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Total 314 results found since Jan 2013.

Commentary on "Validation of the Pediatric Stroke Outcome Measure for classifying overall neurological deficit".
PMID: 32359224 [PubMed - as supplied by publisher]
Source: Pediatric Research - May 1, 2020 Category: Pediatrics Authors: Chung MG, Lo W Tags: Pediatr Res Source Type: research

Validation of the pediatric stroke outcome measure for classifying overall neurological deficit.
CONCLUSION: The PSOM-SCS constitutes a valid tool for classifying overall neurological severity emphasizing function and encompassing the full range of severity in pediatric stroke. IMPACT: Arithmetic summing of the PSOM subscales scores to assess severity classification is inadequate.The prior severity classification using PSOM overestimates poor outcomes.Three distinct severity profiles using PSOM subscales are identified.The PSOM-SCS is in moderate to excellent agreement with other disability measures.PSOM-SCS offers a valid tool for classifying the overall neurological deficit severity. PMID: 32179868 [PubMed...
Source: Pediatric Research - March 15, 2020 Category: Pediatrics Authors: Slim M, Fox CK, Friefeld S, Dlamini N, Westmacott R, Moharir M, MacGregor D, deVeber G, SIPS Investigators Tags: Pediatr Res Source Type: research

Pediatric Acute Stroke Protocol Implementation and Utilization Over 7  Years
To examine the implementation and utilization of a pediatric acute stroke protocol over a 7-year period, hypothesizing improvements in protocol implementation and increased protocol use over time.
Source: The Journal of Pediatrics - March 4, 2020 Category: Pediatrics Authors: Jessica D. Wharton, Megan M. Barry, Chelsea A. Lee, Kayla Massey, Travis R. Ladner, Lori C. Jordan Tags: Original Articles Source Type: research

Precise neonatal arterial ischemic stroke classification with a three-dimensional map of the arterial territories of the neonatal brain.
CONCLUSION: The ATNB map has been proven useful to precisely identify the arterial territories affected by an NAIS, as well as to increase the accuracy of clinical diagnoses. PMID: 31835270 [PubMed - as supplied by publisher]
Source: Pediatric Research - December 12, 2019 Category: Pediatrics Authors: Núñez C, Arca G, Agut T, Stephan-Otto C, García-Alix A Tags: Pediatr Res Source Type: research

A Stroke Alert Protocol Decreases the Time to Diagnosis of Brain Attack Symptoms in a Pediatric Emergency Department
To determine whether a stroke alert system decreases the time to diagnosis of children presenting to the emergency department (ED) with acute-onset focal neurologic deficits.
Source: The Journal of Pediatrics - November 4, 2019 Category: Pediatrics Authors: Dana B. Harrar, Catherine L. Salussolia, Kush Kapur, Amy Danehy, Monica E. Kleinman, Rebekah Mannix, Michael J. Rivkin Tags: Original Articles Source Type: research

Mechanical Thrombectomy Using Retrievable Stents in Pediatric Acute Ischemic Stroke.
CONCLUSION: Mechanical thrombectomy using retrievable stents is a safe and effective therapy for pediatric ischemic stroke due to large vessel occlusion, and may be offered in carefully selected patients. PMID: 31333212 [PubMed - in process]
Source: Indian Pediatrics - July 14, 2019 Category: Pediatrics Authors: Bhatti A, Huded V, Vyas D, Mushtaq M, Kekatpure M, Hiremath S, Sapare A, Aggarwal R Tags: Indian Pediatr Source Type: research

Nonpharmacological rehabilitation interventions for motor and cognitive outcomes following pediatric stroke: a systematic review
Conclusion: Effective rehabilitation approaches are important for optimizing outcomes in children who have had a stroke. Although the number of published clinical trials has increased in recent years, little evidence-based guidance exists for this clinical population.What is Known:• Pediatric stroke is a significant cause of disability in children that is often associated with long-term motor and cognitive sequelae.• There is a need to establish a knowledge base regarding available evidence-based rehabilitation therapies for this clinical population.What is New:• Most studies examining interventions for motor functio...
Source: European Journal of Pediatrics - February 27, 2019 Category: Pediatrics Source Type: research

