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Untargeted metabolomics predicts the functional outcome of ischemic stroke.
CONCLUSION: Metabolomics is a potential method to explore the blood biomarkers of acute ischemic stroke. The patients with unfavorable outcomes had a lower PAF level compared to those with favorable outcomes. PMID: 32414667 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - May 12, 2020 Category: General Medicine Authors: Chi NF, Chang TH, Lee CY, Wu YW, Shen TA, Chan L, Chen YR, Chiou HY, Hsu CY, Hu CJ Tags: J Formos Med Assoc Source Type: research

Imaging-based outcome prediction in posterior circulation stroke
ConclusionMachine learning-based evaluation of pc-ASPECTS regions predicts functional outcome of pc-stroke patients with higher accuracy than conventional assessments. This could optimize triage for additional diagnostics and allocation of best possible medical care and might allow required arrangements of the social environment at an early point of time.
Source: Journal of Neurology - March 7, 2022 Category: Neurology Source Type: research

Prediction of blood pressure variability during thrombectomy using supervised machine learning and outcomes of patients with ischemic stroke from large vessel occlusion
AbstractMechanical thrombectomy (MT) is the standard of care for patients with acute ischemic stroke from large vessel occlusion (AIS-LVO). The association of blood pressure variability (BPV) during MT and outcomes are unknown. We leveraged a supervised machine learning algorithm to predict patient characteristics that are associated with BPV indices. We performed a retrospective review of our comprehensive stroke center ’s registry of all adult patients undergoing MT between 01/01/2016 and 12/31/2019. The primary outcome was poor functional independence, defined as 90-day modified Rankin Scale (mRS) ≥ 3. We used p...
Source: Journal of Thrombosis and Thrombolysis - April 12, 2023 Category: Hematology Source Type: research

Machine learning volumetry of ischemic brain lesions on CT after thrombectomy —prospective diagnostic accuracy study in ischemic stroke patients
ConclusionNCCT ILV measured automatically by the Brainomix software might be considered a valuable radiological outcome measure.
Source: Neuroradiology - April 21, 2020 Category: Radiology Source Type: research

Multivariate prediction of functional outcome using lesion topography characterized by acute diffusion tensor imaging
Publication date: Available online 10 April 2019Source: NeuroImage: ClinicalAuthor(s): Eric Moulton, Romain Valabregue, Stephane Lehéricy, Yves Samson, Charlotte RossoAbstractThe relationship between stroke topography and functional outcome has largely been studied with binary manual lesion segmentations. However, stroke topography may be better characterized by continuous variables capable of reflecting the severity of ischemia, which may be more pertinent for long-term outcome. Diffusion Tensor Imaging (DTI) constitutes a powerful means of quantifying the degree of acute ischemia and its potential relation to functional...
Source: NeuroImage: Clinical - April 11, 2019 Category: Radiology Source Type: research