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Prevention and treatment of stroke in patients with chronic kidney disease: an overview of evidence and current guidelines
Chronic Kidney Disease (CKD) is strongly associated with an increased risk of stroke, small vessel disease, and vascular dementia. Common vascular factors for stroke, such as hypertension, diabetes, and atrial fibrillation, are more prevalent in CKD patients, accounting for this association. However, factors unique to these patients, such as uraemia, oxidative stress, mineral and bone abnormalities, as well as dialysis-related factors are also believed to contribute to risk. Despite improvements in stroke treatment and survival in the general population, the rate of improvement in patients with CKD, especially those who ar...
Source: Kidney International - October 17, 2019 Category: Urology & Nephrology Authors: Dearbhla M. Kelly, Peter M. Rothwell Tags: Review Source Type: research
235 Association of stroke with psoriasis in end-stage renal disease patients
Previous research in the general population suggests that the inflammatory skin disease psoriasis is associated with an increased risk of vascular events, such as stroke. Thus, psoriasis may also represent a significant risk factor for stroke in dialysis patients. We queried the United States Renal Data System for incident dialysis patients between 2004 and 2015. Psoriasis was defined as having at least two ICD-9 or ICD-10 diagnosis codes. ICD codes were also used to query the outcome of interest, stroke, as well as other clinical risk factors.
Source: Journal of Investigative Dermatology - April 19, 2021 Category: Dermatology Authors: N. Siddiquee, J. Waller, S. Baer, M. Kheda, A. Mohammed, S. Padala, B. Siddiqui, L. Young, S. Tran, W. Bollag Tags: Patient Population Research Source Type: research
Incidence and prediction of ischemic stroke among atrial fibrillation patients with end-stage renal disease requiring dialysis
Renal dysfunction is a significant risk factor for ischemic stroke in atrial fibrillation (AF). However, the incidence of ischemic stroke and how to predict its occurrence among AF patients with end-stage renal disease (ESRD) are unclear.
Source: Heart Rhythm - June 18, 2014 Category: Cardiology Authors: Tze-Fan Chao, Chia-Jen Liu, Kang-Ling Wang, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Fa-Po Chung, Jo-Nan Liao, Tzeng-Ji Chen, Gregory Y.H. Lip, Shih-Ann Chen Source Type: research
Warfarin use, mortality, bleeding and stroke in haemodialysis patients with atrial fibrillation
Conclusions
In our population of HD patients with AF, the mortality is very high. OAT is not associated with increased mortality, while antiplatelet drugs are. OAT seems, on the contrary, associated with a better survival; however, it does not decrease the incidence of ischaemic stroke, whereas it increases the incidence of bleeding. Bleeding risk is lower in subjects in whom the INR is kept within the therapeutic range.
Source: Nephrology Dialysis Transplantation - February 23, 2015 Category: Urology & Nephrology Authors: Genovesi, S., Rossi, E., Gallieni, M., Stella, A., Badiali, F., Conte, F., Pasquali, S., Bertoli, S., Ondei, P., Bonforte, G., Pozzi, C., Rebora, P., Valsecchi, M. G., Santoro, A. Tags: Intra- and Extracorporeal Treatments of Kidney Failure Source Type: research
Risk of major cardiovascular events in patients with hemodialysis or peritoneal dialysis with special reference to stroke
Kim et al. determined the incidence rates of major adverse cardiac and cerebrovascular events (MACCE) and compared several types of events between hemodialysis (HD) patients and peritoneal dialysis (PD) patients [1]. The authors handled 22,892 HD patients and 7,387 PD patients in Korea by intention-to-treat method, and median follow-up period was 21.5 months. The risk of several cardiac events in PD patients was significantly higher than that in HD patients. In contrast, the incidence rate of non-fatal hemorrhagic stroke in HD patients showed significantly higher than that in PD patients, and there was no significant diffe...
Source: International Journal of Cardiology - September 21, 2015 Category: Cardiology Authors: Tomoyuki Kawada Source Type: research
Cardiovascular and Stroke Risk in Japanese Hemodialysis Patients With Atrial Fibrillation
Abstract
Atrial fibrillation is one of the most common arrhythmias in hemodialysis patients. We evaluated its clinical outcomes among hemodialysis patients with atrial fibrillation in Japan. Using data derived from the Japanese Dialysis Outcomes and Practice Patterns Study, we analyzed backgrounds and outcomes among hemodialysis patients with and without atrial fibrillation in Japan. Among 7002 hemodialysis patients, the prevalence of atrial fibrillation was 5.7% and the incidence was 0.2 per 100 patient‐years. Atrial fibrillation was independently associated with all‐cause mortality (hazard ratio, 1.32; 95% confidence...