Diffuse optical tomography for the detection of perinatal stroke at the cot side: a pilot study.
CONCLUSION: This suggests that DOT and correlation-based analyses in the low-frequency range can potentially aid the early detection of perinatal stroke, prior to MRI acquisition. Additional methodological advances are required to increase the sensitivity and specificity of this technique. PMID: 30759451 [PubMed - as supplied by publisher]
Source: Pediatric Research - February 13, 2019 Category: Pediatrics Authors: Chalia M, Dempsey LA, Cooper RJ, Lee CW, Gibson AP, Hebden JC, Austin T Tags: Pediatr Res Source Type: research

The effect of unilateral stroke on autonomic function in the term newborn.
CONCLUSION: Based on these findings, it is difficult to reconcile the functional topography of the central autonomic system in term newborns with that currently proposed for the normal mature brain. Further investigation is clearly needed. PMID: 30712058 [PubMed - as supplied by publisher]
Source: Pediatric Research - February 2, 2019 Category: Pediatrics Authors: Reich DA, Govindan RB, Whitehead MT, Wang J, Chang T, Kota S, du Plessis AJ Tags: Pediatr Res Source Type: research

Health Tip: Risk Factors for Stroke in Kids
Title: Health Tip: Risk Factors for Stroke in KidsCategory: Health NewsCreated: 1/1/2019 12:00:00 AMLast Editorial Review: 1/2/2019 12:00:00 AM
Source: MedicineNet Kids Health General - January 2, 2019 Category: Pediatrics Source Type: news

Short ‐term neurological outcomes in ischemic and hemorrhagic pediatric stroke
ConclusionsPediatric stroke is associated with poor prognosis in a substantial number of patients in short term, with CSVT having the worst prognosis. Not only ischemic but also hemorrhagic stroke were presented with detailed patient characteristics, with a full thrombosis panel achieved for most ischemic stroke patients.This article is protected by copyright. All rights reserved.
Source: Pediatrics International - November 18, 2018 Category: Pediatrics Authors: Tu ğçe Aksu Uzunhan, Nur Aydinli, Mine Çalişkan, Burak Tatli, Meral Özmen Tags: Original Articles Source Type: research

Symptom patterns in childhood arterial ischemic stroke: Analysis of a population-based study in Germany
Conclusions Any new focal neurological deficit in isolation, or associated with seizures or further non-specific symptoms should alert to childhood stroke. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Klinische Padiatrie - October 10, 2018 Category: Pediatrics Authors: Gerstl, Lucia Weinberger, Raphael von Kries, R üdiger Heinen, Florian Sebastian Schroeder, Andreas Veronika Bonfert, Michaela Borggr äfe, Ingo Tacke, Moritz Vill, Katharina N. Landgraf, Mirjam Kurnik, Karin Olivieri, Martin Tags: Original Article Source Type: research

Childhood arterial ischemic stroke in Senegal (West Africa).
Abstract Etiological factors of childhood ischemic stroke depend on the epidemiological context. The purpose of this study was to determine the risk factors, the clinical and radiologic features, and the outcome of arterial ischemic stroke in a case series of Senegalese children. We carried out a retrospective registry-based study on arterial ischemic stroke in children hospitalized in the neurology department of Fann Teaching Hospital and Albert Royer Children's Hospital, from January 2005 to December 2015. We enrolled 116 cases with an age range from 2 months to 18 years. The mean age at stroke occurrence was 71...
Source: Archives de Pediatrie - August 21, 2018 Category: Pediatrics Authors: Ndiaye M, Lengue F, Sagna SD, Sow AD, Fogany Y, Deme H, Basse AM, Diop-Sene MS, Diagne NS, Diop AG, Ndiaye O, Ndiaye MM Tags: Arch Pediatr Source Type: research

