Log in to search using one of your social media accounts:

British Journal of Ophthalmology British Journal of Ophthalmology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

This page shows you the latest items in this publication.

The relationship between anti-vascular endothelial growth factor and fibrosis in proliferative retinopathy: clinical and laboratory evidence
Conclusions Anti-vascular endothelial growth factor treatment likely accelerates fibrosis in PDR patients via upregulation of TGFβ2, CTGF and CNTF, suggesting the importance of adjunctive therapy for retinal fibrosis. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Zhang, Q., Qi, Y., Chen, L., Shi, X., Bai, Y., Huang, L., Yu, W., Jiang, Y., Zhao, M., Li, X. Tags: Retina, Editor's choice Original articles - Laboratory science Source Type: research

Repeatability of selective laser trabeculoplasty
Conclusions Repeat SLT can restore IOP control in eyes with open-angle glaucoma that have previously undergone successful initial SLT. Repeat SLT achieves comparable absolute level of IOP control achieved by initial SLT. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Polat, J., Grantham, L., Mitchell, K., Realini, T. Tags: Ophthalmologic surgical procedures, Angle, Intraocular pressure, Glaucoma Original articles - Clinical science Source Type: research

Long-term surgical outcomes and factors for recurrence after unilateral lateral rectus muscle recession
Conclusions The overall long-term successful alignment rate of ULR for 15–24 PD of IXT was good. However, patients with 20–24 PD of IXT showed worse prognosis compared with 15–19 PD of IXT. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Lyu, I. J., Park, K.-A., Oh, S. Y. Tags: Paediatrics, Muscles, Neurology Original articles - Clinical science Source Type: research

Saccadic vector optokinetic perimetry in children with neurodisability or isolated visual pathway lesions: observational cohort study
Conclusions While SVOP is highly accessible to children, many cannot complete a full 40-point test. Agreement with current standard tests is moderate to poor. Abnormal saccades cause an apparent non-specific visual field defect. In children with glaucoma or nystagmus SVOP calibration often fails. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Tailor, V., Glaze, S., Unwin, H., Bowman, R., Thompson, G., Dahlmann-Noor, A. Tags: Angle, Intraocular pressure, Glaucoma, Epidemiology Original articles - Clinical science Source Type: research

The SPARCS: a novel assessment of contrast sensitivity and its reliability in patients with corrected refractive error
Conclusions SPARCS appears to be a reliable assessment for CS. The difference in CS among myopes, emmetropes and hyperopes wearing their habitual correction was statistically insignificant in this study. Clinical trial number NCT01300949, post results (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Sun, Y., Erdem, E., Lyu, A., Zangalli, C., Wizov, S. S., Lo, D., Spaeth, E. E., Richman, J., Spaeth, G. L. Tags: Optic nerve, Optics and refraction, Epidemiology Original articles - Clinical science Source Type: research

Autologous simple limbal epithelial transplantation for unilateral limbal stem cell deficiency: multicentre results
Conclusion Autologous SLET is an effective and safe modality for treatment of unilateral LSCD. Clinical success rates and visual acuity improvement are equal to or better than those reported with earlier techniques. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Vazirani, J., Ali, M. H., Sharma, N., Gupta, N., Mittal, V., Atallah, M., Amescua, G., Chowdhury, T., Abdala-Figuerola, A., Ramirez-Miranda, A., Navas, A., Graue-Hernandez, E. O., Chodosh, J. Tags: Ophthalmologic surgical procedures Original articles - Clinical science Source Type: research

Incidence, severity and outcomes of traumatic wound dehiscence following penetrating and deep anterior lamellar keratoplasty
Conclusions Traumatic wound dehiscence may occur following minor trauma, even years after PK and frequently causes severe vision loss. Patients should be advised of this longer term risk and protective eye-wear should be encouraged by eye care providers. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Meyer, J. J., McGhee, C. N. J. Tags: Ophthalmologic surgical procedures Original articles - Clinical science Source Type: research

Bilateral IgG4-related ophthalmic disease: a strong indication for systemic imaging
Conclusions Bilateral IgG4-ROD is strongly associated with extra-ophthalmic IgG4-RD. We recommend that imaging of the neck, chest, abdomen and pelvis be performed for all bilateral cases. Systemic imaging should also be considered in unilateral cases as a significant proportion of these patients will also have extra-ophthalmic disease. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Wu, A., Andrew, N. H., McNab, A. A., Selva, D. Tags: Original articles - Clinical science Source Type: research

