Query: stroke

Filtered By:
Specialty: Urology & Nephrology

This page shows you your search results in order of date.

Order by Relevance | Date

Total 463 results found since Jan 2013.

SGLT2 inhibitor therapy in patients with type-2 diabetes mellitus: is acute kidney injury a concern?
Abstract Sodium-glucose co-transporter-2 (SGLT2) inhibitor drugs are effective for treatment of type-2 diabetes mellitus. These medications target the SGLT2 transporter in the proximal convoluted tubule to prevent reabsorption of filtered glucose, resulting in glucosuria. Other clinically meaningful benefits beyond glycemic control include reductions in blood pressure, weight, and albuminuria. Three large clinical trials and subsequent meta-analyses studying SGLT2 inhibitors demonstrated significant cardiovascular benefits including reductions in heart failure hospitalizations, as well as reduced risk of myocardia...
Source: Journal of Nephrology - February 18, 2020 Category: Urology & Nephrology Authors: Baker ML, Perazella MA Tags: J Nephrol Source Type: research

PPARγ is a gatekeeper for extracellular matrix and vascular cell homeostasis: beneficial role in pulmonary hypertension and renal/cardiac/pulmonary fibrosis
Purpose of review Pulmonary arterial hypertension (PAH) is characterized by pulmonary arterial endothelial cell (PAEC) dysfunction and apoptosis, pulmonary arterial smooth muscle cell (PASMC) proliferation, inflammation, vasoconstriction, and metabolic disturbances that include disrupted bone morphogenetic protein receptor (BMPR2)-peroxisome proliferator-activated receptor gamma (PPARγ) axis and DNA damage. Activation of PPARγ improves many of these mechanisms, although erroneous reports on potential adverse effects of thiazolidinedione (TZD)-class PPARγ agonists reduced their clinical use in the past decade. Here, we...
Source: Current Opinion in Nephrology and Hypertension - January 30, 2020 Category: Urology & Nephrology Tags: PATHOPHYSIOLOGY OF HYPERTENSION: Edited by Nancy J. Brown Source Type: research

Kidney dysfunction is associated with risk of cardiovascular events in middle-aged and elderly population with hypertension: A  5-year community-based cohort study in China
.
CONCLUSION: Moderate to severe kidney dysfunction was an independent risk predictor of CVD events. Among subjects with hypertension or poorly controlled blood pressure level, the presence of CKD significantly increased the risks of CVD events and stroke.
. PMID: 31983380 [PubMed - as supplied by publisher]
Source: Clinical Nephrology - January 27, 2020 Category: Urology & Nephrology Authors: Gu X, Fang X, Ji X, Tang Z, Wang C, Guan S, Wu X, Liu H, Zhang Z Tags: Clin Nephrol Source Type: research

Readmissions after Acute Kidney Injury during Left Ventricular Assist Device Implantation Hospitalization.
CONCLUSION: AKI-D was associated with highest -30-day readmission risk, possibly related to negatively synergistic effects of LVAD, kidney dysfunction, and dialysis related factors on infection and GI bleeding risks. AKI alone was not associated with increased readmission risk. PMID: 31962311 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - January 21, 2020 Category: Urology & Nephrology Authors: Walther CP, Winkelmayer WC, Deswal A, Niu J, Navaneethan SD Tags: Am J Nephrol Source Type: research

