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Total 1637 results found since Jan 2013.

Spouses of stroke survivors may be at risk for poor cognitive functioning: a cross-sectional population-based study.
CONCLUSIONS: Spousal caregivers of stroke survivors may be at risk for poor cognitive functioning. More work is needed to identify the processes that may contribute to the diminished cognitive capacity among these adults so that interventions may be developed to reduce caregiver burden and promote cognitive health. PMID: 23893836 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - July 1, 2013 Category: Neurology Authors: Chen P, Botticello AL Tags: Top Stroke Rehabil Source Type: research

Intima-Media Thickness and Cognitive Function in Stroke-Free Middle-Aged Adults: Findings From the Coronary Artery Risk Development in Young Adults Study Clinical Sciences
Conclusions— We observed an association between greater IMT and worse processing speed—a key component of cognitive functioning—at middle age above and beyond traditional vascular risk factors. Efforts targeted at preventing early stages of atherosclerosis may modify the course of cognitive aging.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Al Hazzouri, A. Z., Vittinghoff, E., Sidney, S., Reis, J. P., Jacobs, D. R., Yaffe, K. Tags: Cerebrovascular disease/stroke, Risk Factors, Epidemiology Clinical Sciences Source Type: research

Error augmentation as a possible technique for improving upper extremity motor performance after a stroke - a systematic review.
CONCLUSIONS: Most of the studies reviewed have significant methodological drawbacks that resulted in equivocal results. Therefore, we recommend that additional randomized controlled trials, with larger sample sizes and acceptable protocols be conducted to determine the long-term efficacy of EA training. PMID: 26382572 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 18, 2015 Category: Neurology Authors: Israely S, Carmeli E Tags: Top Stroke Rehabil Source Type: research

Stroke Severity Is a Crucial Predictor of Outcome: An International Prospective Validation Study Stroke
Conclusions In this prospective pilot study, the baseline NIHSS score was essential for prediction of acute ischemic stroke outcomes, followed by age; whereas traditional comorbidity index contributed little to the overall model. Future studies of stroke outcomes between different care systems will benefit from including a baseline NIHSS score.
Source: JAHA:Journal of the American Heart Association - January 21, 2016 Category: Cardiology Authors: Rost, N. S., Bottle, A., Lee, J.-M., Randall, M., Middleton, S., Shaw, L., Thijs, V., Rinkel, G. J. E., Hemmen, T. M., the Global Comparators Stroke GOAL collaborators Tags: Mortality/Survival, Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Source Type: research

Effects of action observation therapy on hand dexterity and EEG-based cortical activation patterns in patients with post-stroke hemiparesis.
CONCLUSIONS: These findings support that AOT may be beneficial in altering cortical activation patterns and hand dexterity. PMID: 27077994 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 30, 2016 Category: Neurology Authors: Kuk EJ, Kim JM, Oh DW, Hwang HJ Tags: Top Stroke Rehabil Source Type: research

Boosting the traditional physiotherapist approach for stroke spasticity using a sensorized ankle foot orthosis: a pilot study.
CONCLUSIONS: PhT-Pt sharing of exercise information, provided by joint sensorization and vBFB, improved the efficacy of the conventional approach for treating ankle spasticity in subacute stroke Pts. PMID: 28460597 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - May 1, 2017 Category: Neurology Authors: Tamburella F, Moreno JC, Iosa M, Pisotta I, Cincotti F, Mattia D, Pons JL, Molinari M Tags: Top Stroke Rehabil Source Type: research

Novel Screening Tool for Stroke Using Artificial Neural Network Brief Report
Conclusions—Our results show that ANN can be an effective tool for the recognition of ACI and differentiation of ACI from stroke mimics at the initial examination.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Vida Abedi, Nitin Goyal, Georgios Tsivgoulis, Niyousha Hosseinichimeh, Raquel Hontecillas, Josep Bassaganya-Riera, Lucas Elijovich, Jeffrey E. Metter, Anne W. Alexandrov, David S. Liebeskind, Andrei V. Alexandrov, Ramin Zand Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Differences in neural pathways are related to the short- or long-term benefits of constraint-induced movement therapy in patients with chronic stroke and hemiparesis: a pilot cohort study.
Conclusions The integrity of the affected corticospinal and non-corticospinal motor pathways was associated with CIMT-induced motor learning at least 6 months after CIMT. PMID: 29130404 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - November 13, 2017 Category: Neurology Authors: Takebayashi T, Marumoto K, Takahashi K, Domen K Tags: Top Stroke Rehabil Source Type: research

A short bout of high-intensity exercise alters ipsilesional motor cortical excitability post-stroke.
Conclusions: High-intensity exercise can increase lesioned hemisphere motor cortical excitability in a non-exercised muscle post-stroke. Our short and clinically-advantageous exercise protocol shows promise as a potential priming method in stroke rehabilitation. PMID: 31144609 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - May 29, 2019 Category: Neurology Authors: Li X, Charalambous CC, Reisman DS, Morton SM Tags: Top Stroke Rehabil Source Type: research

Efficacy of motor imagery additional to motor-based therapy in the recovery of motor function of the upper limb in post-stroke individuals: a systematic review.
Conclusion. There is evidence showing that MI associated with motor-based therapy is an effective tool in improving the motor function of upper limbs of post-stroke individuals. However, more studies are needed to establish criteria for frequency and duration of intervention, and what better type of MI should be used. PMID: 31264520 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - July 1, 2019 Category: Neurology Authors: Machado TC, Carregosa AA, Santos MS, Ribeiro NMDS, Melo A Tags: Top Stroke Rehabil Source Type: research

A multifaceted continuing professional development intervention to move stroke rehabilitation guidelines into professional practice: A feasibility study.
Conclusion: This study demonstrated the feasibility of assessing the impact of a CPD intervention in stroke rehabilitation uptake and informed the design of a research program aimed at increasing the use of stroke evidence-based rehabilitation interventions. PMID: 31960782 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - January 20, 2020 Category: Neurology Authors: Luconi F, Rochette A, Grad R, Hallé MC, Chin D, Habib B, Thomas A Tags: Top Stroke Rehabil Source Type: research

Cognition assessments to predict inpatient falls in a subacute stroke rehabilitation setting.
Conclusions: Cognition assessments, i.e., one FIM item, one RAVLT item, or a one-minute verbal fluency test are significant falls predictors. PMID: 32431244 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - May 19, 2020 Category: Neurology Authors: García-Rudolph A, García-Molina A, Opisso E, Tormos JM, Bernabeu M Tags: Top Stroke Rehabil Source Type: research

Verbal feedback enhances motor learning during post-stroke gait retraining.
CONCLUSIONS: Addition of individualized verbal feedback (FF+PT) to a single session of gait training may enhance within- and across-session learning of targeted gait variables in people post-stroke, and merits more investigation. PMID: 32942960 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 17, 2020 Category: Neurology Authors: Rendos NK, Zajac-Cox L, Thomas R, Sato S, Eicholtz S, Kesar TM Tags: Top Stroke Rehabil Source Type: research

Survivor gives us a lens into regional systems of care for acute ischemic stroke in North Dakota
I just got back from the North Dakota Mission: Lifeline STEMI and Acute Stroke Conference in Bismark, ND. I had a great time and I learned a lot. I often get asked to speak in various venues about acute STEMI and 12-lead ECG interpretation, but for this conference they wanted me to talk mostly about stroke. That turned out to be a good thing because it forced me to read the 2013 AHA / ASA Guildelines for the Early Management of Patients With Acute Ischemic Stroke to make sure I was asking intelligent questions during the panel discussion (which I moderated) and also giving accurate information for the class I taught about ...
Source: EMS 12-Lead - May 31, 2013 Category: Cardiology Authors: Tom Bouthillet Tags: ems-topics patient-management North Dakota Mission Lifeline Stroke Source Type: research

Initial Experience with Upfront Arterial and Perfusion Imaging among Ischemic Stroke Patients Presenting within the 4.5-hour Time Window
Conclusions: An upfront CTA/CTP protocol aided stroke team decision-making in nearly half of cases. Implementation of a CTA/CTP protocol was associated with a learning curve of 6 months before door to needle time ≤60 minutes returned to similar rates as the pre-CTA/CTP protocol.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Ali Reza Noorian, Katja Bryant, Ashley Aiken, Andrew D. Nicholson, Adam B. Edwards, Mason P. Markowski, Seena Dehkharghani, Jemisha C. Bouloute, Jacquelyn Abney, Fadi Nahab Tags: Original Articles Source Type: research

Direct Thrombin Inhibitor Argatroban Reduces Stroke Damage in 2 Different Models Brief Reports
Conclusions— We obtained supportive evidence for argatroban protection of the neurovascular unit using behavioral and histological measurements at realistic therapeutic time windows.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Lyden, P., Pereira, B., Chen, B., Zhao, L., Lamb, J., Lei, I.-f., Rajput, P. Tags: Other anticoagulants, Other Treatment, Emergency treatment of Stroke, Other Vascular biology Brief Reports Source Type: research

A Smartphone Application To Aid In The Evaluation, Treatment, And Clinical Trial Enrollment Of The Acute Stroke Patient (P7.125)
CONCLUSION: A smartphone application that centralizes various disparate resources may allow for more efficient management of the acute stroke patient. Further, such an application may allow easy screening for clinical trials by new practitioners as they learn of the various inclusion criteria for their studies.Disclosure: Dr. Nguyen has received royalty, or license fee, or contractual rights payments from the University of Texas. Dr. Wu has nothing to disclose. Dr. Barreto has nothing to disclose. Dr. Grotta has received personal compensation for activities with Lundbeck as a consultant. Dr. Savitz has received personal co...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Nguyen, C., Wu, T.-C., Barreto, A., Grotta, J., Savitz, S. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

Cognitive performance after stroke – The Framingham Heart Study
ConclusionsClinical stroke is associated with subsequent poorer performance in multiple cognitive domains. This association cannot be entirely explained by the individual's cognitive function prior to stroke or by concomitant vascular risk factor levels.
Source: International Journal of Stroke - April 1, 2014 Category: Neurology Authors: Galit Weinstein, Sarah R. Preis, Alexa S. Beiser, Rhoda Au, Margaret Kelly‐Hayes, Carlos S. Kase, Philip A. Wolf, Sudha Seshadri Tags: Research Source Type: research

Delayed Hyperbaric Oxygen Therapy Promotes Neurogenesis Through Reactive Oxygen Species/Hypoxia-Inducible Factor-1{alpha}/{beta}-Catenin Pathway in Middle Cerebral Artery Occlusion Rats Basic Sciences
Conclusions— Delayed HBO enhanced endogenous neurogenesis and improved neurofunctional recovery in the late-chronic phase of stroke possibly mediated by ROS/HIF-1α/β-catenin pathway. Delayed HBO may serve as an alternative treatment to improve long-term recovery of stroke survivors.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Hu, Q., Liang, X., Chen, D., Chen, Y., Doycheva, D., Tang, J., Tang, J., Zhang, J. H. Tags: Animal models of human disease, Other Stroke Treatment - Medical Basic Sciences Source Type: research

Determining the barriers and facilitators to adopting best practices in the management of poststroke unilateral spatial neglect: results of a qualitative study.
Conclusion: It is estimated that upwards of 40% of patients experience poststroke USN in the acute phase, and we have evidence of poor early management. This study identified several modifiable factors that prepare the ground for the creation and testing of a multimodal knowledge translation intervention aimed at improving clinicians' best practice management of poststroke USN. PMID: 24985390 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - May 1, 2014 Category: Neurology Authors: Petzold A, Korner-Bitensky N, Salbach NM, Ahmed S, Menon A, Ogourtsova T Tags: Top Stroke Rehabil Source Type: research

Testing devices for the prevention and treatment of stroke and its complications
We are entering a challenging but exciting period when many new interventions may appear for stroke based on the use of devices. Hopefully these will lead to improved outcomes at a cost that can be afforded in most parts of the world. Nevertheless, it is vital that lessons are learnt from failures in the development of pharmacological interventions (and from some early device studies), including inadequate preclinical testing, suboptimal trial design and analysis, and underpowered studies. The device industry is far more disparate than that seen for pharmaceuticals; companies are very variable in size and experience in str...
Source: International Journal of Stroke - July 17, 2014 Category: Neurology Authors: Philip M. Bath, Michael Brainin, Chloe Brown, Bruce Campbell, Stephen M. Davis, Geoffrey A. Donnan, Gary A. Ford, Werner Hacke, Cynthia Iglesias, Kennedy R. Lees, Stacey S. Pugh, Jeff L. Saver, Peter D. Schellinger, Thomas Truelsen Tags: Opinion Source Type: research

Cognitive dysfunction after on-pump operations: neuropsychological characteristics and optimal core battery of tests.
Authors: Polunina AG, Golukhova EZ, Guekht AB, Lefterova NP, Bokeria LA Abstract Postoperative cognitive dysfunction (POCD) is a mild form of perioperative ischemic brain injury, which emerges as memory decline, decreased attention, and decreased concentration during several months, or even years, after surgery. Here we present results of our three neuropsychological studies, which overall included 145 patients after on-pump operations. We found that the auditory memory span test (digit span) was more effective as a tool for registration of POCD, in comparison with the word-list learning and story-learning tests. N...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Modification of the ladder rung walking task-new options for analysis of skilled movements.
Authors: Antonow-Schlorke I, Ehrhardt J, Knieling M Abstract Method sensitivity is critical for evaluation of poststroke motor function. Skilled walking was assessed in horizontal, upward, and downward rung ladder walking to compare the demands of the tasks and test sensitivity. The complete step sequence of a walk was subjected to analysis aimed at demonstrating the walking pattern, step sequence, step cycle, limb coordination, and limb interaction to complement the foot fault scoring system. Rats (males, n = 10) underwent unilateral photothrombotic lesion of the motor cortex of the forelimb and hind limb areas. L...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Methodology of the Stroke Self-Management Rehabilitation Trial: An International, Multisite Pilot Trial
Stroke is a major cause of long-term adult disability with many survivors living in the community relying on family members for on-going support. However, reports of inadequate understanding of rehabilitation techniques are common. A self-management DVD-based observational learning tool may help improve functional outcomes for survivors of stroke and reduce caregivers' burden.
Source: Journal of Stroke and Cerebrovascular Diseases - December 9, 2014 Category: Neurology Authors: Kelly M. Jones, Rohit Bhattacharjee, Rita Krishnamurthi, Sarah Blanton, Alice Theadom, Suzanne Barker-Collo, Amanda Thrift, Priya Parmar, Annick Maujean, Annemarei Ranta, Emmanuel Sanya, Valery L. Feigin, SMART Study Group Source Type: research

Cognition and major depression after frontal and cerebellar stroke (P7.133)
CONCLUSIONS: Results in individuals with frontal lobe CVA were consistent with previous studies showing associations between cognition and depression in other neurologic disease. Disconnection and disruption in brain regions involving both emotion regulation and cognition may explain these associations. Alternatively, or simultaneously, depression may transiently impair cognitive test performance after frontal lobe stroke. Study Supported by:Disclosure: Dr. Dulay has nothing to disclose. Dr. Agbayani has nothing to disclose. Dr. Gadhia has nothing to disclose. Dr. Lai has nothing to disclose. Dr. Volpi has nothing to discl...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Dulay, M., Agbayani, K., Gadhia, R., Lai, J., Volpi, J., Chiu, D., Zhang, Y. J., Britz, G. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke, Depression, and Anxiety Source Type: research

Delayed Administration of Tat-HA-NR2B9c Promotes Recovery After Stroke in Rats Basic Sciences
Conclusions— Dissociating N-methyl-d-aspartate receptor–postsynaptic density protein-95 coupling by Tat-HA-NR2B9c in the subacute phase after stroke promotes functional recovery, probably because of that it increases neurogenesis and dendritic spine density of mature neurons via regulating cyclin-dependent kinase 5 in the ischemic brain.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Zhou, H.-H., Tang, Y., Zhang, X.-Y., Luo, C.-X., Gao, L.-Y., Wu, H.-Y., Chang, L., Zhu, D.-Y. Tags: Animal models of human disease, Neuroprotectors Basic Sciences Source Type: research

Prophylactic Edaravone Prevents Transient Hypoxic-Ischemic Brain Injury: Implications for Perioperative Neuroprotection Basic Sciences
Conclusions— Acute application of Edaravone may be a useful strategy to prevent postsurgery stroke and cognitive impairment, especially in patients with severe carotid stenosis.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Sun, Y.-Y., Li, Y., Wali, B., Li, Y., Lee, J., Heinmiller, A., Abe, K., Stein, D. G., Mao, H., Sayeed, I., Kuan, C.-Y. Tags: Animal models of human disease, Other Stroke Treatment - Medical, Coagulation and fibronolysis Basic Sciences Source Type: research

Executive function, but not memory, associates with incident coronary heart disease and stroke
Conclusion: Lower executive function, but not memory, is associated with higher risk of coronary heart disease and stroke. Lower executive function, as an independent risk indicator, might better reflect brain vascular pathologies.
Source: Neurology - August 31, 2015 Category: Neurology Authors: Rostamian, S., van Buchem, M. A., Westendorp, R. G. J., Jukema, J. W., Mooijaart, S. P., Sabayan, B., de Craen, A. J. M. Tags: All Cerebrovascular disease/Stroke, Cardiac, Cognitive aging, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Transcranial direct current stimulation facilitates motor learning post-stroke: a systematic review and meta-analysis
Transcranial direct current stimulation (tDCS) is an attractive protocol for stroke motor recovery. The current systematic review and meta-analysis investigated the effects of tDCS on motor learning post-stroke. Specifically, we determined long-term learning effects by examining motor improvements from baseline to at least 5 days after tDCS intervention and motor practise. 17 studies reported long-term retention testing (mean retention interval=43.8 days; SD=56.6 days) and qualified for inclusion in our meta-analysis. Assessing primary outcome measures for groups that received tDCS and motor practise versus ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 15, 2016 Category: Neurosurgery Authors: Kang, N., Summers, J. J., Cauraugh, J. H. Tags: Editor's choice, Stroke Cerebrovascular disease Source Type: research

Trends in mortality following mechanical thrombectomy for the treatment of acute ischemic stroke in the USA
Conclusions Utilization of MT represents a small percentage of stroke cases, although the trend is increasing. Mortality following MT has been showing a steady decline over the past 5 years. This may be a result of a learning curve, improved patient selection, and/or device improvements. Randomized trials remain essential to evaluate the potential benefit of endovascular devices and identify the most appropriate patients.
Source: Journal of NeuroInterventional Surgery - April 13, 2016 Category: Neurosurgery Authors: Villwock, M. R., Padalino, D. J., Deshaies, E. M. Tags: Ischemic stroke Source Type: research

Brain stimulation and constraint for perinatal stroke hemiparesis: The PLASTIC CHAMPS Trial
Conclusions: Hemiparetic children participating in intensive, psychosocial rehabilitation programs can achieve sustained functional gains. Addition of CIMT and rTMS increases the chances of improvement. Classification of evidence: This study provides Class II evidence that combined rTMS and CIMT enhance therapy-induced functional motor gains in children with stroke-induced hemiparetic cerebral palsy.
Source: Neurology - May 1, 2016 Category: Neurology Authors: Kirton, A., Andersen, J., Herrero, M., Nettel-Aguirre, A., Carsolio, L., Damji, O., Keess, J., Mineyko, A., Hodge, J., Hill, M. D. Tags: All Rehabilitation, Plasticity, TMS, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke ARTICLE Source Type: research

Transcranial direct current stimulation for children with perinatal stroke and hemiparesis
Conclusion: tDCS trials appear feasible and safe in hemiparetic children. Lack of change in objective motor function may reflect underdosing of therapy. Marked gains in subjective function with tDCS warrant further study. ClinicalTrials.gov identifier: NCT02170285. Classification of evidence: This study provides Class II evidence that for children with perinatal stroke and hemiparetic cerebral palsy, the addition of tDCS to moderate-dose motor learning therapy does not significantly improve motor function as measured by the AHA.
Source: Neurology - January 15, 2017 Category: Neurology Authors: Kirton, A., Ciechanski, P., Zewdie, E., Andersen, J., Nettel-Aguirre, A., Carlson, H., Carsolio, L., Herrero, M., Quigley, J., Mineyko, A., Hodge, J., Hill, M. Tags: Childhood stroke, Clinical trials Randomized controlled (CONSORT agreement), All Rehabilitation, Plasticity, TMS ARTICLE Source Type: research

