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Impact of 5‐Hz rTMS over the primary sensory cortex is related to white matter volume in individuals with chronic stroke
We examined the relationship between rTMS response, indexed by motor learning and cortical morphology in individuals with stroke. Sensory cortical white matter volume was associated with behavioural response to 5 Hz rTMS over ipsilesional sensory cortex followed by motor practice. Understanding factors contributing to variability of response to rTMS may help clarify both who may benefit from rTMS, and also which cortical areas may be most susceptible to rTMS‐induced neuroplastic change.
Source: European Journal of Neuroscience - September 1, 2014 Category: Neuroscience Authors: Sonia M. Brodie, Michael R. Borich, Lara A. Boyd Tags: Research Report Source Type: research

In vitro and in  vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury
Abstract PSD‐95 inhibitors have been shown to be neuroprotective in stroke, but have only to a very limited extent been evaluated in the treatment of traumatic brain injury (TBI) that has pathophysiological mechanisms in common with stroke. The aims of the current study were to assess the effects of a novel dimeric inhibitor of PSD‐95, UCCB01‐147, on histopathology and long‐term cognitive outcome after controlled cortical impact (CCI) in rats. As excitotoxic cell death is thought to be a prominent part of the pathophysiology of TBI, we also investigated the neuroprotective effects of UCCB01‐147 and related compou...
Source: European Journal of Neuroscience - December 3, 2016 Category: Neuroscience Authors: Jens Bak Sommer, Anders Bach, Hana Mal á, Kristian Strømgaard, Jesper Mogensen, Darryl S. Pickering Tags: Research Report Source Type: research

In vitro and in vivo effects of a novel dimeric inhibitor of PSD ‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury
This article is protected by copyright. All rights reserved.
Source: European Journal of Neuroscience - November 16, 2016 Category: Neuroscience Authors: Jens Bak Sommer, Anders Bach, Hana Mal á, Kristian Strømgaard, Jesper Mogensen, Darryl Scott Pickering Tags: Research Report Source Type: research

Action observation with kinesthetic illusion can produce human motor plasticity
This article is protected by copyright. All rights reserved.
Source: European Journal of Neuroscience - April 17, 2015 Category: Neuroscience Authors: Ippei Nojima, Satoko Koganemaru, Toshio Kawamata, Hidenao Fukuyama, Tatsuya Mima Tags: Research Report Source Type: research