Cancers, Vol. 15, Pages 4683: Vessel-Guided Mesohepatectomy for Liver Partition and Staged Major Parenchyma-Sparing Hepatectomies with Super-Selective Portal Vein Embolization or Enhanced ALPPS to Achieve R0 Resection for Colorectal Liver Metastases at the Hepatocaval Confluence
Conclusions. Vessel-guided MLP may transform the liver in a paired organ. In selected cases of multiple bilobar CRLM, to guarantee oncological radicality (R0), major PSH is feasible combining advanced surgical parenchyma sparing with liver augmentation techniques when FLR volume is insufficient.
Source: Cancers - September 22, 2023 Category: Cancer & Oncology Authors: Lucio Urbani Nicol ò Roffi Roberto Moretto Stefano Signori Riccardo Balestri Elisabetta Rossi Piero Colombatto Gabriella Licitra Chiara Leoni Rita Martinelli Daniele Anacleto Meiattini Emidio Bonistalli Beatrice Borelli Carlotta Antoniotti Gianluca Masi Tags: Article Source Type: research

Differential response of HER2-positive breast cancer to anti-HER2 therapy based on HER2 protein expression level
British Journal of Cancer, Published online: 22 September 2023; doi:10.1038/s41416-023-02426-4Differential response of HER2-positive breast cancer to anti-HER2 therapy based on HER2 protein expression level
Source: British Journal of Cancer - September 22, 2023 Category: Cancer & Oncology Authors: N. M. Atallah M. Alsaleem M. S. Toss N. P. Mongan E. Rakha Source Type: research

Quality of breast surgery care at a comprehensive cancer center and its rural affiliate hospital
Cancer centers are increasingly affiliating with rural hospitals to perform surgery. Perioperative and oncologic outcomes for cancer center surgeons operating at rural hospitals are understudied.
Source: American Journal of Surgery - September 22, 2023 Category: Surgery Authors: Elissa M. Dykes, Kelsey B. Montgomery, Gregory D. Kennedy, Helen Krontiras, Kristy Broman Tags: Original Research Article Source Type: research

Correction: α-Catenin acetylation is essential for its stability and blocks its tumor suppressor effects in breast cancer through Yap1
Cancer Gene Therapy, Published online: 22 September 2023; doi:10.1038/s41417-023-00668-1Correction: α-Catenin acetylation is essential for its stability and blocks its tumor suppressor effects in breast cancer through Yap1
Source: Cancer Gene Therapy - September 22, 2023 Category: Cancer & Oncology Authors: Yuxi Yang Shujing Li Yulin Li Linlin Lv Dongman Ye Jie Kang Tao Yu Yaming Wang Huijian Wu Source Type: research

Classification of breast lesions in ultrasound images using deep convolutional neural networks: transfer learning versus automatic architecture design
AbstractDeep convolutional neural networks (DCNNs) have demonstrated promising performance in classifying breast lesions in 2D ultrasound (US) images. Exiting approaches typically use pre-trained models based on architectures designed for natural images with transfer learning. Fewer attempts have been made to design customized architectures specifically for this purpose. This paper presents a comprehensive evaluation on transfer learning based solutions and automatically designed networks, analyzing the accuracy and robustness of different recognition models in three folds. First, we develop six different DCNN models (BNet...
Source: Medical and Biological Engineering and Computing - September 22, 2023 Category: Biomedical Engineering Source Type: research

Dose delivery reproducibility for PBS proton treatment of breast cancer patients with and without mask immobilization
In this study, we retrospecti...
Source: Radiation Oncology - September 22, 2023 Category: Cancer & Oncology Authors: Yixiu Kang, Martin Bues, Michele Y. Halyard, Lisa A. McGee, Tamara Z. Vern-Gross, William W. Wong, Sameer R. Keole, Carlos Vargas, Sarah E. James, Safia K. Ahmed, James P. Archuleta, Ana K. Ridgway, Pedro R. Lara and Mirek Fatyga Tags: Research Source Type: research