Development and Feasibility of a Canine Endovascular Reversible Middle Cerebral Artery Occlusion Stroke Model: a Novel anterior circulation approach (P1.267)
Conclusions:Here we report the successful development of an endovascular reversible MCAo model in the canine by an anterior circulation approach. A learning curve is seen in the successful implementation of this model, as shown by our results.Disclosure: Dr. Guada has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Watanabe has nothing to disclose. Dr. Sidani has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Guada, L., Ramdas, K., Atchaneeyasakul, K., Watanabe, M., Sidani, C., Yavagal, D. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Assessment Model to Identify Patients With Stroke With a High Possibility of Discharge to Home Clinical Sciences
Conclusions—We have developed an assessment model for identifying patients with a high possibility of being discharged to their homes after an acute stroke. This model would be useful for health professionals to adequately plan patients’ discharge soon after their admission.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Takahiro Itaya, Yusuke Murakami, Akiko Ota, Eiichi Nomura, Tomoko Fukushima, Masakazu Nishigaki Tags: Epidemiology, Quality and Outcomes Original Contributions Source Type: research

Growth Hormone Improves Cognitive Function After Experimental Stroke Basic Sciences
Conclusions—These findings provide compelling preclinical evidence for the usage of GH as a potential therapeutic tool in the recovery phase of patients after stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Lin Kooi Ong, Wei Zhen Chow, Clifford TeBay, Murielle Kluge, Giovanni Pietrogrande, Katarzyna Zalewska, Patricia Crock, N. David Aberg, Andrew Bivard, Sarah J. Johnson, Frederick R. Walker, Michael Nilsson, Jorgen Isgaard Tags: Angiogenesis, Basic Science Research, Growth Factors/Cytokines, Cognitive Impairment, Neurogenesis Original Contributions Source Type: research

Predicting Motor and Cognitive Improvement Through Machine Learning Algorithm in Human Subject that Underwent a Rehabilitation Treatment in the Early Stage of Stroke
The objective of this study was to investigate, in subject with stroke, the exact role as prognostic factor of common inflammatory biomarkers and other markers in predicting motor and/or cognitive improvement after rehabilitation treatment from early stage of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 2, 2018 Category: Neurology Authors: Patrizio Sale, Giorgio Ferriero, Lucio Ciabattoni, Anna Maria Cortese, Francesco Ferracuti, Luca Romeo, Francesco Piccione, Stefano Masiero Source Type: research

Automating Ischemic Stroke Subtype Classification Using Machine Learning and Natural Language Processing
This study sought to use natural language processing of electronic health records (EHR) combined with machine learning methods to automate IS subtyping. Methods: Among IS patients from an observational registry with TOAST subtyping adjudicated by board-certified vascular neurologists, we analyzed unstructured text-based EHR data including neurology progress notes and neuroradiology reports using natural language processing.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2019 Category: Neurology Authors: Ravi Garg, Elissa Oh, Andrew Naidech, Konrad Kording, Shyam Prabhakaran Source Type: research

Texture Features of Magnetic Resonance Images: an Early Marker of Post-stroke Cognitive Impairment
AbstractStroke is frequently associated with delayed, long-term cognitive impairment (CI) and dementia. Recent research has focused on identifying early predictive markers of CI occurrence. We carried out a texture analysis of magnetic resonance (MR) images to identify predictive markers of CI occurrence based on a combination of preclinical and clinical data. Seventy-two-hour post-stroke T1W MR images of 160 consecutive patients were examined, including 75 patients with confirmed CI at the 6-month post-stroke neuropsychological examination. Texture features were measured in the hippocampus and entorhinal cortex and compar...
Source: Translational Stroke Research - October 31, 2019 Category: Neurology Source Type: research

Validity of quantitative assessment of posterior pelvic tilt and contralateral vaulting in hemiplegia using 3D treadmill gait analysis.
CONCLUSIONS: The proposed indices for posterior pelvic tilt and contralateral vaulting are useful for clinical gait analysis, and thus encouraging a more detailed analysis of hemiplegic gait using a motion analysis system. PMID: 32588758 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - June 25, 2020 Category: Neurology Authors: Tanikawa H, Inagaki K, Ohtsuka K, Matsuda F, Mukaino M, Yamada J, Kanada Y, Kagaya H, Saitoh E Tags: Top Stroke Rehabil Source Type: research

