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Specialty: Cancer & Oncology
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Total 1099 results found since Jan 2013.
Impact of Cardiovascular Disease on the Death Certificate Diagnosis of Heart Failure, Ischemic Heart Disease, and Cerebrovascular Disease - The Japan Public Health Center-Based Prospective Study
CONCLUSIONS: HF as the UCD was partly explained by CVD. The data imply that most HF deaths reported in vital statistics may be associated with underlying causes other than CVD.PMID:36948630 | DOI:10.1253/circj.CJ-22-0805
Source: Cancer Control - March 22, 2023 Category: Cancer & Oncology Authors: Isao Saito Kazumasa Yamagishi Yoshihiro Kokubo Hiroshi Yatsuya Hiroyasu Iso Norie Sawada Manami Inoue Shoichiro Tsugane Source Type: research
Outcomes of Early Rhythm Control Therapy in Patients With Atrial Fibrillation and a High Comorbidity Burden in Large Real-World Cohorts
CONCLUSIONS: ERC is safe and may be more favorable in a population-based sample of patients with high a comorbidity burden (CHA2DS2-VASc score ≥4).PMID:36942567 | DOI:10.1161/CIRCEP.122.011585
Source: Cancer Control - March 21, 2023 Category: Cancer & Oncology Authors: Jannis Dickow Shinwan Kany Victor Roth Cardoso Patrick T Ellinor Georgios V Gkoutos Holly K Van Houten Paulus Kirchhof Andreas Metzner Peter A Noseworthy Xiaoxi Yao Andreas Rillig Source Type: research
Healthcare systems data in the context of clinical trials - A comparison of cardiovascular data from a clinical trial dataset with routinely collected data
CONCLUSION: Concordance between datasets was lower than anticipated and the HSD used could not straightforwardly replace current trial practices, nor directly identify protocol-defined CVS events. Further work is required to improve the quality of HSD and consider event definitions when designing clinical trials incorporating HSD.PMID:36933612 | DOI:10.1016/j.cct.2023.107162
Source: Clinical Lung Cancer - March 18, 2023 Category: Cancer & Oncology Authors: Archie Macnair Matthew Nankivell Macey L Murray Stuart D Rosen Sally Appleyard Matthew R Sydes Sylvia Forcat Andrew Welland Noel W Clarke Stephen Mangar Howard Kynaston Roger Kockelbergh Abdulla Al-Hasso John Deighan John Marshall Mahesh Parmar Ruth E Lan Source Type: research
Clonal Hematopoiesis of Indeterminate Potential: Current Understanding and Future Directions
This article summarizes the current knowledge about clonal hematopoiesis of indeterminate potential (CHIP), its association with cardiovascular disease (CVD), and other outcomes, pathogenesis, postulated mechanisms of various pathologies, current knowledge gaps, possible targets of intervention, and therapeutic implications.Recent FindingsRecently, a common age-related hematological entity known as CHIP has been identified as the independent risk factor for CVD. CHIP is defined as the presence of clonally expanded blood cells involving leukemogenic mutations without the evidence of malignancy. CHIP is known to increase the...
Source: Current Oncology Reports - March 16, 2023 Category: Cancer & Oncology Source Type: research
Clonal Hematopoiesis and the Heart: a Toxic Relationship
AbstractPurpose of ReviewClonal
hematopoiesis (CH) refers to the expansion of hematopoietic stem cell clones and their cellular progeny due to somatic mutations, mosaic chromosomal alterations (mCAs), or copy number variants which naturally accumulate with age. CH has been linked to increased risk of blood cancers, but CH has also been linked to adverse cardiovascular outcomes.Recent FindingsA combination of clinical outcome studies and mouse models have offered strong evidence that CH mutations either correlate with or cause atherosclerosis, diabetes mellitus, chronic kidney disease, heart failure, pulmonary hypertensi...
Source: Current Oncology Reports - March 15, 2023 Category: Cancer & Oncology Source Type: research
Increased risk of stroke among patients with ankylosing spondylitis: A systematic review and meta-analysis
CONCLUSION: This study reveals that ankylosing spondylitis was associated with an increased risk of suffering a stroke. Management of cerebrovascular risk factors and the control of systemic inflammation should be considered in patients with ankylosing spondylitis.PMID:36906389 | DOI:10.1016/j.reumae.2023.02.002
Source: Cancer Control - March 11, 2023 Category: Cancer & Oncology Authors: Akshaya Srikanth Bhagavathula Barry L Bentley Benjamin Woolf Thusharika D Dissanayaka Jamal Rahmani Source Type: research
Cardiovascular outcomes among patients with castration-resistant prostate cancer: A comparative safety study using US administrative claims data
CONCLUSIONS: Our study sought to quantify risk of HHF, AMI and ischemic stroke among CRPC patients initiating AAP relative to ENZ within a national administrative claims database. Increased risk for HHF among AAP compared to ENZ users was observed. The difference in myocardial infarction did not attain statistical significance after controlling for residual bias, and no differences were noted in ischemic stroke between the two treatments. These findings confirm labeled warnings and precautions for AAP for HHF and contribute to the comparative real-world evidence on AAP relative to ENZ.PMID:36879362 | DOI:10.1002/pros.24510
Source: Cancer Control - March 6, 2023 Category: Cancer & Oncology Authors: Mitchell M Conover James Weaver Bo Fan Gerhard Leitz Ute Richarz Qing Li Dina Gifkins Source Type: research
Cardiovascular Risks in Testicular Cancer: Assessment, Prevention, and Treatment
AbstractPurpose of ReviewTesticular cancer (TC) is the leading cancer in men between 18 and 39 years of age. Current treatment involves tumor resection followed by surveillance and/or one or more lines of cisplatin-based chemotherapy (CBCT) and/or bone marrow transplant (BMT). Ten years after treatment, CBCT has been associated with significant atherosclerotic cardiovascular disease (CVD) i ncluding myocardial infarction (MI), stroke, and heightened rates of hypertension, dyslipidemia, diabetes mellitus, and metabolic syndrome (MetS). Additionally, low testosterone levels and hypogonadism contribute to MetS and may furth...
