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Total 6091 results found since Jan 2013.

White Matter Microstructural Alterations over the Year after Acute Ischemic Stroke in Patients with Baseline Impaired Cognitive Functions
CONCLUSION: The finding suggests that the patients with baseline impaired cognitive functions still have WM microstructural damages at 1 year poststroke, even if their cognitive function has improved or returned to normal. Cautions should be taken against the possible negative impact of these changes on long-term cognition.PMID:37456365 | PMC:PMC10348854 | DOI:10.1155/2023/6762225
Source: Neural Plasticity - July 17, 2023 Category: Neurology Authors: Bingyuan Wu Shida Guo Xiuqin Jia Zuojun Geng Qi Yang Source Type: research

Incidental findings on FDG-PET/CT in large vessel vasculitis
This study aims to determine the number and type of incidental findings detected on positron emission tomography (PET)/CT in a cohort of patients with large vessel vasculitis (LVV). Reports from PET/CT studies along with the medical charts of a cohort of patients with LVV from a Rheumatology clinic in Edmonton, Alberta, Canada, were retrospectively reviewed. Incidental findings from PET/CT, along with follow-up studies and their diagnosis were documented. The data was analyzed with descriptive statistics. The disease activity of 40 patients, with an average age of 65.8  years, was investigated using PET/CT. A statisticall...
Source: Clinical Rheumatology - July 13, 2023 Category: Rheumatology Source Type: research

Noninvasive In Vivo Thrombus Imaging in Patients With Ischemic Stroke or Transient Ischemic Attack
CONCLUSIONS: 18F-GP1 positron emission tomography and computed tomography angiography is a novel noninvasive method of identifying in vivo cerebrovascular thrombosis, which holds major promise in understanding the role and origin of thrombosis in stroke.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT03943966.PMID:37439259 | DOI:10.1161/ATVBAHA.122.318204
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 13, 2023 Category: Cardiology Authors: Beth Whittington Evangelos Tzolos Rong Bing Jack Andrews Christophe Lucatelli Mark G MacAskill Adriana A S Tavares Tim Clark Nicholas L Mills Jennifer Nash Damini Dey Piotr J Slomka Norman Koglin Andrew W Stephens Edwin J R van Beek Colin Smith Marc R Dwe Source Type: research

Sodium Tanshinone IIA Sulfonate Ameliorates Oxygen-glucose Deprivation/Reoxygenation-induced Neuronal Injury via Protection of Mitochondria and Promotion of Autophagy
Neurochem Res. 2023 Jul 12. doi: 10.1007/s11064-023-03985-x. Online ahead of print.ABSTRACTSodium tanshinone IIA sulfonate (STS) has shown significant clinical therapeutic effects in cerebral ischemic stroke (CIS), but the molecular mechanisms of neuroprotection remain partially known. The purpose of this study was to explore whether STS plays a protective role in oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by regulating microglia autophagy and inflammatory activity. Co-cultured microglia and neurons were subjected to OGD/R injury, an in vitro model of ischemia/reperfusion (I/R) injury with or ...
Source: Neurochemical Research - July 12, 2023 Category: Neuroscience Authors: Zhi Ma Yue Wu Juan Xu Hui Cao Mingyang Du Haibo Jiang Feng Qiu Source Type: research

Neurofunctional correlates of a neurorehabilitation system based on eye movements in chronic stroke impairment levels: A pilot study
ConclusionThese promising results have a potential application as a new game-based neurorehabilitation approach to enhance the motor activity of stroke patients.
Source: Brain and Behavior - July 12, 2023 Category: Neurology Authors: B árbara R. García‐Ramos, Rebeca Villarroel, José L. González‐Mora, Consuelo Revert, Cristián Modroño Tags: ORIGINAL ARTICLE Source Type: research

Improving door-to-reperfusion time in acute ischemic stroke during the COVID-19 pandemic: experience from a public comprehensive stroke center in Brazil
ConclusionAcute stroke care continued to be a priority despite the COVID-19 pandemic. The implementation of a thrombolytic bolus and the start of continuous infusion on the CT scan table was the main factor that contributed to the reduction of DNT. Continuous monitoring of service times is essential for improving the quality of the stroke center and achieving better functional outcomes for patients.
Source: Frontiers in Neurology - July 10, 2023 Category: Neurology Source Type: research

Improved language function for post-stroke aphasia in the long term following repeated repetitive transcranial magnetic stimulation and intensive speech-language-hearing therapy: a case report
ConclusionsThe findings of the study indicate that the repeated use of repetitive transcranial magnetic stimulation and intensive speech-language-hearing therapy may be effective in improving and preserving language function and increasing cerebral blood flow for aphasia following stroke.
Source: Journal of Medical Case Reports - July 8, 2023 Category: General Medicine Source Type: research

Establishing minimally important differences for cardiac MRI endpoints in pulmonary arterial hypertension
CONCLUSION: This study establishes clinically relevant CMR MIDs for how a patient feels, functions or survives in response to PAH treatment. These findings provide further support for the use of CMR as a clinically relevant clinical outcome measure and will aid trial-size calculations for studies using CMR.PMID:37414419 | DOI:10.1183/13993003.02225-2022
Source: Respiratory Care - July 6, 2023 Category: Respiratory Medicine Authors: Samer Alabed Pankaj Garg Faisal Alandejani Krit Dwivedi Ahmed Maiter Kavita Karunasaagarar Smitha Rajaram Catherine Hill Steven Thomas Rebecca Gossling Michael Sharkey Mahan Salehi Jim M Wild Lisa Watson Abdul Hameed Athanasios Charalampopoulos Haiping Lu Source Type: research