Machine Learning for Brain Stroke: A Review
Machine Learning (ML) delivers an accurate and quick prediction outcome and it has become a powerful tool in health settings, offering personalized clinical care for stroke patients. An application of ML and Deep Learning in health care is growing however, some research areas do not catch enough attention for scientific investigation though there is real need of research. Therefore, the aim of this work is to classify state-of-arts on ML techniques for brain stroke into 4 categories based on their functionalities or similarity, and then review studies of each category systematically.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Manisha Sanjay Sirsat, Eduardo Ferm é, Joana Câmara Tags: Review Article Source Type: research

Uric Acid and Gluconic Acid as Predictors of Hyperglycemia and Cytotoxic Injury after Stroke
AbstractHyperglycemia is a feature of worse brain injury after acute ischemic stroke, but the underlying metabolic changes and the link to cytotoxic brain injury are not fully understood. In this observational study, we applied regression and machine learning classification analyses to identify metabolites associated with hyperglycemia and a neuroimaging proxy for cytotoxic brain injury. Metabolomics and lipidomics were carried out using liquid chromatography-tandem mass spectrometry in admission plasma samples from 381 patients presenting with an acute stroke. Glucose was measured by a central clinical laboratory, and a s...
Source: Translational Stroke Research - October 17, 2020 Category: Neurology Source Type: research

Development and Validation of Machine Learning-Based Prediction for Dependence in the Activities of Daily Living after Stroke Inpatient Rehabilitation: A Decision-Tree Analysis
This study aimed to develop and assess the CPRs using machine learning-based methods to identify ADL dependence in stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2020 Category: Neurology Authors: Yuji Iwamoto, Takeshi Imura, Ryo Tanaka, Naoki Imada, Tetsuji Inagawa, Hayato Araki, Osamu Araki Source Type: research

Clinical Features for Identifying the Possibility of Toileting Independence after Convalescent Inpatient Rehabilitation in Severe Stroke Patients: A Decision Tree Analysis Based on a Nationwide Japan Rehabilitation Database
This study aimed to identify the factors affecting toileting independence in severe stroke patients using ML.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2020 Category: Neurology Authors: Takeshi Imura, Yu Inoue, Ryo Tanaka, Junji Matsuba, Yasutaka Umayahara Source Type: research

Decision Tree Algorithm Identifies Stroke Patients Likely Discharge Home After Rehabilitation Using Functional and Environmental Predictors
The importance of environmental factors for stroke patients to achieve home discharge was not scientifically proven. There are limited studies on the application of the decision tree algorithm with various functional and environmental variables to identify stroke patients with a high possibility of home discharge. The present study aimed to identify the factors, including functional and environmental factors, affecting home discharge after stroke inpatient rehabilitation using the machine learning method.
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2021 Category: Neurology Authors: Takeshi Imura, Yuji Iwamoto, Tetsuji Inagawa, Naoki Imada, Ryo Tanaka, Haruki Toda, Yu Inoue, Hayato Araki, Osamu Araki Source Type: research

Alberta Stroke Program Early CT Score Calculation Using the Deep Learning-Based Brain Hemisphere Comparison Algorithm
The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is a promising tool for the evaluation of stroke expansion to determine suitability for reperfusion therapy. The aim of this study was to validate deep learning-based ASPECTS calculation software that utilizes a three-dimensional fully convolutional network-based brain hemisphere comparison algorithm (3D-BHCA).
Source: Journal of Stroke and Cerebrovascular Diseases - April 17, 2021 Category: Neurology Authors: Masaki Naganuma, Atsushi Tachibana, Takuya Fuchigami, Sadato Akahori, Shuichiro Okumura, Kenichiro Yi, Yoshimasa Matsuo, Koichi Ikeno, Toshiro Yonehara Source Type: research

Use of artificial intelligence as an instrument of evaluation after stroke: a scoping review based on international classification of functioning, disability and health concept
Conclusion: The prevailing research themes demonstrated the growing utility of AI algorithms for stroke evaluation.PMID:34115576 | DOI:10.1080/10749357.2021.1926149
Source: Topics in Stroke Rehabilitation - June 11, 2021 Category: Neurology Authors: Gustavo Jos é Luvizutto Gabrielly Fernanda Silva Monalisa Resende Nascimento Kelly Cristina Sousa Santos Pablo Andrei Appelt Eduardo de Moura Neto Juli Thomaz de Souza Fernanda Cristina Wincker Luana Aparecida Miranda Pedro Tadao Hamamoto Filho Luciane A Source Type: research