Source: Therapeutic Apheresis and Dialysis - September 30, 2016 Category: Hematology Authors: Jumpei Hasegawa, Brian Bieber, Maria Larkina, Bruce M. Robinson, Sachiko Wakai, Tadao Akizawa, Akira Saito, Shunichi Fukuhara, Takashi Akiba Tags: Original Article Source Type: research
Low-dose Apixaban May Be Safe Anti-stroke Option for Dialysis Patients Low-dose Apixaban May Be Safe Anti-stroke Option for Dialysis Patients
Low-dose apixaban achieves blood levels that appear to be safe and might be a “ reasonable alternative ” to warfarin for preventing stroke in patients with atrial fibrillation who are on hemodialysis, new research suggests.Reuters Health Information
Source: Medscape Critical Care Headlines - March 24, 2017 Category: Intensive Care Tags: Neurology & Neurosurgery News Source Type: news
ESRD After Heart Failure, Myocardial Infarction, or Stroke in Type 2 Diabetic Patients With CKD
Conclusions Most ESRD cases occurred in individuals without intercurrent CV events who had lower eGFRs than individuals with intercurrent CV events, but similar post-ESRD mortality. Nevertheless, intercurrent CV events, particularly heart failure, are strongly associated with risk for ESRD. These findings underscore the need for kidney-specific therapies in addition to treatment of CV risk factors to lower ESRD incidence in diabetes.
Source: American Journal of Kidney Diseases - June 7, 2017 Category: Urology & Nephrology Source Type: research
Reverse epidemiology of elevated blood pressure among chronic hemodialysis black patients with stroke: a historical cohort study
The objective of this study was to assess the extent of stroke in chronic hemodialysis patients.
Source: BMC Nephrology - August 30, 2017 Category: Urology & Nephrology Authors: Yannick Nlandu, Fran çois Lepira, Jean-Robert Makulo, Yannick Engole, Ernest Sumaili, Marie-Noelle Wameso, Vieux Mokoli, Jeannine Luse, Augustin Longo, Chantal Zinga, Pierre Akilimali, Aliocha Nkodila, Mélanie Bavassa, François Kajingulu, Justine Bukab Tags: Research article Source Type: research
Hemoglobin Concentration and Stroke Risk in Hemodialysis Hemoglobin Concentration and Stroke Risk in Hemodialysis
Might low hemoglobin concentrations contribute to the risk for hemorrhagic or ischemic stroke among hemodialysis patients?Nephrology Dialysis Transplantation
Source: Medscape Today Headlines - June 13, 2018 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news
Renal Replacement Modality and Stroke Risk in ESRD Renal Replacement Modality and Stroke Risk in ESRD
How does each particular renal replacement modality for ESRD impact the risk for stroke?Nephrology Dialysis Transplantation
Source: Medscape Today Headlines - October 5, 2018 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news
Low Incidence of Death and Renal Failure in United States Military Service Members Hospitalized with Exertional Heat Stroke: A Retrospective Cohort Study.
CONCLUSION: EHS is aggressively identified and treated in U.S. Military Treatment Facilities. Mortality and morbidity were strikingly low.
PMID: 32074343 [PubMed - in process]
Source: Military Medicine - February 21, 2020 Category: International Medicine & Public Health Tags: Mil Med Source Type: research
Composite Dialysis, Paralysis, Stroke, or Mortality After Endovascular Aortic Interventions in the Society for Vascular Surgery Vascular Quality Initiative
Thoracoabdominal aortic aneurysm life-altering events, which include a combination of permanent dialysis, permanent spinal cord ischemia, stroke, and/or death, have devastating effects after complex endovascular repair. However, the occurrence of these life-altering events after endovascular abdominal aortic aneurysm repair (EVAR) and thoracic endovascular aortic repair (TEVAR) has not been studied. Therefore, we examined the effects of procedural and anatomic characteristics on a composite outcome of postoperative dialysis, stroke, paralysis, and/or mortality after any endovascular aortic repair.
Source: Journal of Vascular Surgery - August 24, 2021 Category: Surgery Authors: Priya Patel, Christina Marcaccio, Livia de Guerre, Nicholas J. Swerdlow, Thomas F. O'Donnell, Sara L. Zettervall, Virendra I. Patel, Marc L. Schermerhorn Tags: IP: Interactive Poster Session Source Type: research
Prognostic factors for acute ischemic stroke in patients undergoing hemodialysis
ConclusionsAlong with neurological severity, dialysis vintage, intradialytic hypotension, and diabetic nephropathy could worsen the prognosis of patients with AIS undergoing hemodialysis.
Source: Clinical and Experimental Nephrology - November 12, 2021 Category: Urology & Nephrology Source Type: research
