Risk Factors for Digital Ulcers in Systemic SclerosisRisk Factors for Digital Ulcers in Systemic Sclerosis
Physicians should use more aggressive therapy for patients with systemic sclerosis who are at high risk for digital ulcers, according to researchers who identified a predictor for this complication. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 22, 2016 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Fight PAH in Systemic Sclerosis With Combination TherapyFight PAH in Systemic Sclerosis With Combination Therapy
Response is better when the initial treatment of pulmonary artery hypertension (PAH) in patients with systemic sclerosis is combination therapy, an analysis from the AMBITION trial has shown. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 21, 2016 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Organ Complications Can Hit Early in Systemic SclerosisOrgan Complications Can Hit Early in Systemic Sclerosis
For most people with systemic sclerosis, pulmonary, heart, and other complications start early and ramp up quickly, according to an analysis of nearly 10,000 EUSTAR patients. Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - February 19, 2016 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news

Systemic Sclerosis World Congress (SSWC) 2016Systemic Sclerosis World Congress (SSWC) 2016
Read clinically focused news coverage of key developments from SSWC 2016. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - February 17, 2016 Category: Rheumatology Tags: Conference Coverage Source Type: news

Systemic Sclerosis World Congress Sold OutSystemic Sclerosis World Congress Sold Out
Major trial findings and uncommon manifestations of scleroderma will be highlighted at the Systemic Sclerosis World Congress, which has had to turn away prospective attendees. Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - February 17, 2016 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news

Cardiac Risks High in Systemic Sclerosis (CME/CE)
(MedPage Today) -- Equivalent to the risks in rheumatoid arthritis (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 15, 2016 Category: Cardiology Source Type: news

Lung Ailment in Systemic Sclerosis More Aggressive in Men (CME/CE)
(MedPage Today) -- But survival the same as in women (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - February 7, 2016 Category: Primary Care Source Type: news

Assessing the Inhibitory Activity of Oligonucleotides on TLR7 Sensing
Aberrant sensing of self-nucleic acids by Toll-like receptor (TLR) 7, 8, or 9 is associated with several autoimmune disorders, including systemic lupus erythematosus (SLE), rheumatoid arthritis, psoriasis, or systemic sclerosis. In recent years, several classes of synthetic oligonucleotides have been shown to antagonize sensing of immunostimulatory nucleic acids by TLR7/8/9, indicating that these molecules could have therapeutic applications in such autoimmune diseases. Conversely, synthetic oligonucleotides used in therapeutic technologies such as antisense and microRNA inhibitors also have the potential to inhibit TLR7/8...
Source: Springer protocols feed by Immunology - January 7, 2016 Category: Allergy & Immunology Source Type: news

Epigenetics in the Pathogenesis of Systemic SclerosisEpigenetics in the Pathogenesis of Systemic Sclerosis
This review examines the significant role of epigenetic modifications in the pathogenesis of systemic sclerosis. Rheumatology (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 16, 2015 Category: Pathology Tags: Rheumatology Journal Article Source Type: news

Boehringer begins patient enrolment in nintedanib trial to treat SSc and SSc-ILD
Germany-based Boehringer Ingelheim has begun enrolling patients in a global Phase III trial (Senscis) of nintedanib, a potential treatment for systemic sclerosis (SSc). (Source: Drug Development Technology)
Source: Drug Development Technology - December 9, 2015 Category: Pharmaceuticals Source Type: news

Chemotherapy Isn't Only for Cancer Patients
When you hear the word chemotherapy what immediately comes to mind? Cancer. Bald. Nausea. Vomiting. Infusions. Sterility. Bone Pain? Upon hearing that word, most people jump to the same conclusions, with the same general consensus on how chemo works, who receives it, and what side effects it has on the body. The truth is chemotherapy isn't only for cancer patients, and affects each patient differently depending on how it is used. Chemotherapy is a widely used class of drugs to treat many different disorders including, but not limited to: cancers, blood disorders, and a plethora of autoimmune diseases. Similarly it can be...
Source: Healthy Living - The Huffington Post - December 8, 2015 Category: Consumer Health News Source Type: news

New Phase III study of nintedanib in people with systemic sclerosis and lung fibrosis
(Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - December 7, 2015 Category: Research Source Type: news

New Phase III Study of Nintedanib in People with Systemic Sclerosis and Lung Fibrosis Launched
• First person enrolled in the SENSCIS™ (Safety and Efficacy of Nintedanib in Systemic SClerosIS)   study investigating nintedanib in people with systemic sclerosis who also develop interstitial lung   disease (SSc-ILD) • Phase III trial is now open for recruitment • After demonstrating that nintedanib slows disease progression in idiopathic pulmonary fibrosis,   Boehringer Ingelheim is expanding its research with nintedanib into other serious fibrotic lung   conditions that arise in association with rare diseases like systemic sclerosis (Source: Boehringer Ingelheim Press Releases)
Source: Boehringer Ingelheim Press Releases - December 7, 2015 Category: Research Source Type: news

Digital Ulcers Predict Systemic Sclerosis Complications (CME/CE)
(MedPage Today) -- Chronic ulcers associated with high rates of gangrene, amputation (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - December 3, 2015 Category: Primary Care Source Type: news

Genetics of Systemic SclerosisGenetics of Systemic Sclerosis
This review summarizes recent advances in systemic sclerosis genetics. Current Opinion in Rheumatology (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - December 2, 2015 Category: Orthopaedics Tags: Rheumatology Journal Article Source Type: news