A multi-institutional retrospective study of 340 cases of sinonasal malignant tumor
Sinonasal malignant tumors (SNMT) are relatively rare among head and neck malignant tumors. Most are squamous cell carcinomas, and malignant melanomas, olfactory neuroblastomas, adenoid cystic carcinomas, sarcomas, and others also occur. The most common primary site of nasal sinus squamous cell carcinoma is the maxillary sinus.In recent years, a decrease in incidence of maxillary sinus squamous cell carcinoma (MSSCC) has been reported along with a decrease in the incidence of sinusitis. MSSCC is treated with a combination of surgery, radiation, and chemotherapy. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - May 27, 2023 Category: ENT & OMF Authors: Takuya Tsuji, Ryo Asato, Shinpei Kada, Morimasa Kitamura, Hisanobu Tamaki, Masanobu Mizuta, Shinzo Tanaka, Yoshiki Watanabe, Ryusuke Hori, Tsuyoshi Kojima, Shogo Shinohara, Shinji Takebayashi, Toshiki Maetani, Hiroyuki Harada, Yoshiharu Kitani, Yohei Kuma Tags: Original Article Source Type: research

Clinicopathological Characteristics and Mutational Landscape of < em > APC < /em > , < em > HOXB13, < /em > and < em > KRAS < /em > among Rwandan Patients with Colorectal Cancer
In conclusion, here we contribute new genetic variation data and provide clinicopathological information pertinent to CRC in Rwanda.PMID:37232746 | DOI:10.3390/cimb45050277 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - May 26, 2023 Category: Molecular Biology Authors: Felix Manirakiza Eric Rutaganda Hidetaka Yamada Yuji Iwashita Belson Rugwizangoga Benoit Seminega Vincent Dusabejambo Gervais Ntakirutimana Deogratias Ruhangaza Annette Uwineza Kazuya Shinmura Haruhiko Sugimura Source Type: research

Surgical Management of Retroperitoneal Sarcoma
Curr Oncol. 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349.ABSTRACTSurgery is the cornerstone of treatment for retroperitoneal sarcoma (RPS). Surgery should be performed by a surgical oncologist with sub-specialization in this disease and in the context of a multidisciplinary team of sarcoma specialists. For primary RPS, the goal of surgery is to achieve the complete en bloc resection of the tumor along with involved organs and structures to maximize the clearance of the disease. The extent of resection also needs to consider the risk of complications. Unfortunately, the overarching challenge in primary RPS tr...
Source: Current Oncology - May 26, 2023 Category: Cancer & Oncology Authors: Dana A Dominguez Sagus Sampath Mark Agulnik Yu Liang Bao Nguyen Vijay Trisal Laleh G Melstrom Aaron G Lewis Isaac Benjamin Paz Randall F Roberts William W Tseng Source Type: research

Desmoid Tumors in Familial Adenomatous Polyposis Patients: Favorable Outcomes with Multidisciplinary Management
CONCLUSIONS: The majority of DTs in FAP patients remained stable with observation or a single intervention. There were no DT-related deaths; however, 12 of 45 patients (26.7%) experienced significant tumor morbidity and required more interventions for disease control. Further studies on quality of life are required.PMID:37237094 | DOI:10.1245/s10434-023-13675-1 (Source: Ann Oncol)
Source: Ann Oncol - May 26, 2023 Category: Cancer & Oncology Authors: Eisar Al-Sukhni Joel Shapiro Harini Suraweera Kara Semotiuk Carol J Swallow Savtaj Brar Albiruni Razak Abha A Gupta Rebecca A Gladdy Source Type: research

Clinicopathological Characteristics and Mutational Landscape of < em > APC < /em > , < em > HOXB13, < /em > and < em > KRAS < /em > among Rwandan Patients with Colorectal Cancer
In conclusion, here we contribute new genetic variation data and provide clinicopathological information pertinent to CRC in Rwanda.PMID:37232746 | PMC:PMC10217012 | DOI:10.3390/cimb45050277 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - May 26, 2023 Category: Molecular Biology Authors: Felix Manirakiza Eric Rutaganda Hidetaka Yamada Yuji Iwashita Belson Rugwizangoga Benoit Seminega Vincent Dusabejambo Gervais Ntakirutimana Deogratias Ruhangaza Annette Uwineza Kazuya Shinmura Haruhiko Sugimura Source Type: research

