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Total 221350 results found since Jan 2013.

Effects of Candesartan in Acute Stroke on Cognitive Function and Quality of Life: Results From the Scandinavian Candesartan Acute Stroke Trial Brief Reports
Conclusions— Candesartan did not improve cognitive function or quality of life. Rather, there were signs of harmful effects. These findings support the conclusion from our previous report that there is no indication for routine blood pressure–lowering treatment with candesartan in the acute phase of stroke. Clinical Trial Registration— URL: www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Hornslien, A. G., Sandset, E. C., Bath, P. M., Wyller, T. B., Berge, E., on Behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cardiovascular Pharmacology, Cerebrovascular disease/stroke, Acute Stroke Syndromes, Other Stroke Treatment - Medical Brief Reports Source Type: research

Urgent Carotid Surgery and Stenting May Be Safe After Systemic Thrombolysis for Stroke Clinical Sciences
Conclusions— Urgent carotid endarterectomy or carotid artery stenting after thrombolysis for stroke may be safe without increased risk of serious complications.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Koraen-Smith, L., Troeng, T., Bjorck, M., Kragsterman, B., Wahlgren, C.-M., on behalf of the Swedish Vascular Registry and the Riks-Stroke Collaboration, This work was supported by the Steering Committee of the Swedish Vascular Registry (Swedvasc):, Krags Tags: Acute Cerebral Infarction, Carotid Stenosis, Emergency treatment of Stroke, Carotid endarterectomy, Angioplasty and Stenting Clinical Sciences Source Type: research

Blood Pressure-Lowering Treatment With Candesartan in Patients With Acute Hemorrhagic Stroke Brief Reports
Conclusions— There was no evidence that blood pressure–lowering treatment with candesartan is beneficial during the first week of hemorrhagic stroke. Instead, there were signs that such treatment may be harmful, but this needs to be verified in larger studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Jusufovic, M., Sandset, E. C., Bath, P. M. W., Berge, E., on behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Brief Reports Source Type: research

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis? Clinical Sciences
Conclusions— In children with dissection and transient cerebral arteriopathy, cerebral arteries demonstrate increased tortuosity. Quantified arterial tortuosity may represent a clinically relevant imaging biomarker of vascular biology in pediatric stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Wei, F., Diedrich, K. T., Fullerton, H. J., deVeber, G., Wintermark, M., Hodge, J., Kirton, A., the Vascular Effects of Infection in Pediatric Stroke (VIPS) Investigators, Dowling, Benedict, Bernard, Fox, Friedman, Lo, Ichord, Tan, Mackay, Hernandez, Hump Tags: Risk Factors, Angiography, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Vascular Disease Clinical Sciences Source Type: research

Characteristics and Outcomes of Very Elderly Enrolled in a Prehospital Stroke Research Study Clinical Sciences
Conclusions— Inclusion of the very elderly population in acute stroke clinical trials would both significantly increase study participation and generalizability of future acute stroke clinical trials. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00059332.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Sanossian, N., Apibunyopas, K. C., Liebeskind, D. S., Starkman, S., Burgos, A. M., Conwit, R., Eckstein, M., Pratt, F., Stratton, S., Hamilton, S., Saver, J. L., FAST-MAG (Field Administration of Stroke Therapy-Magnesium) Investigators and Coordinators Tags: Cerebrovascular Disease/Stroke, Neuroprotectants Clinical Sciences Source Type: research

Very Low Quality of Life After Acute Stroke: Data From the Efficacy of Nitric Oxide in Stroke Trial Clinical Sciences
Conclusions— Very low health-related quality of life is relatively common after stroke, particularly in patients with mobility problems or who are dependent on help for usual activities, and is related to poor functional outcome measures. Clinical Trial Registration— URL: http://www.controlled-trials.com/. Unique identifier: ISRCTN99414122.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Sprigg, N., Selby, J., Fox, L., Berge, E., Whynes, D., Bath, P. M. W., for the Efficacy of Nitric Oxide in Stroke Investigators Tags: Other Stroke Clinical Sciences Source Type: research