Combined positron emission tomography/computed tomography (PET/CT) for imaging of orbital tumours and tumours extending into the orbit
Conclusion PET/CT is a sensitive tool for the detection and localisation of orbital masses, enabling assessment of both morphology and cell metabolism. Detailed imaging of the head and neck region with a small field-of-view should be performed when suspecting lymphatic metastases. As metastatic disease to the orbit is associated with advanced disease, focus should be laid on whole-body imaging for staging of these patients. Different radiopharmaceutical tracers can be applied to distinguish the origin of orbital metastases. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Klingenstein, A., Mueller-Lisse, G.-U., Haug, A. R., Garip-Kuebler, A., Miller, C. V., Hintschich, C. R. Tags: Eye (globe) Original articles - Clinical science Source Type: research

Iris autofluorescence in Fuchs heterochromic uveitis
Conclusions Characteristic autofluorescence patterns appeared in eyes diagnosed with FHU. Near-infrared autofluorescence is a promising objective technique to document the iris changes in FHU. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Liu, Q., Jia, Y., Zhang, S., Xie, J., Chang, X., Hou, J., Li, G., Koch, D. D., Wang, L. Tags: Original articles - Clinical science Source Type: research

Lymphopenia as a predictor of sarcoidosis in patients with uveitis
Conclusions Significant lymphopenia (<1.0x109/L) is an independent predictor of sarcoidosis in new patients presenting with uveitis. We recommend that diagnostic criteria for SAU should be modified to include this phenomenon. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Jones, N. P., Tsierkezou, L., Patton, N. Tags: Epidemiology Original articles - Clinical science Source Type: research

Occurrence and risk factors for retinal detachment after pars plana vitrectomy in acute postcataract bacterial endophthalmitis
Conclusions RD is a major and severe complication of PPV performed in patients with acute postcataract endophthalmitis. Retinal vasculitis is a major risk factor of RD after PPV. Anatomical and functional outcome remain poor. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Chiquet, C., Aptel, F., Combey-de Lambert, A., Bron, A. M., Campolmi, N., Palombi, K., Thuret, G., Rouberol, F., Cornut, P.-L., Creuzot-Garcher, C., On behalf of the FRIENDS (French Institutional Endophthalmitis Study) group, Vandenesch, Maurin, Lafontain Tags: Ophthalmologic surgical procedures, Choroid, Eye (globe), Lens and zonules, Retina, Vitreous, Epidemiology Original articles - Clinical science Source Type: research

Iatrogenic retinal breaks in ultrahigh-speed 25-gauge vitrectomy: a prospective study of elective cases
Conclusions UHS 25-gauge transconjunctival sutureless vitrectomy is a safe procedure for treatment of elective vitreous-retina cases. The risk of developing iatrogenic breaks seems to be correlated with adhesion of the posterior vitreous hyaloid. Other complications, such as rhegmatogenous retinal detachment or hypotony, were similar to previous reports. No correlation was found between iatrogenic retina breaks and other complications. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Mura, M., Barca, F., Dell'Omo, R., Nasini, F., Peiretti, E. Tags: Ophthalmologic surgical procedures, Retina, Vitreous Original articles - Clinical science Source Type: research

Wide field of view swept-source optical coherence tomography for peripheral retinal disease
Conclusions WFOV OCT can be used to examine both peripheral retinal pathology and the posterior pole within a single volume acquisition. SLO had the greatest FOV, but does not provide depth information. Future studies using widefield OCT systems will help further delineate the role of WFOV OCT to quantitatively assess and monitor peripheral retinal disease in three dimensions. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: McNabb, R. P., Grewal, D. S., Mehta, R., Schuman, S. G., Izatt, J. A., Mahmoud, T. H., Jaffe, G. J., Mruthyunjaya, P., Kuo, A. N. Tags: Eye (globe), Retina Original articles - Clinical science Source Type: research

