A Study of BL-B01D1 + SI-B003 in Patients With Unresectable, Locally Advanced or Recurrent Metastatic HER2-negative Breast Cancer
Condition:   Locally Advanced or Recurrent Metastatic HER-2 Negative Breast Cancer Interventions:   Drug: BL-B01D1;   Drug: SI-B003 Sponsor:   Sichuan Baili Pharmaceutical Co., Ltd. Not yet recruiting
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

JAMA Oncology : Sentinel Lymph Node Biopsy vs No Axillary Procedure in Small Node-Negative Breast Cancer
Interview with Oreste Davide Gentilini, MD, author of Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial. Hosted by Jack West, MD. Related Content: Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes
Source: JAMA Specialty Journals Author Interviews - September 21, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

Ultrasound May Help Early Breast Cancer Patients Avoid SLNB
(MedPage Today) -- Omitting axillary surgery completely in early breast cancer patients with a negative preoperative axillary ultrasound resulted in similar outcomes compared with sentinel lymph node biopsy (SLNB), and did not appear to affect...
Source: MedPage Today Hematology/Oncology - September 21, 2023 Category: Hematology Source Type: news

I'm a cancer patient whose operation has been cancelled because of NHS walkouts. I think it's a scandal that doctors can strike
EXCLUSIVE: Monika Schiffer, from Bournemouth, was diagnosed with breast cancer in January and endured six rounds of chemotherapy.
Source: the Mail online | Health - September 21, 2023 Category: Consumer Health News Source Type: news

The effect of exercise on vascular health in chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials
Am J Physiol Renal Physiol. 2023 Sep 21. doi: 10.1152/ajprenal.00152.2023. Online ahead of print.ABSTRACTPatients with chronic kidney disease (CKD) are at increased risk of cardiovascular disease. This increased risk cannot be fully explained by traditional risk factors such as hypertension. Endothelial dysfunction and arterial stiffness have been suggested as factors which explain some of the increased risk, and are independently associated with important cardiovascular outcomes in CKD patients. Studies in other disease populations have shown positive effects of exercise on vascular dysfunction. The aim of this review was...
Source: Am J Physiol Renal P... - September 21, 2023 Category: Urology & Nephrology Authors: Mark D Davies Felicity Hughes Aamer Sandoo Abdulfattah Alejmi Jamie Hugo Macdonald Source Type: research

Brain-computer interface relieves chronic chemotherapy-induced peripheral neuropathy: A randomized, double-blind, placebo-controlled trial
CONCLUSIONS: BCI is a promising treatment for CIPN and may have a longer lasting effect than placebo (nonspecific BCI), which is an important consideration for long-term symptom relief. Although scientifically interesting, the ability to separate real from placebo treatment may not be as important as understanding the placebo effects differently from effects of the intervention.PLAIN LANGUAGE SUMMARY: Chemotherapy-induced nerve pain (neuropathy) can be disabling for cancer survivors; however, the way symptoms are felt depends on how the brain interprets the signals from nerves in the body. We determined that the perception...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Sarah Prinsloo Ted J Kaptchuk Dirk De Ridder Randall Lyle Eduardo Bruera Diane Novy Carlos H Barcenas Lorenzo G Cohen Source Type: research

Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients
CONCLUSION: Th22, Th17, Th1, and Th2 subsets may play an essential role in BC patients. Th22, Th17, Th1, and Th2 cells may have potential significance to be used as clinical markers in BC patients with different molecular classification. Th22 cells may have potential value in BC patients' outcomes prediction, providing clinical value.PMID:37732365 | DOI:10.1111/1759-7714.15119
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Zhiguo Peng Xinyue Dong Miao He Yajing Zhao Yujia Liu Mo Li Guosheng Li Xiuwen Wang Li Li Yu Hu Source Type: research

Topical Calcipotriol Plus Imiquimod Immunotherapy for Nonkeratinocyte Skin Cancers
In this study, we demonstrate that topical TSLP cytokine inducers-calcipotriol and retinoic acid-synergize with IMQ to activate CD4+ T-cell immunity against nonkeratinocyte cutaneous malignancies. Topical calcipotriol plus IMQ treatment reduced breast tumor growth compared with calcipotriol or IMQ alone (P < 0.0001). Calcipotriol plus IMQ-mediated tumor suppression was associated with significant infiltration of CD4+ effector T cells in the tumor microenvironment. Notably, topical calcipotriol plus IMQ immunotherapy enabled immune checkpoint blockade therapy to effectively control immunologically cold breast tumors, whi...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Marjan Azin Kenneth H Ngo Jennet Hojanazarova Shadmehr Demehri Source Type: research