Perinatal arterial ischaemic stroke in  term babies
Perinatal arterial ischaemic stroke (PAIS) affects between 1:2300 and 1:4000 births, so most paediatricians and neonatologists will see a number of cases during their working life. The exact cause of PAIS in an individual usually is unknown, and discussion may occur about whether prothrombotic investigations, aspirin or anticoagulation are needed. The causes, investigation and treatment of PAIS are completely different from stroke in the older paediatric and adult group. Outcome tends to be good, although cerebral palsy may be seen in up to 30% of cases, epilepsy in 15 –25% and cognitive problems may also occur.
Source: Paediatrics and Child Health - August 16, 2018 Category: Pediatrics Authors: Anthony R Hart, Daniel JA Connolly, Rahul Singh Tags: Symposium: neonatology Source Type: research

Varicella-Associated Stroke
A previously healthy, unimmunized 11-month-old boy presented with acute right-sided weakness. On the day of presentation, his mother noted that his right arm and leg seemed to be weak when she woke him from his usual afternoon nap. Evaluation at an urgent care center confirmed right-sided facial weakness, decreased strength and movement of his right upper and lower extremities, and a lack of right-sided support in a sitting position. Computed tomography of the head without contrast was normal. He was transferred to a regional care center where head magnetic resonance imaging and magnetic resonance angiography demonstrated ...
Source: The Journal of Pediatrics - April 19, 2018 Category: Pediatrics Authors: Surabhi B. Vora, Catherine Amlie-Lefond, Francisco A. Perez, Ann J. Melvin Tags: Insights and Images Source Type: research

Stroke May Not Mean Language Loss for Newborns
Title: Stroke May Not Mean Language Loss for NewbornsCategory: Health NewsCreated: 2/17/2018 12:00:00 AMLast Editorial Review: 2/20/2018 12:00:00 AM
Source: MedicineNet Kids Health General - February 20, 2018 Category: Pediatrics Source Type: news

Placental Pathology in Neonatal Stroke: A Retrospective Case-Control Study
To assess the association of placental abnormalities with neonatal stroke.
Source: The Journal of Pediatrics - February 4, 2018 Category: Pediatrics Authors: Miya E. Bernson-Leung, Theonia K. Boyd, Emily E. Meserve, Amy R. Danehy, Kush Kapur, Cameron C. Trenor, Laura L. Lehman, Michael J. Rivkin Tags: Original Articles Source Type: research

Striking a balance: Charlie ’s recovery from neonatal stroke
“Hey, Charlie,” says Dr. Michael Rivkin as he gently dangles a small rubber ducky in front of the little boy. “Would you like this?” A wide smile breaks out across the toddler’s face. Why yes, he certainly would like that duck. He reaches and grasps at it, closing his tiny fingers around the toy. For Charlie Strzempek, it’s nothing more than a playful act. But for his parents, Kathleen and Tom, it’s a major accomplishment. Dr. Rivkin isn’t simply offering his patient a toy. He’s testing his ability to grab and hold an object in his right hand — the side of his body affected by a neonatal stroke. A shin...
Source: Thrive, Children's Hospital Boston - December 27, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Dr. Michael Rivkin Julie Croteau occupational therapy stroke Stroke and Cerebrovascular Center Source Type: news

Bouncing back: Nolan ’s life after stroke
Although he’s only a little over a year old, Nolan Morel is a bona fide charmer. Clad in a red shirt and navy blue suspenders, he flashes a happy grin at his mother, Rosalia; his physician, Dr. Laura Lehman; and the others in the room. “Look at those dimples!” someone coos, and he giggles in response. “I can’t believe how social he’s being,” laughs Rosalia. “He wasn’t always like this.” In fact, Nolan’s first several days of life were anything but lighthearted. Just a few hours after his birth at a hospital north of Boston, he stopped breathing and had to be manually resuscitated and given oxygen. Whe...
Source: Thrive, Children's Hospital Boston - December 7, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories child life Dr. Laura Lehman feeding therapy occupational therapy physical therapy stroke Stroke and Cerebrovascular Center Source Type: news

Cadagan: Humor and tenacity after a stroke
Most parents try to discourage their children from indulging in humor about bodily functions like burping. But for Daniel and Lori Hooley, a simple smirk in response to a belch was the sign they needed that their daughter, Cadagan, was going to be okay. It was 2012 and 7-year-old Cadagan was asleep, tucked into bed for the night. Around 11 p.m., she suddenly awoke — but it wasn’t because of a nightmare or a late-night request for a glass of water. Instead, she seemed limp and couldn’t focus. Then she began throwing up. Born with an extremely rare genetic disorder called trisomy 12p, the little girl had already experi...
Source: Thrive, Children's Hospital Boston - November 20, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Dr. Cameron Trenor Dr. Laura Lehman Dr. Michael Rivkin stroke Stroke and Cerebrovascular Center vasculitis Source Type: news

