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Total 49 results found since Jan 2013.
Discovery could lead to better recovery after stroke
UCLA researchers have identified a molecule that, after a stroke, signals brain tissue to form new connections to compensate for the damage and initiate repairs to the brain.
The finding could eventually lead to a new treatment to promote brain repair and functional recovery in people who have suffered a stroke, which is the leading cause of serious long-term disability in adults.
The five-year study, performed in an animal model, was the first to identify growth differentiation factor 10, or GDF10, a molecule that previously had no known role in the adult brain, said Dr. S. Thomas Carmichael, the study’s senior author ...
Source: UCLA Newsroom: Health Sciences - October 26, 2015 Category: Universities & Medical Training Source Type: news
UCLA, partners get $11M to develop stroke-prevention programs for minority populations
UCLA researchers and their partners across Los Angeles County have been awarded an $11 million federal grant to fund research on community-based interventions aimed at reducing the higher rates of stroke and death from stroke among disadvantaged Hispanics, African Americans and Asian Americans.
Research has shown that stroke risk can be substantially lowered by increasing physical activity, controlling blood pressure, adopting a healthy diet, quitting smoking, lowering cholesterol and, for certain individuals, taking medication like aspirin.
However, the underserved populations targeted by this research progr...
Source: UCLA Newsroom: Health Sciences - May 1, 2013 Category: Universities & Medical Training Source Type: news
Clinical Evaluation of the Patient With Acute Stroke
This article reviews the clinical evaluation of the patient with acute stroke, including key questions in the focused stroke history, important aspects of the National Institutes of Health Stroke Scale and focused neurologic examination, and the significance of the basic head CT scan in informing a timely treatment decision.
Recent Findings: Advances in both stroke treatment and enhanced diagnostics support an evolving paradigm for acute stroke care, ranging from the prehospital setting to the rehabilitative setting. An international emphasis on best practice strategies promotes efficiency and standardization in stroke sy...
Source: CONTINUUM: Lifelong Learning in Neurology - February 1, 2017 Category: Neurology Tags: Review Articles Source Type: research
Prediction of blood pressure variability during thrombectomy using supervised machine learning and outcomes of patients with ischemic stroke from large vessel occlusion
AbstractMechanical thrombectomy (MT) is the standard of care for patients with acute ischemic stroke from large vessel occlusion (AIS-LVO). The association of blood pressure variability (BPV) during MT and outcomes are unknown. We leveraged a supervised machine learning algorithm to predict patient characteristics that are associated with BPV indices. We performed a retrospective review of our comprehensive stroke center ’s registry of all adult patients undergoing MT between 01/01/2016 and 12/31/2019. The primary outcome was poor functional independence, defined as 90-day modified Rankin Scale (mRS) ≥ 3. We used p...
Source: Journal of Thrombosis and Thrombolysis - April 12, 2023 Category: Hematology Source Type: research
Assessing stroke severity using electronic health record data: a machine learning approach
Stroke severity is an important predictor of patient outcomes and is commonly measured with the National Institutes of Health Stroke Scale (NIHSS) scores. Because these scores are often recorded as free text i...
Source: BMC Medical Informatics and Decision Making - January 8, 2020 Category: Information Technology Authors: Emily Kogan, Kathryn Twyman, Jesse Heap, Dejan Milentijevic, Jennifer H. Lin and Mark Alberts Tags: Research article Source Type: research
Large Vessel Occlusion Prediction in the Emergency Department with National Institutes of Health Stroke Scale Components: A Machine Learning Approach
To determine the feasibility of using a machine learning algorithm to screen for large vessel occlusions (LVO) in the Emergency Department (ED).
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2021 Category: Neurology Authors: Donglai Huo, Michelle Leppert, Rebecca Pollard, Sharon N. Poisson, Xiang Fang, David Rubinstein, Igor Malenky, Kelsey Eklund, Eric Nyberg Tags: Short Communication Source Type: research
Between Extremes: Health Effects of Heat and Cold
Nate Seltenrich covers science and the environment from Petaluma, CA. His work has appeared in High Country News, Sierra, Yale Environment 360, Earth Island Journal, and other regional and national publications.
Background image: © Roy Scott
About This Article open
Citation: Seltenrich N. 2015. Between extremes: health effects of heat and cold. Environ Health Perspect 123:A275–A279; http://dx.doi.org/10.1289/ehp.123-A275
Published: 1 November 2015
PDF Version (2.4 MB)
Although heat waves and cold snaps pose major health risks and grab headlines when they occur, recent studies have uncovered a more complex and...
Source: EHP Research - November 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News November 2015 Source Type: research
Brain rewires itself after damage or injury, life scientists discover
When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the regions of the brain involved in creating those alternate pathways — often far from the damaged site.
The research, conducted by UCLA's Michael Fanselow and Moriel Zelikowsky in collaboration with Bryce Vissel, a group leader of the neuroscience research program at Sydney's Garvan Institute of Medical Research, appears this week in the early online edition of the journal Proceedings of the National Academy of Sciences.
