TWiV 1037: Antibodies, the good (CoV), the bad (Ad), the beautiful
TWiV reviews evidence that symptomatic adenovirus infection leads to thrombocytopenia, thrombosis, and production of anti-platelet factor 4 antibodies similar to the rare disorder seen after immunization with adenoviral vectored COVID-19 vaccines, and a monoclonal antibody isolated from a SARS survivor, following vaccination with a SARS-CoV-2 spike mRNA vaccine, that neutralizes a broad collection of ACE2-binding sarbecoviruses. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Link...
Source: This Week in Virology - MP3 Edition - August 20, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 992: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses clearance of longstanding, immune-deficiency-associated, vaccine-derived poliovirus infection following remdesivir therapy for chronic SARS-CoV-2 infection, SARS-CoV-2 exposure in New York City rats, clinical characteristics and outcomes of children with SARS-CoV-2 infection during the Delta and Omicron variant-dominant periods in Korea, exhaled breath aerosol shedding of SARS-CoV-2 variants, outpatient treatment of COVID-19 and the development of long COVID over 10 months, Nirmatrelvir and the risk of post-acute sequelae of COVID-19, assessment of the risk of venous thr...
Source: This Week in Virology - MP3 Edition - March 18, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 959: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell memory responses comparable to replicating smallpox vaccines, whether the risk of still and preterm birth is affected by the timing of symptomatic SARS-CoV-2 infection during pregnancy, medical masks versus N95 respirators for...
Source: This Week in Virology - MP3 Edition - December 3, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 934: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses variant influenza virus infections: recommendations for identification, treatment, and prevention for summer and fall 2022, low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals, using the right tools at the right time for SARS-COV-2 infection, onset and window of SARS-COV-2 infectiousness and temporal correlation with symptom onset, transmission of SARS-COV-2: a review of viral, host, and environmental factors, antibody persistence and safety through 6 months after heterologous orally aerosolized Ad5-nCoV in individuals...
Source: This Week in Virology - MP3 Edition - September 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 916: COVID-19 clinical update #122 with Dr. Daniel Griffin
In COVID-19 clinical update #122, Dr. Griffin discusses vaccine availability and coverage among children, post-infection health impairments in children and adolescents, infection detection using salvia and nasopharyngeal samples, effectiveness of vaccines during delta dominance, durability of vaccine against severe outcomes, concern in the postvaccination era, infection rebound after Paxlovid & Molnupiravir, lack of improvement after adding ivermectin to standard care, duration of shedding of virus, how thromboprophylaxis reduces thromboembolism but increases major bleeding, multi-lineage neural and myelin dysregulation ca...
Source: This Week in Virology - MP3 Edition - July 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
PTSD in Family Members After COVID-19 ICU Stay, Extended Anticoagulation for Venous Thromboembolism, Screening for Eating Disorders in Adolescents and Adults, and more
Editor's Summary by Gregory Curfman, MD, Deputy Editor of JAMA, the Journal of the American Medical Association, for the March 15, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - March 15, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts
Are inflatable sleeves and medication effective to prevent deep vein thrombosis and pulmonary embolism after surgery?
The single most common, preventable cause of in-hospital death is a hospital-acquired venous thromboembolism; making this an important target for prevention when people are admitted to hospital. An updated Cochrane Review from January 2022 looks at the evidence for one of the possible interventions, which combines anti-coagulant drugs with intermittent pneumatic leg compression to prevent these blood clots. Stavros Kakkos from the University of Patras in Greece tells us more. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - February 21, 2022 Category: General Medicine Authors: Cochrane Source Type: podcasts
January 2022: Cerebral Venous Thrombosis, Acute Brain Failure, and BRASH Syndrome
Amal Mattu, MD, and colleagues tackle some tough conditions in this month’s podcast. (Source: Emergency Medicine News: SoundsBites: Q&A)
Source: Emergency Medicine News: SoundsBites: Q&A - December 30, 2021 Category: Emergency Medicine Source Type: podcasts
TWiV 842: The clot thickens
TWiV reviews the results of serum neutralization assays which show that a third vaccine dose restores neutralization of the Omicron variant, and interaction of platelet factor 4 with the adenovirus capsid, suggesting a mechanism for thrombosis with thrombocytopenia syndrome. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Third vaccine dose improves Omicron neutralization (medRxiv) ChAdOX1 interacts with PF4 (Sci Adv) Timestamps by Jolene. Thanks! Weekly Picks Brianne – Vaccine Scientists: Time’s ...
Source: This Week in Virology - MP3 Edition - December 16, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Talk Evidence - real world vaccine data, GP records and CVD
In this month's Talk Evidence, Helen Macdonald and Joe Ross are back with a wry look at the world of Evidence Based Medicine.
They give us a round up of real world data emerging to address various uncertainties about vaccinations against covid
Helen has an update on NHS Digital’s project to extract GP coding for planning of healthcare and research, and talks to Natalie Banner from Understanding Patient Data, to find o ut what the public really cares about.
Finally, as routine care must go on a clinical review on cardiovascular disease in older adults introduces us to geroscience.
Reading list
Vaccines;
Effectivene...
Source: The BMJ Podcast - September 3, 2021 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts
Talk Evidence - real world vaccine data, GP records and CVD
In this month's Talk Evidence, Helen Macdonald and Joe Ross are back with a wry look at the world of Evidence Based Medicine.
They give us a round up of real world data emerging to address various uncertainties about vaccinations against covid
Helen has an update on NHS Digital’s project to extract GP coding for planning of healthcare and research, and talks to Natalie Banner from Understanding Patient Data, to find out what the public really cares about.
Finally, as routine care must go on a clinical review on cardiovascular disease in older adults introduces us to geroscience.
Reading list
Vaccines;
Effectiveness...
Source: The BMJ Podcast - September 3, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts
Cerebral Venous Sinus Thrombosis Following Ad26.COV2.S Vaccination, Triple vs Dual Inhaler Therapy for Asthma, Transcatheter Treatment of Cardiac Valvular Disease, and more
Editor's Summary by Linda Brubaker, MD, Associate Editor of JAMA, the Journal of the American Medical Association, for the June 22, 2021 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - June 22, 2021 Category: General Medicine Authors: JAMA Network Source Type: podcasts
Talk Evidence covid-19 update - Research on vaccine safety, treatment for dementia
In this week's Talk Evidence, Joe Ross, BMJ editor and professor at Yale again joins Helen Macdonald to talk about emerging evidence on Covid-19.
They also welcome to the podcast Juan Franco, family physician in Buenos Aires, and professor at the Instituto Universitario Hospital Italiano, and new editor-in-chief of BMJ Evidence Based Medicine.
This week, the team bring you updates on;
Post-covid syndrome in individuals admitted to hospita l with covid-19 - how are people with long covid faring.
Finally published research from Scandinavia on the risk of thrombotic events after administration of the Oxford-AstraZeneca v...
Source: The BMJ Podcast - May 14, 2021 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts
