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Total 10343 results found since Jan 2013.

First Clinical Evidence of Neuroprotection in Acute Stroke? First Clinical Evidence of Neuroprotection in Acute Stroke?
A new potential neuroprotectant has been found to be beneficial for patients with ischemic stroke undergoing thrombectomy in the ESCAPE-NA1 trial, but only for those not receiving thrombolysis.Medscape Medical News
Source: Medscape Cardiology Headlines - February 20, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

TNK Dose in Large-Vessel Stroke: 0.25 mg/kg Is Sufficient TNK Dose in Large-Vessel Stroke: 0.25 mg/kg Is Sufficient
New data from a second EXTEND-IA TNK (tenecteplase) trial clarify the optimum dose of the bolus thrombolytic for use in ischemic stroke, for which enthusiasm is growing.Medscape Medical News
Source: Medscape Cardiology Headlines - February 20, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Association of Small Dense Low-Density Lipoprotein Cholesterol with Stroke Risk, Severity and Prognosis.
CONCLUSIONS: Elevated levels of sdLDL-C were associated with a higher prevalence of AIS, especially in non-cardioembolic stroke subtypes. After adjustment for other risk factors, sdLDL-C was found to be an independent risk factor for AIS. Also, sdLDL-C level was strongly associated with AIS severity and poor functional outcomes. Logistic regression models for AIS risk and prognosis prediction were established to help clinicians provide better prevention for high-risk subjects and monitor their prognosis. PMID: 32062644 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - February 20, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Mechanical Thrombectomy for Posterior Circulation Occlusion: A Comparison of Outcomes with the Anterior Circulation Occlusion - A Meta-Analysis.
CONCLUSIONS: We found that the outcomes of MT for patients with PCO were poorer than with ACO. On the other hand, MT appears to have lower rates of sICH and to increase successful recanalization. Given the high recanalization rate, MT may serve as an adjunct to standard treatment. The key point to improve outcomes is recognizing reliable factors associated with futile recanalization and optimizing the results of MT. But in view of the different characteristics of posterior circulation stroke and anterior circulation stroke, the results are far from robust. PMID: 32062629 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - February 20, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Oral Anticoagulants and Antiplatelet Agents in Atrial Fibrillation Patients with Concomitant Critical Limb Ischemia: A nationwide cohort study
ConclusionsDOAC was associated with a significantly lower risk of composite net-clinical-benefit outcome than either warfarin or APT in AF patients with concomitant CLI. Further prospective study is necessary to validate the findings in the future.
Source: Canadian Journal of Cardiology - February 19, 2020 Category: Cardiology Source Type: research

Late Clinical Outcomes of LAmbre versus Amplatzer Occluders for Left Atrial Appendage Closure
ConclusionIn the presented report, in patients with nonvalvular atrial fibrillation the LAmbre offered similar long ‐term efficacy and safety in comparison to Amplatzer devices.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - February 19, 2020 Category: Cardiology Authors: Steffen Schnupp, Xiao ‐xia Liu, Eric Buffle, Steffen Gloekler, Yamen Mohrez, Mohammad Cheikh‐Ibrahim, Wasim Allakkis, Johannes Brachmann, Jai‐Wun Park, Caroline Kleinecke Tags: ORIGINAL ARTICLE Source Type: research

AHA News: Race and Gender May Tip the Scales on Traditional Stroke Risk Factors
Title: AHA News: Race and Gender May Tip the Scales on Traditional Stroke Risk FactorsCategory: Health NewsCreated: 2/18/2020 12:00:00 AMLast Editorial Review: 2/19/2020 12:00:00 AM
Source: MedicineNet Heart General - February 19, 2020 Category: Cardiology Source Type: news

AHA News: Father's Fatal Stroke a 'Wake-Up Call' for Sons
Title: AHA News: Father's Fatal Stroke a 'Wake-Up Call' for SonsCategory: Health NewsCreated: 2/18/2020 12:00:00 AMLast Editorial Review: 2/19/2020 12:00:00 AM
Source: MedicineNet Heart General - February 19, 2020 Category: Cardiology Source Type: news

Impact of Atrial Fibrillation on In-Hospital Mortality and Thromboembolic Complications after Left Ventricular Assist Device Implantation
AbstractThe association between atrial fibrillation (AF) and thromboembolic (TE) complications in left ventricular assist device (LVAD) recipients is controversial, and there is paucity of large-scale data evaluating the impact of AF on early outcomes after device implantation. Using the National Inpatient Sample, we identified hospitalizations where patients underwent LVAD implantation from 2010 to 2015. Multivariate logistic regression was used to evaluate the association of AF on in-hospital outcomes. A total of 18,378 patients (41.7% with AF) underwent LVAD implantation. Patients with AF were older (59.9 vs. 54.0  yea...
Source: Journal of Cardiovascular Translational Research - February 19, 2020 Category: Cardiology Source Type: research

Is Sunny Outlook the Best Rx for Stroke Recovery?
Title: Is Sunny Outlook the Best Rx for Stroke Recovery?Category: Health NewsCreated: 2/13/2020 12:00:00 AMLast Editorial Review: 2/18/2020 12:00:00 AM
Source: MedicineNet Heart General - February 18, 2020 Category: Cardiology Source Type: news

AHA News: Diabetes, Alzheimer's Together Might Increase Stroke Severity
Title: AHA News: Diabetes, Alzheimer's Together Might Increase Stroke SeverityCategory: Health NewsCreated: 2/17/2020 12:00:00 AMLast Editorial Review: 2/18/2020 12:00:00 AM
Source: MedicineNet Heart General - February 18, 2020 Category: Cardiology Source Type: news

Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study.
CONCLUSIONS: In this population-based study, aromatase inhibitors were associated with increased risks of heart failure and cardiovascular mortality compared with tamoxifen. There were also trends toward increased risks, although nonsignificant, of myocardial infarction and ischemic stroke. The increased risk of cardiovascular events associated with aromatase inhibitors should be balanced with their favorable clinical benefits compared with tamoxifen. PMID: 32065766 [PubMed - in process]
Source: Circulation - February 18, 2020 Category: Cardiology Authors: Khosrow-Khavar F, Filion KB, Bouganim N, Suissa S, Azoulay L Tags: Circulation Source Type: research

Women's Participation in Cardiovascular Clinical Trials From 2010 to 2017.
CONCLUSIONS: Among cardiovascular trials in the current decade, men still predominate overall, but the representation of women varies with disease and trial characteristics, and has improved in stroke and heart failure trials. PMID: 32065763 [PubMed - in process]
Source: Circulation - February 18, 2020 Category: Cardiology Authors: Jin X, Chandramouli C, Allocco B, Gong E, Lam CSP, Yan LL Tags: Circulation Source Type: research

Oxidized low-density lipoprotein (LDL) and LDL cholesterol are associated with outcomes of minor stroke and TIA
Low-density lipoprotein (LDL) and oxidized low-density lipoprotein (oxLDL) levels are thought to be related to recurrent stroke. However, the joint association of circulating LDL and oxLDL levels with the outcomes of acute minor ischemic stroke and transient ischemic attack (TIA) remains unclear. The goal of the study was to evaluate whether LDL and oxLDL have a combined effect on outcomes of acute minor stroke and TIA.
Source: Atherosclerosis - February 18, 2020 Category: Cardiology Authors: Anxin Wang, Liye Dai, Nan Zhang, Jinxi Lin, Guojuan Chen, Yingting Zuo, Hao Li, Yilong Wang, Xia Meng, Yongjun Wang Source Type: research

