Query: stroke

Filtered By:
Procedure: Heart Valve Surgery

This page shows you your search results in order of date. This is page number 11.

Order by Relevance | Date

Total 1215 results found since Jan 2013.

Outcomes of intermediate ‐risk patients treated with transcatheter and surgical aortic valve replacement in the Veterans Affairs Healthcare System: A single center 20‐year experience
ConclusionsAdoption of TAVR as the preferred treatment modality in intermediate‐risk patients may result in significant improvements in morbidity and mortality.
Source: Catheterization and Cardiovascular Interventions - January 9, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Santiago Garcia, Rosemary Kelly, Mackenzie Mbai, Sergey Gurevich, Brett Oestreich, Demetris Yannopoulos, Selcuk Adabag Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Comparing Methods for Cardiac Output: Intraoperatively Doppler-Derived Cardiac Output Measured With 3-Dimensional Echocardiography Is Not Interchangeable With Cardiac Output by Pulmonary Catheter Thermodilution.
CONCLUSIONS: Despite low bias, the wide limits of agreement of Doppler-derived CO by 3D TEE compared to CO by thermodilution will limit clinical application and can therefore not be considered interchangeable with CO obtained by thermodilution. The lack of agreement is not explained by lack of agreement of the 3D technique. PMID: 29324489 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - January 9, 2018 Category: Anesthesiology Authors: Graeser K, Zemtsovski M, Kofoed KF, Winther-Jensen M, Nilsson JC, Kjaergaard J, Møller-Sørensen H Tags: Anesth Analg Source Type: research

Long-Term Results of Aortic Root Surgery in Marfan Syndrome Patients: A Single-Center Experience.
CONCLUSIONS: The Bentall and David operations are both associated with satisfactory long-term results in MFS patients. The low rate of valve prosthesis-related complications suggested that the Bentall operation would continue to be a standard surgical treatment. The reimplantation technique, adopted for less-dilated aortas, provides satisfactory freedom from reoperation. Careful attention should be paid to the reimplantation technique in patients affected by a serious familiar genetic phenotype. PMID: 29302938 [PubMed - in process]
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Nonvitamin K Antagonist Oral Anticoagulants Use in Patients with Atrial Fibrillation and Bioprosthetic Heart Valves/Prior Surgical Valve Repair: A Multicenter Clinical Practice Experience
Semin Thromb Hemost DOI: 10.1055/s-0037-1615261This is an observational study to investigate the efficacy and safety of nonvitamin K antagonist oral anticoagulants (NOACs) in atrial fibrillation (AF) patients with bioprosthetic valves or prior surgical valve repair in clinical practice. A total of 122 patients (mean age: 74.1 ± 13.2; 54 females) with bioprosthetic heart valve or surgical valve repair and AF treated with NOACs were included in the analysis. The mean CHA2DS2-VASc (Congestive heart failure, Hypertension, Age >75 years, Diabetes mellitus, prior Stroke or transient ischemic attack, Vascular disease) and...
Source: Seminars in Thrombosis and Hemostasis - January 5, 2018 Category: Hematology Authors: Russo, Vincenzo Attena, Emilio Mazzone, Carmine Esposito, Francesca Parisi, Valentina Bancone, Ciro Rago, Anna Nigro, Gerardo Sangiuolo, Raffaele D' Onofrio, Antonio Tags: Original Article Source Type: research

Suprasternal Transcatheter Aortic Valve Replacement in Patients With Marginal Femoral Access
Conclusions These data demonstrate the early clinical feasibility of suprasternal transcatheter aortic valve replacement. Key advantages of this approach include direct access to the innominate artery and ascending aorta, precise sheath control, and confident arterial closure. Additional experience is warranted to confirm these favorable results.
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - January 1, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

Transcatheter Aortic Valve Replacement: OPTIMIZING OUTCOMES FOR HEALTHY RECOVERY
Transcatheter aortic valve replacement (TAVR) has been approved in the United States for intermediate and high-risk patients with severe symptomatic aortic stenosis. More than 80 000 TAVR procedures have been performed in the United States and the number is growing every year. Two valve designs are approved in the United States including the balloon expandable Edwards Sapien prosthesis and self-expanding CoreValve prosthesis. The PARTNER trial of the Sapien valve, involving patients who were considered inoperable, reported a 19% absolute risk reduction in mortality compared with medical therapy, with a number needed to tre...
Source: Journal of Cardiopulmonary Rehabilitation - January 1, 2018 Category: Rehabilitation Tags: Invited Review Source Type: research

