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Therapy: Hormone Replacement Therapy

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Total 161 results found since Jan 2013.

Worsening Severity of Migraines in Current Users of Hormone Replacement Therapy Correlates to Increased Risk of Ischemic Stroke (I2.011)
Conclusions: Current HRT users that have an increase in severity of one grade or more of migraines are shown to have an increased risk of ischemic strokes.Disclosure: Dr. Rahman has nothing to disclose. Dr. Thomas has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Saeed has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rahman, H., Thomas, A., Malik, A., Saeed, O., Qureshi, A. Tags: Stroke in the Elderly and Young: Challenges for the Next Decade Poster Presentations Source Type: research

HRT review finds increased risk of blood clots and stroke
Conclusion This updated Cochrane review has found that oral HRT increases risk of stroke and blood clots, and does not appear to reduce overall risk of cardiovascular disease or death during follow-up. More exploratory analyses suggested that HRT might reduce risk of death from heart disease or non-fatal heart attack if it was started within 10 years of menopause, but this finding needs further confirmation. The review was carried out using robust methods and the trials were of good quality. Its findings are in line with the previous version of the review, and also with other reviews. There are some points to note: Thi...
Source: NHS News Feed - March 10, 2015 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

Stroke in Women
This article reviews sex differences in stroke risk and presentation, with a particular emphasis on the unique risk factors women experience throughout the lifespan. RECENT FINDINGS Although prior studies suggested women have worse outcomes after stroke, it is now clear that age, prestroke functional status, and comorbidities explain many of the differences between men and women in stroke severity, functional outcomes, and mortality. Several meta-analyses and large cohort studies have evaluated the risk factors for women related to reproductive factors and found that fewer years between menarche and menopause, pregnancy...
Source: CONTINUUM: Lifelong Learning in Neurology - April 1, 2020 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Contraceptive drug, Nestorone, enhances stem cell-mediated remodeling of the stroke brain by dampening inflammation and rescuing mitochondria
Free Radic Biol Med. 2022 Mar 24:S0891-5849(22)00123-X. doi: 10.1016/j.freeradbiomed.2022.03.020. Online ahead of print.ABSTRACTIschemic stroke remains a significant unmet need causing massive mortality and morbidity due to few treatment options with limited therapeutic window. The progestin Nestorone® (segesterone acetate) displays high affinity for the progesterone receptor in exerting its potent birth control and hormone replacement therapy. Accumulating evidence implicates a new utility of Nestorone in affording neuroprotection in a variety of central nervous system diseases, including stroke. However, the mechanism o...
Source: Free Radical Biology and Medicine - March 28, 2022 Category: Biology Authors: Jea-Young Lee Vanessa Castelli Narender Kumar Regine Sitruk-Ware Cesario V Borlongan Source Type: research

Previous Use of Unopposed Estrogen Hormone Replacement Therapy Continues to Cause Increased Risk for Future Ischemic Strokes (S4.008)
Conclusions:Previous use of unopposed estrogen HRT continues to increase risk for ischemic stroke after they are discontinued, although combination of estrogen and progesterone HRT do no continue to have a significantly increased risk. Future prospective studies are required to further investigate these correlations.Disclosure: Dr. Rahman has nothing to disclose. Dr. Thomas has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Saeed has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rahman, H., Thomas, A., Malik, A., Saeed, O., Qureshi, A. Tags: Health Disparities and Sex Differences in Stroke Source Type: research

Worsening Severity of Migraines in Current Users of Hormone Replacement Therapy Correlates to Increased Risk of Ischemic Stroke (P4.118)
Conclusions: Current HRT users that have an increase in severity of one grade or more of migraines are shown to have an increased risk of ischemic strokes.Disclosure: Dr. Rahman has nothing to disclose. Dr. Thomas has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Saeed has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rahman, H., Thomas, A., Malik, A., Saeed, O., Qureshi, A. Tags: Headache: Imaging and Other Source Type: research