Anticoagulation for atrial fibrillation patients with the CHA2DS2-VASc score =1 (beyond sex).
Authors: Xie X, Li T Abstract Objective: We investigated the risk of ischaemic stroke in patients with 1 another stroke risk factor (i.e. CHA2DS2-VASc score =1 [males] or 2 [females]) and the impact of different component risk factors.Methods: Database were collected from two hospitals in the city of Hohhot in china. Among 3148 Nonvalvular AF patients not on antiplatelet or anticoagulant therapy, we evaluated males with a CHA2DS2-VASc score of 1 and females with a CHA2DS2-VASc score of 2. The clinical endpoint was the occurrence of ischaemic stroke.Results: Among 546 AF male patients with a CHA2DS2-VASc score of ...
Source: Acta Cardiologica - February 16, 2020 Category: Cardiology Tags: Acta Cardiol Source Type: research

Uninterrupted anticoagulation during catheter ablation for atrial fibrillation: no difference in major bleeding and stroke between direct oral anticoagulants and vitamin K antagonists in an updated meta-analysis of randomised controlled trials.
Conclusion: Our meta-analysis suggests that uninterrupted DOAC is not superior to VKA in patients undergoing catheter ablation of AF with comparable rates of major bleeding and stroke. PMID: 32056498 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - February 16, 2020 Category: Cardiology Tags: Acta Cardiol Source Type: research

Relationship between brachial flow-mediated dilation and carotid intima-media thickness in patients with coronary artery disease.
CONCLUSIONS: Brachial FMD and carotid IMT would be different in clinical significance as a surrogate marker for pathophysiology of atherosclerotic disease. PMID: 32057215 [PubMed - as supplied by publisher]
Source: International Angiology - February 16, 2020 Category: Cardiology Tags: Int Angiol Source Type: research

Stroke in pulmonary hypertension: Is it predictable or preventable?
Dear Editor,
Source: International Journal of Cardiology - February 14, 2020 Category: Cardiology Authors: Lingdan Chen, Wenjun He, Fei Liu, Tao Wang Tags: Letter to the Editor Source Type: research

AHA News: Stroke Rates Down for Mexican Americans, Up for White Adults
Title: AHA News: Stroke Rates Down for Mexican Americans, Up for White AdultsCategory: Health NewsCreated: 2/13/2020 12:00:00 AMLast Editorial Review: 2/14/2020 12:00:00 AM
Source: MedicineNet Heart General - February 14, 2020 Category: Cardiology Source Type: news

Young Black Adults More Prone to Stroke, but Don't Know It
Title: Young Black Adults More Prone to Stroke, but Don't Know ItCategory: Health NewsCreated: 2/13/2020 12:00:00 AMLast Editorial Review: 2/14/2020 12:00:00 AM
Source: MedicineNet Heart General - February 14, 2020 Category: Cardiology Source Type: news

Transcatheter treatment of native aortic valve regurgitation: Results from an international registry using the transfemoral ACURATE neo valve
ConclusionsThis multicenter study suggests good feasibility and early safety of transfemoral TAVR with the self-expandable ACURATE neo device in patients with severe NAVR refused for surgery. Rates of moderate PVL, new pacemaker implantation and need for a second valve were higher than those reported for TAVR in aortic stenosis.
Source: IJC Heart and Vasculature - February 13, 2020 Category: Cardiology Source Type: research

Impact of left ventricular ejection fraction on clinical outcomes after left main coronary artery revascularization: results from the randomized EXCEL trial
ConclusionIn the EXCEL trial, the composite rate of death, stroke or myocardial infarction at 3  years was significantly higher in patients with HFrEF compared with HFmrEF or preserved LVEF, driven by an increased rate of all‐cause death. No significant differences after PCI vs. CABG were observed among patients with HFrEF, HFmrEF and preserved LVEF. Longer‐term follow‐up could provide important insights on differences in clinical outcomes that might emerge over time.Clinical Trial Registration:ClinicalTrials.gov IDNCT01205776.
Source: European Journal of Heart Failure - February 13, 2020 Category: Cardiology Authors: Daniel J.F.M. Thuijs, Milan Milojevic, Gregg W. Stone, John D. Puskas, Patrick W. Serruys, Joseph F. Sabik, Ovidiu Dressler, Aaron Crowley, Stuart J. Head, A. Pieter Kappetein Tags: Research Article Source Type: research

