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An explainable machine learning method for assessing surgical skill in liposuction surgery
ConclusionOur results demonstrate the strong abilities of explainable machine learning methods in objective surgical skill assessment. We believe that the machine learning model based on interpretive methods proposed in this article can improve the evaluation and training of liposuction surgery and provide objective assessment and training guidance for other surgeries.
Source: International Journal of Computer Assisted Radiology and Surgery - November 12, 2022 Category: Intensive Care Source Type: research

E-045 A case of left internal carotid artery stroke due to fat embolism from novel cosmetic procedure: a case report
A 28-year old woman was transferred to the emergency room following an acute change in mental status after liposuction and fat harvesting transfer into her gluteal region. She had a forced left-gaze, with right sided hemiplegia where the motor movements did not even respond to painful stimulation, and Babinski’s sign was positive on both the sides. The CT brain - stroke protocol scan was 5.5 h after the liposuction procedure showed a hypoattenuation signal in the left hemisphere and a hypodensity within the left Sylvian fissure, signs of grey-white matter differentiation, with 1mm MLS to the right. NIHSS on admission...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Raza, D. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Adipose tissue derived stromal vascular fraction as an adjuvant therapy in stroke rehabilitation: Case reports
Introduction: Stroke often causes residual hemiparesis, and upper extremity motor impairment is usually more disabling than lower extremity in those who are suffering from post-stroke hemiparesis. Cell therapy is one of the promising therapies to reduce post-stroke disability. Patient concerns: Three male participants were included in the study to investigate the feasibility and tolerability of autologous adipose tissue derived stromal vascular fraction. Diagnosis: All participants had hemiparesis after 1st-ever stroke longer than 6 months previously. Interventions: Under general anesthesia, liposuction of abdom...
Source: Medicine - August 21, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Concise Review: Using Fat to Fight Disease: A Systematic Review of Nonhomologous Adipose ‐Derived Stromal/Stem Cell Therapies
The objective of this Review is to describe the safety and efficacy of adipose stem/stromal cells (ASC) and stromal vascular fraction (SVF) in treating common diseases and the next steps in research that must occur prior to clinical use. Pubmed, Ovid Medline, Embase, Web of Science, and the Cochrane Library were searched for articles about use of SVF or ASC for disease therapy published between 2012 and 2017. One meta ‐analysis, 2 randomized controlled trials, and 16 case series were included, representing 844 human patients. Sixty‐nine studies were performed in preclinical models of disease. ASCs improved symptoms, fi...
Source: Stem Cells - September 5, 2018 Category: Stem Cells Authors: Marjorie E. Bateman, Amy L. Strong, Jeffrey M. Gimble, Bruce A. Bunnell Tags: Regenerative Medicine Source Type: research

Intravenous Alteplase for Acute Stroke and Pulmonary Embolism in a Patient With Recent Abdominoplasty
Conclusions: Interdisciplinary collaboration can successfully inform the decision to treat acute ischemic stroke with IV alteplase in the setting of recent major surgery.
Source: The Neurologist - June 24, 2017 Category: Neurology Tags: Case Report/Case Series Source Type: research

Change to Australasian College of Sport and Exercise Physicians--position statement: the place of mesenchymal stem/stromal cell therapies in sport and exercise medicine
The Board of the Australasian College of Sport and Exercise Physicians has recently learnt concerns of the Australian Government, other medical colleges and our own fellowship regarding the safety of procedures involved with the provision of stem cell therapy to patients. These concerns are partially driven by reports recently published in the lay media, scientific literature and a coroner’s report. A recent case report in the New England Journal of Medicine1 of a glioproliferative tumour in the spine after treatment with a mixture of mesenchymal, embryonic and fetal allogeneic stem cells for residual effects of a st...
Source: British Journal of Sports Medicine - September 29, 2016 Category: Sports Medicine Authors: Osborne, H., Castricum, A. Tags: Editorial Source Type: research

Assessment of college students' awareness and knowledge about conditions relevant to metabolic syndrome.
CONCLUSION: The findings in this study suggest that students' knowledge about conditions relevant to metabolic syndrome can be improved. In this essence, raising awareness about MetS based on students' pre-existing knowledge is essential to enhance students' wellness. PMID: 25360161 [PubMed]
Source: Diabetes Metab - November 4, 2014 Category: Endocrinology Authors: Yahia N, Brown C, Rapley M, Chung M Tags: Diabetol Metab Syndr Source Type: research

Proteomic Analysis of Mature Adipocytes from Obese Patients in Relation to Aging.
In conclusion, proteomic analysis of subcutaneous adipose tissue reveals differences in the abundance of proteins in adipocytes isolated from young vs. old individuals. These differentially abundant proteins are involved in the regulation of apoptosis, cellular senescence and inflammatory response. All these are common pathologic events in both obesity and aging. PMID: 23886751 [PubMed - as supplied by publisher]
Source: Experimental Gerontology - July 22, 2013 Category: Geriatrics Authors: Alfadda AA, Benabdelkamel H, Masood A, Moustafa A, Sallam R, Bassas A, Duncan M Tags: Exp Gerontol Source Type: research

Fat chance: Scientists unexpectedly discover stress-resistant stem cells in adipose tissue
Researchers from the UCLA Department of Obstetrics and Gynecology have isolated a new population of primitive, stress-resistant human pluripotent stem cells that are easily derived from fat tissue and are able to differentiate into virtually every cell type in the human body without genetic modification.   The cells, called multi-lineage stress-enduring stem cells from adipose tissue (Muse-AT), were discovered by "scientific accident" when a piece of equipment failed in the laboratory, killing all the stem cells in an experiment except the Muse-AT cells.   The UCLA team further discovered that not only are Muse-A...
Source: UCLA Newsroom: Health Sciences - June 5, 2013 Category: Universities & Medical Training Source Type: news