This page shows you the latest news items in this category. This is page number 3.

Total 220205 results found since Jan 2013.

Nivolumab and Eribulin in HER2 Negative Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer Intervention:   Drug: Nivolumab Sponsors:   Seoul National University Hospital;   Seoul National University Bundang Hospital;   Korean Cancer Study Group (KCSG);   Eisai Korea;   Ono pharmaceutical Korea Recruiting
Source: ClinicalTrials.gov - August 20, 2019 Category: Research Source Type: clinical trials

Effects of Alternative Healthy Eating Index-Based Diet on Inflammatory Markers and Breast Density in Healthy Participants
Conditions:   Healthy Subject;   Nulliparous Interventions:   Dietary Supplement: Dietary Intervention;   Procedure: Dual X-ray Absorptiometry Sponsors:   Fred Hutchinson Cancer Research Center;   Breast Cancer Research Foundation;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - August 20, 2019 Category: Research Source Type: clinical trials

Nivolumab and Eribulin in HER2 Negative Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer Intervention:   Drug: Nivolumab Sponsors:   Seoul National University Hospital;   Seoul National University Bundang Hospital;   Korean Cancer Study Group (KCSG);   Eisai Korea;   Ono pharmaceutical Korea Recruiting
Source: ClinicalTrials.gov - August 20, 2019 Category: Research Source Type: clinical trials

Effects of Alternative Healthy Eating Index-Based Diet on Inflammatory Markers and Breast Density in Healthy Participants
Conditions:   Healthy Subject;   Nulliparous Interventions:   Dietary Supplement: Dietary Intervention;   Procedure: Dual X-ray Absorptiometry Sponsors:   Fred Hutchinson Cancer Research Center;   Breast Cancer Research Foundation;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - August 20, 2019 Category: Research Source Type: clinical trials

Nivolumab and Eribulin in HER2 Negative Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer Intervention:   Drug: Nivolumab Sponsors:   Seoul National University Hospital;   Seoul National University Bundang Hospital;   Korean Cancer Study Group (KCSG);   Eisai Korea;   Ono pharmaceutical Korea Recruiting
Source: ClinicalTrials.gov - August 20, 2019 Category: Research Source Type: clinical trials

Individualized Piano Instruction for Improving Cognition in Breast Cancer Survivors.
Abstract PURPOSE: To evaluate the use of individualized piano instruction (IPI) for improving cognition among breast cancer survivors. PARTICIPANTS & SETTING: Six participants were included in an eight-week piano program with three data collection time points at baseline, midpoint, and postintervention. Participants were recruited from the breast cancer clinic of a university cancer center in South Florida. METHODOLOGIC APPROACH: Neurocognitive, psychosocial, and self-report assessments were conducted to determine potential benefits and program feasibility, including the NIH Toolbox® Cognition B...
Source: Oncology Nursing Forum - August 20, 2019 Category: Nursing Authors: Rodriguez-Wolfe M, Anglade D, Gattamorta KA, Hurwitz WB, Pirl WF Tags: Oncol Nurs Forum Source Type: research

Anthracycline Chemotherapy-Induced Cardiotoxicity in Breast Cancer Survivors: A Systematic Review.
Abstract PROBLEM IDENTIFICATION: This review identifies specific cardiotoxicity related to anthracycline chemotherapy, specific risk factors related to increased anthracycline chemotherapy-induced cardiotoxicity, and underlying mechanisms of action of anthracycline chemotherapy-induced cardiotoxicity. LITERATURE SEARCH: PubMed®, CINAHL®, Embase®, and Web of Science were searched in May 2018 using keywords related to heart diseases, anthracycline chemotherapy, and breast cancer. DATA EVALUATION: Data were extracted, and study quality was assessed according to PRISMA (Preferred Reporting Items for Syste...
Source: Oncology Nursing Forum - August 20, 2019 Category: Nursing Authors: Lin KJ, Lengacher CA Tags: Oncol Nurs Forum Source Type: research