Stroke Risk Tied to Diabetic Retinopathy May Not Be Modifiable Stroke Risk Tied to Diabetic Retinopathy May Not Be Modifiable
New evidence confirming the association between diabetic retinopathy and elevated stroke risk also demonstrates that common clinical interventions to lower risk may not help.Medscape Medical News
Source: Medscape Cardiology Headlines - February 13, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Shingles Vaccine Bonus: Reduced Risk of Stroke?
Title: Shingles Vaccine Bonus: Reduced Risk of Stroke?Category: Health NewsCreated: 2/12/2020 12:00:00 AMLast Editorial Review: 2/13/2020 12:00:00 AM
Source: MedicineNet Heart General - February 13, 2020 Category: Cardiology Source Type: news

Growing Up in U.S. 'Stroke Belt' Bad for the Brain Later in Life
Title: Growing Up in U.S. 'Stroke Belt' Bad for the Brain Later in LifeCategory: Health NewsCreated: 2/12/2020 12:00:00 AMLast Editorial Review: 2/13/2020 12:00:00 AM
Source: MedicineNet Heart General - February 13, 2020 Category: Cardiology Source Type: news

Even After Stroke, Many Smokers Still Light Up
Title: Even After Stroke, Many Smokers Still Light UpCategory: Health NewsCreated: 2/13/2020 12:00:00 AMLast Editorial Review: 2/13/2020 12:00:00 AM
Source: MedicineNet Heart General - February 13, 2020 Category: Cardiology Source Type: news

Choosing the right therapy for a patient with asymptomatic carotid stenosis.
Authors: Bogiatzi C, Azarpazhooh MR, Spence JD Abstract Introduction: Most patients with asymptomatic carotid stenosis (ACS) now have a lower risk with intensive medical therapy than with stenting (CAS) or endarterectomy (CEA); the annual risk of stroke or death with intensive medical therapy is ~ 0.5%, vs. a periprocedural risk with CAS of ~ 2.5-4.1% with CAS, and ~ 1.4-1.8% with CEA. The excess risk of CAS is greater in older patients.Areas covered: Discussed are the need for intensive medical therapy, the nature of intensive medical therapy, approaches to identifying the few patients with ACS who could benefit f...
Source: Expert Review of Cardiovascular Therapy - February 12, 2020 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Impact of left ventricular ejection fraction on clinical outcomes after left main coronary artery revascularization: results from the randomized EXCEL trial
ConclusionIn the EXCEL trial, the composite rate of death, stroke or myocardial infarction at 3  years was significantly higher in patients with HFrEF compared with HFmrEF or preserved LVEF, driven by an increased rate of all‐cause death. No significant differences after PCI vs. CABG were observed among patients with HFrEF, HFmrEF and preserved LVEF. Longer‐term follow‐up could provide important insights on differences in clinical outcomes that might emerge over time.Clinical Trial Registration:ClinicalTrials.gov IDNCT01205776.
Source: European Journal of Heart Failure - February 11, 2020 Category: Cardiology Authors: Daniel J.F.M. Thuijs, Milan Milojevic, Gregg W. Stone, John D. Puskas, Patrick W. Serruys, Joseph F. Sabik, Ovidiu Dressler, Aaron Crowley, Stuart J. Head, A. Pieter Kappetein Tags: Research Article Source Type: research

Evaluation of the Safety and Effectiveness of Direct-Acting Oral Anticoagulants in Patients with Atrial Fibrillation and Coexisting Valvular Heart Disease
ConclusionsIn patients with AF and VHD, rates of major bleeding were similar among the DOACs and valve types; however, more patients receiving dabigatran experienced SSE. Further studies are needed to validate these findings.
Source: American Journal of Cardiovascular Drugs - February 11, 2020 Category: Cardiology Source Type: research