Aortic versus carotid intima ‐media thickness and impact of aortic valve disease
ConclusionsThe correlation between CIMT and AoIMT is weaker in patients with sAVD compared to those without sAVD. Pmean is also a significant predictor of AoIMT, but not of CIMT. This implies that, in addition to the atherosclerotic process, turbulent aortic flow or altered blood flow helicity created by large stroke volumes and diastolic flow reversal or high‐velocity jets, affect the intima‐media of the descending aorta and common carotid artery differently.
Source: Clinical Physiology and Functional Imaging - January 1, 2018 Category: Radiology Authors: Johan Petrini, Margareta Ring, Anders Franco ‐Cereceda, Kenneth Caidahl, Maria J. Eriksson Tags: Original Article Source Type: research

1-Year Clinical Outcomes in Women After Transcatheter Aortic Valve Replacement: Results From the First WIN-TAVI Registry
Conclusions Intermediate to high-risk women enrolled in this first ever all-women contemporary TAVR registry experienced a 1-year VARC-2 composite efficacy endpoint of 16.5%, with a low incidence of 1-year mortality and stroke. Prior revascularization and EuroSCORE I were independent predictors of the VARC-2 efficacy endpoint, whereas EuroSCORE I, baseline atrial fibrillation, and prior percutaneous coronary intervention were independent predictors of the 1-year death or stroke.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - January 1, 2018 Category: Cardiology Authors: Chieffo, A., Petronio, A. S., Mehilli, J., Chandrasekhar, J., Sartori, S., Lefevre, T., Presbitero, P., Capranzano, P., Tchetche, D., Iadanza, A., Sardella, G., Van Mieghem, N. M., Meliga, E., Dumonteil, N., Fraccaro, C., Trabattoni, D., Mikhail, G., Shar Tags: Focus on Cardiovascular Outcomes Among Women Source Type: research

Sex-Specific Outcomes of Transcatheter Aortic Valve Replacement With the SAPIEN 3 Valve: Insights From the PARTNER II S3 High-Risk and Intermediate-Risk Cohorts
Conclusions The study found no apparent sex-specific differences in survival or stroke in this trial of TAVR. This may reflect the changing demographic of patients enrolled, use of newer-generation valves with more sizes available, and more accurate valve sizing techniques.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - January 1, 2018 Category: Cardiology Authors: Szerlip, M., Gualano, S., Holper, E., Squiers, J. J., White, J. M., Doshi, D., Williams, M. R., Hahn, R. T., Webb, J. G., Svensson, L. G., Kirtane, A. J., Cohen, D. J., Douglas, P. S., Alu, M. C., Crowley, A., Tuzcu, E. M., Makkar, R. R., Herrmann, H. C., Tags: Focus on Cardiovascular Outcomes Among Women Source Type: research

Long-Term Outcomes With Transcatheter Aortic Valve Replacement in Women Compared With Men: Evidence From a Meta-Analysis
Conclusions Despite a higher upfront risk of complications, women derive a better long-term survival after TAVR compared with men.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - January 1, 2018 Category: Cardiology Authors: Saad, M., Nairooz, R., Pothineni, N. V. K., Almomani, A., Kovelamudi, S., Sardar, P., Katz, M., Abdel-Wahab, M., Bangalore, S., Kleiman, N. S., Block, P. C., Abbott, J. D. Tags: MOC Source Type: research

Cerebral Perfusion Monitoring in Adult Patients Following Cardiac Surgery: An Observational Study.
CONCLUSIONS: The prevalence of low cerebral oximetry values underscores the importance of increasing the sensitivity of monitoring tools. Further evaluation is required to assess the value of this modality and the role of nurses in optimizing neurocognitive outcomes. PMID: 29284341 [PubMed - as supplied by publisher]
Source: Contemporary Nurse - December 30, 2017 Category: Nursing Tags: Contemp Nurse Source Type: research