Guidelines say more women may need breast cancer gene test
New US guidelines say more women may benefit from gene testing for hereditary breast or ovarian cancer
Source: ABC News: Health - August 20, 2019 Category: Consumer Health News Tags: Health Source Type: news

Accuracy of Tumor Size Measurements Performed by Magnetic Resonance, Ultrasound and Mammography, and Their Correlation With Pathological Size in Primary Breast Cancer
ConclusionsMRI is the best predictor of tumor size in breast cancer. Histologic type and tumor size are key parameters when estimating tumor size and should be taken into account when planning surgery. Patient age does not interfere with the interpretation of imaging tests.ResumenIntroducciónEl objetivo de este estudio fue evaluar qué prueba de imagen de las empleadas para medir el tamaño del cáncer de mama primario preoperatorio (mamografía, ecografía o resonancia magnética (RM)) se correlacionó mejor con el tamaño del tumor en la pieza quirúrgica postoperatoria.MétodosAnálisis retrospectivo de mujeres con dia...
Source: Cirugia Espanola - August 20, 2019 Category: Surgery Source Type: research

Nivolumab and Eribulin in HER2 Negative Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer Intervention:   Drug: Nivolumab Sponsors:   Seoul National University Hospital;   Seoul National University Bundang Hospital;   Korean Cancer Study Group (KCSG);   Eisai Korea;   Ono pharmaceutical Korea Recruiting
Source: ClinicalTrials.gov - August 20, 2019 Category: Research Source Type: clinical trials

Effects of Alternative Healthy Eating Index-Based Diet on Inflammatory Markers and Breast Density in Healthy Participants
Conditions:   Healthy Subject;   Nulliparous Interventions:   Dietary Supplement: Dietary Intervention;   Procedure: Dual X-ray Absorptiometry Sponsors:   Fred Hutchinson Cancer Research Center;   Breast Cancer Research Foundation;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - August 20, 2019 Category: Research Source Type: clinical trials

Indentification of breast cancer subtypes sensitive to HCQ-induced autophagy inhibition
ConclusionTo conclude, basal-like breast cancer represented by SUM-190 cells may be most sensitive to HCQ induced autophagy inhibition and the mechanism might be relative to Ras/Raf/ERK signaling pathway.
Source: Pathology Research and Practice - August 20, 2019 Category: Pathology Source Type: research

U.S. Task Force Updates Breast Cancer Gene Testing Recommendations
TUESDAY, Aug. 20, 2019 -- Mutations in two genes -- BRCA1 and BRCA2 -- are known to significantly increase the risk of breast cancer, but experts have long debated which women should be tested for them. New recommendations from the U.S. Preventive...
Source: Drugs.com - Daily MedNews - August 20, 2019 Category: General Medicine Source Type: news

Sliding-cupping along meridian for lymphedema after breast cancer surgery: A randomized controlled trial
ConclusionCompared with CDT, the sliding-cupping along meridian combined with short-stretch elastic bandage wrapping for the treatment of lymphedema after breast cancer surgery was more effective.
Source: World Journal of Acupuncture Moxibustion - August 20, 2019 Category: Complementary Medicine Source Type: research

Which type of flap is more resistant to radiotherapy in breast cancer ?
Authors: Benderli Cihan Y PMID: 31424696 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

Secondary gastric cancer after breast cancer diagnosis might occur in younger lobular breast cancer.
Authors: Altundag K PMID: 31424695 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

The efficacy and reliability of sequential adjuvant anthracycline-based chemotherapy and weekly paclitaxel regimen in human epidermal growth factor receptor 2 negative breast cancer: A retrospective analysis of a multicentre study.
CONCLUSIONS: This multicentric retrospective study confirmed that sequential adjuvant therapy with anthracycline-based chemotherapy and paclitaxel for HER2 negative breast cancer is an effective and reliable regimen. PMID: 31424664 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

MicroRNA-155regulates the proliferation and metastasis of human breast cancers by targeting MAPK7.
CONCLUSION: Taken together, miR-155 may prove essential in the management of breast cancer. PMID: 31424663 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