Immediate Lymphatic Reconstruction in 77 Consecutive Breast Cancer Patients: 2-year Follow-up
Conclusion ILR can significantly reduce the risk of developing BRCL in high-risk patients at 2 years of follow-up. Patients receiving adjuvant radiation therapy are more likely to develop BCRL after ILR compared with those who do not. Ongoing studies include investigation aimed at identifying patients most at risk for the development of BRCL to help target intervention as well as elucidate factors that contribute to the success of ILR. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Reconstructive Microsurgery - September 22, 2023 Category: Surgery Authors: Le, Nicole K. Weinstein, Brielle Parikh, Jeegan Coomar, Lokesh A. Wainwright, D'Arcy Liu, Langfeier Mammadova, Jamila Tavares, Tina Panetta, Nicholas J. Tags: Original Article Source Type: research

Effective and clinically relevant optimisation of cushioning stiffness to maximise the offloading capacity of diabetic footwear
People with diabetes can gradually lose the protective sensation of pain in their feet due to peripheral neuropathy. As a result, they tend to repeatedly overload and seriously injure their feet, causing the development of diabetic foot ulceration (DFU) [1]. DFU is an open wound with limited capacity for healing, it can get infected and even lead to amputation. It is estimated that worldwide there is one amputation every twenty seconds due to diabetes (85% of all lower-limb amputations) [2]. The severity of this fact becomes even more pronounced considering that eight out of ten people die within five years of having an am...
Source: Diabetes Research and Clinical Practice - September 22, 2023 Category: Endocrinology Authors: Panagiotis E. Chatzistergos, Alfred Gatt, Cynthia Formosa, Jonathan K. Sinclair, Nachiappan Chockalingam Source Type: research

Untargeted serum metabolomic profiles and breast density in young women
ConclusionOur results suggest an inverse association of branched chain amino acids with %DBV. Larger studies in diverse populations are needed.
Source: Cancer Causes and Control - September 22, 2023 Category: Cancer & Oncology Source Type: research

Unveiling the vulnerabilities of synthetic lethality in triple-negative breast cancer
AbstractTriple-negative breast cancer (TNBC) is the most invasive molecular subtype of breast cancer (BC), accounting for about nearly 15% of all BC cases reported annually. The absence of the three major BC hormone receptors, Estrogen (ER), Progesterone (PR), and Human Epidermal Growth Factor 2 (HER2) receptor, accounts for the characteristic “Triple negative” phraseology. The absence of these marked receptors makes this cancer insensitive to classical endocrine therapeutic approaches. Hence, the available treatment options remain solemnly limited to only conventional realms of chemotherapy and radiation therapy. More...
Source: Clinical and Translational Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research

Fitness 19 Releases "Tips for Staying Motivated on Your Health Journey"
This guide educates consumers on how to stay motivated while embarking on a health journey. TEMECULA, Calif., Sept. 21, 2023 /PRNewswire-PRWeb/ -- Fitness 19 has announced the release of its latest resource "Tips for Staying Motivated on Your Health Journey." This resource offers insight...
Source: PRWeb: Medical Pharmaceuticals - September 21, 2023 Category: Pharmaceuticals Source Type: news

AI is living up to its promise as a tool for radiology
For the last few years, artificial intelligence (AI) has been proving itself as an effective tool in breast cancer screening. An ever-growing list of research studies has shown that using AI in mammography can safely and efficiently reduce patient wait times while reducing the pressure on in-demand radiologists. This is significant, as early detection greatly Read more… AI is living up to its promise as a tool for radiology originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - September 21, 2023 Category: General Medicine Authors: Hoag Memorial Hospital Presbyterian Tags: Tech Radiology Source Type: blogs

Breast cancer expert shares ways to lower risk, catch cancer early
Loma Linda University Cancer Center oncologist reviews how to prevent breast cancer or find it early LOMA LINDA, Calif., Sept. 21, 2023 /PRNewswire-PRWeb/ -- A woman living in the United States today faces a one in eight chance of being diagnosed with breast cancer at some time during her...
Source: PRWeb: Medical Pharmaceuticals - September 21, 2023 Category: Pharmaceuticals Tags: FVT Source Type: news

Circulating Tumour Cells Characterization in Breast Cancer Patients
Condition:   Breast Cancer Intervention:   Device: Blood sample Sponsors:   Istituti Clinici Scientifici Maugeri SpA;   Carlo Morasso Recruiting
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

T-DXd Therapy for HER2-low Breast Cancer Patients With Brain Metastases
Conditions:   Breast Cancer;   Metastatic Breast Cancer Intervention:   Drug: Trastuzumab-Deruxtecan (T-DXd) Sponsors:   MedSIR;   Daiichi Sankyo, Inc. Not yet recruiting
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

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