Acute methotrexate-related neurotoxicity and pseudo-stroke syndrome.
We describe five episodes of transient acute leukoencephalopathy mimicking a stroke, reported in the literature as "pseudo-stroke syndrome". Neurologic symptoms occurred 3-10 days after IV or IT methotrexate and manifested as aphasia and alternating sensorimotor deficit. The fluctuating symptomatology regressed completely within a few days. Brain MRI, which is essential for diagnosis, demonstrated early white matter diffusion restriction in the affected cerebral area. These anomalies disappeared in one week, while hyperintense T2 FLAIR signals developed in the corresponding brain areas. The long-term progression of thes...
Source: Archives de Pediatrie - November 13, 2017 Category: Pediatrics Authors: Deneux V, Leboucq N, Saumet L, Haouy S, Akbaraly T, Sirvent N Tags: Arch Pediatr Source Type: research

From Buenos Aires to Boston for pediatric stroke care
Twice a year, Osvaldo and Sol board a plane in Buenos Aires, Argentina. For a week or more, they leave behind their home, their friends, their jobs — and, sometimes, their two daughters, Ines and Clara. But what waits for them, a continent away, is worth it. In Boston, they say, they have found expert care for their son, Francisco. “Francisco was perfectly fine when he was born,” says Sol. “But two days later, we were having trouble waking him up.” Although initially doctors assured the family that his behavior was normal, they quickly transferred him to the neonatal intensive care unit when he began having diffi...
Source: Thrive, Children's Hospital Boston - October 27, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Dr. Cameron Trenor Dr. Michael Rivkin International Health Services physical therapy stroke Stroke and Cerebrovascular Center Source Type: news

Michelle is moving ahead after experiencing a stroke
In fall of 2014, I was a senior, excited about finishing high school in New Hampshire and heading off to college. But I could never have guessed what the year would bring. I was an avid lacrosse player and competing in my fifth game of a tournament when I started to notice I was having trouble seeing out of my left eye. Soon, my hand felt weird and I couldn’t grip the stick properly. As I sat on the sidelines, onlookers recommended I be taken to a local hospital. Recovering from stroke I can’t remember a lot of what happened next, but I know that the emergency doctors believed I had a stroke. They sent me to the Stroke...
Source: Thrive, Children's Hospital Boston - October 2, 2017 Category: Pediatrics Authors: Michelle Ostaudelafont Tags: Diseases & Conditions Our Patients’ Stories Dr. Cameron Trenor Dr. Laura Lehman pediatric stroke Stroke and Cerebrovascular Center Source Type: news

Jacob ’s story: What it’s like to have a stroke as a kid
My name is Jacob and I’m 8 years old. Two years ago, I had a stroke. At first, I didn’t realize what that meant, and I didn’t understand why I couldn’t move the way I used to. With time, I’ve been able to get most of my function back, but my right arm has something called dystonia. That means the muscles cramp up and sometimes my arm moves on its own or gets stiff. I can’t control it, and that makes life hard sometimes. I come to Boston Children’s Hospital every few months to see Dr. Michael Rivkin at the Stroke and Cerebrovascular Center there. Nobody likes having to go to the doctor, but Dr. Rivkin is more...
Source: Thrive, Children's Hospital Boston - September 26, 2017 Category: Pediatrics Authors: Jacob Downing Tags: Diseases & Conditions Our Patients’ Stories Dr. Michael Rivkin stroke Stroke and Cerebrovascular Center Source Type: news