Initial experience with percutaneous edge-to-edge transcatheter mitral valve repair in a tertiary medical center in Taiwan
Conclusion Trans-catheter edge-to-edge mitral valve repairs are safe and effective in Asians with symptomatic SMR, regarding the improvements of clinical symptoms and exercise capacities. MitraClips is also associated with reverse remodeling of pulmonary hypertension and left ventricular size in patients with SMR.
Source: Journal of the Chinese Medical Association - December 29, 2017 Category: General Medicine Source Type: research

Transcatheter Aortic Valve Replacement: OPTIMIZING OUTCOMES FOR HEALTHY RECOVERY
Transcatheter aortic valve replacement (TAVR) has been approved in the United States for intermediate and high-risk patients with severe symptomatic aortic stenosis. More than 80 000 TAVR procedures have been performed in the United States and the number is growing every year. Two valve designs are approved in the United States including the balloon expandable Edwards Sapien prosthesis and self-expanding CoreValve prosthesis. The PARTNER trial of the Sapien valve, involving patients who were considered inoperable, reported a 19% absolute risk reduction in mortality compared with medical therapy, with a number needed to tre...
Source: Journal of Cardiopulmonary Rehabilitation - December 28, 2017 Category: Rehabilitation Tags: Invited Review Source Type: research

Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement.
CONCLUSIONS: In this series, TOTAL with MHCA and ACP can be safely performed with acceptable operative risk. MHCA and ACP represent an effective strategy for TOTAL and may obviate the need for DHCA. PMID: 29167026 [PubMed - indexed for MEDLINE]
Source: The Annals of Thoracic Surgery - December 28, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Keeling WB, Tian DH, Leshnower BG, Numata S, Hughes GC, Matalanis G, Okita Y, Yan TD, Kouchoukos N, Chen EP, IAASSG Investigators Tags: Ann Thorac Surg Source Type: research

Minimally invasive aortic valve replacement with sutureless valves
ConclusionsThe combination of minimally invasive AVR and sutureless technology has been associated with excellent results; therefore, SU-AVR might be considered the real “alternative” to TAVI procedure for high-risk patients.
Source: Indian Journal of Thoracic and Cardiovascular Surgery - December 27, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Left ventricular outflow tract shape after aortic valve replacement with St. Jude Trifecta prosthesis
ConclusionsIn supra‐annular AVR, LVOT retains its elliptical shape and LVOTCSA yielded larger prosthesis EOA with lower PPM incidence. PPM may be overestimated by EOAV.
Source: Echocardiography - December 22, 2017 Category: Cardiology Authors: Giuseppe Barletta, Francesco Venditti, Pierluigi Stefano, Riccarda Del Bene, Carlo Di Mario Tags: ORIGINAL INVESTIGATION Source Type: research

Prognostic Implications of Magnetic Resonance - Derived Quantification in Asymptomatic Patients with Organic Mitral Regurgitation: Comparison with Doppler Echocardiography-Derived Integrative Approach.
Conclusions -The findings of the present study suggest that the MRI-derived assessment of OMR can better identify patients with severe OMR and adverse outcome than ECHO-derived integrative approach warranting close follow-up and perhaps, early mitral valve surgery. PMID: 29269390 [PubMed - as supplied by publisher]
Source: Circulation - December 21, 2017 Category: Cardiology Authors: Penicka M, Vecera J, Mirica DC, Kotrc M, Kockova R, Van Camp G Tags: Circulation Source Type: research

Treatment and discharge patterns among patients hospitalized with non-valvular atrial fibrillation transitioning from the inpatient to outpatient setting.
CONCLUSIONS: Most patients hospitalized for NVAF were discharged to home support, and the majority did not have OAC treatment during hospitalization or the 30 days post-discharge. Additional investigation should be conducted on trends beyond 30 days post hospitalization and the reasons for not receiving anticoagulation therapy in patients at moderate to severe risk of stroke or systemic embolism. Helping to avoid preventable strokes is an important goal for public health. PMID: 29235900 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - December 15, 2017 Category: Research Tags: Curr Med Res Opin Source Type: research

