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Specialty: Cardiology

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Total 25977 results found since Jan 2013.

Is Hypertension Diagnostic Testing and Diagnosis Associated with Psychological Distress?
CONCLUSIONS: The hypertension diagnostic process did not lead to short-term or intermediate-term changes in self-reported HRQOL. However, BP-related worry increased short-term and persisted at 6 months among individuals with a new hypertension diagnosis. Results warrant validation in more representative populations and additional exploration of the impacts of this worry on psychological well-being and hypertension control.PMID:37688515 | DOI:10.1093/ajh/hpad083
Source: American Journal of Hypertension - September 9, 2023 Category: Cardiology Authors: B B Green M L Anderson J B McClure K Ehrlich Y N Hall L Hansell C Hsu K L Margolis S A Munson M J Thompson Source Type: research

Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility
AbstractThe ketone body 3-hydroxybutyrate (3-OHB) increases cardiac output and myocardial perfusion without affecting blood pressure in humans, but the cardiovascular sites of action remain obscure. Here, we test the hypothesis in rats that 3-OHB acts directly on the heart to increase cardiac contractility and directly on blood vessels to lower systemic vascular resistance. We investigate effects of 3-OHB on (a) in vivo hemodynamics using echocardiography and invasive blood pressure measurements, (b) isolated perfused hearts in Langendorff systems, and (c) isolated arteries and veins in isometric myographs. We compare Na-3...
Source: Basic Research in Cardiology - September 9, 2023 Category: Cardiology Source Type: research

Blocking interleukin-6 Trans-Signaling in AF: Promises and Challenges
Atrial fibrillation (AF) stands as the most prevalent cardiovascular disease, posing significant risks of stroke, heart failure, and other complications that contribute to morbidity and mortality. While traditionally research on AF has primarily focused on electrophysiological components like ionic currents and the Ca2+ handling system, treatment strategies have mainly revolved around the rate-limiting beta-blockers and Ca2+ channel blockers, or rhythm-control methods such as cardioversion, antiarrhythmics, and catheter ablation.
Source: Heart Rhythm - September 9, 2023 Category: Cardiology Authors: Enrique Martinez, Na Li Source Type: research

Associations of Apixaban Dose With Safety and Effectiveness Outcomes in Patients With Atrial Fibrillation and Severe Chronic Kidney Disease
CONCLUSIONS: Compared with 2.5 mg, use of 5 mg apixaban was associated with a higher risk of bleeding in patients with atrial fibrillation and severe chronic kidney disease, with no difference in the risk of stroke/systemic embolism or death, supporting the apixaban dosing recommendations on the basis of kidney function by the European Medicines Agency, which differ from those issued by the US Food and Drug Administration.PMID:37681341 | DOI:10.1161/CIRCULATIONAHA.123.065614
Source: Circulation - September 8, 2023 Category: Cardiology Authors: Yunwen Xu Alex R Chang Lesley A Inker Mara McAdams-DeMarco Morgan E Grams Jung-Im Shin Source Type: research

Cervical dumbbell-type tumor spontaneously shrinking following an ischemic stroke
CONCLUSION: Here, we report on a 57-year-old man with cervical MR images revealing that a cervical dumbbell schwannoma was progressively compressing both the spinal cord and the right vertebral artery. However, following a cerebral infarction, the tumor underwent spontaneous shrinkage over the next 4 years, thus relieving the compression.PMID:37680907 | PMC:PMC10481817 | DOI:10.25259/SNI_613_2023
Source: Atherosclerosis - September 8, 2023 Category: Cardiology Authors: Kota Nakajima Yoshinori Maki Toshinari Kawasaki Motohiro Takayama Source Type: research

Quantification of carotid plaque composition with a multi-contrast atherosclerosis characterization (MATCH) MRI sequence
CONCLUSION: MATCH images can be used to quantify plaque components such as LRNC and IPH but not for calcifications. Although MATCH images showed a lower mean image quality score, short scan time and inherent co-registration are significant advantages.PMID:37680565 | PMC:PMC10481960 | DOI:10.3389/fcvm.2023.1227495
Source: Atherosclerosis - September 8, 2023 Category: Cardiology Authors: Mohamed Kassem Kelly P H Nies Ellen Boswijk Jochem van der Pol Mueez Aizaz Marion J J Gijbels Debiao Li Jan Bucerius Werner H Mess Joachim E Wildberger Robert J van Oostenbrugge Rik P M Moonen Zhaoyang Fan M Eline Kooi Source Type: research