Transcatheter aortic valve replacement for patients with severe bicuspid aortic stenosis
ConclusionsThis initial experience suggests TAVR can be safely performed in patients with BAV achieving similar short-term procedural and clinical outcomes when compared with patients with TAV.Condensed AbstractThe outcomes of 50 patients (8.8%) with bicuspid aortic stenosis (BAV) undergoing TAVR were compared with those of 517 patients (91.2%) with trileaflet aortic valve (TAV) stenosis. Patients with BAV were younger, had higher prevalence of COPD, lower prevalence of CAD, higher BMI and lower STS score. Major complications were similar between the groups, including stroke (2.0% vs. 1.5, P = .567), 30-day all-c...
Source: American Heart Journal - February 9, 2020 Category: Cardiology Source Type: research

Association of Postoperative Complications and Outcomes Following Coronary Artery Bypass Grafting
ConclusionsPostoperative complications are associated with an increased risk of both early and late mortality and all-cause rehospitalization, particularly during the “value” window within 90 days of CABG. These findings underscore the need to develop avoidance strategies as well as cost-adjustment methods for each of these complications.
Source: American Heart Journal - February 9, 2020 Category: Cardiology Source Type: research

Impact of creatinine clearance on clinical outcomes in elderly atrial fibrillation patients receiving apixaban: J-ELD AF registry sub-analysis
ConclusionsThe incidence of events in each CCr value group was comparable for stroke or systemic embolism and bleeding requiring hospitalization, and significantly higher for total deaths and cardiovascular deaths only in the CCr 15–29 mL/min group, in Japanese non-valvular AF patients aged ≥75 years.
Source: American Heart Journal - February 9, 2020 Category: Cardiology Source Type: research

Blood Pressure at Six Months after Acute Myocardial Infarction and Outcomes at Two Years: The Perils Associated with Excessively Low Blood Pressures
ConclusionsLow blood pressure achieved with beta-blocker and renin-angiotensin-aldosterone blocker at 6-month was associated with an increased risk of all-cause mortality independently of confounding factors in patients with AMI. This finding suggests that caution should be taken for patients with AMI who use blood pressure-lowering treatments.
Source: Canadian Journal of Cardiology - February 9, 2020 Category: Cardiology Source Type: research

Cochrane Corner: Perioperative beta-blockers for preventing surgery-related mortality and morbidity
In conclusion, perioperative use of beta-blockers appears overall to be beneficial in cardiac surgery. However, in non-cardiac surgery the substantial reduction in rhythm disturbances and AMI appears to be offset by an increase in mortality and stroke, and so the systematic use of beta-blockers in this setting is not recommended.ResumoOs resultados de ensaios clínicos aleatorizados relativos à utilização de betabloqueantes no período perioperatório de cirurgia cardíaca e não cardíaca têm sido controversos. Esta revisão sistemática da Cochrane avaliou o impacto dessa intervenção na mortalidade e eventos cardi...
Source: Revista Portuguesa de Cardiologia - February 8, 2020 Category: Cardiology Source Type: research

Compared with matched controls, patients with postoperative atrial fibrillation (POAF) have increased long-term AF after CABG, and POAF is further associated with increased ischemic stroke, heart failure and mortality even after adjustment for AF
ConclusionsPatients with POAF after CABG had three times the incidence of long-term AF compared with both non-POAF patients and matched controls. POAF was associated with long-term ischemic stroke, heart failure, and corresponding mortality even after adjustment for AF during follow-up. The increased overall mortality was partly explained by morbidities associated with POAF.Graphic abstract
Source: Clinical Research in Cardiology - February 8, 2020 Category: Cardiology Source Type: research