Risk of stroke following antivenom use after venomous snakebite: correspondence
We read with great interest the epidemiological study by Hunget al.1 on the risk of stroke with antivenom use after venomous snakebite in Taiwan. According to the national medical claims data, the authors provide us with useful information and disclose that venomous snakebite is associated with an increased risk of hemorrhagic stroke after the use of antivenom after using the matching propensity score in relevant measurable covariates. We strongly agree with the comments by Yehet al.2 on the unmeasured confounders associated with stroke in the present study. Furthermore, we are concerned that other residual confounders rel...
Source: QJM - April 26, 2023 Category: Internal Medicine Source Type: research

The effect of growth hormone replacement in patients with hypopituitarism on pituitary tumor recurrence, secondary cancer, and stroke
AbstractGrowth hormone replacement therapy has benefits for patients with hypopituitarism. The safety profile in regard to tumor recurrence or progression, development of secondary malignancies, or cerebrovascular stroke is still an area of debate. A comprehensive search of multiple databases —MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus was conducted through August 2015. Eligible studies that evaluated long-term adverse events in adult patients with hypopituitarism treated with growth hormone replacement therapy a nd reported development of pituitar...
Source: Endocrine - November 3, 2016 Category: Endocrinology Source Type: research

Cryptogenic stroke in a young patient with heart disease and kidney failure.
CONCLUSIONS: Fabry's disease must be suspected in young males with heart disease, stroke or peripheral neuropathy, skin lesions, kidney failure and a history of cases in the family. Hormone replacement therapy must be established at an early stage, as it can improve the prognosis. PMID: 28497441 [PubMed - in process]
Source: Revista de Neurologia - May 13, 2017 Category: Neurology Authors: Oyanguren B, Segoviano R, Alegria E, Besada E, Gonzalez-Salaices M, Eimil-Ortiz M, Lopez de Silanes C Tags: Rev Neurol Source Type: research

A systematic review and meta-regression analysis to examine the ‘timing hypothesis’ of hormone replacement therapy on mortality, coronary heart disease, and stroke
ConclusionYounger initiation of HRT may be effective in reducing death and cardiac events. However, younger HRT initiators remained at an increased risk of stroke, TIA and systemic embolism and this risk increased as average age increased. Younger menopausal women using HRT to treat vasomotor symptoms do not appear to be at an increased risk of dying or experiencing CHD events.
Source: IJC Heart and Vasculature - January 18, 2019 Category: Cardiology Source Type: research

Hormone Replacement Therapy and Adverse Outcomes in Women With Atrial Fibrillation: An Analysis From the Atrial Fibrillation Follow-Up Investigation of Rhythm Management Trial Brief Reports
Conclusions— HRT does not independently predict mortality, thromboembolism, or bleeding in a large cohort of women with atrial fibrillation.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Apostolakis, S., Sullivan, R. M., Olshansky, B., Lip, G. Y. H. Tags: Other Treatment Brief Reports Source Type: research

Worsening Migraine During HRT Tied to Increased Stroke Risk Worsening Migraine During HRT Tied to Increased Stroke Risk
Women who have worsening migraines while receiving hormone replacement therapy are at increased risk for ischemic stroke, new research suggests. Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - February 18, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Study: Different hormone therapy formulations may pose different risks for heart attack and stroke
(Cedars-Sinai Medical Center) Post-menopausal women whose doctors prescribe hormone replacement therapy for severe hot flashes and other menopause symptoms may want to consider taking low doses of FDA-approved bioidentical forms of estrogen or getting their hormones via a transdermal patch. A new observational study shows bioidentical hormones in transdermal patches may be associated with a lower risk of heart attack and FDA-approved products -- not compounded hormones -- may be associated with a slightly lower risk of stroke compared to synthetic hormones in pill form.
Source: EurekAlert! - Medicine and Health - September 18, 2013 Category: Global & Universal Source Type: news

Different risks for heart attack and stroke posed by different hormone therapy formulations
Post-menopausal women whose doctors prescribe hormone replacement therapy for severe hot flashes and other menopause symptoms may want to consider taking low doses of Food and Drug Administration-approved bioidentical forms of estrogen or getting their hormones via a transdermal patch. A new observational study shows bioidentical hormones in transdermal patches may be associated with a lower risk of heart attack and FDA-approved products -- not compounded hormones -- may be associated with a slightly lower risk of stroke compared to synthetic hormones in pill form...
Source: Health News from Medical News Today - September 20, 2013 Category: Consumer Health News Tags: Menopause Source Type: news