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Total 44 results found since Jan 2013.
Discovery could lead to better recovery after stroke
UCLA researchers have identified a molecule that, after a stroke, signals brain tissue to form new connections to compensate for the damage and initiate repairs to the brain.
The finding could eventually lead to a new treatment to promote brain repair and functional recovery in people who have suffered a stroke, which is the leading cause of serious long-term disability in adults.
The five-year study, performed in an animal model, was the first to identify growth differentiation factor 10, or GDF10, a molecule that previously had no known role in the adult brain, said Dr. S. Thomas Carmichael, the study’s senior author ...
Source: UCLA Newsroom: Health Sciences - October 26, 2015 Category: Universities & Medical Training Source Type: news
UCLA Health launches pioneering mobile stroke unit with support from L.A. County
Roughly every 40 seconds, someone in the United States will have a stroke. Almost every four minutes, one of those people will die as a result. Against that backdrop, UCLA Health has officially launched the first mobile stroke unit on the West Coast, enabling rapid delivery of brain-saving medications to stroke patients who might otherwise face debilitating delays in treatment. As part of the first phase of a pilot program, the specialized ambulance unit and highly trained personnel began responding in September to select 911 calls in Santa Monica in coordination with the Santa Monica Fire Department. With support from t...
Source: UCLA Newsroom: Health Sciences - October 26, 2017 Category: Universities & Medical Training Source Type: news
UCLA, partners get $11M to develop stroke-prevention programs for minority populations
UCLA researchers and their partners across Los Angeles County have been awarded an $11 million federal grant to fund research on community-based interventions aimed at reducing the higher rates of stroke and death from stroke among disadvantaged Hispanics, African Americans and Asian Americans.
Research has shown that stroke risk can be substantially lowered by increasing physical activity, controlling blood pressure, adopting a healthy diet, quitting smoking, lowering cholesterol and, for certain individuals, taking medication like aspirin.
However, the underserved populations targeted by this research progr...
Source: UCLA Newsroom: Health Sciences - May 1, 2013 Category: Universities & Medical Training Source Type: news
Device used to close small hole in heart may protect against recurrent stroke
A device used to close a small hole in the heart may benefit certain stroke patients by providing an extra layer of protection for those facing years of ongoing stroke risk, according to the results of a large clinical trial led by UCLA researchers.“It is a major new treatment option for some people,” said Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center and lead author of the study. However, he added, “Using the device is going to have to be a considered clinical decision between the doctor and the patient about who’s the right person to get it.”Thefindings appear in the Sept. 14 New England Jo...
Source: UCLA Newsroom: Health Sciences - September 14, 2017 Category: Universities & Medical Training Source Type: news
A missing gene makes a big difference in patients ’ recovery from mild stroke
More than 6 million Americans live with disabilities following a stroke. Even mild strokes can leave survivors with arm and leg weakness, poor muscle control and memory lapses that worsen with age. Now UCLA neuroscientists have found that patients born without a gene called CCR5 recover better from mild stroke than patients with the gene. The team partnered with Israeli researchers to study the missing gene ’s effect on brain function.Published Feb. 21 in the journal Cell, the findings could lead to the first pill to reverse the physical and mental aftermath of mild stroke.“This is the first time that a human gene h...
Source: UCLA Newsroom: Health Sciences - February 21, 2019 Category: Universities & Medical Training Source Type: news
Know the signs of heat stroke and exhaustion
Heat can be deadly.As summer temperatures climb — and as climate change contributes to more 100-degree days each year — heat illnesses become a more serious risk, particularly for young children, older adults, outdoor workers, athletes and people with chronic conditions.“On any day with extreme heat, emergency rooms in Los Angeles see an additional 1,500 patients,” said Dr. David Eisenman, a professor at the UCLA Fielding School of Public Health and co-leader of aresearch project to address extreme heat in Los Angeles.“We estimate that an additional 16 people die on a single day of heat in Los Angeles County,...
Source: UCLA Newsroom: Health Sciences - June 23, 2022 Category: Universities & Medical Training Source Type: news
A step toward understanding why COVID-19 boosts stroke risk
A UCLA-led study may help explain how COVID-19 increases the risk for stroke. Scientists made the finding by running fluid spiked with a COVID-19–like protein through a 3D-printed model of the arteries of a patient who had suffered a stroke. Although COVID-19 was first identified by its severe respiratory symptoms, the virus has caused strokes in young people who had no known risk factors. But little is known about how the virus increases the risk for stroke.To learn more, UCLA researchers used a 3D-printed silicone model of blood vessels in the brain to mimic the forces generated by blood pushing through an artery th...
Source: UCLA Newsroom: Health Sciences - December 18, 2020 Category: Universities & Medical Training Source Type: news
Thomas Carmichael elected to the Association of American Physicians
Dr. S. Thomas Carmichael has been elected to the Association of American Physicians, an honor society recognizing exemplary physician-scientists who contribute to clinical medicine through the pursuit of basic science. The newly elected members for 2021 were recognized at the association ’s annual meeting, which was held virtually April 8–10.Carmichael, UCLA ’s Frances Stark Professor of Neurology, is the chair of theneurology department in the David Geffen School of Medicine at UCLA and co-director of theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.In his research, Carmichael s...