Choroidal thickness maps from spectral domain and swept source optical coherence tomography: algorithmic versus ground truth annotation
Conclusion Choroidal thickness measurements of SD-OCT and SS-OCT indicate that these two devices are interchangeable with a trend of choroidal thickness measurements being slightly thicker on SD-OCT with limited clinical relevance. Use of an automated algorithm to segment choroidal thickness was validated in healthy volunteers. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Philip, A.-M., Gerendas, B. S., Zhang, L., Faatz, H., Podkowinski, D., Bogunovic, H., Abramoff, M. D., Hagmann, M., Leitner, R., Simader, C., Sonka, M., Waldstein, S. M., Schmidt-Erfurth, U. Tags: Original articles - Clinical science Source Type: research

Changes observed in diabetic retinopathy: eight-year follow-up of a Spanish population
Conclusions An increase in the incidence of DR and DMO was observed, especially in the younger patients aged between 31 and 70 years. This is linked to bad metabolic control of DM. Our results suggest a greater number of ocular complications in the near future, such as neovascular glaucoma, if these current findings are not addressed. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Romero-Aroca, P., de la Riva-Fernandez, S., Valls-Mateu, A., Sagarra-Alamo, R., Moreno-Ribas, A., Soler, N. Tags: Public health, Angle, Intraocular pressure, Retina, Open access, Glaucoma, Epidemiology Original articles - Clinical science Source Type: research

Relationship of retinal vascular calibre and diabetic retinopathy in Chinese patients with type 2 diabetes mellitus: the Desheng Diabetic Eye Study
Conclusions In the current study, wider venular calibre, but not arteriolar calibre, was shown to be associated with development and increased severity of DR independently from other risk factors in a Chinese diabetic population. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Yang, X., Deng, Y., Gu, H., Ren, X., Lim, A., Snellingen, T., Liu, X., Wang, N., Won Pak, J., Liu, N., Danis, R. P., Reimers, Gangaputra, Narkar, Kubiak Tags: Retina, Epidemiology Original articles - Clinical science Source Type: research

Past physical activity and age-related macular degeneration: the Melbourne Collaborative Cohort Study
Conclusions Past frequent vigorous exercise may be inversely related to the presence of intermediate AMD in women. Further studies are needed to confirm whether physical activity and exercise have a protective effect for AMD. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: McGuinness, M. B., Karahalios, A., Simpson, J. A., Guymer, R. H., Robman, L. D., Hodge, A. M., Cerin, E., Giles, G. G., Finger, R. P. Tags: Public health, Retina, Epidemiology Original articles - Clinical science Source Type: research

Visual acuity loss in patients with age-related macular degeneration measured using a novel high-pass letter chart
Conclusions VA measurements with the MAC chart appear to be more sensitive to functional loss in AMD compared with conventional letter charts, with similar TRV. Simulations indicate this may be because the high-pass filtered letters are more vulnerable to undersampling as a result of retinal cell loss in the disease process. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Shah, N., Dakin, S. C., Dobinson, S., Tufail, A., Egan, C. A., Anderson, R. S. Tags: Retina Original articles - Clinical science Source Type: research

Changing from a pro re nata treatment regimen to a treat and extend regimen with ranibizumab in neovascular age-related macular degeneration
Conclusions A TE regimen can improve and stabilise patient outcomes in nAMD compared with PRN, with the potential to reduce the healthcare resource burden incurred from fixed monitoring requirements. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Hatz, K., Prünte, C. Tags: Retina Original articles - Clinical science Source Type: research

Comparison of photodynamic therapy, ranibizumab/bevacizumab or combination in the treatment of myopic choroidal neovascularisation: a 9-year-study from a single centre
Conclusion Combination of vPDT and intravitreal anti-VEGF (ranibizumab/bevacizumab) was associated with better visual outcomes and higher rates of regression in eyes with myopic CNV as compared with monotherapy with PDT or anti-VEGF. Larger size of CNV, and high refractive error were independent risk factors for poor visual outcomes. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Rishi, P., Rishi, E., Bhende, M., Agarwal, V., Vyas, C. H., Valiveti, M., Bhende, P., Rao, C., Susvar, P., Sen, P., Raman, R., Khetan, V., Murali, V., Ratra, D., Sharma, T. Tags: Choroid, Optic nerve, Optics and refraction Original articles - Clinical science Source Type: research