Source: Current Oncology Reports - March 3, 2023 Category: Cancer & Oncology Source Type: research
Dietary diversity and risk of late-life disabling dementia in middle-aged and older adults
CONCLUSIONS: Our findings indicate that eating a variety of foods may prevent disabling dementia only among women. Thus, the habit of consuming a variety of food items has important public health implications for women.PMID:36863290 | DOI:10.1016/j.clnu.2023.02.002
Source: Cancer Control - March 2, 2023 Category: Cancer & Oncology Authors: Rei Otsuka Shu Zhang Hikaru Ihira Norie Sawada Manami Inoue Kazumasa Yamagishi Nobufumi Yasuda Shoichiro Tsugane Source Type: research
Structural Insight on GPR119 Agonist as Potential Therapy for Type II Diabetes: A Comprehensive Review
Mini Rev Med Chem. 2023 Mar 2. doi: 10.2174/1389557523666230302140658. Online ahead of print.ABSTRACTDiabetes Mellitus [DM] is a long-term metabolic condition that is characterized by excessive blood glucose. DM is the third most death-causing disease, leading to retinopathy, nephropathy, loss of vision, stroke, and cardiac arrest. Around 90% of the total cases of diabetic patients have Type II Diabetes Mellitus[T2DM]. Among various approaches for the treatment of T2DM. G protein-coupled receptors [GPCRs] 119 have been identified as a new pharmacological target. GPR119 is distributed preferentially in the pancreas β-cells...
Source: Cancer Control - March 2, 2023 Category: Cancer & Oncology Authors: Priyanshu Nema Vivek Asati Priyadarshi Kendya Twinkle Gupta Shivangi Agarwal Shivam Kori Varsha Kashaw Arun K Iyer Sushil Kumar Kashaw Source Type: research
Retrospective, multicenter study of surgical treatment for carotid body tumors with or without preoperative embolization
ConclusionThere was insufficient evidence to support the efficacy of preoperative embolization. CBT resection alone had a similar rate of stoke, recurrence, and CN injuries when compared with CBT resection with preoperative arterial embolization. Meanwhile, CBT resection alone did not increase LOO and IBL.
Source: Frontiers in Oncology - March 2, 2023 Category: Cancer & Oncology Source Type: research
Using Artificial Intelligence to Develop a Multivariate Model with a Machine Learning Model to Predict Complications in Mexican Diabetic Patients without Arterial Hypertension (National Nested Case-Control Study): Metformin and Elevated Normal Blood Pressure Are Risk Factors, and Obesity Is Protective
In conclusion, the results we have obtained show that artificial intelligence is a powerful and feasible tool to use for this type of study. However, we suggest that more studies be conducted to verify and elaborate upon our findings.PMID:36846513 | PMC:PMC9949947 | DOI:10.1155/2023/8898958
Source: Cancer Control - February 27, 2023 Category: Cancer & Oncology Authors: Sergio A Zaizar-Fregoso Agustin Lara-Esqueda Carlos M Hern ández-Suarez Josuel Delgado-Enciso Arturo Garcia-Nevares Luis M Canseco-Avila Jose Guzman-Esquivel Iram P Rodriguez-Sanchez Margarita L Martinez-Fierro Gabriel Ceja-Espiritu Hector Ochoa-D íaz-L Source Type: research
Physical health risks of middle-aged people with low social independence: fatal diseases in men, and little attendance to cancer screenings in both sexes
CONCLUSIONS: In terms of current physical health, low-social-independent men have more fatal diseases. Both sexes with low social independence seldom attend cancer screenings and have an increased risk of developing progressive cancer in the future. At least in terms of non-smoking and non-drinking, they live healthier lives than the control group, and what makes low-social-independent men have various fatal diseases is still unclear.PMID:36846461 | PMC:PMC9948749 | DOI:10.7717/peerj.14904
Source: Cancer Control - February 27, 2023 Category: Cancer & Oncology Authors: Haruaki Naito Katsuya Nitta Misooja Lee Takeshi Ushigusa Motoki Osawa Takahiro Tabuchi Yasuhiro Kakiuchi Source Type: research
Nuts and Cardiovascular Disease Outcomes: A Review of the Evidence and Future Directions
Nutrients. 2023 Feb 11;15(4):911. doi: 10.3390/nu15040911.ABSTRACTNuts are nutrient-rich foods that contain many bioactive compounds that are beneficial for cardiovascular health. Higher consumption of nuts has been associated with a reduced risk of several cardiovascular diseases (CVD) in prospective cohort studies, including a 19% and 25% lower risk of CVD incidence and mortality, respectively, and a 24% and 27% lower risk of coronary heart disease incidence and mortality, respectively. An 18% lower risk of stroke mortality, a 15% lower risk of atrial fibrillation, and a 19% lower risk of total mortality have also been o...
Source: Cancer Control - February 25, 2023 Category: Cancer & Oncology Authors: Andrea J Glenn Dagfinn Aune Heinz Freisling Noushin Mohammadifard Cyril W C Kendall Jordi Salas-Salvad ó David J A Jenkins Frank B Hu John L Sievenpiper Source Type: research