Association of increased arterial stiffness with diastolic dysfunction in ischemic stroke patients: the Norwegian Stroke in the Young Study
Background: Young and middle-aged ischemic stroke survivors have a high prevalence of hypertension, increased arterial stiffness and abnormal left ventricular (LV) geometry, which all are associated with the presence of LV diastolic dysfunction. However, the prevalence and covariates of diastolic dysfunction in these patients have not been reported. Objectives: To explore diastolic dysfunction in ischemic stroke patients aged 15–60 years included in the Norwegian Stroke in the Young Study. Methods: Data from 260 patients with acute ischemic stroke was analyzed. Diastolic dysfunction was assessed by combining tran...
Source: Journal of Hypertension - February 7, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Patent foramen ovale, role of antiplatelet therapy alone or anticoagulant therapy alone versus device closure for cryptogenic stroke: A review of literature and current recommendations.
Authors: Nagarajarao HS, Ojha CP, Kedar A, Mukherjee D Abstract Cryptogenic stroke and its relation to the Patent foramen ovale (PFO) is a long debated topic. Recent clinical trials have unequivocally established the relationship between cryptogenic strokes and paradoxical embolism across the PFO. This slit like communication exists in everyone before birth, but most often closes shortly after birth. PFO may persist as a narrow channel of communication between right and left atria in approximately 25-27% of adults [1, 2]. In this review we examine the clinical relevance of the PFO with analysis of latest trials eva...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - February 6, 2020 Category: Cardiology Tags: Cardiovasc Hematol Agents Med Chem Source Type: research

Implementation of Best Practices—Developing and Optimizing Regional Systems of Stroke Care: Design and Methodology
Publication date: April 2020Source: American Heart Journal, Volume 222Author(s): Matthew E Ehrlich, Brad J Kolls, Mayme Roettig, Lisa Monk, Shreyansh Shah, Ying Xian, James G Jollis, Christopher B Granger, Carmelo GraffagninoAbstractThe AHA Guidelines recommend developing multi-tiered systems for the care of patients with acute stroke.1 An ideal stroke system of care should ensure that all patients receive the most efficient and timely care, regardless of how they first enter or access the medical care system. Coordination among the components of a stroke system is the most challenging but most essential aspect of any syst...
Source: American Heart Journal - February 4, 2020 Category: Cardiology Source Type: research

Blood Pressure Key to Good Outcomes in Stroke Thrombectomy Blood Pressure Key to Good Outcomes in Stroke Thrombectomy
Both low and high levels of blood pressure during endovascular treatment for acute ischemic stroke are associated with poor functional outcome, a new study suggests.Medscape Medical News
Source: Medscape Cardiology Headlines - February 4, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Investigation of Computed-Tomography Based Predictors of Acute Stroke Related to Transcatheter Aortic Valve Replacement: Aortic Wall Plaque Thickness Might be a Predictive Parameter of Stroke.
CONCLUSION: Aortic wall plaque thickness measured by contrast-enhanced CT might be a predictive parameter of strokes that occur within 48 hours after TAVR. PMID: 32005786 [PubMed - in process]
Source: The Journal of Invasive Cardiology - February 3, 2020 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

New approach to the prevention of stroke in patients with non-valvular fibrillation in hemodialysis: percutaneous closure of left atrial appendage.
PMID: 31996870 [PubMed - in process]
Source: Archivos de Cardiologia de Mexico - February 1, 2020 Category: Cardiology Authors: Torres-Saura F, Romero-Vazquiánez M, Pérez-Berbel P, Rosa EC, Diez-Ojea B, Arroyo-Úcar E Tags: Arch Cardiol Mex Source Type: research

Aspirin plus clopidogrel versus aspirin Mono-Therapy for ischemic stroke.
Authors: Kumar A, Shariff M, Doshi R PMID: 31994939 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - January 30, 2020 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association.
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, healthcare administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions. PMID: 31992061 [PubMed - as supplied by publisher]
Source: Circulation - January 29, 2020 Category: Cardiology Authors: Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longeneck Tags: Circulation Source Type: research