Bioprosthetic aortic valve leaflet thrombosis detected by multidetector computed tomography is associated with adverse cerebrovascular events: a meta-analysis of observational studies.
CONCLUSIONS: MDCT-defined LT following ABV replacement is associated with a significantly increased risk of adverse cerebrovascular events. Further prospective studies are required to ascertain whether LT can be prevented or treated with pharmacological strategies. PMID: 29235436 [PubMed - as supplied by publisher]
Source: EuroIntervention - December 15, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Transcatheter Aortic Valve Replacement: OPTIMIZING OUTCOMES FOR HEALTHY RECOVERY.
Abstract Transcatheter aortic valve replacement (TAVR) has been approved in the United States for intermediate and high-risk patients with severe symptomatic aortic stenosis. More than 80 000 TAVR procedures have been performed in the United States and the number is growing every year. Two valve designs are approved in the United States including the balloon expandable Edwards Sapien prosthesis and self-expanding CoreValve prosthesis. The PARTNER trial of the Sapien valve, involving patients who were considered inoperable, reported a 19% absolute risk reduction in mortality compared with medical therapy, with a ...
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - December 14, 2017 Category: Rehabilitation Authors: Goel K, Holmes DR Tags: J Cardiopulm Rehabil Prev Source Type: research

One ‐stage ascending‐to‐abdominal aortic bypass with concomitant aortic valve procedures for aortic coarctation combined with aortic valve pathology in adult patients
ConclusionAscending‐to‐abdominal aortic bypass and concomitant aortic valve procedures are a suitable therapeutic option for severe aortic coarctation combined with aortic valve pathology in adult patients.
Source: Journal of Cardiac Surgery - December 12, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Ren Changwei, Lizhong Sun, Shangdong Xu, Yongqiang Lai Tags: ORIGINAL ARTICLE Source Type: research

Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement
Conclusions In this series, TOTAL with MHCA and ACP can be safely performed with acceptable operative risk. MHCA and ACP represent an effective strategy for TOTAL and may obviate the need for DHCA.
Source: The Annals of Thoracic Surgery - December 10, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Postoperative Reverse Remodeling and Symptomatic Improvement in Normal-Flow Low-Gradient Aortic Stenosis After Aortic Valve Replacement Valvular Heart Disease
Conclusions— Patients with NFLG had less severe AS and LV remodeling than patients with normal-flow high-gradient. Furthermore, NFLG patients experienced less reverse remodeling but the same symptomatic benefit. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02316587.
Source: Circulation: Cardiovascular Imaging - December 8, 2017 Category: Radiology Authors: Carter-Storch, R., Moller, J. E., Christensen, N. L., Irmukhadenov, A., Rasmussen, L. M., Pecini, R., Ovrehus, K. A., Sondergard, E. V., Marcussen, N., Dahl, J. S. Tags: Valvular Heart Disease, Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Source Type: research

Thirty-Day Outcomes in 100 Consecutive Patients Undergoing Transfemoral Aortic Valve Replacement With the Portico Valve on an All-Comer Basis.
CONCLUSIONS: Our immediate and 30-day post-TAVR results support favorable survival comparable to other studies, and significant clinical improvement with the Portico valve in non-selected patients in a real-world setting, with short-term complications being uncommon. PMID: 29207365 [PubMed - in process]
Source: The Journal of Invasive Cardiology - December 6, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Improvement in Aortic Valve Area in Patients With Aortic Stenosis Through Use of a New "Hourglass-Shaped" Valvuloplasty Balloon.
CONCLUSIONS: Use of the hourglass-shaped balloons provided larger AVA, as compared with use of cylindrical balloons. Use of the novel balloons was not associated with an increase in AI, PPM, or major adverse events. PMID: 29207363 [PubMed - in process]
Source: The Journal of Invasive Cardiology - December 6, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Evolution of Simplified Frozen Elephant Trunk Repair for Acute DeBakey Type I Dissection: Midterm Outcomes
Conclusions Simplified FET for treating acute DeBakey type I dissection has evolved and remained safe. It promotes aortic remodeling, and simplifies management of chronic aortic complications.
Source: The Annals of Thoracic Surgery - December 6, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Evolution of Simplified Frozen Elephant Trunk Repair for Acute DeBakey Type I Dissection: Midterm Outcomes.
CONCLUSIONS: Simplified FET for treating acute DeBakey type I dissection has evolved and remained safe. It promotes aortic remodeling, and simplifies management of chronic aortic complications. PMID: 29217087 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - December 4, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Roselli EE, Idrees JJ, Bakaeen FG, Tong MZ, Soltesz EG, Mick S, Johnston DR, Eagleton MJ, Menon V, Svensson LG Tags: Ann Thorac Surg Source Type: research