Athletes at risk: Knowing the dangers of heat stroke
For many young athletes, fall sports practices have already started. Whether it’s football two-a-days, soccer practices on a sweltering turf field, or cross country training in the late summer sun, the threat of heat exhaustion and heat stroke is prevalent across all sports. It’s an important time for athletes and parents to be aware of the signs of heat illnesses, especially given that children and adolescents are more susceptible to heat stroke than adults. Younger athletes produce more heat during activity, sweat less, and adjust less rapidly to changes in environmental heat. Certain sports also carry unique risks f...
Source: Thrive, Children's Hospital Boston - September 5, 2017 Category: Pediatrics Authors: Connor Ertz Tags: Ask the Expert Division of Sports Medicine Dr. Michael Beasley football heat exposure Source Type: news

Long term outcome of perinatal stroke.
Abstract Neonatal Arterial Ischemic Stroke (NAIS) affects 6-17 newborns on 100 000-birth term neonates, most of these children keeping long-term motor and cognitive impairments. Based on a literature review, the objectives of this paper are to describe motor and cognitive outcomes after a NAIS and to propose a consensual monitoring of these children to improve their management. About 30 % of children after a NAIS will develop a unilateral cerebral palsy requiring a management by a team with expertise in physical medicine and rehabilitation. Unlike adults, especially after a left NAIS, children will not present aph...
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Vuillerot C, Marret S, Dinomais M Tags: Arch Pediatr Source Type: research

Place of EEG in the management of arterial ischemic stroke newborn.
Abstract The EEG has a key role in the management of neonatal seizures, which are the typical mode of revelation of neonatal ischemic stroke. The EEG should be started as soon as possible in case of suspected seizure. Some EEG features are evocative of neonatal stroke, typically asymmetry of background activity with the presence of focal spikes and focal seizures. The EEG should be prolonged and always associated with a video as pauci-symptomatic or subclinical seizures are frequent, including some status epilepticus. Video-EEG monitoring is therefore essential to judge the efficacy of anticonvulsant therapy. Ther...
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Nguyen The Tich S Tags: Arch Pediatr Source Type: research

Biological monitoring and other explorations in the acute phase of a neonatal arterial ischemic stroke (excluding hemostasis).
Abstract Neonatal monitoring and other explorations required just after neonatal arterial ischemic stroke (NAIS) diagnosis remain elusive. This review attempts to propose guidelines on this topic. During neonatal period, three major contexts related to NAIS emerge: 1) Metabolic disorders including hypoglycemia; 2) Early post-natal infections; 3) Cardio-vascular anomalies. Different patient profiles have been defined (typical, atypical and at risk profiles). According to these profiles, a final decisional tree including biological monitoring and complementary explorations has been suggested to caregivers. PMID...
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Favrais G, Nguyen The Tich S Tags: Arch Pediatr Source Type: research

Neonatal arterial ischemic stroke in term or near-term newborns: prevalence and risk factors.
Abstract The general designation ischemic perinatal stroke includes several disease states that differ in pathophysiology, timing of occurrence and presentation. While it seems logical to assume that their prevalence and their risk factors depend primarily on the considered type of stroke, most studies used inconsistent definitions or included heterogeneous populations, which limits their accuracy. Given these biases, the French Society of Neonatology and the French Centre for Paediatric Stroke wished to update the knowledge in this domain, focusing on a specific form of perinatal stroke, i.e neonatal arterial isc...
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Darmency-Stamboul V, Cordier AG, Chabrier S Tags: Arch Pediatr Source Type: research

Neonatal arterial ischemic stroke: Which thrombotic biological risk factors to investigate and which practical consequences?
Abstract All biological risk factors that have been previously identified to increase the risk of thrombosis in adults, have also been studied in neonates with arterial Ischemic Stroke (NAIS), but most studies were retrospective and included relatively low numbers of affected children. We therefore could not suggest recommendations with a strong level of evidence and only expert proposals potentially useful for clinical practice will be presented in this text. Despite these limitations, the extensive analysis of published data supported that factor V Leiden (FVL) and increased levels of Lp(a) could be significant ...
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Perez T, Valentin JB, Saliba E, Gruel Y Tags: Arch Pediatr Source Type: research

