA score. Both scores have certain advantages, with ESS being validated for a wider range of outcomes.PMID:38478020 | DOI:10.1308/rcsann.2023.0105 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 13, 2024 Category: Surgery Authors: D Clinch A Dorken-Gallastegi D Argandykov A Gebran J A Proano Zamudio C S Wong N Clinch L Haddow K Simpson E Imbert Rje Skipworth S J Moug Hma Kaafarani D Damaskos Source Type: research

Validation of the emergency surgery score (ESS) in a UK patient population and comparison with NELA scoring: a retrospective multicentre cohort study
CONCLUSIONS: In the UK population, ESS and NELA both predict 30-day mortality and ICU admission with no statistically significant difference but with higher c-statistics for NELA score. Both scores have certain advantages, with ESS being validated for a wider range of outcomes.PMID:38478020 | DOI:10.1308/rcsann.2023.0105 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 13, 2024 Category: Surgery Authors: D Clinch A Dorken-Gallastegi D Argandykov A Gebran J A Proano Zamudio C S Wong N Clinch L Haddow K Simpson E Imbert Rje Skipworth S J Moug Hma Kaafarani D Damaskos Source Type: research

Validation of the emergency surgery score (ESS) in a UK patient population and comparison with NELA scoring: a retrospective multicentre cohort study
CONCLUSIONS: In the UK population, ESS and NELA both predict 30-day mortality and ICU admission with no statistically significant difference but with higher c-statistics for NELA score. Both scores have certain advantages, with ESS being validated for a wider range of outcomes.PMID:38478020 | DOI:10.1308/rcsann.2023.0105 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 13, 2024 Category: Surgery Authors: D Clinch A Dorken-Gallastegi D Argandykov A Gebran J A Proano Zamudio C S Wong N Clinch L Haddow K Simpson E Imbert Rje Skipworth S J Moug Hma Kaafarani D Damaskos Source Type: research

Validation of the emergency surgery score (ESS) in a UK patient population and comparison with NELA scoring: a retrospective multicentre cohort study
CONCLUSIONS: In the UK population, ESS and NELA both predict 30-day mortality and ICU admission with no statistically significant difference but with higher c-statistics for NELA score. Both scores have certain advantages, with ESS being validated for a wider range of outcomes.PMID:38478020 | DOI:10.1308/rcsann.2023.0105 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 13, 2024 Category: Surgery Authors: D Clinch A Dorken-Gallastegi D Argandykov A Gebran J A Proano Zamudio C S Wong N Clinch L Haddow K Simpson E Imbert Rje Skipworth S J Moug Hma Kaafarani D Damaskos Source Type: research

HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank
Conclusions Male and female p.C282Y homozygotes experienced greater excess morbidity than previously documented, including those undiagnosed with haemochromatosis in the community. As haemochromatosis diagnosis rates were low at baseline despite treatment being considered effective, trials of screening to identify people with p.C282Y homozygosity early appear justified. (Source: BMJ Open)
Source: BMJ Open - March 13, 2024 Category: General Medicine Authors: Lucas, M. R., Atkins, J. L., Pilling, L. C., Shearman, J. D., Melzer, D. Tags: Open access, Epidemiology Source Type: research

A qualitative study exploring the challenges and enablers of pharmacists with a recent background in community pharmacy transitioning into primary care
ConclusionPharmacists in our study reported a range of challenges (such as examination skills, improved clinical and therapeutics knowledge) required to practice in primary care, while their regular patient contact and knowledge of community pharmacy workings enabled their transition. Previous sectors of practice should be taken into consideration when inducting pharmacists into a new role and background specific inductions may need to be implemented to support these pharmacists work autonomously at an advanced level. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - March 13, 2024 Category: Drugs & Pharmacology Source Type: research