Circulating Endothelial Progenitor and Mesenchymal Stromal Cells as Biomarkers for Monitoring Disease Status and Responses to Exercise
Rev Cardiovasc Med. 2022 Dec 2;23(12):396. doi: 10.31083/j.rcm2312396.ABSTRACTNoncommunicable chronic diseases, such as obesity, cardiovascular disease (CVD), and type 2 diabetes (T2D), pose significant health challenges globally. Important advances have been made in the understanding of the pathophysiologal mechanisms and treatment of noncommunicable diseases in recent years. Lack of physical activity is a primary contributor to many noncommunicable diseases including metabolic syndrome, T2D, CVD, and obesity. Certain diabetes medications and non-pharmaceutical interventions, such as physical activity and exercise, are sh...
Source: Reviews in Cardiovascular Medicine - September 8, 2023 Category: Cardiology Authors: Jared M Gollie Sabyasachi Sen Source Type: research

Associations of Apixaban Dose With Safety and Effectiveness Outcomes in Patients With Atrial Fibrillation and Severe Chronic Kidney Disease
CONCLUSIONS: Compared with 2.5 mg, use of 5 mg apixaban was associated with a higher risk of bleeding in patients with atrial fibrillation and severe chronic kidney disease, with no difference in the risk of stroke/systemic embolism or death, supporting the apixaban dosing recommendations on the basis of kidney function by the European Medicines Agency, which differ from those issued by the US Food and Drug Administration.PMID:37681341 | DOI:10.1161/CIRCULATIONAHA.123.065614
Source: Circulation - September 8, 2023 Category: Cardiology Authors: Yunwen Xu Alex R Chang Lesley A Inker Mara McAdams-DeMarco Morgan E Grams Jung-Im Shin Source Type: research

Circulating Endothelial Progenitor and Mesenchymal Stromal Cells as Biomarkers for Monitoring Disease Status and Responses to Exercise
Rev Cardiovasc Med. 2022 Dec 2;23(12):396. doi: 10.31083/j.rcm2312396.ABSTRACTNoncommunicable chronic diseases, such as obesity, cardiovascular disease (CVD), and type 2 diabetes (T2D), pose significant health challenges globally. Important advances have been made in the understanding of the pathophysiologal mechanisms and treatment of noncommunicable diseases in recent years. Lack of physical activity is a primary contributor to many noncommunicable diseases including metabolic syndrome, T2D, CVD, and obesity. Certain diabetes medications and non-pharmaceutical interventions, such as physical activity and exercise, are sh...
Source: Reviews in Cardiovascular Medicine - September 8, 2023 Category: Cardiology Authors: Jared M Gollie Sabyasachi Sen Source Type: research

Cervical dumbbell-type tumor spontaneously shrinking following an ischemic stroke
CONCLUSION: Here, we report on a 57-year-old man with cervical MR images revealing that a cervical dumbbell schwannoma was progressively compressing both the spinal cord and the right vertebral artery. However, following a cerebral infarction, the tumor underwent spontaneous shrinkage over the next 4 years, thus relieving the compression.PMID:37680907 | PMC:PMC10481817 | DOI:10.25259/SNI_613_2023
Source: Atherosclerosis - September 8, 2023 Category: Cardiology Authors: Kota Nakajima Yoshinori Maki Toshinari Kawasaki Motohiro Takayama Source Type: research

Quantification of carotid plaque composition with a multi-contrast atherosclerosis characterization (MATCH) MRI sequence
CONCLUSION: MATCH images can be used to quantify plaque components such as LRNC and IPH but not for calcifications. Although MATCH images showed a lower mean image quality score, short scan time and inherent co-registration are significant advantages.PMID:37680565 | PMC:PMC10481960 | DOI:10.3389/fcvm.2023.1227495
Source: Atherosclerosis - September 8, 2023 Category: Cardiology Authors: Mohamed Kassem Kelly P H Nies Ellen Boswijk Jochem van der Pol Mueez Aizaz Marion J J Gijbels Debiao Li Jan Bucerius Werner H Mess Joachim E Wildberger Robert J van Oostenbrugge Rik P M Moonen Zhaoyang Fan M Eline Kooi Source Type: research