Retina specialists treating cystoid macular oedema secondary to retinal vein occlusion recommend different treatments for patients than they would choose for themselves
Conclusions Physicians should be aware that cognitive biases exist and take this into consideration when making treatment recommendations for their patients. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Wang, M. D., Jeng-Miller, K. W., Feng, H. L., Prenner, J. L., Fine, H. F., Shah, S. P. Tags: Retina Original articles - Clinical science Source Type: research

Genetic manipulation for inherited neurodegenerative diseases: myth or reality?
Rare genetic diseases affect about 7% of the general population and over 7000 distinct clinical syndromes have been described with the majority being due to single gene defects. This review will provide a critical overview of genetic strategies that are being pioneered to halt or reverse disease progression in inherited neurodegenerative diseases. This field of research covers a vast area and only the most promising treatment paradigms will be discussed with a particular focus on inherited eye diseases, which have paved the way for innovative gene therapy paradigms, and mitochondrial diseases, which are currently generatin...
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Yu-Wai-Man, P. Tags: Open access, Neurology Review Source Type: research

Spring-action Apparatus for Fixation of Eyeball (SAFE): a novel, cost-effective yet simple device for ophthalmic wet-lab training
Achieving a formed and firm eyeball which is stably fixed in a holding device is a major challenge of surgical wet-lab training. Our innovation, the ‘Spring-action Apparatus for Fixation of Eyeball (SAFE)’ is a robust, simple and economical device to solve this problem. It consists of a hollow iron cylinder to which a spring-action syringe is attached. The spring-action syringe generates vacuum and enables reliable fixation of a human or animal cadaveric eye on the iron cylinder. The rise in intraocular pressure due to vacuum fixation can be varied as per need or nature of surgery being practised. A mask-fixed ...
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Ramakrishnan, S., Baskaran, P., Fazal, R., Sulaiman, S. M., Krishnan, T., Venkatesh, R. Tags: Ophthalmologic surgical procedures, Lens and zonules Innovations Source Type: research

Uveitis is predominantly of infectious origin in a high HIV and TB prevalence setting in rural South Africa
Conclusions Microbial aetiology of uveitis is common in areas where HIV and TB are endemic. In these settings, a high index of suspicion for infectious origin of uveitis is warranted. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Schaftenaar, E., Meenken, C., Baarsma, G. S., Khosa, N. S., Luijendijk, A., McIntyre, J. A., Osterhaus, A. D. M. E., Verjans, G. M. G. M., Peters, R. P. H. Tags: Epidemiology Global issues Source Type: research

One hundred years of retinal detachment surgery
One hundred years ago this year a major conflict was being fought in France on the banks of the river Somme, which some historians argue was the turning point of the World War I.1 As that battle was raging some thousands of miles to the south, in the small town of Lausanne in Switzerland another turning point was occurring not in a geopolitical context but one which would bring credit to mankind; the Gonin method to repair retinal detachments (figure 1). Retinal detachments had been recognised prior to the invention of the ophthalmoscope in 1851, but more often had been included in that undifferentiated clinical grouping k...
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Polkinghorne, P. J. Tags: Retina, Vision, Neurology Editorials Source Type: research

Highlights from this issue
Shah et al (see page 1332) For cystoid macular edema secondary to a retinal vein occlusion, specialists would be more likely to choose bevacizumab, and would be less likely to choose aflibercept than if they were choosing the drug to treat their own disease. Rishi et al (see page 1337) Combination Photodynamic therapy and intravitreal anti-VEGF (Ranibizumab/Bevacizumab) is associated with better outcomes in eyes with myopic CNV as compared to monotherapy with PDT or anti-VEGF. Prünte et al (see page 1341) Switching from a pro re nata (PRN) to treat and extend regimen of ranibizumab in patients with nAMD resulted in...
Source: British Journal of Ophthalmology - September 22, 2016 Category: Opthalmology Authors: Barton, K., Chodosh, J., Jonas, J. Tags: At a glance Source Type: research

S100A8 and S100A9 proteins are expressed by human corneal stromal dendritic cells
Conclusions A8 and A9 expression may distinguish between subpopulations of DC that reside in different regions of the human cornea and may influence their maturation status. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Wilkinson, A., Kawaguchi, N., Geczy, C., Di Girolamo, N. Tags: Original articles - Laboratory science Source Type: research

