Epidemiology of Robin sequence: geographical variation in the UK/Ireland
Introduction Pierre Robin sequence (PRS) is a rare congenital malformation sequence characterised by micrognathia, glossoptosis and upper airway obstruction, often in association with a wide U-shaped cleft palate.1 The aetiology of non-syndromic PRS (nsPRS) remains uncertain; however, non-isolated PRS can present as part of a wider syndromic diagnosis1 (syndromic PRS (sPRS)). PRS is reported to have a prevalence of ~1/8000 to 1/14000 live births.1 2 A recent study by Wright et al (ADC), which used dual-source case ascertainment and active surveillance methods, estimated a PRS prevalence of 1:5246 live births.1 This is sign...
Source: Archives of Disease in Childhood - February 19, 2024 Category: Pediatrics Authors: Atton, G., Baralle, D. Tags: Editorial Source Type: research
Social Distance Warriors Should Not Be Regarded as Moral Exemplars in a Pandemic Nor as Paragons of Politeness: A Response to Shaw
This article shows that his claims are contestable. It suggests that his own behaviour was no better than Jack’s. (Source: Journal of Bioethical Inquiry)
Source: Journal of Bioethical Inquiry - February 19, 2024 Category: Medical Ethics Source Type: research
An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study
Conclusions/interpretationUsing machine learning approaches, we show that insulin requirement risk can be modestly well predicted by predominantly clinical variables. Inclusion of molecular markers improves the prognostic performance beyond that of clinical variables by up to 5%. Such prognostic models could be useful for identifying people with diabetes at high risk of progressing quickly to treatment intensification.Data availabilitySummary statistics of lipidomic, proteomic and metabolomic data are available from a Shiny dashboard athttps://rhapdata-app.vital-it.ch.Graphical Abstract (Source: Diabetologia)
Source: Diabetologia - February 19, 2024 Category: Endocrinology Source Type: research
The impact of the cost of living crisis and food insecurity on food purchasing behaviours and food preparation practices in people living with obesity
Appetite. 2024 Feb 15:107255. doi: 10.1016/j.appet.2024.107255. Online ahead of print.ABSTRACTLower income households are at greater risk of food insecurity and poor diet quality than higher income households. In high-income countries, food insecurity is associated with high levels of obesity, and in the UK specifically, the cost of living crisis (i.e., where the cost of everyday essentials has increased quicker than wages) is likely to have exacerbated existing dietary inequalities. There is currently a lack of understanding of the impact of the current UK cost of living crisis on food purchasing and food preparation prac...
Source: Appetite - February 17, 2024 Category: Nutrition Authors: Rebecca A Stone Adrian Brown Flora Douglas Mark A Green Emma Hunter Marta Lonnie Alexandra M Johnstone Charlotte A Hardman FIO-Food Team Source Type: research
Higher air pollution exposure in early life is associated with worse health among older adults: A 72-year follow-up study from Scotland
This study explored the relationship between fine particle (PM2.5) exposure at age 3 and limiting long-term illness (LLTI) at ages 55, 65 and 75 using data from the Scottish Longitudinal Study Birth Cohort 1936, a representative administrative cohort study. We found that early life PM2.5 exposure was associated with higher odds of LLTI in mid-to-late adulthood (OR = 1.10, 95% CI: 1.06, 1.14 per 10 μg m-3 increment) among the 2085 participants, with stronger associations among those growing up in disadvantaged families. Path analyses suggested that 15-21% of the association between early life PM2.5 concentrations and LLTI ...
Source: Health and Place - February 17, 2024 Category: Environmental Health Authors: Gerg ő Baranyi Lee Williamson Zhiqiang Feng Edward Carnell Massimo Vieno Chris Dibben Source Type: research
The impact of the cost of living crisis and food insecurity on food purchasing behaviours and food preparation practices in people living with obesity
Appetite. 2024 Feb 15:107255. doi: 10.1016/j.appet.2024.107255. Online ahead of print.ABSTRACTLower income households are at greater risk of food insecurity and poor diet quality than higher income households. In high-income countries, food insecurity is associated with high levels of obesity, and in the UK specifically, the cost of living crisis (i.e., where the cost of everyday essentials has increased quicker than wages) is likely to have exacerbated existing dietary inequalities. There is currently a lack of understanding of the impact of the current UK cost of living crisis on food purchasing and food preparation prac...