Surgical Management of Retroperitoneal Sarcoma
Curr Oncol. 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349.ABSTRACTSurgery is the cornerstone of treatment for retroperitoneal sarcoma (RPS). Surgery should be performed by a surgical oncologist with sub-specialization in this disease and in the context of a multidisciplinary team of sarcoma specialists. For primary RPS, the goal of surgery is to achieve the complete en bloc resection of the tumor along with involved organs and structures to maximize the clearance of the disease. The extent of resection also needs to consider the risk of complications. Unfortunately, the overarching challenge in primary RPS tr...
Source: Current Oncology - May 26, 2023 Category: Cancer & Oncology Authors: Dana A Dominguez Sagus Sampath Mark Agulnik Yu Liang Bao Nguyen Vijay Trisal Laleh G Melstrom Aaron G Lewis Isaac Benjamin Paz Randall F Roberts William W Tseng Source Type: research

Desmoid Tumors in Familial Adenomatous Polyposis Patients: Favorable Outcomes with Multidisciplinary Management
CONCLUSIONS: The majority of DTs in FAP patients remained stable with observation or a single intervention. There were no DT-related deaths; however, 12 of 45 patients (26.7%) experienced significant tumor morbidity and required more interventions for disease control. Further studies on quality of life are required.PMID:37237094 | DOI:10.1245/s10434-023-13675-1 (Source: Ann Oncol)
Source: Ann Oncol - May 26, 2023 Category: Cancer & Oncology Authors: Eisar Al-Sukhni Joel Shapiro Harini Suraweera Kara Semotiuk Carol J Swallow Savtaj Brar Albiruni Razak Abha A Gupta Rebecca A Gladdy Source Type: research

Clinicopathological Characteristics and Mutational Landscape of < em > APC < /em > , < em > HOXB13, < /em > and < em > KRAS < /em > among Rwandan Patients with Colorectal Cancer
In conclusion, here we contribute new genetic variation data and provide clinicopathological information pertinent to CRC in Rwanda.PMID:37232746 | PMC:PMC10217012 | DOI:10.3390/cimb45050277 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - May 26, 2023 Category: Molecular Biology Authors: Felix Manirakiza Eric Rutaganda Hidetaka Yamada Yuji Iwashita Belson Rugwizangoga Benoit Seminega Vincent Dusabejambo Gervais Ntakirutimana Deogratias Ruhangaza Annette Uwineza Kazuya Shinmura Haruhiko Sugimura Source Type: research

Surgical Management of Retroperitoneal Sarcoma
Curr Oncol. 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349.ABSTRACTSurgery is the cornerstone of treatment for retroperitoneal sarcoma (RPS). Surgery should be performed by a surgical oncologist with sub-specialization in this disease and in the context of a multidisciplinary team of sarcoma specialists. For primary RPS, the goal of surgery is to achieve the complete en bloc resection of the tumor along with involved organs and structures to maximize the clearance of the disease. The extent of resection also needs to consider the risk of complications. Unfortunately, the overarching challenge in primary RPS tr...
Source: Current Oncology - May 26, 2023 Category: Cancer & Oncology Authors: Dana A Dominguez Sagus Sampath Mark Agulnik Yu Liang Bao Nguyen Vijay Trisal Laleh G Melstrom Aaron G Lewis Isaac Benjamin Paz Randall F Roberts William W Tseng Source Type: research

Clinicopathological Characteristics and Mutational Landscape of < em > APC < /em > , < em > HOXB13, < /em > and < em > KRAS < /em > among Rwandan Patients with Colorectal Cancer
In conclusion, here we contribute new genetic variation data and provide clinicopathological information pertinent to CRC in Rwanda.PMID:37232746 | PMC:PMC10217012 | DOI:10.3390/cimb45050277 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - May 26, 2023 Category: Molecular Biology Authors: Felix Manirakiza Eric Rutaganda Hidetaka Yamada Yuji Iwashita Belson Rugwizangoga Benoit Seminega Vincent Dusabejambo Gervais Ntakirutimana Deogratias Ruhangaza Annette Uwineza Kazuya Shinmura Haruhiko Sugimura Source Type: research