The influence of reproductive factors on breast cancer risk in women with pathogenic mutations.
CONCLUSIONS: Breastfeeding represents a protective mechanism only in patients without genetic breast cancer predisposing mutations. Environmental and reproductive factors can impact the risk and the age of onset of breast cancer in patients carrying pathogenic mutations, but the mechanisms of action are not fully understood. PMID: 31424662 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

The functional role of the EZH2 gene in controlling breast cancer stem cells.
CONCLUSIONS: We conclude that the normal expression of EZH2 in cancer tissue controls cancer stem cell expansion, because it is highly elevated in EZH2-silencing cancer tissue. PMID: 31424661 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

MicroRNA-204 inhibits the proliferation and metastasis of breast cancer cells by targeting PI3K/AKT pathway.
CONCLUSION: We conclude that miR-204 regulates the proliferation and metastasis of the breast cancer cells and as such may prove to be an important therapeutic target. PMID: 31424660 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

Evaluation of the value of GATA3 combined with E-cadherin in the diagnosis of breast cancer.
CONCLUSION: Combined detection of GATA3 and E-cadherin is of great significance in the diagnosis and treatment of breast cancer, and it is expected to become an effective indicator for the diagnosis of breast cancer in the future. PMID: 31424658 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

Interaction of HCCR-1 and Bax in breast cancer.
CONCLUSIONS: HCCR-1 siRNA transfection causes significant increase in the apoptosis and decreases in the proliferation of MCF-7 cells.These effects are related to the upregulation of the Bax expression in the MCF-7 cells. PMID: 31424657 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research

Nordic Walking May Benefit Breast Cancer Patients Nordic Walking May Benefit Breast Cancer Patients
Nordic walking, an aerobic activity performed with walking poles similar to ski poles, may benefit patients with breast cancer, according to a review of existing research.Reuters Health Information
Source: Medscape General Surgery Headlines - August 20, 2019 Category: Surgery Tags: Hematology-Oncology News Source Type: news

Impact of breast magnetic resonance imaging on the locoregional staging and management of breast cancer
Conclusion: Breast MRI is an useful tool for the locoregional staging of breast cancer, because it provides useful information that can have a positive impact on patient treatment.Resumo Objetivo: Avaliar o impacto do uso da resson ância magnética (RM) no estadiamento pré-operatório do câncer de mama. Materiais e Métodos: Foram avaliadas 61 pacientes com carcinoma mamário submetidas a RM das mamas, no período de agosto de 2015 a abril de 2016. Um mastologista foi questionado sobre a conduta terapêutica indicada diant e dos dados da paciente e dos exames convencionais e, após realização da RM, foi novamente ques...
Source: Radiologia Brasileira - August 20, 2019 Category: Radiology Source Type: research

Parkin gene mutations are not common, but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients
Progression of breast cancer involves both genetic and epigenetic factors. Parkin gene has been identified as a tumor suppressor gene in the pathogenesis of various cancers. Nevertheless, the putative role of Par...
Source: BMC Cancer - August 20, 2019 Category: Cancer & Oncology Authors: Khushnuma Wahabi, Ahmad Perwez, Shabeena Kamarudheen, Zafar Iqbal Bhat, Anurag Mehta and M. Moshahid A. Rizvi Tags: Research article Source Type: research

Primary and Secondary Breast Lymphoma: Focus on Epidemiology and Imaging Features.
Abstract Aim of this study was to select all the cases of Primary (PBL) and Secondary (SBL) Breast Lymphoma from our breast unit since 01/01/2000, to obtain up-to-date data on the prevalence of this rare pathology and to analyze imaging features, with a special focus on CT. All pathological reports of breast biopsies performed from 01/01/2000 to 01/01/2019 were at first screened. Among them, we performed two different researches, looking for key words suggesting either a diagnosis of lymphoma or any other malignant disease. Using the Wiseman criteria, we identify PBL and SBL. All imaging features of PBL and SBL we...
Source: Pathology Oncology Research - August 20, 2019 Category: Pathology Authors: Picasso R, Tagliafico A, Calabrese M, Martinoli C, Pistoia F, Rossi A, Zaottini F, Derchi L Tags: Pathol Oncol Res Source Type: research