Elective David I Procedure Has Excellent Long-Term Results: 20-Year Single-Center Experience
Conclusions The valve-sparing David I procedure has excellent short- and long-term results. Erosion due to supposed leaflet contact with the straight tube graft was not observed in any patient, proving that using a straight graft has no negative impact on the leaflets. The “spared valve” (being native living tissue) seems to be more resistant to infection than prosthetic valves.
Source: The Annals of Thoracic Surgery - December 2, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

The safety of concomitant transcatheter aortic valve replacement and percutaneous coronary intervention: A systematic review and meta-analysis
Conclusion: These data did not show a significant difference in short-term outcomes between concomitant PCI and TAVR versus staged PCI and TAVR.
Source: Medicine - December 1, 2017 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Elective David I Procedure Has Excellent Long-Term Results: 20-Year Single-Center Experience.
CONCLUSIONS: The valve-sparing David I procedure has excellent short- and long-term results. Erosion due to supposed leaflet contact with the straight tube graft was not observed in any patient, proving that using a straight graft has no negative impact on the leaflets. The "spared valve" (being native living tissue) seems to be more resistant to infection than prosthetic valves. PMID: 29198631 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - December 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Shrestha ML, Beckmann E, Abd Alhadi F, Krueger H, Meyer-Bockenkamp F, Bertele S, Koigeldiyev N, Kaufeld T, Fleissner F, Korte W, Schmitto J, Cebotari S, Harringer W, Haverich A, Martens A Tags: Ann Thorac Surg Source Type: research

Assessment of Commonly Used Frailty Markers for High- and Extreme-Risk Patients Undergoing Transcatheter Aortic Valve Replacement.
CONCLUSIONS: Among high- and extreme-risk patients undergoing TAVR, our new frailty model was more discriminative of 30-day mortality than The Society of Thoracic Surgeons predicted risk of mortality. New cutoff values for frailty indicators were identified and will require further validation. PMID: 28942076 [PubMed - indexed for MEDLINE]
Source: The Annals of Thoracic Surgery - December 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Forcillo J, Condado JF, Ko YA, Yuan M, Binongo JN, Ndubisi NM, Kelly JJ, Babaliaros V, Guyton RA, Devireddy C, Leshnower BG, Stewart JP, Perrault LP, Khairy P, Thourani VH Tags: Ann Thorac Surg Source Type: research

Transapical Mitral Valve Implantation for Native Mitral Valve Stenosis Using a Balloon-Expandable Prosthesis.
CONCLUSIONS: TMV implantation using the SAPIEN 3 aortic prosthesis in patients with heavy annular calcification is feasible and represents a reasonable bailout option for inoperable patients. However, several limitations need to be considered in this special patient population. PMID: 28760473 [PubMed - indexed for MEDLINE]
Source: The Annals of Thoracic Surgery - December 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Kiefer P, Noack T, Seeburger J, Hoyer A, Linke A, Mangner N, Lehmkuhl L, Mohr FW, Holzhey D Tags: Ann Thorac Surg Source Type: research

Transcatheter vs surgical aortic ‐valve replacement in low‐ to intermediate‐surgical‐risk candidates: A meta‐analysis and systematic review
The American and European expert documents recommend transcatheter aortic valve replacement (TAVR) for inoperable or high‐surgical‐risk patients with severe aortic stenosis. In comparison, efficacy of TAVR is relatively less studied in low‐ to intermediate‐surgical‐risk patients. We sought to discover whether TAVR can be as effective as surgical aortic valve replacement (SAVR) in low‐ to intermediate‐surgical‐risk candidates. Four randomized clinical trials (RCTs) and 8 prospective matched studies were selected using PubMed/MEDLINE, Embase, and Cochrane Library (inception: March 2017). Results were reported...
Source: Clinical Cardiology - November 23, 2017 Category: Cardiology Authors: Safi U. Khan, Ahmad N. Lone, Muhammad A. Saleem, Edo Kaluski Tags: REVIEW Source Type: research