Surgical Management of Retroperitoneal Sarcoma
Curr Oncol. 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349.ABSTRACTSurgery is the cornerstone of treatment for retroperitoneal sarcoma (RPS). Surgery should be performed by a surgical oncologist with sub-specialization in this disease and in the context of a multidisciplinary team of sarcoma specialists. For primary RPS, the goal of surgery is to achieve the complete en bloc resection of the tumor along with involved organs and structures to maximize the clearance of the disease. The extent of resection also needs to consider the risk of complications. Unfortunately, the overarching challenge in primary RPS tr...
Source: Current Oncology - May 26, 2023 Category: Cancer & Oncology Authors: Dana A Dominguez Sagus Sampath Mark Agulnik Yu Liang Bao Nguyen Vijay Trisal Laleh G Melstrom Aaron G Lewis Isaac Benjamin Paz Randall F Roberts William W Tseng Source Type: research

Clinicopathological Characteristics and Mutational Landscape of < em > APC < /em > , < em > HOXB13, < /em > and < em > KRAS < /em > among Rwandan Patients with Colorectal Cancer
In conclusion, here we contribute new genetic variation data and provide clinicopathological information pertinent to CRC in Rwanda.PMID:37232746 | PMC:PMC10217012 | DOI:10.3390/cimb45050277 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - May 26, 2023 Category: Molecular Biology Authors: Felix Manirakiza Eric Rutaganda Hidetaka Yamada Yuji Iwashita Belson Rugwizangoga Benoit Seminega Vincent Dusabejambo Gervais Ntakirutimana Deogratias Ruhangaza Annette Uwineza Kazuya Shinmura Haruhiko Sugimura Source Type: research

Surgical Management of Retroperitoneal Sarcoma
Curr Oncol. 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349.ABSTRACTSurgery is the cornerstone of treatment for retroperitoneal sarcoma (RPS). Surgery should be performed by a surgical oncologist with sub-specialization in this disease and in the context of a multidisciplinary team of sarcoma specialists. For primary RPS, the goal of surgery is to achieve the complete en bloc resection of the tumor along with involved organs and structures to maximize the clearance of the disease. The extent of resection also needs to consider the risk of complications. Unfortunately, the overarching challenge in primary RPS tr...
Source: Current Oncology - May 26, 2023 Category: Cancer & Oncology Authors: Dana A Dominguez Sagus Sampath Mark Agulnik Yu Liang Bao Nguyen Vijay Trisal Laleh G Melstrom Aaron G Lewis Isaac Benjamin Paz Randall F Roberts William W Tseng Source Type: research

Clinicopathological Characteristics and Mutational Landscape of < em > APC < /em > , < em > HOXB13, < /em > and < em > KRAS < /em > among Rwandan Patients with Colorectal Cancer
In conclusion, here we contribute new genetic variation data and provide clinicopathological information pertinent to CRC in Rwanda.PMID:37232746 | PMC:PMC10217012 | DOI:10.3390/cimb45050277 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - May 26, 2023 Category: Molecular Biology Authors: Felix Manirakiza Eric Rutaganda Hidetaka Yamada Yuji Iwashita Belson Rugwizangoga Benoit Seminega Vincent Dusabejambo Gervais Ntakirutimana Deogratias Ruhangaza Annette Uwineza Kazuya Shinmura Haruhiko Sugimura Source Type: research

Surgical Management of Retroperitoneal Sarcoma
Curr Oncol. 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349.ABSTRACTSurgery is the cornerstone of treatment for retroperitoneal sarcoma (RPS). Surgery should be performed by a surgical oncologist with sub-specialization in this disease and in the context of a multidisciplinary team of sarcoma specialists. For primary RPS, the goal of surgery is to achieve the complete en bloc resection of the tumor along with involved organs and structures to maximize the clearance of the disease. The extent of resection also needs to consider the risk of complications. Unfortunately, the overarching challenge in primary RPS tr...
Source: Current Oncology - May 26, 2023 Category: Cancer & Oncology Authors: Dana A Dominguez Sagus Sampath Mark Agulnik Yu Liang Bao Nguyen Vijay Trisal Laleh G Melstrom Aaron G Lewis Isaac Benjamin Paz Randall F Roberts William W Tseng Source Type: research