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Top stories in health and medicine, June 30, 2014
From MedPage Today: FDA Finally OKs Inhaled Insulin. After several denials, the FDA announced Friday that it had approved inhaled insulin (Afrezza) to be used for improving glycemic control in adult patients with diabetes. ADHD Meds Tied to Cardio Risk. Danish children taking stimulant drugs for attention deficit-hyperactivity disorder (ADHD) had roughly double the risk for cardiovascular problems compared with other ADHD kids, a large registry study found, although the absolute incidence was still very low. Diabetes Drug Denials Bad for Care? Endocrinologists are concerned that recent decisions by insurers to stop cover...
Source: Kevin, M.D. - Medical Weblog - June 30, 2014 Category: Journals (General) Authors: Tags: News ADHD Diabetes Endocrinology Heart Source Type: blogs

Streamlining the process to approve new drugs can save lives
My heart sinks each time I see the subject line in this too common email I receive in my medical practice: “Sad news: Matthew was fine when he went to bed last night but his mother found him dead in bed this morning.” Matthew (not his real name) had epilepsy with seizures that persisted despite use of currently available antiseizure medications. Continue reading ... Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how.
Source: Kevin, M.D. - Medical Weblog - July 14, 2014 Category: Journals (General) Authors: Tags: Meds Medications Neurology Source Type: blogs

Top stories in health and medicine, July 24, 2014
From MedPage Today: Weight Watchers Tops in Efficacy Vs. Cost. Among the most popular diet programs and drugs, Weight Watchers trims the most bulge for the buck, according to a new cost-effectiveness analysis. Probiotics: Moderate Impact on BP? Probiotics cut blood pressure by roughly 4 mm Hg systolic and 2 mm Hg diastolic on average across clinical trials. Clinton to AIDS Conference: Step It Up The destruction of Malaysia Airlines flight MH17 with six AIDS researchers and activists aboard is a “stark reflection” of the negative side of an interdependent world, former President Bill Clinton said here. FDA Iss...
Source: Kevin, M.D. - Medical Weblog - July 24, 2014 Category: Journals (General) Authors: Tags: News Heart Infectious disease Obesity Source Type: blogs

Top stories in health and medicine, August 6, 2014
From MedPage Today: Advocacy Groups Take Obesity Naysayers to Task. Two obesity advocacy groups took to the pages of the Archives of Internal Medicine this week to castigate a report that questioned the legitimacy of obesity as a disease and cast an unfavorable light on new weight-loss drugs. Shoulder Pain: PT Works Well and Costs Less Than Shots. Patients with shoulder pain receiving corticosteroid injections (CSI) versus manual physical therapy (MPT) had the same amount of symptom improvement, but the corticosteroid group used more healthcare resources. OSA Exam Best for ‘Unexplained Daytime Sleepiness’. Sl...
Source: Kevin, M.D. - Medical Weblog - August 6, 2014 Category: Journals (General) Authors: Tags: News Infectious disease orthopedics Pulmonology Source Type: blogs

New PubMed Tutorial: Searching Drugs or Chemicals in PubMed
http://www.nlm.nih.gov/pubs/techbull/ja14/brief/ja14_pm_tutorial_drugs.html
Source: NN/LM Middle Atlantic Region Blog - August 11, 2014 Category: Databases & Libraries Authors: mjharvey Tags: Education News from NLM/NIH Technology Technology and Libraries Source Type: news

Top stories in health and medicine, August 14, 2014
From MedPage Today: Beyond Asbestos: Autoimmunity, Pollution, and Particles. Recently, I wrote an article about some interesting research being done by Jean Pfau, PhD, of Idaho State University suggesting that workers who had been exposed to asbestos at the now-shuttered Zonolite mine in Montana were developing an as-yet undescribed autoimmune condition characterized by severe pain and restricted breathing. High-Dose Aspirin After MI Still Common. Many patients with myocardial infarction (MI) were discharged from U.S. hospitals on high-dose aspirin, even if they were at high risk for bleeding. WHO Ethics Panel Affirms Us...
Source: Kevin, M.D. - Medical Weblog - August 14, 2014 Category: Journals (General) Authors: Tags: News Heart Infectious disease Source Type: blogs

Top stories in health and medicine, August 15, 2014
From MedPage Today: NSAIDs May Slow Breast Ca in Obese Women. Obese women with estrogen receptor-positive breast cancer had a 52% lower risk of recurrence when they regularly used aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Mix of Kudos and Caution for Fecal DNA Test. Approval and imminent Medicare coverage of a DNA screening test for colorectal cancer generally received props from clinicians and researchers, who nonetheless cited continued patient aversion as the biggest obstacle to screening. Hospitals Seek To Help With ACA Premiums. Low-income consumers struggling to pay their premiums may soon be ...
Source: Kevin, M.D. - Medical Weblog - August 15, 2014 Category: Journals (General) Authors: Tags: News Cancer GI Source Type: blogs

Top stories in health and medicine, August 26, 2014
From MedPage Today: Adrenaline: The Best and Worst of Drugs. Despite it being the first-line adrenergic drug for patients with cardiac arrest, few studies in humans have assessed epinephrine’s effectiveness. Increase E-Cig Regulation, Says AHA. The federal government should ban the sale of e-cigarettes to minors just as it does cigarettes and smokeless tobacco products, wrote researchers in a policy statement issued by the American Heart Association. Physician Recruiters Chasing Primary Care Clinicians. Primary care continues to be in high demand with in-house physician recruiter jobs, and primary care job placemen...
Source: Kevin, M.D. - Medical Weblog - August 26, 2014 Category: Journals (General) Authors: Tags: News Diabetes Endocrinology Heart Source Type: blogs