Mitral valve pressure gradient after percutaneous mitral valve repair: every beat counts
Abstract A patient presented with symptoms of decompensated heart failure 2 months after percutaneous mitral valve (MV) repair. Echocardiography demonstrated impaired left ventricular function with elevated MV pressure gradients and pulmonary pressures during rapid atrial fibrillation. Heart rate control was achieved by implantation of a biventricular pacemaker with subsequent His‐bundle ablation because atrial fibrillation was refractory to medical treatment. During biventricular pacing at different rates (50–110 b.p.m.), heart rate correlated positively with both MV mean pressure gradient and global longitudinal st...
Source: ESC Heart Failure - November 23, 2017 Category: Cardiology Authors: Daniel Lavall, Bruno Scheller, Christian Werner, Axel Buob, Felix Mahfoud Tags: Case Report Source Type: research

Impact of active cancer disease on the outcome of patients undergoing transcatheter aortic valve replacement
ConclusionThe presence of ACD in patients undergoing TAVR is associated with significantly higher 1‐year mortality.
Source: Journal of Interventional Cardiology - November 22, 2017 Category: Cardiology Authors: Norman Mangner, Felix J. Woitek, Stephan Haussig, David Holzhey, Georg Stachel, Florian Schlotter, Robert H öllriegel, Friedrich W. Mohr, Gerhard Schuler, Axel Linke Tags: ORIGINAL INVESTIGATION Source Type: research

Efficacy and Efficiency of Perioperative Stellate Ganglion Blocks in Cardiac Surgery: A Pilot Study
Nationally, postoperative atrial fibrillation (POAF) occurs in up to 40% of patients after coronary artery bypass grafting (CABG), 50% of patients after valve surgery, 64% of patients after mitral valve and CABG, and 49% after aortic valve replacement.1 Atrial fibrillation worsens a patient ’s hemodynamic status and increases the risk of congestive heart failure, embolic events, and longer intensive care unit stays, leading to increased patient morbidity and strain on financial resources. In the United States, POAF carries a higher risk of stroke, worsened survival, and an additional 4.9 days and $10,000 to $11,500 in hospital stay costs.
Source: Journal of Cardiothoracic and Vascular Anesthesia - November 20, 2017 Category: Anesthesiology Authors: Christopher W. Connors, Wendy Y. Craig, Scott A. Buchanan, Justin M. Poltak, James B. Gagnon, Craig S. Curry Tags: Letter to the Editor Source Type: research

Assessment of Commonly Used Frailty Markers for High- and Extreme-Risk Patients Undergoing Transcatheter Aortic Valve Replacement
Conclusions Among high- and extreme-risk patients undergoing TAVR, our new frailty model was more discriminative of 30-day mortality than The Society of Thoracic Surgeons predicted risk of mortality. New cutoff values for frailty indicators were identified and will require further validation.
Source: The Annals of Thoracic Surgery - November 16, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Transapical Mitral Valve Implantation for Native Mitral Valve Stenosis Using a Balloon-Expandable Prosthesis
Conclusions TMV implantation using the SAPIEN 3 aortic prosthesis in patients with heavy annular calcification is feasible and represents a reasonable bailout option for inoperable patients. However, several limitations need to be considered in this special patient population.
Source: The Annals of Thoracic Surgery - November 16, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Long ‐term outcomes for different surgical strategies to treat left ventricular outflow tract obstruction in hypertrophic cardiomyopathy
ConclusionSeptal myectomy is a safe procedure resulting in symptomatic improvement in the majority of patients. The annual incidence of non‐fatal disease‐related complications after surgical treatment of LVOTO is relatively high. Patients who underwent MV replacements had poorer outcomes with less symptomatic benefit in spite of a similar reduction in LVOT gradients.
Source: European Journal of Heart Failure - November 16, 2017 Category: Cardiology Authors: Richard Collis, Oliver Watkinson, Constantinos O'Mahony, Oliver P. Guttmann, Antonis Pantazis, Maria Tome ‐Esteban, Victor Tsang, Venkatachalam Chandrasekaran, Christopher G.A. McGregor, Perry M. Elliott Tags: Research Article Source Type: research

