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Atomoxetine and escitalopram migrate the derangement of the temporomandibular joint morphologic and histologic changes in rats exposed to stress-induced depression
CONCLUSION: The present study findings indicated the change in TMJ characteristics, especially on the superficial part of the condylar head in the depression group. Concerning the applicability of the different antidepressants, depression with the treatment of atomoxetine has the most disadvantages due to bone porosity and cartilaginous condyle changes.PMID:37518767 | DOI:10.2334/josnusd.23-0077
Source: Journal of oral science - July 30, 2023 Category: Dentistry Authors: Thanatta Songphaeng Sarawut Lapmanee Sakkarin Bhubhanil Kamonchanok Momdee Catleya Rojviriya Kemporn Kitsahawong Pattama Chailertvanitkul Jariya U Welbat Supawich Morkmued Source Type: research

A Young Adult Patient with Rheumatoid Disorder Presents for the Evaluation of Limited Mouth Opening
Juvenile Idiopathic Arthritis (JIA), formerly known as Juvenile Rheumatoid Arthritis, includes all forms of chronic arthritis with unknown etiology that occurs before the age of sixteen. Clinical practice guidelines for JIA management have been evolving for the past 10  years. JIA affects approximately 1 per 1000 children in the U.S. causing short and long-term disability. Polyarticular JIA represents 30% to 40% of JIA and affects five or more joints within 6 months of onset, including the smaller joints, such as the temporomandibular joint (TMJ). TMJ involvemen t in JIA is between 17% and 87% and can cause craniofacial ...
Source: Dental Clinics of North America - July 27, 2023 Category: Dentistry Authors: Sara N. Aldosary, Takako I. Tanaka Source Type: research

Short-term recovery after implant versus resection arthroplasty in trapeziometacarpal joint osteoarthritis
J Hand Surg Eur Vol. 2023 Jul 21:17531934231188407. doi: 10.1177/17531934231188407. Online ahead of print.ABSTRACTWe compared the short-term recovery of patients treated with trapeziometacarpal joint (TMJ) implant arthroplasty versus resection-suspension-interposition (RSI) arthroplasty. Implant patients (n = 147) had a better 3-month postoperative brief Michigan Hand Outcomes Questionnaire (MHQ) score (mean 82) compared to RSI patients (n = 127), who had a mean score of 69. Key pinch strength at 3 months was also higher in the implant group compared to the RSI group (6.8 kg vs. 3.1 kg). At 1 year, both groups had similar ...
Source: Hand Surgery - July 21, 2023 Category: Surgery Authors: Daniel B Herren Miriam Marks Sara Neumeister Stephan Schindele Source Type: research

TMJ anterior disc displacement anchorage surgery: a retrospective study based on a suture-free titanium screw strategy
ConclusionAnteriorly displaced articular disc can be repositioned by a suture-free titanium screw strategy. This technique is an alternative method to address ADDwoR.
Source: Clinical Oral Investigations - July 19, 2023 Category: Dentistry Source Type: research

IL-38 suppresses macrophage M1 polarization to ameliorate synovial inflammation in the TMJ via GLUT-1 inhibition
CONCLUSIONS: IL-38 is a novel anti-inflammatory factor that contributes to alleviating TMJ inflammation by inhibiting macrophage M1 polarization, thereby ameliorating chondrocyte inflammation and restoring TMJ homeostasis.PMID:37463548 | DOI:10.1016/j.intimp.2023.110619
Source: International Immunopharmacology - July 18, 2023 Category: Allergy & Immunology Authors: Ping Luo Mingyuan Du Qiao Sun Tingting Zhao Hong He Source Type: research

Effects of glucose concentration and oxygen partial pressure on the respiratory metabolism of sheep temporomandibular joint disc cells
According to this study, the primary metabolic pathway of TMJ disc cells is glycolysis. It was concluded that hypoxic conditions and normal glucose concentrations are needed for the growth of TMJ disc cells. Glucose is necessary to ensure cell survival, extracellular matrix synthesis and mitochondrial function. Glucose deficiency may be related to disc degeneration, aging and disease mechanisms.PMID:37456155 | PMC:PMC10347106 | DOI:10.3892/etm.2023.12086
Source: Experimental and Therapeutic Medicine - July 17, 2023 Category: General Medicine Authors: Fangrui Dong Pengfei Zhang Bin Ma Guangjie Bao Hong Kang Source Type: research