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An interpretable machine learning-based prediction model for risk of death for patients with ischemic stroke in intensive care unit
CONCLUSION: This EBM model has a good performance for predicting the risk of death within one year in patients with severe ischemic stroke and allows clinicians to better understand the contributing factors of the patients' outcomes through the model interpretability.PMID:37488807 | PMC:PMC10366517 | DOI:10.12122/j.issn.1673-4254.2023.07.21
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: X Luo Y Cheng C Wu J He Source Type: research

Next-Generation Models for Predicting Winning Times in Elite Swimming Events: Updated Predictions for the Paris 2024 Olympic Games
CONCLUSIONS: These models, and associated predictions for swimming events at the Paris 2024 Olympic Games, provide an evidence-based performance framework for coaches, sport-science support staff, and athletes to develop and evaluate training plans, strategies, and tactics, as well as informing resource allocation to athletes, based on their potential for the Paris 2024 Olympic Games.PMID:37487585 | DOI:10.1123/ijspp.2023-0174
Source: International Journal of Sports Physiology and Performance - July 24, 2023 Category: Sports Medicine Authors: I ñigo Mujika David B Pyne Paul Pao-Yen Wu Kwok Ng Emmet Crowley Cormac Powell Source Type: research

Can Patent Foramen Ovales Cause Problems?
Discussion During fetal development, the heart primum and secundum septa grow and overlap leaving a small but important channel between the two atria. The foramen ovale is a flap valve moving blood from the right atrium into the left atrium directly and bypassing the high pressure pulmonary system. After birth and breathing air, the neonate’s lungs open up and the pulmonary vascular resistance decreases. The left atrium now has a relatively higher pressure than the right atria, and therefore pressure on the flap valve closes the foramen ovale. Usually within 6-12 months, the fusion of the primum and secundum of the f...
Source: PediatricEducation.org - July 24, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Deep-Learning-Enabled Microwave-Induced Thermoacoustic Tomography Based on ResAttU-Net for Transcranial Brain Hemorrhage Detection
Conclusion: The proposed ResAttU-Net-based DL-MITAT method is promising for mitigating the acoustic inhomogeneity issue and performing transcranial brain hemorrhage detection. Significance: This work provides a novel ResAttU-Net-based DL-MITAT paradigm and paves a compelling route for transcranial brain hemorrhage detection as well as other transcranial brain imaging applications.
Source: IEEE Transactions on Biomedical Engineering - July 21, 2023 Category: Biomedical Engineering Source Type: research

How John Fetterman Came Out of the Darkness
When he looks back on the past year—a year in which he nearly died, became a U.S. Senator, and nearly died again—it is the debate that John Fetterman identifies as the ­breaking point. “The debate lit the mitch,” he says, then shakes his head in frustration and tries again. The right word is there in his brain, but he struggles to get it out. “Excuse me, that should be lit the mitch—” He stops and tries again. “Lit the match,” he says finally. Oct. 25, 2022: the date is lodged in his mind. “I knew I had to do it,” he tells me. “I knew that the vote...
Source: TIME: Health - July 20, 2023 Category: Consumer Health News Authors: Molly Ball Tags: Uncategorized Congress Cover Story Exclusive feature uspoliticspolicy Source Type: news

HIT-Heparin Induced Thrombocytopenia Simulation Case
Discussion: The simulation improved awareness of the symptoms of HIT and contraindications of immediate platelet and/or heparin initiation upon vessel occlusion and thrombocytopenia discovery.Topics: Heparin-induced thrombocytopenia, pain control, resuscitation efforts, coagulation disorders, history taking, undifferentiated patient, arterial occlusion, hematology, emergency medicine simulation.PMID:37465544 | PMC:PMC10332759 | DOI:10.21980/J89Q0M
Source: Pain Physician - July 19, 2023 Category: Anesthesiology Authors: Shaza Aouthmany Alyssa Siano De Ante' Russ Mark Bustillo Source Type: research

Identification of a miRNA –mRNA regulatory network for post-stroke depression: a machine-learning approach
ConclusionThe study highlighted gene signatures for PSD with three genes (SPATA2, ZNF208, and YTHDC1) and four upstream miRNAs (miR-6883-5p, miR-6873-3p, miR-4776-3p, and miR-6738-3p). These biomarkers could further our understanding of the pathogenesis of PSD.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research