Association between ultra-processed food consumption and risk of breast cancer: a systematic review and dose-response meta-analysis of observational studies
CONCLUSION: Our results indicate that higher consumption of UPF is slightly related to a higher risk of breast cancer. Further studies in particular of large prospective cohort studies are warranted to confirm these results.PMID:37731393 | PMC:PMC10507475 | DOI:10.3389/fnut.2023.1250361
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Long Shu Xiaoyan Zhang Qin Zhu Xiaoling Lv Caijuan Si Source Type: research

Traumatic sigmoid colon rupture due to breast cancer metastasis: a case report
Clin J Gastroenterol. 2023 Sep 21. doi: 10.1007/s12328-023-01859-x. Online ahead of print.ABSTRACTThe metastasis of breast cancer to the gastrointestinal tract is rare. Herein, we presented the case of an 85-year-old woman who had a history of invasive lobular carcinoma and experienced complete colon rupture due to relatively low-energy trauma. The patient underwent bilateral total mastectomy and axillary dissection following preoperative chemotherapy 6 years ago. She had a local recurrence 2 years after the surgery and underwent chemotherapy. Subsequently, the cancer metastasized to the thoracolumbar area and retroperiton...
Source: Clinical Genitourinary Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Tomonori Yoshida Munenori Ide Kazuhisa Katayama Mitsuhiro Yanai Ryo Kurosaki Hisashi Shimizu Kazuhisa Arakawa Tatsuya Miyazaki Hiroshi Saeki Ken Shirabe Source Type: research

Research Progress and New Perspectives of Anticancer Effects of Emodin
In conclusion, emodin represents a promising natural compound with potent anticancer properties, and its potential as a therapeutic agent for cancer treatment warrants further investigation. This review provides a comprehensive overview of the current research progress and new perspectives on emodin's anticancer effects, which may facilitate the development of novel therapeutic strategies for cancer treatment.PMID:37732372 | DOI:10.1142/S0192415X23500787
Source: The American Journal of Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Wu Liu Eskandar Qaed Yuelin Zhu Wenzhang Tian Yizhen Wang Le Kang Xiaodong Ma Zeyao Tang Source Type: research

Berberine induces apoptosis and arrests the cell cycle in multiple cancer cell lines
CONCLUSIONS: Berberine exhibited cytotoxic effects on multiple cancer cell lines by inducing apoptosis and cell cycle arrest. The BCL-2/BAX signaling pathway may be the common pathway underlying the anti-tumor effect of berberine. The findings support the notion that berberine is a dietary compound that can be further developed into a drug candidate for cancer treatment.PMID:37732040 | PMC:PMC10507748 | DOI:10.5114/aoms/132969
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Qian Li Hui Zhao Weimin Chen Ping Huang Source Type: research

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) in Poland: analysis of patient series and practical guidelines for breast surgeons
CONCLUSIONS: BIA-ALCL is scarce in the Polish population. In a short-term follow-up, patients' prognosis remains excellent. Due to the withdrawal of roughly textured implants from the market and the exclusion of likely the most potent etiologic factor, it might be expected that the incidence of BIA-ALCL will become even rarer.PMID:37732037 | PMC:PMC10507758 | DOI:10.5114/aoms.2020.100637
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Piotr Pluta Agnieszka Giza Ma łgorzata Kolenda Wojciech Fendler Marcin Braun Cezary Chudobi ński Justyna Cha łubińska-Fendler Micha ł Araszkiewicz Karolina Loga Lubomir Lembas Magdalena Witkowska Agnieszka Pluta Jerzy Kolasi ński Pawe ł Basta Agnie Source Type: research

Identification of a TRP channel-related risk model for predicting prognosis and therapeutic effects of patients with hepatocellular carcinoma
CONCLUSIONS: We successfully established a highly accurate prognostic model for predicting overall survival and therapeutic effects using TRP channel-related genes.PMID:37733242 | DOI:10.1007/s00432-023-05394-7
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Chong Pang Zhe Xu Jilong Han Fujun Li Hongyan Zhu Jiaqi Zhang Dong Wang Xundi Xu Source Type: research

Traumatic sigmoid colon rupture due to breast cancer metastasis: a case report
Clin J Gastroenterol. 2023 Sep 21. doi: 10.1007/s12328-023-01859-x. Online ahead of print.ABSTRACTThe metastasis of breast cancer to the gastrointestinal tract is rare. Herein, we presented the case of an 85-year-old woman who had a history of invasive lobular carcinoma and experienced complete colon rupture due to relatively low-energy trauma. The patient underwent bilateral total mastectomy and axillary dissection following preoperative chemotherapy 6 years ago. She had a local recurrence 2 years after the surgery and underwent chemotherapy. Subsequently, the cancer metastasized to the thoracolumbar area and retroperiton...
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Tomonori Yoshida Munenori Ide Kazuhisa Katayama Mitsuhiro Yanai Ryo Kurosaki Hisashi Shimizu Kazuhisa Arakawa Tatsuya Miyazaki Hiroshi Saeki Ken Shirabe Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20