Real-world experience using the ACURATE neo ™ prosthesis: 30-day outcomes of 1000 patients enrolled in the SAVI-TF registry.
CONCLUSIONS: In this initial experience, treatment with the ACURATE neoTM prosthesis resulted in excellent clinical outcomes with very low complication rates. PMID: 29131801 [PubMed - as supplied by publisher]
Source: EuroIntervention - November 15, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Clinical outcome and functional characteristics of patients with asymptomatic low-flow low-gradient severe aortic stenosis with preserved ejection fraction are closer to high-gradient severe than to moderate aortic stenosis
AbstractAsymptomatic “paradoxic” severe low-flow low-gradient aortic stenosis with preserved ejection fraction (PAS) constitutes a challenging condition where the optimal management and follow-up remain elusive. We evaluated the clinical outcome in patients with PAS as compared to asymptomatic patients with moderate (MAS) or classical severe aortic stenosis (CAS). Consecutive asymptomatic moderate or severe aortic stenosis patients without concomitant other heart or lung disease (n = 121) were invited. Participants (n = 74) were assigned to three subgroups with regard to degree of aortic stenosis: MAS (n = ...
Source: The International Journal of Cardiovascular Imaging - November 9, 2017 Category: Radiology Source Type: research

Medication Management of Patients Undergoing Transcatheter Aortic Valve Replacement
This article summarizes key literature supporting the pharmacologic management of patients receiving TAVR. This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 9, 2017 Category: Drugs & Pharmacology Authors: Bethany A. Kalich, J. Erin Ledford, Ian B. Hollis Tags: Review of Therapeutics Source Type: research

Medtronic wins CE Mark for Intellis SCS, PNS systems
Medtronic (NYSE:MDT) said today it won CE Mark approval in the European Union for its Intellis spinal cord stimulation and peripheral nerve stimulation systems designed to treat chronic pain. The Fridley, Minn.-based company touted the Intellis as the world’s smallest fully implantable SCS neurostim. The newly-cleared system includes improved battery performance and is managed through the use of a Samsung Galaxy Tab S2 tablet. “Medtronic’s goal is to simplify treatment and improve the patient experience with personalized therapy that provides long-term pain relief and helps restore function. The launch ...
Source: Mass Device - November 6, 2017 Category: Medical Devices Authors: Fink Densford Tags: Neuromodulation/Neurostimulation Pain Management Regulatory/Compliance Medtronic Source Type: news

TCT 2017: Medtronic touts results from 6-month Evolut Pro study
Medtronic (NYSE:MDT) today released six-month data from a study of its Evolut Pro transcatheter aortic valve replacement platform, touting low rates of paravalvular leaks and low rates of all-cause mortality and disabling stroke. Data came from 60 patients in the trial who received the Evolut Pro valve, and follow previously released 30-day outcomes. Results at six-months indicated trace or no paravalvular leaks in 88% of patients, with low rates of all-cause mortality and disabling stroke. No instances of coronary obstruction or valve thrombosis were reported and the permanent pacemaker implantation rate was 11.7%, Medt...
Source: Mass Device - November 2, 2017 Category: Medical Devices Authors: Fink Densford Tags: Catheters Clinical Trials Replacement Heart Valves Medtronic Source Type: news

Restrictive Mitral Valve Annuloplasty: Prognostic Implications of Left Ventricular Forward Flow.
CONCLUSIONS: In patients with severe secondary MR treated with surgical repair, LV forward flow was independently associated with better survival and lower risk of the combined endpoint. PMID: 28964411 [PubMed - indexed for MEDLINE]
Source: The Annals of Thoracic Surgery - November 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Kamperidis V, van Wijngaarden SE, van Rosendael PJ, Kong WK, Leung M, Sianos G, Ajmone Marsan N, Delgado V, Bax JJ Tags: Ann Thorac Surg Source Type: research