Clinical manifestations and outcome of tuberculous sclerokeratitis
Conclusions Antituberculous medications can lead to complete resolution of the sclerokeratitis without concomitant use of steroids, or other anti-inflammatory agents. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Shoughy, S. S., Jaroudi, M. O., Tabbara, K. F. Tags: Cornea, Ocular surface, Sclera and apisclera Original articles - Clinical science Source Type: research

Implications of enlarged infraorbital nerve in idiopathic orbital inflammatory disease
Conclusions Patients with ION-enlarged IOI showed distinct clinical and radiological characteristics. As IOI accompanied by ION enlargement showed significantly higher steroid dependency and recurrence rate, a more careful follow-up of patients during steroid tapering might be helpful to prevent recurrence of IOI. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Lee, K. H., Han, S. H., Yoon, J. S. Tags: Orbit, Neurology Original articles - Clinical science Source Type: research

Scleritis associated with relapsing polychondritis
Conclusions Scleritis may be the first manifestation whose study leads to the diagnosis of RP. Scleritis associated with RP is more often bilateral, necrotising, recurrent and associated with decrease of vision than scleritis associated with other SIMD. About 69.2% of patients will have an additional SIMD disorder. Scleritis associated with RP most often will require immunomodulatory therapy. Occasionally, scleritis with RP may appear while using antitumor necrosis factor α agents. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Sainz-de-la-Maza, M., Molina, N., Gonzalez-Gonzalez, L. A., Doctor, P. P., Tauber, J., Foster, C. S. Tags: Angle, Choroid, Cornea, Intraocular pressure, Ocular surface, Sclera and apisclera, Vision, Neurology Original articles - Clinical science Source Type: research

Clinical features, microbiological profiles and treatment outcome of lacrimal plug-related canaliculitis compared with those of primary canaliculitis
Conclusions In comparison with primary canaliculitis, plug-related canaliculitis appear to be more prevalent in women and show a different microbiological profile. Retrieval of infected plug by canaliculotomy and adequate antibiotics can achieve a good outcome. Long-term follow-up is required because canaliculitis may develop several years after plug insertion. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Huang, Y.-Y., Yu, W.-K., Tsai, C.-C., Kao, S.-C., Kau, H.-C., Liu, C. J.-L. Tags: Original articles - Clinical science Source Type: research

Enlargement of the superior rectus and superior oblique muscles causes intorsion in Graves eye disease
Conclusions Preoperative SR and/or SO muscle enlargement appear to be a primary contributing factor relating to preoperative and postoperative intorsion in patients with GED-associated strabismus. Patients with only small amounts of preoperative extorsion (<3.5°) in the presence of tight IRs should be carefully evaluated for possible SR and/or SO involvement by CT or MRI scan to predict those at risk for and plan for prevention/treatment of postoperative intorsion. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Wei, Y., Kang, X. l., Del Monte, M. A. Tags: Muscles, Neurology Original articles - Clinical science Source Type: research

Association between light-to-dark changes in angle width and iris parameters in light, dark and changes from light-to-dark conditions
Conclusions Evaluation of iris parameters in light, dark and changes from light-to-dark conditions demonstrated that IT750, IT2000, IArea and PD in light conditions are significant predictors of light-to-dark changes in angle width. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Lee, R. Y., Lin, S.-C., Chen, R. I., Barbosa, D. T., Lin, S. C. Tags: Epidemiology Original articles - Clinical science Source Type: research

Comparison of trabeculectomy versus Ex-PRESS: 3-year follow-up
Conclusions We found no difference in success rates, mean IOP or other secondary outcomes between Ex-PRESS and trabeculectomy after 3 years of follow-up. Trial registration number NCT01263561; post results. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Gonzalez-Rodriguez, J. M., Trope, G. E., Drori-Wagschal, L., Jinapriya, D., Buys, Y. M. Tags: Ophthalmologic surgical procedures, Angle, Intraocular pressure, Glaucoma Original articles - Clinical science Source Type: research