Epidermal Growth Factor Potentiates Migration of MDA-MB 231 Breast Cancer Cells by Increasing NaV1.5 Channel Expression.
In this study, by using an experimental strategy that combines cell and molecular biology assays with electrophysiological recording, we sought to determine whether the voltage-dependent sodium channel NaV1.5 regulates the migratory capacity of the human breast cancer cell line MDA-MB 231, when cells are maintained in the presence of epidermal growth factor (EGF), as an inductor of the epithelial-mesenchymal transition. RESULTS: Our data show that EGF stimulates the migratory capacity of MDA-MB 231 cells, by regulating the functional expression of NaV1.5 channels. Consistent with this, the stimulatory actions of the g...
Source: Oncology - August 20, 2019 Category: Cancer & Oncology Authors: González-González L, González-Ramírez R, Flores A, Avelino-Cruz JE, Felix R, Monjaraz E Tags: Oncology Source Type: research

A prognostic 10-lncRNA expression signature for predicting the risk of tumour recurrence in breast cancer patients.
In conclusion, our results demonstrated that this 10-lncRNA signature effectively grouped patients at low and high risk of disease recurrence. PMID: 31429520 [PubMed - as supplied by publisher]
Source: J Cell Mol Med - August 20, 2019 Category: Molecular Biology Authors: Tang J, Ren J, Cui Q, Zhang D, Kong D, Liao X, Lu M, Gong Y, Wu G Tags: J Cell Mol Med Source Type: research

Transcriptomic Analysis of Breast Cancer Stem Cells and Development of a pALDH1A1:mNeptune Reporter System for Live Tracking
This article is protected by copyright. All rights reserved
Source: Proteomics - August 20, 2019 Category: Biochemistry Authors: Nad ège Bidan, Justine Bailleul‐Dubois, Jérémy Duval, Marie Winter, Marie Denoulet, Karine Hannebicque, Ihsan Y. El‐Sayed, Christophe Ginestier, Violaine Forissier, Yukiko Matsunaga, Samuel Meignan, François Anquez, Sylvain Julien, Am Tags: Research Article Source Type: research

Quantitative Ultrasound Image Analysis of Axillary Lymph Nodes to Diagnose Metastatic Involvement in Breast Cancer
This study aimed to assess the potential of state-of-the-art ultrasound analysis techniques to non-invasively diagnose axillary lymph nodes involvement in breast cancer. After exclusion criteria, 105 patients were selected from two different hospitals. The 118 lymph node ultrasound images taken from these patients were divided into 53 cases and 65 controls, which made up the study series. The clinical outcome of each node was verified by ultrasound-guided fine needle aspiration, core needle biopsy or surgical biopsy.
Source: Ultrasound in Medicine and Biology - August 20, 2019 Category: Radiology Authors: David Coronado-Guti érrez, Gorane Santamaría, Sergi Ganau, Xavier Bargalló, Stefania Orlando, M. Eulalia Oliva-Brañas, Alvaro Perez-Moreno, Xavier P. Burgos-Artizzu Tags: Original Contribution Source Type: research

Suppression of the proliferation and invasion of breast cancer cells by ST7L occurs through inhibition of activation of Wnt/GSK-3 β/β-catenin signaling.
This article is protected by copyright. All rights reserved. PMID: 31429477 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Pharmacology and Physiology - August 20, 2019 Category: Drugs & Pharmacology Authors: Wang H, Sun L, Jiang J, Yu S, Zhou Q Tags: Clin Exp Pharmacol Physiol Source Type: research

Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell-induced bone pain.
This article is protected by copyright. All rights reserved. PMID: 31429474 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Pharmacology and Physiology - August 20, 2019 Category: Drugs & Pharmacology Authors: Shenoy PA, Kuo A, Leparc G, Hildebrandt T, Rust W, Nicholson JR, Corradini L, Vetter I, Smith MT Tags: Clin Exp Pharmacol Physiol Source Type: research

