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Therapy: Thrombolytic Therapy

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Total 1360 results found since Jan 2013.

Risk factor identification and prediction models for prolonged length of stay in hospital after acute ischemic stroke using artificial neural networks
ConclusionThe artificial neural network model achieved adequate discriminative power for predicting prolonged length of stay after acute ischemic stroke and identified crucial factors associated with a prolonged hospital stay. The proposed model can assist in clinically assessing the risk of prolonged hospitalization, informing decision-making, and developing individualized medical care plans for patients with acute ischemic stroke.
Source: Frontiers in Neurology - February 9, 2023 Category: Neurology Source Type: research

Mechanical thrombectomy for acute paradoxical cerebral embolism due to pulmonary arteriovenous malformation: A case report and review of literature
CONCLUSION: Although rare, PAVM is a treatable cause of stroke in relatively young adults; thus, it is important to keep in mind the possibility of its presence.PMID:36751447 | PMC:PMC9899467 | DOI:10.25259/SNI_987_2022
Source: Surgical Neurology International - February 8, 2023 Category: Neurosurgery Authors: Satoshi Inoue Atsushi Fujita Eiji Kurihara Takashi Sasayama Source Type: research

Effects of predictive nursing intervention on cognitive impairment and neurological function in ischemic stroke patients
ConclusionPredictive nursing intervention is beneficial to improve the effects of thrombolytic therapy in patients with ischemic stroke, which improves the neurological, cognitive and motor functions of patients, and reduces the occurrence of complications, suggesting an important clinical application value.
Source: Brain and Behavior - February 4, 2023 Category: Neurology Authors: Lianyu Xue, Jiangshan Deng, Lingyan Zhu, Feifei Shen, Jiewei Wei, Lihui Wang, Qinqin Chen, Lan Wang Tags: ORIGINAL ARTICLE Source Type: research

Predictors and long-term outcome of intracranial hemorrhage after thrombolytic therapy for acute ischemic stroke —A prospective single-center study
DiscussionOlder age, higher NIHSS, large vessel occlusion, and intra-arterial thrombolysis may correlate with ICH. The unfavorable outcome is more common in patients with ICH. Precise scoring of post-thrombolysis bleeding might be a useful tool in the evaluation of the patient's prognosis. Our findings may help to identify predictors and estimate the prognosis of ICH in patients with AIS treated with rt-PA.
Source: Frontiers in Neurology - February 1, 2023 Category: Neurology Source Type: research

Recombinant tissue plasminogen activator (rTPA) management for first onset acute Ischemic Stroke with covid -19 and non-covid -19 patients
In this study we compare the efficacy and safety of Tissue plasminogen activator (rTPA) in acute ischemic stroke (AIS) patients with or without Covid-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2023 Category: Neurology Authors: Eman M Khedr, Ahmed Abdelwarith, Gehad M Moussa, Mostafa Saber Source Type: research

Pre- and in-hospital delays in the use of thrombolytic therapy for patients with acute ischemic stroke in rural and urban Egypt
ConclusionThe limited availability of stroke-ready hospitals in rural Egypt leads to delays in stroke management, with subsequent treatment inequality of rural patients with acute stroke.
Source: Frontiers in Neurology - January 20, 2023 Category: Neurology Source Type: research

Mortality outcomes and predictors of failed thrombolysis following STEMI thrombolysis in a non-PCI capable tertiary hospital: a 5-year analysis
This study aimed to identify the incidence, mortality outcomes and predictors of FT in STEMI  pharmacological reperfusion. This single-centre retrospective cohort study analyzed data on consecutive STEMI patients who received thrombolytic therapy from 2016 to 2020 in a public tertiary hospital. Total population sampling was used in this study. Logistic regression analyses were used to asse ss independent predictors of the mortality outcomes and FT. We analyzed 941 patients with a mean age of 53.0 ± 12.2 years who were predominantly male (n = 846, 89.9%). The in-hospital mortality was 10.3% (n = 97). FT occur...
Source: Internal and Emergency Medicine - January 17, 2023 Category: Emergency Medicine Source Type: research

TMT proteomics analysis of cerebrospinal fluid from patients with cerebral venous sinus thrombosis
J Proteomics. 2023 Jan 13:104820. doi: 10.1016/j.jprot.2023.104820. Online ahead of print.ABSTRACTCVST is a type of venous stroke that mainly affects young adults with no reliable diagnostic markers and effective treatment strategies for secondary pathologies. However, the underlying pathological molecular mechanisms remain unclear. Here, we systematically analyzed the molecule profiling of the cerebrospinal fluid (CSF) in CVST patients via tandem mass tag (TMT)-based proteomics for the first time, aiming to reveal the pathogenesis and provide evidence for the diagnosis and treatment of CVST. Five CVST patients and five co...
Source: Journal of Proteomics - January 16, 2023 Category: Biochemistry Authors: Yaqi Liu Rui Ding Meng Li Weiyang Ou Xifang Zhang Weijie Yang Xiaofei Huang Huihui Chai Qiujing Wang Source Type: research

The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China
We investigated the influence of the coronavirus disease 2019 (COVID-19) pandemic on the number of patients with acute ischemic stroke who received intravenous thrombolytic therapy (ITT) in Dalian, China, in 2...
Source: BMC Neurology - January 9, 2023 Category: Neurology Authors: Xin Pan, Shubei Ma, Xiaowen Sui, Lili Xie, Furong Li, Zhengping Cheng, Li Cui and Hongling Zhao Tags: Research Source Type: research

Clinical Outcomes of Extracranial Carotid Artery-Related Stroke Eligible for Mechanical Reperfusion on Top of Per-Guidelines Thrombolytic Therapy: Analysis from a 6-Month Consecutive Patient Sample in 2 Centers
Med Sci Monit. 2022 Dec 1;28:e938549. doi: 10.12659/MSM.938549.NO ABSTRACTPMID:36451526 | DOI:10.12659/MSM.938549
Source: Medical Science Monitor - December 1, 2022 Category: Research Authors: Karolina Dzierwa Magdalena Knapik Łukasz Tekieli Adam Mazurek Ma łgorzata Urbańczyk-Zawadzka Artur Klecha Tomasz Kowalczyk Teresa Ko źmik Łukasz Wiewiórka Pawe ł Banyś Ewa W ęglarz Justyna Stefaniak Rafa ł T Nizankowski Iris Q Grunwald Piotr Mus Source Type: research

A deuterohemin peptide protects cerebral ischemia-reperfusion injury by preventing oxidative stress in vitro and in vivo
In conclusion, DhHP-3 has bioactivity of CIRI inhibition through suppression of the ROS-induced apoptosis.PMID:36442518 | DOI:10.1016/j.yexcr.2022.113432
Source: Experimental Cell Research - November 28, 2022 Category: Cytology Authors: Fanwei Meng Junfeng Ke Jinze Li Changhui Zhao Jiaqing Yan Liping Wang Source Type: research