Selected cardiovascular risk factors in early stages of chronic kidney disease
AbstractCardiovascular diseases, including hypertension, congestive heart failure, myocardial infarction, stroke and atherosclerosis, are common in patients with chronic kidney disease. Aside from the standard biomarkers, measured to determine cardiovascular risk, new ones have emerged: markers of oxidative stress, apoptosis, inflammation, vascular endothelium dysfunction, atherosclerosis, organ calcification and fibrosis. Unfortunately, their utility for routine clinical application remains to be elucidated. A causal relationship between new markers and cardiovascular diseases in patients with chronic kidney disease remai...
Source: International Urology and Nephrology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Coronary artery bypass grafting vs. drug-eluting stent implantation in patients with end-stage renal disease requiring dialysis.
Conclusions: Among patients with CAD and dialysis-dependent chronic kidney disease (CKD), treatment with CABG or PCI with DES exhibited similar long-term outcomes. However, CABG was associated with higher short-term risk of death. Higher mortality was revealed in patients over 65 years and underwent PD. PMID: 31918608 [PubMed - in process]
Source: Renal Failure - January 12, 2020 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Acute kidney injury with neurological features: Beware of the star fruit and its caramboxin
We present a case of a 51-year-old male with paresis and altered mental status. Screening for neurological diseases such as stroke, Guillain-Barre, meningitis and encephalitis were negative. In the evolution, he developed acute kidney failure and was submitted to 4 dialysis sessions. After talking to the family, we discovered he had ingested over 50 star fruits prior to the acute neurologic deficits. He recovered renal function so a renal biopsy was not required. Physicians should actively look for star fruit ingestion history in patients presenting with unexplained acute kidney injury with or without neurological features...
Source: Indian Journal of Nephrology - January 8, 2020 Category: Urology & Nephrology Authors: Matheo A . M. Stumpf Adriana F. M. Schuinski Gilberto Baroni Maikel Ramthun Source Type: research

Clinical outcomes after percutaneous coronary intervention in non-dialysis patients with acute coronary syndrome and advanced renal dysfunction
ConclusionsShort- and long-term prognoses following PCI in non-dialysis patients with ACS and advanced renal dysfunction is still unfavorable. STEMI and Killip classification  ≥ 2 were independent predictors for in-hospital MACCE, and body mass index and serum albumin were for post-discharge MACCE.
Source: Clinical and Experimental Nephrology - January 6, 2020 Category: Urology & Nephrology Source Type: research

Effect of renin –angiotensin system blockade on graft survival and cardiovascular disease in kidney transplant recipients: retrospective multicenter study in Japan
ConclusionThus, RASBs potentially reduce stroke events in KT recipients.
Source: Clinical and Experimental Nephrology - December 26, 2019 Category: Urology & Nephrology Source Type: research

The association between CHA2DS2-VASc score and erectile dysfunction: a cross-sectional study
Conclusion: CHA2DS2-VASc score can be used to detect Erectile dysfunction in patients who are admitted to the cardiology outpatient clinics.
Source: International Braz J Urol - December 20, 2019 Category: Urology & Nephrology Source Type: research

Myeloperoxidase and the Risk of CKD Progression, Cardiovascular Disease, and Death in the Chronic Renal Insufficiency Cohort (CRIC) Study
ConclusionsHigher MPO level was associated with increased risk for CKD progression, but not with CVD and death in patients with CKD from CRIC. Whether therapies aimed at reducing MPO activity can result in improved clinical outcomes is yet to be determined.
Source: American Journal of Kidney Diseases - December 20, 2019 Category: Urology & Nephrology Source Type: research

Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats.
CONCLUSION: Berberine treatment improved short-term memory in hyperlipidemia by increasing neuronal proliferation and inhibiting neuronal apoptosis. Berberine treatment also improved lipid metabolism. PMID: 31795609 [PubMed]
Source: International Neurourology Journal - December 6, 2019 Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research

Impact of Cardio-Renal-Metabolic Comorbidities on Cardiovascular Outcomes and Mortality in Type 2 Diabetes Mellitus.
CONCLUSION: In T2DM patients, CKD presence was associated with higher risk of modified MACE, HF, and ACM. This may have risk-stratification implications for T2DM patients based on background CKD and highlights the potential importance of novel renoprotective strategies. PMID: 31812955 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - December 6, 2019 Category: Urology & Nephrology Authors: Cherney DZI, Repetto E, Wheeler DC, Arnold SV, MacLachlan S, Hunt PR, Chen H, Vora J, Kosiborod M Tags: Am J Nephrol Source Type: research