Implementing a Simple Care Bundle Is Associated With Improved Outcomes in a National Cohort of Patients With Ischemic Stroke Clinical Sciences
Conclusions— Achieving a care bundle for ischemic stroke is associated with reduced mortality at 30 days and 6 months and increased likelihood of discharge to usual residence at 6 months.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Turner, M., Barber, M., Dodds, H., Murphy, D., Dennis, M., Langhorne, P., Macleod, M.-J., on behalf of the Scottish Stroke Care Audit Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Bigger, Faster?: Associations Between Hospital Thrombolysis Volume and Speed of Thrombolysis Administration in Acute Ischemic Stroke Clinical Sciences
Conclusions— Hospitals with higher volumes of thrombolysis activity achieve statistically and clinically significant shorter delays in administering tPA to patients after arrival in hospital.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Bray, B. D., Campbell, J., Cloud, G. C., Hoffman, A., Tyrrell, P. J., Wolfe, C. D. A., Rudd, A. G., on behalf of the Intercollegiate Stroke Working Party Group Tags: Health policy and outcome research, Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Effect of Collateral Blood Flow on Patients Undergoing Endovascular Therapy for Acute Ischemic Stroke Clinical Sciences
Conclusions— Collaterals correlate with baseline National Institutes of Health Stroke Scale, perfusion-weighted imaging volume, and good reperfusion. However, target mismatch patients who reperfuse seem to have favorable outcomes at a similar rate, irrespective of the collateral score. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01349946.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Marks, M. P., Lansberg, M. G., Mlynash, M., Olivot, J.-M., Straka, M., Kemp, S., McTaggart, R., Inoue, M., Zaharchuk, G., Bammer, R., Albers, G. W., for Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2 (DEFUSE 2) Investigato Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Angiography, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Enrollment Yield and Reasons for Screen Failure in a Large Prehospital Stroke Trial Brief Reports
Conclusions— In this large, multicenter prehospital trial, nearly 40% of every calls from the field to physician-investigators resulted in trial enrollments. The most common reasons for nonenrollment were out of window last known well time, prestroke confounding medical condition, and absence of a consent provider. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00059332.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Kim, D.-H., Saver, J. L., Starkman, S., Liebeskind, D. S., Ali, L. K., Restrepo, L., Kim-Tenser, M., Valdes-Sueiras, M., Eckstein, M., Pratt, F., Stratton, S., Hamilton, S., Conwit, R., Sanossian, N., on behalf of the Field Administration of Stroke Therap Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke, Neuroprotectants Brief Reports Source Type: research

Differential Effect of Baseline Computed Tomographic Angiography Collaterals on Clinical Outcome in Patients Enrolled in the Interventional Management of Stroke III Trial Clinical Sciences
Conclusion— Using data from a large randomized controlled trial (IMS III), we show that baseline computed tomographic angiography collaterals are a robust determinant of final clinical outcome and could be used to select patients for endovascular therapy. Clinical Trial Registration— URL: http://www.clinicaltrials.gov/ct2/show/. Unique identifier: 0020NCT00359424.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Menon, B. K., Qazi, E., Nambiar, V., Foster, L. D., Yeatts, S. D., Liebeskind, D., Jovin, T. G., Goyal, M., Hill, M. D., Tomsick, T. A., Broderick, J. P., Demchuk, A. M., for the Interventional Management of Stroke III Investigators Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Burden and Outcome of Prevalent Ischemic Brain Disease in a National Acute Stroke Registry Clinical Sciences
Conclusions— In our national cohort of patients with acute ischemic stroke, nearly two thirds had a prior overt stroke or subclinical stroke. Risk of poor functional outcomes was increased for patients with prior stroke, both overt and subclinical.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Koton, S., Tsabari, R., Molshazki, N., Kushnir, M., Shaien, R., Eilam, A., Tanne, D., on behalf of the NASIS Investigators Tags: Acute Cerebral Infarction, Primary and Secondary Stroke Prevention, Risk Factors for Stroke Clinical Sciences Source Type: research

Stroke Awareness Among Inpatient Nursing Staff at an Academic Medical Center Brief Reports
Conclusions— Stroke outcome expectations and self-efficacy are associated with stroke knowledge and should be included in nursing education about stroke.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Adelman, E. E., Meurer, W. J., Nance, D. K., Kocan, M. J., Maddox, K. E., Morgenstern, L. B., Skolarus, L. E. Tags: Cerebrovascular disease/stroke, Behavioral Changes and Stroke Brief Reports Source Type: research

Family History in Young Patients With Stroke Brief Reports
Conclusions— Although present in about a third of patients, a family history of stroke is not specifically related to stroke pathogenic subtypes in patients with young stroke. Young women with stroke more often report stroke in the maternal lineage. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Thijs, V., Grittner, U., Dichgans, M., Enzinger, C., Fazekas, F., Giese, A.-K., Kessler, C., Kolodny, E., Kropp, P., Martus, P., Norrving, B., Ringelstein, E. B., Rothwell, P. M., Schmidt, R., Tanislav, C., Tatlisumak, T., von Sarnowski, B., Rolfs, A., on Tags: Clinical genetics, Acute Cerebral Infarction, Embolic stroke, Genetics of Stroke Brief Reports Source Type: research

Family History and Risk of Recurrent Stroke Clinical Sciences
Conclusions— This study suggests that elevated risks of recurrent stroke are associated with having relatives with early-onset stroke and siblings with stroke histories, implying that additional precautions may be needed in such populations.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Chung, J.-W., Kim, B. J., Han, M.-K., Kang, K., Park, J.-M., Park, S.-S., Park, T. H., Cho, Y.-J., Hong, K.-S., Lee, K. B., Kim, J. G., Ko, Y., Lee, S., Nah, H.-W., Kim, D.-H., Cha, J.-K., Oh, M.-S., Yu, K.-H., Lee, B.-C., Jang, M. S., Lee, J. S., Lee, J. Tags: Genetics, Quality and Outcomes, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research