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Rural-urban and geographical differences in prognosis of atrial fibrillation in Finland: a nationwide cohort study
CONCLUSIONS: Rural-urban differences in prognosis of AF in Finland appear minimal, whereas considerable disparities exist between HDs.PMID:37571929 | DOI:10.1177/14034948231189918
Source: Scandinavian Journal of Public Health - August 12, 2023 Category: International Medicine & Public Health Authors: Konsta Teppo K E Juhani Airaksinen Olli Halminen Jussi Jaakkola Miika Linna Jari Haukka Jukka Putaala Pirjo Mustonen Janne Kinnunen Juha Hartikainen Mika Lehto Source Type: research

Mobile point-of-care MRI demonstration of a normal volunteer in a telemedicine-equipped ambulance
Several centers have implemented ambulances equipped with CT scanners and telemedicine capabilities, known as mobile stroke units (MSU), to expedite acute stroke care delivery in the pre-hospital setting. While MSUs have been shown to improve outcomes compared with standard emergency medical management, there are limitations to incorporating CT, including radiation exposure to emergency medical services personnel. Recently, a portable, low-field strength MRI (Swoop ®, Hyperfine, Inc., Guilford, CT) received FDA clearance for in-hospital use.
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2023 Category: Neurology Authors: Donna R. Roberts, Todd McGeorge, Dave Abrams, Russell Hewitt, Dustin LeBlanc, William Dennis, Mark Rosenberg, Sami Al Kasab, Christine Holmstedt, Maria V. Spampinato, Sam Torres-Rosado, Richard Ancrum, Michael Haschker, Jillian Harvey Source Type: research

Effect of arteriosclerotic intracranial arterial vessel wall enhancement on downstream collateral flow
CONCLUSIONS: Arteriosclerotic IAVWE significantly reduced downstream collateral flow and affected relevant neurological deficits. It was an independent factor affecting downstream collateral flow and NIHSS scores, which should be a focus of future studies.TRIAL REGISTRATION: ChiCTR.org.cn, ChiCTR2100053661.PMID:37545035 | DOI:10.1097/CM9.0000000000002307
Source: Chinese Medical Journal - August 7, 2023 Category: General Medicine Authors: Liqun Yan Zhenchang Wang Guoshi Wang Zhenzhong Li Jin Yan Yaping Hou Boyuan Huang Qianbo Dong Xiaodan Mu Wei Cao Pengfei Zhao Source Type: research

Quiz case: a clinical reasoning challenge in the emergency stroke setting
AbstractA right-handed woman in her 80s was admitted to the emergency department 1 h after sudden-onset global aphasia and right-sided hemiparesis. Medical history included arterial hypertension, dyslipidemia, hyperuricemia, aortic stenosis, osteoporosis, and recent pulmonary embolism. Medication consisted of apixaban, bisoprolol, hydrochlorothiazide, allopurinol, fenofibrate, and vitamin D. Vital parameters (blood pressure, heart rate, body temperature, oxygen saturation) and glycemia were all within normal range. Electrocardiogram showed a first-degree atrioventricular block. The patient was promptly transported to the e...
Source: Neurological Sciences - August 5, 2023 Category: Neurology Source Type: research

Establishing minimally important differences for cardiac MRI end-points in pulmonary arterial hypertension
Conclusions This study establishes clinically relevant CMR MIDs for how a patient "feels, functions or survives" in response to PAH treatment. These findings provide further support for the use of CMR as a clinically relevant clinical outcome measure and will aid trial size calculations for studies using CMR.
Source: European Respiratory Journal - August 3, 2023 Category: Respiratory Medicine Authors: Alabed, S., Garg, P., Alandejani, F., Dwivedi, K., Maiter, A., Karunasaagarar, K., Rajaram, S., Hill, C., Thomas, S., Gossling, R., Sharkey, M. J., Salehi, M., Wild, J. M., Watson, L., Hameed, A., Charalampopoulos, A., Lu, H., Rothman, A. M. K., Thompson, Tags: Pulmonary vascular disease Original Articles: Pulmonary vascular disease Source Type: research

