43 Evaluation of invasive nodal staging practice in lung cancer
Accurate lung cancer staging is essential for prognostication and treatment planning, with intrathoracic lymph node assessment a key component. NICE recommends sampling enlarged (>10 mm short axis on CT) or PET-positive thoracic nodes, with systematic assessment by EBUS. A Public Health Scotland Quality Performance Indicator states that at least 80% of patients with NSCLC and possible mediastinal spread should undergo mediastinal node sampling, but in 2021 this was only achieved in 68.7% of cases Scotland-wide. (Source: Lung Cancer)
Source: Lung Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Alexandra Teagle, Fraser Millar, David Dorward, Santiago Giavedoni, Adam Marshall Tags: Diagnosis and Staging Source Type: research

23 Evaluation of pulmonary rehabilitation pilot service in Inverclyde Royal Hospital
Lung cancer causes the greatest cancer mortality in Scotland and is a focus in the Scottish Government's cancer strategy. Prehabilitation optimises patients ’ physical fitness and mental well-being pre-cancer treatment. A prehabilitation service was introduced in December 2022 at Inverclyde Royal Hospital. It offered physiotherapy, dietetic information, smoking cessation, access to financial support, psychological and symptom control. (Source: Lung Cancer)
Source: Lung Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Zhen Shun Ong, Claribel Patrice Louise Simmons, Pamela Dalrymple Tags: Clinical Networks and Pathways Source Type: research

Associations Between Recent Contraceptive Use and First Sex Behaviors of Scottish Adolescents: A Brief Report
. (Source: International Journal of Sexual Health)
Source: International Journal of Sexual Health - March 31, 2024 Category: Sexual Medicine Authors: Malachi WillisJudith MabelisDorothy CurrieJudith BrownJoanna Inchleya MRC/CSO Social and Public Health Sciences Unit, School of Health and Wellbeing, University of Glasgow, Glasgow, UKb School of Medicine, University of St Andrews, St Andrews, UK Source Type: research

Increase in invasive < em > Streptococcus pyogenes < /em > M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
Euro Surveill. 2024 Mar;29(13). doi: 10.2807/1560-7917.ES.2024.29.13.2400129.ABSTRACTGroup A Streptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Iceland.PMID:...
Source: Euro Surveill - March 29, 2024 Category: Infectious Diseases Authors: Stephen B Beres Randall J Olsen S Wesley Long Ross Langley Thomas Williams Helga Erlendsdottir Andrew Smith Karl G Kristinsson James M Musser Source Type: research

Increase in invasive < em > Streptococcus pyogenes < /em > M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
Euro Surveill. 2024 Mar;29(13):2400129. doi: 10.2807/1560-7917.ES.2024.29.13.2400129.ABSTRACTGroup A Streptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Icela...
Source: Euro Surveill - March 29, 2024 Category: Infectious Diseases Authors: Stephen B Beres Randall J Olsen S Wesley Long Ross Langley Thomas Williams Helga Erlendsdottir Andrew Smith Karl G Kristinsson James M Musser Source Type: research

Increase in invasive < em > Streptococcus pyogenes < /em > M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
Euro Surveill. 2024 Mar;29(13):2400129. doi: 10.2807/1560-7917.ES.2024.29.13.2400129.ABSTRACTGroup A Streptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Icela...
Source: Euro Surveill - March 29, 2024 Category: Infectious Diseases Authors: Stephen B Beres Randall J Olsen S Wesley Long Ross Langley Thomas Williams Helga Erlendsdottir Andrew Smith Karl G Kristinsson James M Musser Source Type: research

Increase in invasive < em > Streptococcus pyogenes < /em > M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
Euro Surveill. 2024 Mar;29(13):2400129. doi: 10.2807/1560-7917.ES.2024.29.13.2400129.ABSTRACTGroup A Streptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Icela...
Source: Euro Surveill - March 29, 2024 Category: Infectious Diseases Authors: Stephen B Beres Randall J Olsen S Wesley Long Ross Langley Thomas Williams Helga Erlendsdottir Andrew Smith Karl G Kristinsson James M Musser Source Type: research

Increase in invasive < em > Streptococcus pyogenes < /em > M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
Euro Surveill. 2024 Mar;29(13):2400129. doi: 10.2807/1560-7917.ES.2024.29.13.2400129.ABSTRACTGroup A Streptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Icela...
Source: Euro Surveill - March 29, 2024 Category: Infectious Diseases Authors: Stephen B Beres Randall J Olsen S Wesley Long Ross Langley Thomas Williams Helga Erlendsdottir Andrew Smith Karl G Kristinsson James M Musser Source Type: research