Source: Appetite - February 17, 2024 Category: Nutrition Authors: Rebecca A Stone Adrian Brown Flora Douglas Mark A Green Emma Hunter Marta Lonnie Alexandra M Johnstone Charlotte A Hardman FIO-Food Team Source Type: research
Higher air pollution exposure in early life is associated with worse health among older adults: A 72-year follow-up study from Scotland
This study explored the relationship between fine particle (PM2.5) exposure at age 3 and limiting long-term illness (LLTI) at ages 55, 65 and 75 using data from the Scottish Longitudinal Study Birth Cohort 1936, a representative administrative cohort study. We found that early life PM2.5 exposure was associated with higher odds of LLTI in mid-to-late adulthood (OR = 1.10, 95% CI: 1.06, 1.14 per 10 μg m-3 increment) among the 2085 participants, with stronger associations among those growing up in disadvantaged families. Path analyses suggested that 15-21% of the association between early life PM2.5 concentrations and LLTI ...
Source: Health and Place - February 17, 2024 Category: Environmental Health Authors: Gerg ő Baranyi Lee Williamson Zhiqiang Feng Edward Carnell Massimo Vieno Chris Dibben Source Type: research
Higher air pollution exposure in early life is associated with worse health among older adults: A 72-year follow-up study from Scotland
This study explored the relationship between fine particle (PM2.5) exposure at age 3 and limiting long-term illness (LLTI) at ages 55, 65 and 75 using data from the Scottish Longitudinal Study Birth Cohort 1936, a representative administrative cohort study. We found that early life PM2.5 exposure was associated with higher odds of LLTI in mid-to-late adulthood (OR = 1.10, 95% CI: 1.06, 1.14 per 10 μg m-3 increment) among the 2085 participants, with stronger associations among those growing up in disadvantaged families. Path analyses suggested that 15-21% of the association between early life PM2.5 concentrations and LLTI ...
Source: Health and Place - February 17, 2024 Category: Environmental Health Authors: Gerg ő Baranyi Lee Williamson Zhiqiang Feng Edward Carnell Massimo Vieno Chris Dibben Source Type: research
Higher air pollution exposure in early life is associated with worse health among older adults: A 72-year follow-up study from Scotland
This study explored the relationship between fine particle (PM2.5) exposure at age 3 and limiting long-term illness (LLTI) at ages 55, 65 and 75 using data from the Scottish Longitudinal Study Birth Cohort 1936, a representative administrative cohort study. We found that early life PM2.5 exposure was associated with higher odds of LLTI in mid-to-late adulthood (OR = 1.10, 95% CI: 1.06, 1.14 per 10 μg m-3 increment) among the 2085 participants, with stronger associations among those growing up in disadvantaged families. Path analyses suggested that 15-21% of the association between early life PM2.5 concentrations and LLTI ...
Source: Health and Place - February 17, 2024 Category: Environmental Health Authors: Gerg ő Baranyi Lee Williamson Zhiqiang Feng Edward Carnell Massimo Vieno Chris Dibben Source Type: research
Rare Compression Syndrome of the Median Nerve due to a Supracondylar Humeral Process and a Ligament of Struthers
Handchir Mikrochir Plast Chir. 2024 Feb 15. doi: 10.1055/a-2234-4636. Online ahead of print.ABSTRACTINTRODUCTION: A supracondylar process is a bony spur on the distal anteromedial surface of the humerus, and it is considered an anatomical variant with a prevalence of 0.4-2.7% according to anatomical studies. In almost all cases, it is associated with a fibrous, sometimes ossified ligament, which extends from the supracondylar process to the medial epicondyle. This ligament is known in the literature as the ligament of Struthers, named after the Scottish anatomist who first described it in detail in 1854. In rare cases, the...
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - February 15, 2024 Category: Cosmetic Surgery Authors: Davide Tosin Gregor Antoniadis Christian Rainer Wirtz Maria Teresa Pedro Source Type: research