Potassium binding for conservative and preservative management of chronic kidney disease
In conclusion, there are new well tolerated and effective K+-binding agents for acutely and chronically managing hyperkalemia.
Source: Current Opinion in Nephrology and Hypertension - November 29, 2019 Category: Urology & Nephrology Tags: NOVEL THERAPEUTIC APPROACHES IN NEPHROLOGY AND HYPERTENSION: Edited by Kamyar Kalantar-Zadeh and Ekamol Tantisattamo Source Type: research

Impact of prior stroke on major clinical outcome in chronic kidney disease: the Salford kidney cohort study
Chronic kidney disease (CKD) is an independent risk factor for stroke in the general population. The impact of prior stroke on major clinical outcomes in CKD populations is poorly characterised.
Source: BMC Nephrology - November 27, 2019 Category: Urology & Nephrology Authors: James Tollitt, Aghogho Odudu, Emma Flanagan, Rajkumar Chinnadurai, Craig Smith and Philip A. Kalra Tags: Research article Source Type: research

The impact of acute kidney injury on fatality of ischemic stroke from a hospital-based population in Joinville, Brazil.
CONCLUSION: The presence of AKI is an important complication after ischemic stroke. Despite its impact on 30-day fatality, the predictive strength of AKI was limited by the severity of stroke. PMID: 31661544 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - October 30, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Prevention and treatment of stroke in patients with chronic kidney disease: an overview of evidence and current guidelines
Chronic Kidney Disease (CKD) is strongly associated with an increased risk of stroke, small vessel disease, and vascular dementia. Common vascular factors for stroke, such as hypertension, diabetes, and atrial fibrillation, are more prevalent in CKD patients, accounting for this association. However, factors unique to these patients, such as uraemia, oxidative stress, mineral and bone abnormalities, as well as dialysis-related factors are also believed to contribute to risk. Despite improvements in stroke treatment and survival in the general population, the rate of improvement in patients with CKD, especially those who ar...
Source: Kidney International - October 18, 2019 Category: Urology & Nephrology Authors: Dearbhla M. Kelly, Peter M. Rothwell Tags: Review Source Type: research

Serum lipoprotein(a) and risk of hemorrhagic stroke among incident peritoneal dialysis patients: a large study from a single center in China.
Conclusions: Among patients with incident PD, a higher serum Lp(a) level may predict a lower risk of hemorrhagic stroke. PMID: 31498021 [PubMed - in process]
Source: Renal Failure - September 10, 2019 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Lipid lowering and risk of haemorrhagic stroke in CKD
Nature Reviews Nephrology, Published online: 29 August 2019; doi:10.1038/s41581-019-0201-0Haemorrhagic stroke is more common in adults with chronic kidney disease (CKD) than in the general population. A recent study reports that low concentrations of LDL significantly increase the risk of haemorrhagic stroke. This finding challenges the concept of aggressive lipid lowering in patients with high cardiovascular risk, including those with CKD.
Source: Nature Reviews Nephrology - August 29, 2019 Category: Urology & Nephrology Authors: Steven Van Laecke Source Type: research

Mechanisms of Stroke in Patients with Chronic Kidney Disease.
Abstract BACKGROUND: Given the increasing worldwide prevalence of chronic kidney disease (CKD), it is critical to decrease the associated risk of debilitating vascular complications, including stroke, congestive heart failure, myocardial infarction, and peripheral vascular disease. Treatment options for reducing the risk of all subtypes of stroke in patients with CKD remain limited. For patients with end-stage kidney disease (ESKD), novel applications of noninvasive imaging may help personalize the type of dialysis and dialysis prescription for patients at high-risk. SUMMARY: This manuscript reviews the heigh...
Source: American Journal of Nephrology - August 28, 2019 Category: Urology & Nephrology Authors: Ghoshal S, Freedman BI Tags: Am J Nephrol Source Type: research