E-115 Trans-radial versus trans-femoral access routes for diagnostic cerebral angiograms: a large single-center comparative cost-analysis study
ConclusionOverall, our study shows that the TR approach can be less a less expensive option for patients undergoing diagnostic cerebral angiograms, especially if complications occur. Future studies can corroborate our findings and potentially lead to the adoption of TR as a low-cost, efficient, gold-standard technique for cerebral angiography.Costs (dollars) Associated with Trans-Radial Versus Trans-Femoral AccessAbstract E-115 Table 1 Variable Trans-Femoral (n=314) Trans-Radial(n=612) P-value Total Cost, mean (SD) 12591.8 (19128) 12789.5 (18424) .88 Catheters, median (range) 12.4 (12.4-1900) 55.2 (12.4-369) .03 Closure d...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Atallah, E., Momin, A., Jain, P., Hunt, A., Sambangi, A., Carreras, A., El Fadel, O., Gooch, M., Tjoumakaris, S., Zarzour, H., Schmidt, R., Herial, N., Rosenwasser, R., Jabbour, P. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

O-017 Viz LVO versus rapid LVO in detection of large vessel occlusion on computed tomography angiography for acute stroke
ConclusionViz LVO and Rapid LVO had similar NPV, but Rapid LVO produced a significantly larger number of false positive values. False positive values can be a source of alarm desensitization, leading to missed alarms or delayed responses. EF and intracranial atherosclerosis were significant predictors of incorrect predictions in both software packages. We hope this data will be used to improve future algorithms.Disclosures A. Delora: None. C. Hadjialiakbari: None. E. Percenti: None. A. Hassan: 1; C; LVO SYNCHRONIZE-Viz.ai. 2; C; Viz.ai. Y. Alderazi: None. J. Torres: None. M. Ezzeldin: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Delora, A., Hadjialiakbari, C., Percenti, E., Hassan, A., Alderazi, Y., Torres, J., Ezzeldin, M. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-223 Improved time to diagnosis with portable MR imaging
ConclusionPortable MRI is a promising innovation with the aim to expand patient access and improve diagnostic times so that critical and potential lifesaving imaging diagnoses can be promptly treated with the urgency that is required. While initial analysis provides evidence that portable MRI has advantages over conventional MRI systems including workflow efficiency and improved patient imaging times, this will need to be compared to the unfortunate negative drawbacks of lessened image resolution and limited imaging sequences that come with the convenience of portable MRI systems. If the hypothesis is further corroborated,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Richardson, O., Richardson, A., Mukherjee, S. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

A randomized controlled trial of Changes in resting-state functional connectivity associated with short-term motor learning of chopstick use with the non-dominant hand
CONCLUSION]: Offline enhancement of RSFC in these networks was shown to contribute to early chopstick-use motor learning with the left hand. These results serve as a basis for future studies on compensatory networks in individuals with stroke.PMID:37506851 | DOI:10.1016/j.bbr.2023.114599
Source: Brain Research - July 28, 2023 Category: Neurology Authors: Sayori Takeda Reiko Miyamoto Source Type: research

Percutaneous left atrial appendage closure in patients with gastrointestinal bleeding associated with oral anticoagulants
CONCLUSIONS: LAAC could be a safe and effective alternative to OAC in patients with non-valvular AF presenting significant, recurrent or potentially unresolvable GIB. This intervention also leads to important savings in the consumption of healthcare resources.PMID:37489111 | DOI:10.1080/00365521.2023.2239973
Source: Scandinavian Journal of Gastroenterology - July 25, 2023 Category: Gastroenterology Authors: Patricia Sanz Segura Javier Jimeno S ánchez Jos é Miguel Arbonés-Mainar Juan S ánchez-Rubio Lezcano Gabriel Galache Osuna Vanesa Bernal Monterde Source Type: research