Monitoring ocular hypertension, how much and how often? A cost-effectiveness perspective
Conclusions For confirmed OHT, glaucoma monitoring more frequently than every 2 years is unlikely to be efficient. Primary treatment and minimal monitoring (assessing treatment responsiveness (IOP)) could be considered; however, further data to refine glaucoma risk prediction models and value patient preferences for treatment are needed. Consideration to innovative and affordable service redesign focused on treatment responsiveness rather than more glaucoma testing is recommended. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Hernandez, R., Burr, J., Vale, L., Azuara-Blanco, A., Cook, J., Banister, K., Tuulonen, A., Ryan, M., for the Surveillance of Ocular Hypertension Study group, Botello-Pinzon, Takwoingi, Vazquez-Montes, Elders, Asaoka, van der Schoot, Fraser, King, Lemij, Tags: Angle, Intraocular pressure, Glaucoma Original articles - Clinical science Source Type: research

Microcatheter-assisted trabeculotomy versus rigid probe trabeculotomy in childhood glaucoma
Conclusion Microcatheter-assisted circumferential trabeculotomy is a more effective treatment and is as safe as traditional trabeculotomy with a rigid probe for primary congenital glaucoma in the early postoperative course. Trial registration number ChiCTR-OCC-15005789, Results. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Shi, Y., Wang, H., Yin, J., Li, M., Zhang, X., Xin, C., Chen, X., Wang, N. Tags: Angle, Intraocular pressure, Glaucoma Original articles - Clinical science Source Type: research

The height of the posterior staphyloma and corneal hysteresis is associated with the scleral thickness at the staphyloma region in highly myopic normal-tension glaucoma eyes
Conclusion Subfoveal scleral thinning and non-uniform posterior staphyloma were closely related in highly myopic NTG eyes. Corneal hysteresis, corneal resistance factor and the nasal posterior staphyloma height were associated with the scleral thickness. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Park, J. H., Choi, K.-R., Kim, C. Y., Kim, S. S. Tags: Angle, Intraocular pressure, Optic nerve, Glaucoma, Optics and refraction Original articles - Clinical science Source Type: research

Perceptual visual dysfunction, physical impairment and quality of life in Bangladeshi children with cerebral palsy
Conclusions PVD is an important contributor in reducing quality of life in children with CP, independent of motor disability and acuity impairment. Better characterisation of PVD is important to help design interventions for affected children, which may improve their quality of life. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Mitry, D., Williams, C., Northstone, K., Akter, A., Jewel, J., Khan, N., Muhit, M., Gilbert, C. E., Bowman, R. Tags: Paediatrics, Neurology Original articles - Clinical science Source Type: research

Correlation of central visual function and ROP risk factors in prematures with and without acute ROP at the age of 6-13 years: the Giessen long-term ROP study
Conclusions Low BW, GA and increasing severity of spontaneously resolving ROP were associated with significantly decreased central visual function. In addition to VA, LIS measurement further describes foveal function and is a unique parameter to assess parafoveal function. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Bowl, W., Lorenz, B., Stieger, K., Schweinfurth, S., Holve, K., Friedburg, C., Andrassi-Darida, M. Tags: Paediatrics, Retina, Editor's choice, Epidemiology Original articles - Clinical science Source Type: research

Macular nerve fibre and ganglion cell layer changes in acute Leber's hereditary optic neuropathy
Conclusions The natural history of GC-IPL thinning follows a specific pattern of reduction, reflecting the anatomical course of papillomacular fibres. Month 6 represents the end of GC-IPL loss. GC-IPL and mRNFL thinning is detectable before onset of visual loss. These observations can help future therapeutic approaches for both LHON carriers at high risk of conversion and patients with acute early LHON. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Balducci, N., Savini, G., Cascavilla, M. L., La Morgia, C., Triolo, G., Giglio, R., Carbonelli, M., Parisi, V., Sadun, A. A., Bandello, F., Carelli, V., Barboni, P. Tags: Optic nerve, Neurology Original articles - Clinical science Source Type: research

The extent of stretched lamellar cleavage and visual acuity in macular pseudoholes
Conclusions Although advanced cleavage in macular pseudohole is associated with worse VA before surgery, even an advanced pseudohole could show favourable visual recovery after surgery. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Toyama, T., Roggia, M. F., Yamaguchi, T., Noda, Y., Ueta, T. Tags: Ophthalmologic surgical procedures Original articles - Clinical science Source Type: research