Comparison of risk of stroke in patients treated with peritoneal dialysis and hemodialysis: a systematic review and meta-analysis.
Conclusions: We observed that PD patients were less likely to develop hemorrhagic stroke than HD patients, and the risk for ischemic stroke was significantly higher for PD patients than for HD patients among the non-Asian patients. However, our findings could be biased due to the heterogeneity of the included studies. PMID: 31296101 [PubMed - in process]
Source: Renal Failure - July 14, 2019 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Clinical outcomes of stroke in hemodialysis patients: a retrospective single-center study
ConclusionsStroke outcome in these patients is dismal with prolonged hospital stay, poor functional status at discharge, very limited response to rehabilitation, and increased mortality.
Source: International Urology and Nephrology - July 1, 2019 Category: Urology & Nephrology Source Type: research

Under-recognized post-stroke acute kidney injury: risk factors and relevance for stroke outcome of a frequent comorbidity
ConclusionsPost-stroke AKI diagnosis needs to be improved by strictly monitoring individuals with cardioembolic or hemorrhagic stroke, reduced kidney function, higher Charlson Comorbidity Index and worse NIHSS at presentation.
Source: International Urology and Nephrology - June 20, 2019 Category: Urology & Nephrology Source Type: research

Relationship between History of Ischemic Stroke and All-Cause Mortality in Incident Dialysis Patients
Conclusion: The present study revealed that history of ischemic stroke before dialysis initiation was associated with all-cause, non-CV-related, and infection-related mortality and stroke event after dialysis initiation during maintenance dialysis.Nephron
Source: Nephron - June 11, 2019 Category: Urology & Nephrology Source Type: research

Stroke and renal artery stenosis from Takayasu's arteritis diagnosed in a 57-year-old male patient.
We report a case of a 57-year-old male patient with late diagnosis of TA and various related complications including stroke in the left middle cerebral artery territory, predominant left renal artery stenosis, and hypertension with discrepancy of blood pressure between two arms due to predominant left subclavian artery stenosis. Thus, physicians should keep in their mind this late presentation after the age of 40 years. The aim is to increase the awareness of this condition because of early diagnosis and the timely introduction of treatment can lead to improved outcomes in this poorly understood clinical enigma. PMID:...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Ur Rahman SS, Al Shehri A, Al Ghamdi M, Al Shareef M Tags: Saudi J Kidney Dis Transpl Source Type: research

Stroke and thromboembolic events in men with prostate cancer treated with definitive radiation therapy with or without androgen deprivation therapy
Stroke and thromboembolic events in men with prostate cancer treated with definitive radiation therapy with or without androgen deprivation therapy, Published online: 15 April 2019; doi:10.1038/s41391-019-0150-5Stroke and thromboembolic events in men with prostate cancer treated with definitive radiation therapy with or without androgen deprivation therapy
Source: Prostate Cancer and Prostatic Diseases - April 15, 2019 Category: Urology & Nephrology Authors: Rishi Deka Daniel R. Simpson Matthew S. Panizzon Richard L. Hauger Paul Riviere Vinit Nalawade Rana McKay James D. Murphy Brent S. Rose Source Type: research

Neuroanatomical correlates between stroke lesions and urinary disorders: A narrative review.
CONCLUSION: A few cerebral areas damaged by stroke seem to be linked to certain urinary troubles, but new studies with a higher methodological quality are required to confirm this result. PMID: 30527571 [PubMed - as supplied by publisher]
Source: Progres en Urologie - December 13, 2018 Category: Urology & Nephrology Tags: Prog Urol Source Type: research

Icodextrin is Associated with a Lower Risk of Stroke in Peritoneal Dialysis Patients
Conclusion: The use of icodextrin is associated with a lower incidence and risk of stroke in PD patients.Nephron
Source: Nephron - November 13, 2018 Category: Urology & Nephrology Source Type: research

Therapeutic Potential of Human Turbinate-Derived Mesenchymal Stem Cells in Experimental Acute Ischemic Stroke.
CONCLUSION: hTMSCs could improve functional recovery following ischemic stroke, of which efficacy was similar to AdMSCs. Although hTMSCs showed comparable infarct size and survival of grafted MSCs, transplantation of hTMSCs could upregulate subgranular neurogenesis with no impact on ectopically migrating newborn neurons. PMID: 30396262 [PubMed]
Source: International Neurourology Journal - November 8, 2018 Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research