The Flick of a Switch: Conferring Survival Advantage to Breast Cancer Stem Cells Through Metabolic Plasticity
Within heterogeneous tumors, cancer stem cell (CSC) populations exhibit the greatest tumor initiation potential, promote metastasis, and contribute to therapy resistance. For breast cancer specifically, CSCs are identified by CD44highCD24low cell surface marker expression and increased aldehyde dehydrogenase activity. In general, bulk breast tumor cells possess altered energetics characterized by aerobic glycolysis. In contrast, breast CSCs appear to have adaptive metabolic plasticity that allows these tumor-initiating cells to switch between glycolysis and oxidative phosphorylation, depending on factors present in the tum...
Source: Frontiers in Oncology - August 20, 2019 Category: Cancer & Oncology Source Type: research

Short dental implant as alternative to long implant with bone augmentation of the atrophic posterior ridge: a systematic review and meta-analysis of RCTs
Conclusions: Short dental implants seem to be an effective alternative treatment for the atrophic posterior ridge. The pooled data revealed that short dental implants have statistically less marginal bone loss and fewer postoperative complications when compared to standard-length dental implants with augmentation. However, there are no statistically significant differences in regard to implant failure.
Source: Quintessence International - August 19, 2019 Category: Dentistry Source Type: research

Prolactin hormone exerts anti-tumorigenic effects in HER-2 overexpressing breast cancer cells through regulation of stemness
ConclusionTogether these results emphasize an anti-tumorigenic role with a potential therapeutic value for PRL in HER-2 and luminal B breast cancer subtypes targeting the cancer stem-like cells.
Source: Stem Cell Research - August 19, 2019 Category: Stem Cells Source Type: research

A Study of Ipatasertib Plus Palbociclib and Fulvestrant Versus Placebo Plus Palbociclib and Fulvestrant in Hormone Receptor Positive and HER2 Negative Locally Advanced Unresectable or Metastatic Breast Cancer
Condition:   Breast Cancer Interventions:   Drug: Ipatasertib;   Drug: Placebo;   Drug: Palbociclib;   Drug: Fulvestrant Sponsor:   Hoffmann-La Roche Not yet recruiting
Source: ClinicalTrials.gov - August 19, 2019 Category: Research Source Type: clinical trials

Real-world Study for the Safety of Albumin-Bound Paclitaxel in Recurrent or Metastatic Breast Cancer
Condition:   Breast Cancer Intervention:   Other: Observational study Sponsor:   CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Not yet recruiting
Source: ClinicalTrials.gov - August 19, 2019 Category: Research Source Type: clinical trials

FSRT in Breast Cancer Patients With Brain Metastases
Conditions:   Breast Cancer;   Brain Metastases Intervention:   Radiation: Fractionated stereotactic radiotherapy(FSRT) Sponsor:   Fudan University Recruiting
Source: ClinicalTrials.gov - August 19, 2019 Category: Research Source Type: clinical trials

A Study of Ipatasertib Plus Palbociclib and Fulvestrant Versus Placebo Plus Palbociclib and Fulvestrant in Hormone Receptor Positive and HER2 Negative Locally Advanced Unresectable or Metastatic Breast Cancer
Condition:   Breast Cancer Interventions:   Drug: Ipatasertib;   Drug: Placebo;   Drug: Palbociclib;   Drug: Fulvestrant Sponsor:   Hoffmann-La Roche Not yet recruiting
Source: ClinicalTrials.gov - August 19, 2019 Category: Research Source Type: clinical trials

Real-world Study for the Safety of Albumin-Bound Paclitaxel in Recurrent or Metastatic Breast Cancer
Condition:   Breast Cancer Intervention:   Other: Observational study Sponsor:   CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Not yet recruiting
Source: ClinicalTrials.gov - August 19, 2019 Category: Research Source Type: clinical trials

FSRT in Breast Cancer Patients With Brain Metastases
Conditions:   Breast Cancer;   Brain Metastases Intervention:   Radiation: Fractionated stereotactic radiotherapy(FSRT) Sponsor:   Fudan University Recruiting
Source: ClinicalTrials.gov - August 19, 2019 Category: Research Source Type: clinical trials