Recommendations for imaging neonatal ischemic stroke.
Abstract Neuroimaging is critical for the diagnosis of neonatal arterial ischemic stroke (NAIS) and for prognosis estimation. The purpose of this work is to define guidelines of clinical neuroimaging for the diagnosis of NAIS, for the optimization of the imaging timing and for the assessment of the prognostic value of each imaging technique. A systematic search of electronic databases (Medline via Pubmed) for studies whose title and abstract were focused on NAIS has been conducted. One hundred and ten articles were selected and their results were analyzed by three Senior Practitioners of pediatric radiology using ...
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Husson B, Durand C, Hertz-Pannier L Tags: Arch Pediatr Source Type: research

Guidelines for the management of the cerebral arterial ischemic stroke in at term or near-term newborns.
PMID: 28867031 [PubMed - in process]
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Debillon T, de Launay C, Ego A Tags: Arch Pediatr Source Type: research

Saving Vanessa, part 1: A mystery rash, a stroke and an epic rescue
Vanessa’s rash first appeared on her arms and legs when she 3 or 4 months old. It was red and bumpy and went away when she was sick with a virus, which happened often. Then it would come back. The dermatology team she saw at Boston Children’s Hospital was puzzled. “I was expecting they were going to think it was nothing, but they took it very seriously,” says Katherine Bell, one of Vanessa’s mothers. “They took a biopsy and very quickly realized they had no idea what it was.” Vanessa’s case was even featured at a regional dermatology conference where doctors take up mystery patients. “A hundred to 150 der...
Source: Thrive, Children's Hospital Boston - July 25, 2017 Category: Pediatrics Authors: Nancy Fliesler Tags: Diseases & Conditions Our Patients’ Stories Dr. Carolyn Rogers Dr. Pui Lee Dr. Robert Sundel Dr. Scellig Stone Dr. Todd Lyons stroke Source Type: news

Kyphoscolitic Type of Ehlers-Danlos Syndrome with Prenatal Stroke.
We report two children with perinatal stroke; accompanied by neonatal joint hypermobility, hypotonia; and early development of kyphoscoliosis. OUTCOME: Molecular analysis revealed a PLOD1 gene mutation. Our definitive diagnosis was a EDS VIA. MESSAGE: Prenatal brain stroke is a rare clinical feature of EDSVIA. PMID: 28667723 [PubMed - in process]
Source: Indian Pediatrics - June 15, 2017 Category: Pediatrics Authors: Zahed-Cheikh M, Tosello B, Coze S, Gire C Tags: Indian Pediatr Source Type: research

Utility of Neurovascular Imaging in Acute Neonatal Arterial Ischemic Stroke
To evaluate the prevalence of magnetic resonance angiography (MRA) findings and clinically characterize neonates with arterial ischemic stroke (AIS) who have abnormal or variable vasculature.
Source: The Journal of Pediatrics - June 14, 2017 Category: Pediatrics Authors: Ishita Siddiq, Derek Armstrong, Ann-Marie Surmava, Nomazulu Dlamini, Daune MacGregor, Mahendranath Moharir, Rand Askalan Tags: Original Articles Source Type: research

Neonatal Arterial Ischemic Stroke – A Hospital Based Active Surveillance Study in Germany
Conclusions NAIS is a rare but not negligible morbidity in newborns. Asymptomatic children account for 56% of NAIS in all neonates. In these, not only seizures but also other unexplained symptoms should trigger diagnostic work-up with cUS and cMRI. Negative initial ultrasound results do not exclude NAIS. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Klinische Padiatrie - May 30, 2017 Category: Pediatrics Authors: Klemme, Mathias Gerstl, Lucia Weinberger, Raphael Olivieri, Martin Flemmer, Andreas von Kries, R üdiger Felderhoff-M üser, Ursula Dzietko, Mark Tags: Original Article Source Type: research

Quality of life heart-disease children who have suffered from an arterial ischemic stroke.
PMID: 28551303 [PubMed - as supplied by publisher]
Source: Anales de Pediatria - May 24, 2017 Category: Pediatrics Authors: Vázquez López M, Castro de Castro P, Gil Villanueva N, Alcaraz Romero AJ, Pascual Pascual SI Tags: An Pediatr (Barc) Source Type: research