Low serum phosphate is associated with ischemic stroke in hemodialysis patients
ConclusionsLow serum phosphate is a risk factor for developing ischemic stroke in hemodialysis patients. The results suggest that managing serum phosphate  ≥ 4.5 mg/dL among hemodialysis patients may reduce the risk of ischemic stroke.
Source: Clinical and Experimental Nephrology - October 1, 2018 Category: Urology & Nephrology Source Type: research

A case of recurrent embolic stroke of undetermined source in a chronic kidney disease patient undergoing hemodialysis.
Abstract PMID: 30381530 [PubMed - in process]
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Shindo M, Kaneko S, Minato S, Mutsuyoshi Y, Yanai K, Ishii H, Kitano T, Miyazawa H, Ito K, Ueda Y, Hirai K, Hoshino T, Ookawara S, Morishita Y Tags: Saudi J Kidney Dis Transpl Source Type: research

Managing of Lower Urinary Tract Dysfunction Following Stroke
AbstractPurpose of ReviewThis comprehensive up-to-date review will synthesise relevant available literature on the topic of post-stroke lower urinary tract dysfunction (LUTD). Topics include epidemiology of LUTD, LUTD as a prognostic indicator for stroke recovery, urinary incontinence and retention, correlations between brain lesion localisation and LUTD, causes of LUTD, medical complications due to LUTD, diagnostics and contemporary management of LUTD in stroke patients.Recent FindingsLUTD frequently occurs after a stroke and is associated with poor overall functional outcome, increased institutionalisation and mortality ...
Source: Current Bladder Dysfunction Reports - September 1, 2018 Category: Urology & Nephrology Source Type: research

Incident Atrial Fibrillation and the Risk of Stroke in Adults with Chronic Kidney Disease: The Stockholm CREAtinine Measurements (SCREAM) Project.
CONCLUSIONS: Patients with CKD who develop atrial fibrillation are at higher risk of stroke and death. PMID: 30030271 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - July 20, 2018 Category: Urology & Nephrology Authors: Carrero JJ, Trevisan M, Sood MM, Bárány P, Xu H, Evans M, Friberg L, Szummer K Tags: Clin J Am Soc Nephrol Source Type: research

Managing of Lower Urinary Tract Dysfunction Following Stroke
AbstractPurpose of ReviewThis comprehensive up-to-date review will synthesise relevant available literature on the topic of post-stroke lower urinary tract dysfunction (LUTD). Topics include epidemiology of LUTD, LUTD as a prognostic indicator for stroke recovery, urinary incontinence and retention, correlations between brain lesion localisation and LUTD, causes of LUTD, medical complications due to LUTD, diagnostics and contemporary management of LUTD in stroke patients.Recent FindingsLUTD frequently occurs after a stroke and is associated with poor overall functional outcome, increased institutionalisation and mortality ...
Source: Current Bladder Dysfunction Reports - June 11, 2018 Category: Urology & Nephrology Source Type: research

Low serum phosphate is associated with ischemic stroke in hemodialysis patients
ConclusionsLow serum phosphate is a risk factor for developing ischemic stroke in hemodialysis patients. The results suggest that managing serum phosphate  ≥ 4.5 mg/dL among hemodialysis patients may reduce the risk of ischemic stroke.
Source: Clinical and Experimental Nephrology - April 20, 2018 Category: Urology & Nephrology Source Type: research

Platelet indices and stroke.
Authors: Yildirim T, Akin F, Altun I, Yildirim SE, Basaran O, Soylu MO PMID: 29619869 [PubMed - in process]
Source: Renal Failure - April 7, 2018 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Neonatal stroke and haematuria: Questions
AbstractThis is a report of an infant born near term with neonatal stroke and haematuria. Changes were noted on foetal magnetic resonance images, and these persisted postnatally. A routine renal ultrasound scan during follow-up detected haematuria with no associated proteinuria. A likely pathogenic genetic mutation was identified. This case highlights a relatively newly discovered cause for hereditary nephropathy affecting the basement membrane, initially affecting the glomerular but later the renal tubular basement membranes. The renal phenotype, pathogenic genotype and pathological findings on renal biopsy are discussed.
Source: Pediatric Nephrology - March 21, 2018 Category: Urology & Nephrology Source Type: research