Increase in invasive < em > Streptococcus pyogenes < /em > M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
Euro Surveill. 2024 Mar;29(13):2400129. doi: 10.2807/1560-7917.ES.2024.29.13.2400129.ABSTRACTGroup A Streptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Icela...
Source: Euro Surveill - March 29, 2024 Category: Infectious Diseases Authors: Stephen B Beres Randall J Olsen S Wesley Long Ross Langley Thomas Williams Helga Erlendsdottir Andrew Smith Karl G Kristinsson James M Musser Source Type: research

Pandemic policymaking affecting older adult volunteers during and after the COVID-19 public health crisis in the four nations of the UK
This study aims to critically examine the effects of COVID-19 social discourses and policy decisions specifically on older adult volunteers in the UK, comparing the responses and their effects in England, Scotland, Wales and Northern Ireland, providing perspectives on effects of policy changes designed to reduce risk of infection as a result of COVID-19, specifically on volunteer involvement of and for older adults, and understand, from the perspectives of volunteer managers, how COVID-19 restrictions had impacted older people’s volunteering and situating this within statutory public health policies.The study uses a crit...
Source: Quality in Ageing and Older Adults - March 29, 2024 Category: Geriatrics Authors: Jurgen Grotz Lindsay Armstrong Heather Edwards Aileen Jones Michael Locke Laurel Smith Ewen Speed Linda Birt Source Type: research

Longitudinal observational cohort study: Speech for Intelligent cognition change tracking and DEtection of Alzheimers Disease (SIDE-AD)
Introduction There is emerging evidence that speech may be a potential indicator and manifestation of early Alzheimer’s disease (AD) pathology. Therefore, the University of Edinburgh and Sony Research have partnered to create the Speech for Intelligent cognition change tracking and DEtection of Alzheimer’s Disease (SIDE-AD) study, which aims to develop digital speech-based biomarkers for use in neurodegenerative disease. Methods and analysis SIDE-AD is an observational longitudinal study, collecting samples of spontaneous speech. Participants are recruited from existing cohort studies as well as from the Natio...
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Saunders, S., Haider, F., Ritchie, C. W., Muniz Terrera, G., Luz, S. Tags: Open access, Neurology Source Type: research

Increase in invasive Streptococcus pyogenes M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
Group AStreptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Iceland. (Source: Eurosurveillance)
Source: Eurosurveillance - March 28, 2024 Category: Infectious Diseases Authors: Stephen B Beres, Randall J Olsen, S Wesley Long, Ross Langley, Thomas Williams, Helga Erlendsdottir, Andrew Smith, Karl G Kristinsson and James M Musser Source Type: research

Ongoing burden and recent trends in severe hospitalised hypoglycaemia events in people with type 1 and type 2 diabetes in Scotland: A nationwide cohort study 2016 –2022
We examined severe hospitalised hypoglycaemia (SHH) rates in people with type 1 and type 2 diabetes in Scotland during 2016 –2022, stratifying by sociodemographics. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: William Berthon, Stuart J. McGurnaghan, Luke A.K. Blackbourn, Joseph Mellor, Fraser W. Gibb, Simon Heller, Brian Kennon, Rory J. McCrimmon, Sam Philip, Naveed Sattar, Paul M. McKeigue, Helen M. Colhoun, Scottish Diabetes Research Network Epidemiology Grou Source Type: research

Analysis of per- and polyfluoroalkyl substances (PFAS) in raw materials intended for the production of paper-based food contact materials – evaluating LC-MS/MS versus total fluorine and extractable organic fluorine
. (Source: Food Additives and Contaminants Part A)
Source: Food Additives and Contaminants Part A - March 26, 2024 Category: Food Science Authors: Milica Jovanovi ćViktoria MüllerJörg FeldmannErich Leitnera Institute of Analytical Chemistry and Food Chemistry, TU Graz, Austriab The James Hutton Institute, Aberdeen, Scotland, UKc TESLA – Analytical Chemistry, Institute for Chemistry, University Source Type: research

Did the first description of patients with polymyalgia rheumatica take place in Scotland or in Denmark?
Reumatismo. 2024 Mar 22;76(1). doi: 10.4081/reumatismo.2024.1673.ABSTRACTThe first description of polymyalgia rheumatica (PMR) is generally attributed to Dr. Bruce. In an 1888 article entitled Senile rheumatic gout, he described five male patients aged from 60 to 74 years whom he had visited at the Strathpeffer spa in Scotland. In 1945, Dr. Holst and Dr. Johansen reported on five female patients examined over several months at the Medical Department of Roskilde County Hospital in Denmark. These patients suffered from hip, upper arms, and neck pain associated with elevated ESR and constitutional manifestations such as low-g...
Source: Reumatismo - March 25, 2024 Category: Rheumatology Authors: C Manzo M Isetta A Castagna Source Type: research