Keeping up with Amanda: Life after brain surgery
In most ways, Amanda LePage is just like any other rambunctious fourth grader. She loves school, dance class, playing basketball and keeping up with her twin sister Macy and older brother Nathan. Sometimes it just takes her a little longer to do these everyday things. That’s because Amanda has been through a lot in her short nine years. Amanda was just 5 months old when she was brought by helicopter to Boston Children’s Hospital for a hemorrhage in her brain from an intracranial aneurysm, a type of vascular malformation. Despite long odds, Amanda survived two life-saving brain surgeries and a massive stroke that left ...
Source: Thrive, Children's Hospital Boston - May 22, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Our Patients’ Stories brain aneurysm Dr. Caroline Robson Dr. Craig McClain Dr. Edward Smith Dr. Peter Manley Hydrocephalus low-grade glioma pediatric stroke Source Type: news

Immunotherapy for arterial ischaemic stroke in childhood: a systematic review
Conclusions Immunotherapies are used in children with AIS, mainly as steroids for children with arteriopathy. However, there is currently little robust evidence to either encourage or discourage this practice. There is weak evidence consistent with the hypothesis that in certain children at risk, steroids may both reduce the risk of occurrent/recurrent stroke and enhance neurological outcomes. As the potential benefit is still uncertain, this indicates that a trial of steroids in childhood AIS may be justified.
Source: Archives of Disease in Childhood - April 19, 2017 Category: Pediatrics Authors: Edwards, H. B., Mallick, A. A., O'Callaghan, F. J. K. Tags: Clinical trials (epidemiology), Epidemiologic studies, Immunology (including allergy), Stroke, Child health Original article Source Type: research

Superhero Joey: Five-year-old fights moyamoya disease
It’s been said that not all heroes wear capes — but Joey Gallagher owns several. The five-year-old has already amassed a collection of superhero gear, from a Superman Halloween costume to a t-shirt emblazoned with the Batman logo. Yet even the most diehard comic book fan would likely admit that feats like flying, leaping tall buildings and fighting bad guys don’t hold a candle to the challenges this little boy has already surmounted. Just last June, Joey was out of town with his family when he had what his parents, Leila and Scott, feared was a seizure. Clinicians in the emergency department dismissed the event as he...
Source: Thrive, Children's Hospital Boston - April 4, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories childhood stroke Dr. Edward Smith Dr. Michael Scott moyamoya Moyamoya Disease Program Source Type: news

Understanding Brain Reorganization in Infants With Perinatal Stroke Through Neuroexcitability and Neuroimaging
Discussion: Study results will enhance our understanding of brain reorganization in infants with perinatal stroke. We expect these results will also guide the development of early interventions designed to mitigate maladaptive neuroplastic changes and improve long-term motor outcomes.
Source: Pediatric Physical Therapy - March 30, 2017 Category: Pediatrics Tags: Study Protocol Source Type: research

Question 2: Should thrombolytic agents be used in children presenting with acute ischaemic stroke?
Archimedes summaryStructured clinical question In children (1 month to 18 years) outside the neonatal age range presenting with acute ischaemic stroke (AIS), does thrombolysis help improve neurological outcome? If so, within what time frame does this need to occur in order to be effective? Outcome of evidence search Thrombolysis is not clearly of benefit in children presenting with AIS. Scenario A previously fit and well 12-year-old girl presents to accident and emergency (A&E) in the middle of the night with an acute-onset left-sided hemiparesis. She was last seen well before bed 3 hours ago. The clinic...
Source: Archives of Disease in Childhood - March 19, 2017 Category: Pediatrics Authors: Baskaran, D., Hussain, N. Tags: ADC Archimedes Source Type: research

Participatory design in the development of an early therapy intervention for perinatal stroke
Perinatal stroke is the leading cause of unilateral (hemiparetic) cerebral palsy, with life-long personal, social and financial consequences. Translational research findings indicate that early therapy interve...
Source: BMC Pediatrics - January 23, 2017 Category: Pediatrics Authors: Anna Purna Basu, Janice Elizabeth Pearse, Jessica Baggaley, Rose Mary Watson and Tim Rapley Source Type: research