Neonatal stroke and haematuria: Answers
ConclusionsThis case highlights a relatively newly discovered cause of hereditary nephropathy in which the basement membrane is affected, with initial effects on the glomerular membranes and subsequent effects on the renal tubular basement membranes.
Source: Pediatric Nephrology - March 21, 2018 Category: Urology & Nephrology Source Type: research

High Right Ventricular Stroke Work Index Is Associated with Worse Kidney Function in Patients with Heart Failure with Preserved Ejection Fraction
Conclusion: High right ventricular workload indicated by high RVSWI is associated with worse renal function in patients with Cpc-PH. Further prospective studies are needed to better understand this association.Cardiorenal Med 2018;8:123 –129
Source: Cardiorenal Medicine - February 28, 2018 Category: Urology & Nephrology Source Type: research

Association of dialysis with in ‐hospital disability progression and mortality in community‐onset stroke
CONCLUSIONSDialysis was associated with an increased risk of in‐hospital disability progression and mortality among patients with community‐onset stroke, regardless of stroke subtype.
Source: Nephrology - February 22, 2018 Category: Urology & Nephrology Authors: Tomoko Usui, Norio Hanafusa, Hideo Yasunaga, Masaomi Nangaku Tags: Original Article Source Type: research

Stroke volume variation and serum creatinine changes during abdominal aortic aneurysm surgery: a time-integrated analysis.
CONCLUSIONS: SVV increases progressively during and after AAA surgery in subjects who will develop AKI. The increase of SVV precedes and predicts the rise in sCr and is a good discriminator of the development of AKI. AKI is associated with an increased long-term risk for MACCE. PMID: 29344813 [PubMed - as supplied by publisher]
Source: Journal of Nephrology - January 17, 2018 Category: Urology & Nephrology Authors: Lentini P, Zanoli L, Fatuzzo P, Husain-Syed F, Stramanà R, Cognolato D, Catena V, Baiocchi M, Granata A, Dell'Aquila R Tags: J Nephrol Source Type: research

Warfarin Use And the Risk Of Stroke, Bleeding, And Mortality In Older Adults On Dialysis With Incident Atrial Fibrillation
ConclusionOlder ESRD patients with AF who were treated with warfarin had a no difference in stroke risk, lower mortality risk, but increased major bleeding risk. The bleeding risk associated with warfarin was greater among women than men. The risk/benefit ratio of warfarin may be less favorable among older women.
Source: Nephrology - December 1, 2017 Category: Urology & Nephrology Authors: Jingwen Tan, Sunjae Bae, Jodi B. Segal, Junya Zhu, G. Caleb Alexander, Dorry L. Segev, Mara McAdams ‐DeMarco Tags: Original Article Source Type: research

Oral Anticoagulants to Prevent Stroke in Nonvalvular Atrial Fibrillation in Patients With CKD Stage 5D: An NKF-KDOQI Controversies Report
Publication date: Available online 21 September 2017 Source:American Journal of Kidney Diseases Author(s): Vinod K. Bansal, Charles A. Herzog, Mark J. Sarnak, Michael J. Choi, Ravindra Mehta, Bernard G. Jaar, Michael V. Rocco, Holly Kramer Stroke risk may be more than 3-fold higher among patients with chronic kidney disease stage 5D (CKD-5D) compared to the general population, with the highest stroke rates noted among those 85 years and older. Atrial fibrillation (AF), a strong risk factor for stroke, is the most common arrhythmia and affects >7% of the population with CKD-5D. Warfarin use is widely acknowledged as...
Source: American Journal of Kidney Diseases - September 21, 2017 Category: Urology & Nephrology Source Type: research

