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Total 5 results found since Jan 2013.

Janssen Data at ASCO GU Support Ambition to Transform Treatment of Prostate and Bladder Cancer Through Precision Medicine and Early Intervention
RARITAN, N.J., February 13, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced plans to present more than 20 abstracts featuring seven oncology therapies from its robust portfolio and pipeline at the annual American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium, taking place in San Francisco on February 16-18. Building on more than a decade of leadership in the development of medicines for people diagnosed with GU cancers, Janssen will present data demonstrating its ambition to advance patient-centered treatment through precision medicine, real-world evidence a...
Source: Johnson and Johnson - February 13, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Peg-leg arterioles: an adaptation to chronic retinal hypoperfusion
Conclusion: Chronic severe retinal hypoperfusion due to profound carotid occlusive disease can lead to adaptive remodeling of the retinal vasculature in a pattern that closely resembles the iconic image of a pirate's peg leg.
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Treatment of the Carotid In-stent Restenosis: A Systematic Review
Conclusions: rCAS is the most common treatment for ISR, with low postoperative risk and low long-term risk. CEA is an important alternative for rCAS. PTA may be less recommended due to the relatively high long-term risks of stroke & TIA and recurrent restenosis.
Source: Frontiers in Neurology - October 4, 2021 Category: Neurology Source Type: research

Teaching NeuroImages: Radiation-associated symptomatic carotid artery disease with ipsilateral radiodermatitis
A 68-year-old man with a history of squamous cell carcinoma of the tongue treated with external beam radiation therapy in 2007 presented in 2013 with acute onset expressive aphasia and right lower facial weakness. MRI confirmed an acute infarct in the left frontal cortex. CT angiography revealed occlusion vs critical stenosis of the left internal carotid artery, new from 2007. Examination of the patient's neck revealed ipsilateral radiodermatitis (figure). Therapeutic neck irradiation has been associated with accelerated atheromatous disease, carotid artery stenosis, and increased risk of stroke.1,2 Ipsilateral radiodermat...
Source: Neurology - February 2, 2015 Category: Neurology Authors: Ehrlich, M. E., Gulvezan, T., Southerland, A. M. Tags: All Imaging, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Correspondence Radiotherapy for breast cancer, the TARGIT-A trial
Javant Vaidya and colleagues report an increased risk of non-breast cancer deaths with external beam radiotherapy (EBRT) compared with intraoperative radiotherapy, highlighting the difference in cardiac events in the two treatment groups. Although the log-rank statistics show a significant difference in non-breast cancer deaths in the EBRT group, these deaths included stroke, bowel ischaemia, and other events unrelated to breast irradiation. Therefore, the number of cardiac events are small, and to suggest that the risk of cardiac death differs between EBRT and intraoperative radiotherapy would be premature.
Source: LANCET - May 16, 2014 Category: Journals (General) Authors: Penny Mackenzie, Anthony Fyles, Caroline Chung Tags: Correspondence Source Type: research