Source: UCLA Newsroom: Health Sciences - April 9, 2021 Category: Universities & Medical Training Source Type: news
Thomas Carmichael elected to Association of American Physicians
Dr. S. Thomas Carmichael has been elected to the Association of American Physicians, an honor society recognizing exemplary physician-scientists who contribute to clinical medicine through the pursuit of basic science. The newly elected members for 2021 were recognized at the association ’s annual meeting, which was held virtually April 8–10.Carmichael, UCLA ’s Frances Stark Professor of Neurology, is the chair of theneurology department in the David Geffen School of Medicine at UCLA and co-director of theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.In his research, Carmichael s...
Source: UCLA Newsroom: Health Sciences - April 9, 2021 Category: Universities & Medical Training Source Type: news
Brain rewires itself after damage or injury, life scientists discover
When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the regions of the brain involved in creating those alternate pathways — often far from the damaged site.
The research, conducted by UCLA's Michael Fanselow and Moriel Zelikowsky in collaboration with Bryce Vissel, a group leader of the neuroscience research program at Sydney's Garvan Institute of Medical Research, appears this week in the early online edition of the journal Proceedings of the National Academy of Sciences.
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Source: UCLA Newsroom: Health Sciences - May 15, 2013 Category: Universities & Medical Training Source Type: news
Under Affordable Care Act, Americans have had more preventive care for heart health, UCLA study finds
By reducing out-of-pocket costs for preventive treatment, the Affordable Care Act appears to have encouraged more people to have health screenings related to their cardiovascular health,a UCLA study found. Comparing figures from 2006 through 2013, researchers found that more people were screened for diabetes, high cholesterol, cigarette use and high blood pressure — all risk factors for heart disease — after the ACA was implemented than before.But the research, published in the peer-reviewed American Journal of Managed Care, also revealed a disparity between men and women in one key area. Although more men who are at r...
Source: UCLA Newsroom: Health Sciences - November 23, 2017 Category: Universities & Medical Training Source Type: news
Sleep biology discovery could lead to new insomnia treatments that don ’t target the brain
UCLA scientists report the first evidence that a gene outside the brain controls the ability to rebound from sleep deprivation — a surprising discovery that could eventually lead to greatly improved treatments for insomnia and other sleep disorders that do not involve getting a drug into the brain.The scientists report that increasing the level of Bmal1 — a critical master gene that regulates sleep patterns — in skeletal muscle makes mice resistant to sleep deprivation.“When we first saw the importance of the muscle, we were surprised,” said senior author Ketema Paul, UCLA associate professor of integrative biolo...
Source: UCLA Newsroom: Health Sciences - August 10, 2017 Category: Universities & Medical Training Source Type: news
Spacing out after staying up late? Here ’s why
Ever sleep poorly and then walk out of the house without your keys? Or space out while driving to work and nearly hit a stalled car?A new study led by UCLA ’sDr. Itzhak Fried is the first to reveal how sleep deprivation disrupts brain cells ’ ability to communicate with each other. Fried and his colleagues believe that disruption leads to temporary mental lapses that affect memory and visual perception. Their findings are published online today by Nature Medicine.“We discovered that starving the body of sleep also robs neurons of the ability to function properly,” said Fried, the study’s senior author, a profess...
Source: UCLA Newsroom: Health Sciences - November 6, 2017 Category: Universities & Medical Training Source Type: news
UCLA researchers study genetics ’ role in COVID-19 susceptibility, severity
“One of the most troubling things about COVID-19 is that we have a limited ability to predict how sick a specific individual will get,” said Dr. Daniel Geschwind.Geschwind is the MacDonald Distinguished Professor in Human Genetics at theDavid Geffen School of Medicine at UCLA and a member of theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. And he ’s part of a team of UCLA scientists conducting research to learn why certain people get sick from the virus that causes COVID-19 — and why others don’t.Millions of people around the world have been infected with SARS-CoV-2, the v...
Source: UCLA Newsroom: Health Sciences - October 26, 2020 Category: Universities & Medical Training Source Type: news
Scientists jump-start two people ’s brains after coma
In 2016, a team led by UCLA ’s Martin Monti reported that a 25-year-old man recovering from a coma had made remarkable progress following a treatment to jump-start his brain using ultrasound.Wired U.K. called the news one of the best things that happened in 2016. At the time, Monti acknowledged that although he was encouraged by the outcome, it was possible the scientists had gotten a little lucky.Now, Monti and colleagues report that two more patients with severe brain injuries — both had been in what scientists call a long-term “minimally conscious state” — have made impressive progress thanks to the same te...
Source: UCLA Newsroom: Health Sciences - January 27, 2021 Category: Universities & Medical Training Source Type: news