Decreased percentage of peripheral na ïve T cells is independently associated with ischemic stroke in patients on hemodialysis
ConclusionA decrease in percentage of peripheral CD4 na ïve T cells is a risk factor for ischemic stroke in patients on hemodialysis.
Source: International Urology and Nephrology - September 15, 2017 Category: Urology & Nephrology Source Type: research

Reverse epidemiology of elevated blood pressure among chronic hemodialysis black patients with stroke: a historical cohort study
The objective of this study was to assess the extent of stroke in chronic hemodialysis patients.
Source: BMC Nephrology - August 30, 2017 Category: Urology & Nephrology Authors: Yannick Nlandu, Fran çois Lepira, Jean-Robert Makulo, Yannick Engole, Ernest Sumaili, Marie-Noelle Wameso, Vieux Mokoli, Jeannine Luse, Augustin Longo, Chantal Zinga, Pierre Akilimali, Aliocha Nkodila, Mélanie Bavassa, François Kajingulu, Justine Bukab Tags: Research article Source Type: research

Predicting in a predicament: Stroke and hemorrhage risk prediction in dialysis patients with atrial fibrillation.
Abstract Whether to anticoagulate dialysis patients with atrial fibrillation is a common clinical dilemma with limited high-quality data to inform decision-making. While the efficacy and safety of anticoagulation for stroke prevention in dialysis patients with atrial fibrillation has long been debated and remains unclear, the more upstream issue of stroke risk assessment from atrial fibrillation has received relatively little attention. In the general population, a handful of risk scores to help predict stroke and hemorrhage risk in the setting of atrial fibrillation are widely validated and applied in clinical pr...
Source: Seminars in Dialysis - July 11, 2017 Category: Urology & Nephrology Authors: Molnar AO, Sood MM Tags: Semin Dial Source Type: research

ESRD After Heart Failure, Myocardial Infarction, or Stroke in Type  2 Diabetic Patients With CKD
Conclusions Most ESRD cases occurred in individuals without intercurrent CV events who had lower eGFRs than individuals with intercurrent CV events, but similar post-ESRD mortality. Nevertheless, intercurrent CV events, particularly heart failure, are strongly associated with risk for ESRD. These findings underscore the need for kidney-specific therapies in addition to treatment of CV risk factors to lower ESRD incidence in diabetes.
Source: American Journal of Kidney Diseases - June 7, 2017 Category: Urology & Nephrology Source Type: research

Stroke in patients with chronic kidney disease & #8230;: How do we approach and manage it ?
This article is a review of stroke in patients with CKD and approach to managing it.
Source: Indian Journal of Nephrology - May 3, 2017 Category: Urology & Nephrology Authors: S Nayak-Rao MP Shenoy Source Type: research

Recent Advances in Stroke Prevention in Patients with Atrial Fibrillation and End-Stage Renal Disease
Background: Chronic kidney disease (CKD) is associated with a high prevalence of atrial fibrillation (AF), but in this population the risk/benefit ratio of anticoagulant therapy with vitamin K antagonists (VKA) for thromboprophylaxis is uncertain.Summary: In end-stage renal disease (ESRD) patients undergoing hemodialysis, VKA seem less effective in stroke prevention than in the general population, with an increased risk of major bleeding. Recently, novel oral anticoagulant agents (NOACs) have proven to be effective for stroke prevention in AF and have demonstrated an improved safety profile compared to VKA. Limited data fr...
Source: Cardiorenal Medicine - April 26, 2017 Category: Urology & Nephrology Source Type: research

Effects of stroke on changes in heart rate variability during hemodialysis
Stroke and low heart rate variability (HRV) are both associated with an unfavorable prognosis in hemodialysis patients. The relationship between stroke and changes in HRV during hemodialysis remains unclear.
Source: BMC Nephrology - March 16, 2017 Category: Urology & Nephrology Authors: Jiun-Chi Huang, Chien-Fu Chen, Chia-Chu Chang, Szu-Chia Chen, Ming-Chia Hsieh, Yao-Peng Hsieh and Hung-Chun Chen Source Type: research