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Total 131 results found since Jan 2013.

Rural versus metropolitan comparison of processes of care in the community-based management of TIA and minor stroke in Australia (an analysis from the INSIST study)
CONCLUSIONS: Although TIAMS prognosis in rural settings where solely GP care is common is very good, the processes of care in such areas are inferior to metropolitan. This suggests there is further scope to support rural GPs to optimise care of TIAMS patients.PMID:36382851 | DOI:10.1111/ajr.12950
Source: The Australian Journal of Rural Health - November 16, 2022 Category: Rural Health Authors: Shyam Gangadharan Shinya Tomari Christopher R Levi Natasha Weaver Elizabeth Holliday Beata Bajorek Daniel Lasserson Jose M Valderas Helen M Dewey Peter Alan Barber Neil J Spratt Dominique A Cadilhac Valery L Feigin Peter M Rothwell Hossein Zareie Carlos G Source Type: research

Perspectives on Encouraging Diversity and Inclusion Among Stroke Rehabilitation Research Teams
To describe dimensions of personal and professional diversity and inclusion present within a single National Institutes of Health R01 funded stroke rehabilitation research team, using a conceptual, literature-based approach (DHHS, 2022; Hall et al., 2018; Wood et al., 2021). To explore the potential impact of diversity dimensions on the research team's activities.
Source: Archives of Physical Medicine and Rehabilitation - March 1, 2023 Category: Rehabilitation Authors: Lorelei Johnson, Tami Guerrier, Mark Hirsch, Adam Jacks, Soomin Kim, Marcia Rodriguez, J George Thomas, Kim Welsh, Katarina Haley Tags: Late Breaking Research Poster 2229369 Source Type: research

Study protocol for development and validation of a single tool to assess risks of stroke, diabetes mellitus, myocardial infarction and dementia: DemNCD-Risk
Introduction Current efforts to reduce dementia focus on prevention and risk reduction by targeting modifiable risk factors. As dementia and cardiometabolic non-communicable diseases (NCDs) share risk factors, a single risk-estimating tool for dementia and multiple NCDs could be cost-effective and facilitate concurrent assessments as compared with a conventional single approach. The aim of this study is to develop and validate a new risk tool that estimates an individual’s risk of developing dementia and other NCDs including diabetes mellitus, stroke and myocardial infarction. Once validated, it could be used by the ...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Kootar, S., Huque, M. H., Kiely, K. M., Anderson, C. S., Jorm, L., Kivipelto, M., Lautenschlager, N. T., Matthews, F., Shaw, J. E., Whitmer, R. A., Peters, R., Anstey, K. J. Tags: Open access, Public health Source Type: research

IJERPH, Vol. 20, Pages 4694: Exploring the Association between Individual-Level Attributes and Fidelity to a Vocational Rehabilitation Intervention within a Randomised Controlled Trial
This study aimed to explore the relationships between attributes of Occupational Therapists (OTs), their faithful delivery of an early stroke specialist vocational rehabilitation intervention (ESSVR), and stroke survivor return-to-work (RTW) outcomes. Thirty-nine OTs were surveyed about their experience and knowledge of stroke and vocational rehabilitation and were trained to deliver ESSVR. ESSVR was delivered across 16 sites in England and Wales between February 2018 and November 2021. OTs received monthly mentoring to support ESSVR delivery. The amount of mentoring each OT received was recorded in OT mentoring records. F...
Source: International Journal of Environmental Research and Public Health - March 7, 2023 Category: Environmental Health Authors: Katie E. Powers Roshan das Nair Julie Phillips Amanda Farrin Kathryn A. Radford Tags: Article Source Type: research

Cerebrovascular Disease Profiles of Culturally and Linguistically Diverse Communities in South Western Sydney and New South Wales
Conclusion: Greater rates of TIA/stroke were observed in specific CALD communities, with increased rates of cerebrovascular risk factors. Culturally specific, targeted interventions may bridge health inequalities in cerebrovascular disease.Cerebrovasc Dis
Source: Cerebrovascular Diseases - May 12, 2022 Category: Neurology Source Type: research

Phagocytosis in the Brain: Homeostasis and Disease
Conclusions and Perspectives In this review we have summarized the critical role phagocytosis plays in both CNS homeostasis and disease. While much progress has been made in recent years, many unanswered questions remain. How phagocytosis in the CNS is influenced by numerous factors, such as microenvironment or phagocytic target, have yet to be fully resolved. Additionally, the utilization of novel technologies, including in vivo imaging techniques (217), iPSC-derived microglia (213) and high-throughput screens (66), will likely contribute to further identification of phagocytic pathways and consequences of phagocytosis w...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Googling service boundaries for Endovascular Clot Retrieval (ECR) hub hospitals in metropolitan Sydney
Conclusions: The simulation studies supported a minimum of 4 ECR hubs servicing Sydney. This model provides data on number of suburbs and population at risk of stroke that can reach these hubs within 30 minutes.
Source: Frontiers in Neurology - July 1, 2019 Category: Neurology Source Type: research

Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomized Clinical Trial
Conclusions This small trial showed that SAPT (vs. DAPT) tended to reduce the occurrence of major adverse events following TAVR. SAPT reduced the risk for major or life-threatening events while not increasing the risk for MI or stroke. Larger studies are needed to confirm these results. (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation: The ARTE Trial [ARTE], NCT01559298; Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVI [ARTE], NCT02640794)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - July 3, 2017 Category: Cardiology Authors: Rodes-Cabau, J., Masson, J.-B., Welsh, R. C., Garcia del Blanco, B., Pelletier, M., Webb, J. G., Al-Qoofi, F., Genereux, P., Maluenda, G., Thoenes, M., Paradis, J.-M., Chamandi, C., Serra, V., Dumont, E., Cote, M. Tags: Structural Source Type: research

Glutamate Transport and Preterm Brain Injury
Silvia Pregnolato1*, Elavazhagan Chakkarapani1, Anthony R. Isles2 and Karen Luyt1 1Department of Neonatal Neurology, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom 2Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and beh...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Age-Dependence of Flow Homeostasis in the Left Ventricle
Conclusions: In average, blood spends 1 to 3 beats inside the LV with very low shear stress rates. The apical region is the most prone to blood stasis, particularly in mid-aged adults. The washout of blood in the normal LV is age-dependent due to physiological changes in the degree of apical penetration of the filling waves. Introduction Cardioembolic stroke is a major source of mortality and disability worldwide and blood stasis one of its major determinants (Adams et al., 1986). Left ventricular (LV) function has evolved to maximize mechanical efficiency and ensure organ perfusion at a low cost of energy and fill...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research

Elsberg Syndrome, Lumbosacral Radiculopathy, and Myelitis Due to Herpes Zoster in a Patient With Smoldering Myeloma
J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096211063348. doi: 10.1177/23247096211063348.ABSTRACTHerpes zoster (HZ) is a common illness caused by the reactivation of latent varicella zoster virus (VZV) due to waning immunity, often secondary to old age or an underlying immunocompromised state. Its complications can manifest in variety of ways, including persistent neuralgias, vasculopathies, and stroke. Here, we describe a case of a 45-year-old man with a history of cryptogenic stroke and smoldering myeloma who was admitted with sacral HZ complicated by right lumbosacral radiculopathy and myelitis, otherwise ...
Source: Herpes - January 25, 2022 Category: Infectious Diseases Authors: Rohan Desai Cynthia T Welsh Samuel O Schumann Source Type: research

A Novel Atrial Fibrillation Evaluation Modelling Solution For NHS
Approximately every fifth stroke in UK is due to AF and costs the UK National Health Service are between $12,000 and $17,500 per stroke. The aim of this study was to undertake a retrospective health economic analysis of the cost-effectiveness and implications related to opportunistic Atrial Fibrillation (AF) screening in primary care and the detection of previously undiagnosed AF cases in patients, and create a novel modelling solution that can empower individual users and organisations in England, Wales and Northern Ireland in their decision making, technology assessment, comparison of various anticoagulation d rug group...
Source: Value in Health - October 1, 2017 Category: International Medicine & Public Health Authors: G Xydopoulos, R Fordham, Z Khanbai Source Type: research

Longitudinal cardiac changes in a SUGEN/Hypoxic Rat Model of Pulmonary Hypertension determined by Cardiac MRI
Conclusion: 5 weeks of SuHx resulted in RV dysfunction and RV hypertrophy. Although RV systolic pressure remained elevated throughout the 8 week study period, RV dysfunction and RV hypertrophy had improved demonstrating adaptive remodelling of the SuHx rat RV to the induced persistent PH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Jayasekera, G., Wilson, K., Buist, H., Hughes, C., Nilsen, M., Church, C., Gallagher, L., Mullin, J., Maclean, M., Holmes, W., Welsh, D., Peacock, A. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Impact of intracranial artery calcification on cerebral hemodynamic changes
ConclusionHeavier IAC might cause generalized artery flow velocity changes and increased pulsatility index, which may indicate high resistance within cerebrovasculature.
Source: Neuroradiology - February 9, 2018 Category: Radiology Source Type: research