Top stories in health and medicine, August 27, 2014
From MedPage Today: ‘Sleep Drunkenness’ Common, But Rarely Unexplained. So-called confusional arousals — awakenings without coming fully aware — were reported in the past year by some 15% of respondents in a population-based survey, with nearly all such episodes associated with mental disorders or drugs known to affect sleep. The Siren Call of E-Cigarettes. Many of the e-cigarette recommendations made by the American Heart Association involve initiatives aimed at preventing youth access to the product. Controversy Aside, New Lipid Guidelines Prove Superior. The contentious American Heart Associati...
Source: Kevin, M.D. - Medical Weblog - August 27, 2014 Category: Journals (General) Authors: Tags: News Heart Pediatrics Source Type: blogs

Top stories in health and medicine, September 11, 2014
From MedPage Today: Azithromycin Linked to Belly Blockage in Infants. Infants who received azithromycin (Zithromax) in the early days of life were at an increased risk for developing infantile hypertrophic pyloric stenosis (IHPS). Singulair Doesn’t Ease Wheeze in Most Kids. Intermittent montelukast (Singulair) didn’t alleviate wheezing in children, except possibly for those with a specific genetic mutation. Single-Pill HIV Therapy Proves Less Toxic. An investigational single-pill regimen for HIV — the first to be based on a protease inhibitor — was less toxic than a similar regimen using separate ...
Source: Kevin, M.D. - Medical Weblog - September 11, 2014 Category: Journals (General) Authors: Tags: News Infectious disease Pulmonology Source Type: blogs

Top stories in health and medicine, September 10, 2014
From MedPage Today: Bone Drugs Work; Effects and Risks Vary. Treatments for osteoporosis vary widely in terms of risk-benefit profile. Red Carpet Paves Way to Research $$$. Viewers of Stand Up To Cancer’s (SU2C) fourth 1-hour live prime-time commercial-free program — telecast over more than 30 broadcast and cable networks Friday night — pledged more than $109 million, with about $82 million slated for translational cancer research projects in the U.S. and about $27 million for Canadian researchers. Polypills on FDA Docket: One Pill Panacea? Will fixed-dose polypills safely and effectively reduce the ris...
Source: Kevin, M.D. - Medical Weblog - September 10, 2014 Category: Journals (General) Authors: Tags: News Endocrinology Infectious disease Source Type: blogs

Top stories in health and medicine, September 19, 2014
From MedPage Today: Ebola Response: Fighting the Last Outbreak? The dramatic U.S. commitment of 3,000 military personnel is arguably the biggest contribution yet to the fight against the West Africa Ebola outbreak. Microbleeds May Up Afib Mortality. The presence of cerebral microbleeds was associated with an increased risk of death from both hemorrhagic and ischemic stroke in patients with atrial fibrillation. EHRs Don’t Save Money or Time, Docs Say. Three-fourths of U.S. physicians who use electronic health records (EHRs) said they aren’t cost-effective and don’t save time, but the majority said they s...
Source: Kevin, M.D. - Medical Weblog - September 19, 2014 Category: Journals (General) Authors: Tags: News Diabetes Endocrinology Heart Infectious disease Source Type: blogs

Top stories in health and medicine, October 6, 2014
From MedPage Today: Dallas Ebola Case a Distraction. Lost in all the brouhaha about the Dallas Ebola case is one salient fact: Thomas Eric Duncan, now reportedly in serious condition in Texas Health Presbyterian Hospital, didn’t catch the virus in the U.S. He caught it some 5,700 miles away in Liberia. RA and Cancer: Can Biologics Lower Risk? Patients with rheumatoid arthritis (RA) who were treated with tumor necrosis factor (TNF) inhibitors had lower rates of incident cancer compared with those on conventional disease-modifying anti-rheumatic drugs (DMARDs). Heroin Deaths Still Rising, CDC Says. More data from the...
Source: Kevin, M.D. - Medical Weblog - October 6, 2014 Category: Journals (General) Authors: Tags: News Cancer Infectious disease Rheumatology Source Type: blogs

Two-tiered generic drugs will lower quality of care
As we head into health insurance enrollment season, which opens in November, consumers/patients will face yet another challenge in selecting the best health plan. Sorting through policies was tough already, but now insurers are making it even harder by changing the way they will cover generic drugs. It used to be that opting for generics was a snap. Health plans usually offered three or four tiers of drugs — one for preferred brand drugs, one for non-preferred drugs, a category for the expensive specialty drugs and another for low-cost generics. The advice was to always buy generics if you could. Continue reading ......
Source: Kevin, M.D. - Medical Weblog - October 9, 2014 Category: Journals (General) Authors: Tags: Meds Medications Source Type: blogs

Top stories in health and medicine, October 13, 2014
From MedPage Today: Cashing in on Ebola. What was your reaction when you first realized that Ebola was killing thousands of people in Africa and would probably come ashore in America at some point? Sympathy? Worry? Scientific curiosity? An urge to hop the first plane to Monrovia? Ebola: Body Fluids Carry the Risk. The mantra of Ebola experts is that the disease is transmitted through direct contact with patient body fluids that contain the virus. But which fluids? And are they all equally risky? Joints Tell the Future in Scleroderma. Easily assessed clinical signs of joint and tendon involvement early in the course of sy...
Source: Kevin, M.D. - Medical Weblog - October 13, 2014 Category: Journals (General) Authors: Tags: News Infectious disease Rheumatology Source Type: blogs