Ischemic stroke in Kawasaki disease
Abstract Pediatric stroke is considered to be rare. Stroke resulting from cerebral vasculitis is also uncommon in young children. With the increasing prevalence of Kawasaki disease (KD) diagnosis, this acquired vasculitis has been reported with various clinical presentations including neurological symptoms. Herein we describe the case of a KD patient presenting with stroke. A 15‐month‐old boy was referred due to stroke that occurred on the fifth day of febrile illness. He was initially admitted to another hospital due to fever and diarrhea. He was discharged and re‐admitted 2 days afterward due to left hemiplegia. D...
Source: Pediatrics International - January 18, 2017 Category: Pediatrics Authors: Wasana Prangwatanagul, Alisa Limsuwan Tags: Patient Report Source Type: research

Characteristics, Risk Factors, and Outcomes of Neonatal Hemorrhagic Stroke
This population-based case-control study characterizes the incidence, types, presentations, associated factors, and outcomes of neonatal hemorrhagic stroke.
Source: JAMA Pediatrics - January 17, 2017 Category: Pediatrics Source Type: research

Abnormal neurodevelopmental outcomes are very likely in cases of bilateral neonatal arterial ischaemic stroke
ConclusionOur study showed that abnormal neurodevelopmental outcomes were very likely after cases of neonatal AIS with bilateral involvement and clinicians should consider early and more effective interventions in such cases.This article is protected by copyright. All rights reserved.
Source: Acta Paediatrica - October 31, 2016 Category: Pediatrics Authors: Ju Hyun Jin, Jeong Eun Shin, Soonmin Lee, Ho Sun Eun, Min Soo Park, Kook In Park, Ran Namgung Tags: Regular Article Source Type: research

Moyamoya and childhood stroke: Catching up with Tyler and Ryan
Ryan (above left) and Tyler Earle of Winnipeg, Canada had a ticking time bomb inside their heads. Both boys have a rare brain disorder called moyamoya that had caused the arteries feeding their brains to become dangerously narrowed. At first, they experienced only headaches. But then Ryan suddenly lost his ability to write, began having trouble with word-finding and became weak on one side of his body — signs he had suffered a stroke. He was diagnosed with moyamoya and had partial surgery, but a second stroke took away part of his vision and partially paralyzed him. Ryan needed a second operation as soon as possible. By ...
Source: Thrive, Children's Hospital Boston - May 12, 2016 Category: Pediatrics Authors: Nancy Fliesler Tags: Diseases & Conditions Cerebrovascular Disorders and Stroke Program Dr. Edward Smith moyamoya Source Type: news

Kelsey’s transformation: From stroke survivor to motivational speaker
“When I woke up after my stroke, all I wanted was to be normal again,” recalls Kelsey Tainsh. Normal — as in a healthy teen athlete who could brush her teeth and shower on her own, who wasn’t wheelchair-bound, who wasn’t compelled to hide her paralyzed right hand in her pocket everywhere she went, one who hadn’t lost all of her high school friends except for her two triplet sisters. Now, this world-champion athlete not only learned to walk and talk again but also to embrace her differences. “Our hardest obstacles can be our biggest opportunities,” she says. Kelsey’s first taste of being different came at ...
Source: Thrive, Children's Hospital Boston - March 16, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Our Patients’ Stories Brain tumor Mark Rockoff R. Michael Scott stroke Source Type: news

Paediatric cerebral sinovenous thrombosis: findings of the International Paediatric Stroke Study
Conclusions Our study extends the observations of previously published smaller studies in children with CSVT that this is a morbid disease with diverse underlying causes and risk factors. Divergent treatment practices among highly specialised centres as well as limited data on treatment efficacy and safety suggest that further study of this condition is warranted.
Source: Archives of Disease in Childhood - January 20, 2015 Category: Pediatrics Authors: Ichord, R. N., Benedict, S. L., Chan, A. K., Kirkham, F. J., Nowak-Gottl, U., Ashwal, deVeber, Ferriero, Fullerton, Ichord, Kirkham, Lynch, O'Callaghan, Pavlakis, Sebire, Willan, Kirton, Moharir, Sofronas, Nowak-Gottl, During, Krumpel, Dowling, Plumb, Jou Tags: Epidemiologic studies, Drugs: cardiovascular system, Epilepsy and seizures, Headache (including migraine), Pain (neurology), Stroke, Child health, Memory disorders (psychiatry) Original article Source Type: research