...
Source: UCLA Newsroom: Health Sciences - May 15, 2013 Category: Universities & Medical Training Source Type: news
Death by a Thousand Cuts
It is likely that you don't realize what your state and our nation have lost in economic terms and research productivity as a result of recent cuts in the federal budget and budget instability brought on by a failure of Congress to pass a budget in a timely manner. Although some members of Congress strongly support increased funding for U.S. research, others argue that the time has come for the cost of basic biomedical research to be borne by industry and philanthropy. Those who make that argument either ignore, or are unaware, that this experiment has already been tried -- unsuccessfully.
Nearly 80 years ago, Louisiana ...
Source: Science - The Huffington Post - October 24, 2014 Category: Science Source Type: news
Prevention of central nervous system sequelae in sickle cell disease without evidence from randomized controlled trials: the case for a team-based learning collaborative.
Authors: DeBaun MR, King AA
Abstract
Since 1998, the National Institutes of Health has funded 5 randomized controlled trials (RCTs) for primary and secondary prevention of strokes in children with sickle cell anemia (SCA). In a systematic fashion, these trials have significantly advanced the care of children with SCA. In the absence of an RCT, clinicians are often compelled to make decisions at the bedside, based on experience, observational studies, and principles of hematology. We will provide an initial example that describes how a team-based, learning collaborative developed a multisite standard care protocol w...
Source: Hematology ASH Education Program - December 4, 2016 Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research
Development and validation of Risk Equations for Complications Of type 2 Diabetes (RECODe) using individual participant data from randomised trials
Publication date: Available online 10 August 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Sanjay Basu, Jeremy B Sussman, Seth A Berkowitz, Rodney A Hayward, John S Yudkin Background In view of substantial mis-estimation of risks of diabetes complications using existing equations, we sought to develop updated Risk Equations for Complications Of type 2 Diabetes (RECODe). Methods To develop and validate these risk equations, we used data from the Action to Control Cardiovascular Risk in Diabetes study (ACCORD, n=9635; 2001–09) and validated the equations for microvascular events using data from the Di...
Source: The Lancet Diabetes and Endocrinology - August 11, 2017 Category: Endocrinology Source Type: research
Cochrane author ’s work acknowledged in NIHR co-production publication
Cochrane author, and joint Co-ordinating editor, Alex Pollock, of Glasgow Caledonian University has seen her ground-breaking work in co-producing a Cochrane review included in a new UK ’s National Institute of Health Research (NIHR) INVOLVE publication.Alex involved stroke survivors, carers, physiotherapists and educators in an update of a Cochrane systematic review relating to physiotherapy after stroke. Her innovative work was included inCo-production in Action Number Two, as an example of good practice in Co-production, published in November 2019 by INVOLVE. You can hear Alex talk about her work in a webinar recorded ...
Source: Cochrane News and Events - December 3, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news
How AI Is Changing Medical Imaging to Improve Patient Care
That doctors can peer into the human body without making a single incision once seemed like a miraculous concept. But medical imaging in radiology has come a long way, and the latest artificial intelligence (AI)-driven techniques are going much further: exploiting the massive computing abilities of AI and machine learning to mine body scans for differences that even the human eye can miss.
Imaging in medicine now involves sophisticated ways of analyzing every data point to distinguish disease from health and signal from noise. If the first few decades of radiology were about refining the resolution of the pictures taken of...
Source: TIME: Health - November 4, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Frontiers of Medicine 2022 healthscienceclimate Innovation sponsorshipblock Source Type: news
NIH launches collaborative effort to find biomarkers for Parkinson's
(NIH/National Institute of Neurological Disorders and Stroke) The National Institutes of Health has launched a new initiative to help researchers investigate biomarkers for Parkinson's disease, and to help patients learn about and participate in such studies. So far, the NINDS Parkinson's Disease Biomarkers Program has funded nine research teams taking a variety of unique approaches to discover new biomarkers. To support collaboration across these projects and others, the PDBP is introducing a new online platform for investigators to share their data.
Source: EurekAlert! - Medicine and Health - January 15, 2013 Category: Global & Universal Source Type: news
If you could propose one idea to help improve health care delivery in the United States, what would it be?
Thumbnail: Tags: conversationsphrma conversationslarry hausnermyrl weinbergchris hansennancy brownContributors: 11621161115911631173Contributions: Read Larry Hausner's bio
Despite the rapid development of innovative technologies in the health care field, we have yet to discover a panacea that will easily transform our health care system into one that provides high-quality and cost-effective care. What we have discovered and come to agree on over the last decade is that our sick care system must be reconfigured to a health care system that emphasizes wellness and prevention. For that reason, I offer ...
Source: PHRMA - June 24, 2013 Category: Pharmaceuticals Authors: rlowe Source Type: news