Phase IIb clinical trial of ranibizumab for the treatment of uveitic and idiopathic choroidal neovascular membranes
Conclusion Patients gained vision (mean of 21 letters at 12 months) and showed reduced CST. These results support the continued use of ranibizumab in the treatment of iCNV. Trial registration number 2008-007476-19, results. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Carreno, E., Moutray, T., Fotis, K., Lee, R. W. J., Dick, A. D., Ross, A. H., Bailey, C. Tags: Original articles - Clinical science Source Type: research

Epidemiology and clinical characteristics of rhegmatogenous retinal detachment in Taiwan
Conclusions The annual incidence of RRD in Taiwan is comparable to most Western countries, with a relatively younger mean age. The male patients were more susceptible to retinal detachment in almost all age groups. Retinal detachment in patients with high myopia was associated with a younger age at onset. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Chen, S.-N., Lian, I.-B., Wei, Y.-J. Tags: Ophthalmologic surgical procedures, Lens and zonules, Optic nerve, Retina, Optics and refraction, Epidemiology Original articles - Clinical science Source Type: research

Vitrectomy After ocriplasmin for VitreOmacular adhesion Or Macular hole (VAVOOM) study
Conclusions Eyes with persistent symptomatic VMT and/or MH have similarly high rates of pathology resolution as well as similar VA gains regardless of whether they received ocriplasmin prior to PPV. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Greven, M. A., Garg, S., Chiu, B., Shah, S. P., Wolfe, J., Fine, H. F., Roth, D. B., Robinson, J., Mong, J., Hsu, J., Regillo, C., Ho, A., Haller, J. A. Tags: Ophthalmologic surgical procedures, Retina Original articles - Clinical science Source Type: research

Incidence and factors associated with complications of sutured and sutureless cataract surgery following pars plana vitrectomy at a tertiary referral centre in Turkey
Conclusions Longer duration of PPV surgery, a longer interval from PPV to silicone oil extraction, prior 20-gauge PPV, and 20-gauge PPV with scleral buckling surgery seem to influence the safety and outcomes of cataract surgery. Sutureless phacoemulsification in vitrectomised eyes was not associated with a higher incidence of endophthalmitis, suprachoroidal effusion or haemorrhage. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Hocaoglu, M., Karacorlu, M., Sayman Muslubas, I., Ozdemir, H., Arf, S., Uysal, O. Tags: Ophthalmologic surgical procedures, Choroid, Eye (globe), Lens and zonules Original articles - Clinical science Source Type: research

Evaluation and comparison of the new swept source OCT-based IOLMaster 700 with the IOLMaster 500
Conclusions Although the agreement between the two devices was excellent, the IOLMaster 700 was more effective in obtaining biometric measurements in eyes with posterior subcapsular and dense nuclear cataracts. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Akman, A., Asena, L., Güngör, S. G. Tags: Lens and zonules, Open access, Epidemiology Original articles - Clinical science Source Type: research

Corneal powers measured with a rotating Scheimpflug camera
Conclusions Pentacam rotating camera assessment of total corneal power over the central 3.0 mm zone differed significantly for simulated keratometry, equivalent power and Snell's law ray tracing. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Naeser, K., Savini, G., Bregnhoj, J. F. Tags: Original articles - Clinical science Source Type: research

Five-year results of Small Incision Lenticule Extraction (ReLEx SMILE)
Conclusions This first long-term study demonstrates SMILE to be an effective, stable and safe procedure for treatment of myopia and myopic astigmatism. Clinical trial number DE/CA93/KP/07/001. Post-results. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Blum, M., Täubig, K., Gruhn, C., Sekundo, W., Kunert, K. S. Tags: Lens and zonules, Optic nerve, Optics and refraction Original articles - Clinical science Source Type: research

Evaluation of point-of-care test for elevated tear matrix metalloproteinase 9 in post-LASIK dry eyes
Conclusions Only half of post-LASIK dry eyes were found to have significant inflammation associated with elevated MMP-9. The OSDI is useful to non-specifically identify patients with symptomatic dry eye while the InflammaDry determined which patients with dry eye were associated with significant inflammation that may guide therapeutic management decisions. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 17, 2016 Category: Opthalmology Authors: Chan, T. C. Y., Ye, C., Chan, K. P., Chu, K. O., Jhanji, V. Tags: Ophthalmologic surgical procedures Original articles - Clinical science Source Type: research