Dynamic changes in aortic impedance after transcatheter aortic valve replacement and its impact on exploratory outcome
AbstractValvulo-arterial impedance (Zva) has been shown to predict worse outcome in medically managed aortic stenosis (AS) patients. We aimed to investigate the association between Zva and left ventricular (LV) adaptation and to explore the predictive value of Zva for cardiac functional recovery and outcome after transcatheter aortic valve replacement (TAVR). We prospectively enrolled 128 patients with AS who underwent TAVR. Zva was calculated as: (systolic blood pressure  + mean transaortic gradient)/stroke volume index). Echocardiographic assessment occurred at baseline, 1-month and 1-year after TAVR. The primary end...
Source: The International Journal of Cardiovascular Imaging - November 1, 2017 Category: Radiology Source Type: research

Experimental Investigation of Left Ventricular Flow Patterns After Percutaneous Edge ‐to‐Edge Mitral Valve Repair
Abstract Mitral valve percutaneous edge‐to‐edge repair (PEtER) is a viable solution in high‐risk patients with severe symptomatic mitral regurgitation. However, the generated double‐orifice configuration poses challenges for the evaluation of the hemodynamic performance of the mitral valve and may alter flow patterns in the left ventricle (LV) during diastole. This in vitro study aims to evaluate the hemodynamic modifications following a simulated PEtER. A custom‐made mitral valve was developed, and two configurations were tested: (i) a single‐orifice valve with mitral regurgitation and (ii) a double‐orifice ...
Source: Artificial Organs - November 1, 2017 Category: Transplant Surgery Authors: Morteza Jeyhani, Shahrokh Shahriari, Michel Labrosse Tags: Main Text Source Type: research

TCT 2017: Medtronic touts 1-year intermediate data for Evolut R TAVR
Medtronic (NYSE:MDT) is touting data from a pair of studies of intermediate-risk patients implanted with its Evolut R replacement heart valve, presented today at the Transcatheter Cardiovascular Therapeutics annual meeting in Denver. Fridley, Minn.-based Medtronic presented results from its Surtavi trial and Evolut R Forward real-world study of its next-generation transcatheter aortic valve replacement today at TCT. One-year data from Surtavi, comparing the Evolut R and CoreValve devices with open heart surgery, showed a 7.8% mortality rate for the TAVR arm, compared with 8.5% for the open surgery arm. A sub-group analysi...
Source: Mass Device - October 31, 2017 Category: Medical Devices Authors: Brad Perriello Tags: Clinical Trials Replacement Heart Valves Medtronic Source Type: news

Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Chronic Kidney Disease
There are few data comparing outcomes of transcatheter aortic valve implantation (TAVI) vs. surgical aortic valve replacement (SAVR) in patients with chronic kidney disease (CKD). In this retrospective cohort study using the National Inpatient Sample 2011 – 2014, we included a total of 2820 TAVI and 4054 SAVR procedures, representative of 14,039 TAVI and 19,835 SAVR procedures nationally. Co-primary outcomes were in-hospital mortality, acute kidney injury (AKI), dialysis-requiring AKI, and post-operative stroke.
Source: The American Journal of Cardiology - October 31, 2017 Category: Cardiology Authors: Nilay Kumar, Rohan Khera, Neetika Garg, Justin B. Echouffo-Tcheugui, Anand Venkatraman, Ambarish Pandey, Deepak L. Bhatt Source Type: research

Hemodynamic assessment of Perceval sutureless bioprosthesis by dobutamine stress echocardiography
ConclusionsThe Perceval sutureless bioprosthesis demonstrated good hemodynamics at rest and under high workload. The significant increase in EOAi during DSE suggests the potential advantages of Perceval sutureless bioprostheses in case of small aortic annulus or when patient‐prosthesis mismatch is anticipated.
Source: Echocardiography - October 26, 2017 Category: Cardiology Authors: Antonino S. Rubino, Fausto Biancari, Vincenzo Caruso, Vincenzo Lavanco, Fiorella Privitera, Ivana Rinaldi, Maria Sanfilippo, Giovanni Millan, Lucia V. D'Urso, Sergio Castorina, Carmelo Mignosa Tags: ORIGINAL INVESTIGATION Source Type: research