Atrial premature activity detected after an ischaemic stroke unveils atrial myopathy.
CONCLUSIONS: After an ischaemic stroke or a transient ischaemic attack, excessive APCs are associated with LA remodelling. Thus, LA dilatation and dysfunction reflect early LA myopathy, which might itself be responsible for cardioembolic stroke. PMID: 32007362 [PubMed - as supplied by publisher]
Source: Archives of Cardiovascular Diseases - January 29, 2020 Category: Cardiology Authors: Py A, Schaaf M, Duhamel S, Si-Mohamed S, Daher J, Altman M, de Breyne B, Mechtouff L, Placide J, Chauveau S, Chevalier P, Nighoghossian N, Bergerot C, Thibault H Tags: Arch Cardiovasc Dis Source Type: research

A Stroke at 30,000 Feet? For One Lucky Passenger, It Wasn't
Title: A Stroke at 30,000 Feet? For One Lucky Passenger, It Wasn'tCategory: Health NewsCreated: 1/27/2020 12:00:00 AMLast Editorial Review: 1/28/2020 12:00:00 AM
Source: MedicineNet Heart General - January 28, 2020 Category: Cardiology Source Type: news

Ticagrelor Shows Benefit in Acute Stroke: THALES Topline Results Ticagrelor Shows Benefit in Acute Stroke: THALES Topline Results
Initial results from the phase 3 trial show a reduction in the primary endpoint of death or repeat stroke at 30 days with ticagrelor plus aspirin vs aspirin alone.Medscape Medical News
Source: Medscape Cardiology Headlines - January 27, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Quality benchmarks for chest pain units and stroke units in Germany.
CONCLUSION: As reimbursement for emergency medicine in Germany was recently rearranged, quality benchmarking has gained incremental importance. Mandatory joint quality measurement in both concepts ensuring gap analysis and process improvement is encouraged. PMID: 31970463 [PubMed - as supplied by publisher]
Source: Herz - January 25, 2020 Category: Cardiology Tags: Herz Source Type: research

Eicosapentaenoic-to-Arachidonic Acid Ratio Predicts Mortality and Recurrent Vascular Events in Ischemic Stroke Patients.
CONCLUSIONS: Low EPA/AA ratio at baseline and treatment without statins could predict mortality, recurrent ischemic stroke, cardiovascular and peripheral artery diseases, and hemorrhagic stroke among patients with acute ischemic stroke. The combination of baseline EPA/AA ratio and statin therapy could be critical in predicting the long-term prognosis of ischemic stroke patients. PMID: 31969533 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - January 25, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Baseline Characteristics of Elderly Japanese Patients Aged ≥75 Years With Non-Valvular Atrial Fibrillation and a History of Stroke - ANAFIE Registry.
CONCLUSIONS: In this unique nationwide NVAF registry of >30,000 elderly patients, >90% of patients, even those with HS, received anti-thrombotic therapy, nearly always with OAC. DOAC were the major choice of OAC. PMID: 31983727 [PubMed - as supplied by publisher]
Source: Circulation Journal - January 25, 2020 Category: Cardiology Authors: Kanemaru K, Yoshimoto T, Inoue H, Yamashita T, Akao M, Atarashi H, Ikeda T, Okumura K, Koretsune Y, Shimizu W, Tsutsui H, Hirayama A, Yasaka M, Yamaguchi T, Teramukai S, Kimura T, Kaburagi J, Takita A, Kusano K, Toyoda K, All Nippon Atrial Fibrillation in Tags: Circ J Source Type: research

Mildly Abnormal Lipid Levels, but Not High Lipid Variability, Are Associated with Increased Risk of Myocardial Infarction and Stroke in 'Statin-Naive' Young Population: A Nationwide Cohort Study.
Conclusions: Mildly abnormal baseline lipid levels were associated with an increased future risk of ASCVD events, particularly MI, whereas measures of lipid variability were not. Therefore, in young adults, achieving optimal lipid levels could be valuable in the prevention of ASCVD. PMID: 31978313 [PubMed - as supplied by publisher]
Source: Circulation Research - January 24, 2020 Category: Cardiology Authors: Park JB, Kim D, Lee H, Hwang IC, Yoon YE, Park HE, Choi SY, Kim YJ, Cho GY, Han KD, Kim HK Tags: Circ Res Source Type: research